Clinical trials: Nutritional Deficiencies
Severe Acute Malnutrition in Childhood, Malnutrition, Child
Treatment of Severe Acute Malnutrition in Children 6 to 59 Months Old With Standard Ready To Use Therapeutic Food Compared to a Newly Formulated Lipid Optimized Ready To Use Therapeutic Food
The goal of this randomized clinical trial is to learn if a newly formulated Lipid-Optimized Ready-to-Use Therapeutic Food (LO-RUTF) can treat severe acute malnutrition in children aged 6 to 59 months.
- Conditions
- Severe Acute Malnutrition in Childhood, Malnutrition, Child, Neurocognition, Child
- Trial name
- NCT07345884
- Testing
- Lipid-Optimized Ready to Use Therapeutic Food (RUTF), Ready to Use Therapeutic Food (RUTF)
- Where
- Pakistan
- Volunteers
- 125 people
- Sponsor
- University of California, Los Angeles
Vitamin D Deficiency, Vascular Calcification
Effects of Cholecalciferol on Osteoprotegerin Levels in Patients on Peritoneal Dialysis
Aim: To investigate whether cholecalciferol (4800 U/daily) or placebo for 16 weeks reduces proteins levels associated with vascular calcification (osteoprotegerin, osteopontin, osteocalcin) in patients treated with peritoneal…
- Conditions
- Vitamin D Deficiency, Vascular Calcification, Renal Insufficiency, End Stage Renal Failure on Dialysis
- Trial name
- NCT02598635
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 58 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Amyloidosis
Phase 1 Study of GSK2315698 in Healthy Japanese Subjects
This is the first study in which GSK2315698 will be administered in Japanese population. The primary objective of the study is to investigate safety and tolerability, pharmacokinetics, and pharmacodynamics after single…
- Trial name
- NCT02953808
- Testing
- GSK2315698
- Where
- Japan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Amyotrophic Lateral Sclerosis, ALS
Open-label Study to Evaluate Safety, Tolerability and PK of BHV-0223 in ALS
Phase 1, open-label study of BHV-0223 in ALS.
- Conditions
- Amyotrophic Lateral Sclerosis, ALS, Lou Gehrig Disease, Lou Gehrig's Disease
- Trial name
- NCT03520517
- Testing
- BHV-0223
- Where
- 5 sites in United States
- Volunteers
- 22 people
- Sponsor
- Biohaven Pharmaceuticals, Inc.
Amyotrophic Lateral Sclerosis
Rho Kinase Inhibitor in Amyotrophic Lateral Sclerosis (REAL)
A Phase 2a Open-Label Preliminary Safety, Efficacy, and Biomarker Study of WP-0512 in Patients with Amyotrophic Lateral Sclerosis (ALS)
- Trial name
- REAL (NCT05218668)
- Testing
- Fasudil (WP-0512)
- Where
- 12 sites in United States, Australia
- Volunteers
- 40 people
- Sponsor
- Woolsey Pharmaceuticals
Frontotemporal Dementia
Palmitoylethanolamide Combined With Luteoline in Frontotemporal Dementia Patients. A Randomized Controlled Trial
Frontotemporal dementia (FTD) is a devastating neurodegenerative disorder. It is the second most frequent cause of presenile neurodegenerative dementia in those less than 65 years of age.
- Trial name
- PEA-FTD (NCT04489017)
- Testing
- PEA-LUT
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Severely Malnourished Infants Who Are Less Than 6 Months Old
Rehabilitation of Malnourished Infants With F-100 or Diluted F-100
Hypothesis: During rehabilitation phase of management of severe acute malnourished Bangladeshi infants less than 6 months old, rates of weight gain will be significantly more in children fed F-100 and diluted F-100 compared to…
- Trial name
- NCT01558440
- Testing
- Infant Formula, F-100, Diluted F-100
- Where
- Bangladesh
- Volunteers
- 132 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Iron-deficiency
Effect of Iron-fortified Pea Powder on Exercise Performance
Female endurance athletes are susceptible to iron deficiency and this can impact their exercise performance. This study assesses the impact of an pea protein supplement with high iron bio-availability on iron status and exercise…
- Trial name
- NCT04872140
- Testing
- Low phytate pea powder, Regular pea powder
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Anemia, Malnutrition
Acceptability of Lipid-Based Nutrient Supplements (LNS) for Women and Infants
Inadequate micronutrient intakes during pregnancy, lactation and infancy remain a major problem in Ghana. Lipid-based nutrient supplements (LNS) made using vegetable oil, groundnut paste, milk, sugar, and micronutrients may offer…
- Trial name
- NCT00970840
- Testing
- LNS-20gM or LNS-P&L
- Where
- Ghana
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Amyotrophic Lateral Sclerosis
Autologous Bone Marrow Mesenchymal Stem Cells in the Treatment of Patients With Amyotrophic Lateral Sclerosis
The goal of this study is to investigate the safety and tolerability of autologous bone marrow-derived mesenchymal stem cells administration in the individuals with diagnosed amyotrophic lateral sclerosis.
- Trial name
- UwmBmmscALS (NCT02881489)
- Testing
- Biological: Cell-based therapy
- Volunteers
- 30 people
- Sponsor
- University of Warmia and Mazury
Failure to Thrive, Nutritional Deficiency
Nasogastric Tube Securement Comparison Study
This study evaluates the use of tape to secure nasogastric tubes compared to securement with a nasal bridle device.
- Conditions
- Failure to Thrive, Nutritional Deficiency, Constipation, Bowel Obstruction
- Trial name
- NTSNB (NCT03202576)
- Testing
- Nasal Bridle
- Volunteers
- 43 people
- Sponsor
- University of Colorado, Denver
Child Malnutrition
Developing Low-Cost Universal Malnutrition Screening for Low Income Countries - the MAMMS Trial
Acute malnutrition affects 52 million children, costs $2.1 trillion globally, and contributes to 45% of deaths among children under five years of age.
- Trial name
- NCT03967015
- Testing
- Maternal Administered Malnutrition Monitoring System (MAMMS)