Clinical trials: Nutritional Deficiencies
Renal Osteodystrophy
Zoledronic Acid to Prevent Bone Loss After Kidney Transplantation
The purpose of this study is to determine whether zolendronic acid, a third generation bisphosphonate, is effective in preventing bone loss in the first year after kidney transplantation.
- Trial name
- NCT01675089
- Testing
- Zoledronic acid
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- University of Sao Paulo General Hospital
Pseudobulbar Affect (PBA)
Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS
Objectives of the study are to evaluate the safety, tolerability, and efficacy of two different doses of AVP-923 (capsules containing either 30 mg of dextromethorphan hydrobromide and 10 mg of quinidine sulfate [AVP-923-30] or 20…
- Trial name
- STAR (NCT00573443)
- Testing
- dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg, dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg
- Where
- 62 sites in United States, Argentina and 1 more
- Volunteers
- 326 people
- Sponsor
- Avanir Pharmaceuticals
Amyotrophic Lateral Sclerosis
ALS Study Determining Various Biomarkers and Strength Comparison After Exercise
The purpose of this study is to determine the muscle strength of a muscle in the thigh after 12 weeks of home exercise.
- Trial name
- ADVANCE (NCT03201991)
- Testing
- Resistance Exercise Program
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Kansas Medical Center
Malnutrition
Early Enteral Nutritional Supplementation on Patients With Oral and Oropharyngeal Cancer Undergoing Radio(Chemo)Therapy After Surgical
The target population in the present study is Chinese patients with oral and oropharyngeal cancer who plan to receive radio(chemo)therapy after surgical resection in the outpatient department.
- Trial name
- NCT03545490
- Testing
- Early nutritional intervention
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Iron Deficiency Anemia
The Effect of Iron Deficiency Anemia During Pregnancy
Iron deficiency anemia during pregnancy is a significant worldwide health problem, affecting 22% of pregnant women in industrialized countries and 52% in non-industrialized countries.
- Trial name
- NCT02590224
- Testing
- Ferrous bis-glycinate, Ferrous glycine sulphate
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Amyotrophic Lateral Sclerosis
Assessing Perceptual Effects of Interactive Tasks
In this study, we will evaluate how solo, naive listeners perceive the speech of people with amyotrophic lateral sclerosis (ALS) and age-matched speakers produced across interactive and non-interactive contexts with an…
- Trial name
- NCT06828523
- Testing
- Listener judgements of speech produced in different tasks
- Where
- United States
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Penn State University
Anemia, Iron-deficiency
Optimizing Iron Status While Minimizing Morbidity in HIV-infected Ugandan Children
Randomized, placebo-controlled trial of the effect of 84 days of daily iron supplementation on iron status, gut microbiome profile, infectious disease frequency, and HIV disease severity in moderately anemic [hemoglobin 9 - <11…
- Conditions
- Anemia, Iron-deficiency, Iron Deficiency Anemia, Hiv
- Trial name
- NCT03596996
- Testing
- Ferrous Sulfate
- Where
- Uganda
- Volunteers
- 200 people
- Sponsor
- University of Minnesota
Coronary Artery Disease, Postprandial Hyperglycemia
Vitamin D Supplementation in CAD and Postchallenge Hyperglycemia
The main aim of the investigation is to clarify, whether vitamin D supplementation in coronary artery disease patients with vitamin D deficiency and postchallenge hyperglycemia has an impact on endothelial dysfunction and…
- Conditions
- Coronary Artery Disease, Postprandial Hyperglycemia, Vitamin D Deficiency
- Trial name
- NCT01183442
- Testing
- vitamin D
- Where
- Austria
- Volunteers
- 22 people
- Sponsor
- Medical University of Graz
Amyotrophic Lateral Sclerosis
Evaluate the Safety of Neuronata-R® Inj. Suspended With HypoTHermosol® FRS (HTS-FRS) in Patients With ALS
This clinical trial is a single-center, open-label, and phase I clinical trial to Evaluate the Safety of Neuronata-R® Inj. suspended with HypoTHermosol® FRS (HTS-FRS) in Patients with Amyotrophic Lateral Sclerosis.
- Trial name
- NCT06676423
- Testing
- Lenzumestrocel, Riluzole
- Where
- South Korea
- Volunteers
- 8 people
- Sponsor
- Corestemchemon, Inc.
Chronic Heart Failure, Iron Deficiency, Latent
The Prevalence of Iron Deficiency and the Effectiveness of Ferinject® in Patients With HFpEF (ID-HFpEF)
Observational cohort randomized controlled study to study the influence of correction of ID by intravenous injection of ferric carboxymaltose (Ferinject®) on quality of life indicators, functional status in a cohort of patients…
- Trial name
- ID-HFpEF (NCT05793996)
- Testing
- Ferinject, Diet therapy
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Gastrointestinal Dysfunction, Malnutrition
Postoperative GI Dysfunction and Nutrition in Malnourished Cancer Surgery Patients
This is a prospective two-center observational cohort study in adult patients undergoing major abdominal and/or pelvic oncologic surgery with pre-existing malnutrition.
- Conditions
- Gastrointestinal Dysfunction, Malnutrition, Delirium - Postoperative, Abdominal Neoplasm
- Trial name
- GIDNUT (NCT07622888)
- Testing
- Serotonin (e.g., serotonin adipinate), Standard Prokinetic Therapy (excluding serotonin)
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Arma Ltd.
Vitamin D Deficiency, Metabolic Syndrome
Vitamin D Supplementation and Metabolism in Vitamin D Deficient Elderly
The purpose of this study is to examine the effects of Vitamin D supplementation on the reasons (mechanisms) underlying the development of type 2 diabetes, metabolic syndrome (high blood pressure, cholesterol, diabetes, body…
- Trial name
- VitD (NCT01145703)
- Testing
- RDA Vitamin D3 only, Vitamin D2/3 Repletion only, Vitamin D2/3 Repletion + AEX
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Baltimore VA Medical Center
Iron-deficiency, Ferritin Threshold
Defining the Serum Ferritin Concentration in Kenyan Women at Which the Body Senses Iron Depletion and Begins to Upregulate Iron Absorption
The serum or plasma ferritin concentration (referred to hereafter as ferritin) is the most widely used indicator to detect iron deficiency and a low ferritin indicates depleted iron stores.
- Conditions
- Iron-deficiency, Ferritin Threshold, Iron Absorption, Stable Iron Isotopes
- Trial name
- NCT05266703
- Testing
- Isotopically labelled iron sulfate 15mg
- Where
- Kenya
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Anovulation, Amenorrhea
Effects of Gynecological Age on LH Sensitivity to Energy Availability
The purpose of this experiment is to investigate whether the dependence of luteinizing hormone pulsatility on energy availability declines during adolescence.
- Conditions
- Anovulation, Amenorrhea, Infertility, Starvation
- Trial name
- NCT00260286
- Testing
- Energy availability
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Ohio University
Amyotrophic Lateral Sclerosis, Lou Gehrig Disease
Rehabilitation in SOD1 ALS Treated With Tofersen
The primary objective of this study is to document and describe the effects of a personalized rehabilitation program for patients with SOD1 ALS participating in the tofersen expanded access program.
- Conditions
- Amyotrophic Lateral Sclerosis, Lou Gehrig Disease, Familial Amyotrophic Lateral Sclerosis, Motor Neuron Disease
- Trial name
- NCT05725759
- Testing
- Rehabilitation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Washington University School of Medicine
Iron Status, Vitamin A Status
Effect of African Leafy Vegetables on Nutritional Status of South African School Children.
The combination of poverty-related infectious and lifestyle-related non-communicable diseases, both driven by malnutrition, causes a high burden for South Africa.
- Conditions
- Iron Status, Vitamin A Status, Zinc Status, Malnutrition
- Trial name
- ALV (NCT01920646)
- Testing
- ALV
- Where
- South Africa
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- North-West University, South Africa
Multiple Myeloma
Tandem Auto Transplantation in Myeloma Patients With <12 Months of Prior Treatment
This study is designed to decrease toxicity associated with prior tandem transplant protocols by reducing the intensity of induction, consolidation and maintenance therapy, while increasing event-free survival by adding…
- Trial name
- NCT01548573
- Testing
- Dexamethasone, Tandem autologous stem cell transplant, Cisplatin
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Iowa
Amyotrophic Lateral Sclerosis
Peripheral Neurofilament Levels and Amyotrophic Lateral Sclerosis
To evaluate the correlation between peripheral neurofilament levels and clinical subtypes of amyotrophic lateral sclerosis and the severity of peripheral motor axonal involvement.
- Trial name
- NCT04455542
- Testing
- LMND-ALS, UMND-ALS, FAS and FLS
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Peking University Third Hospital
Iron Status
The Relationship Between Iron Status, Cognitive Performance, Subjective Mood and Fatigue in Women of Reproductive Age.
Iron deficiency is the most prevalent nutritional deficiency worldwide with one in four estimated to be affected by iron deficiency anaemia.
- Trial name
- NCT04257669
- Where
- United Kingdom
- Volunteers
- 379 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis (ALS), or "Lou Gehrig's Disease", is a fatal disorder that causes progressive degeneration and weakening of the muscles of breathing, leading to breathing insufficiency and eventually breathing…
- Trial name
- NCT00537446
- Testing
- noninvasive positive pressure ventilation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Columbia University
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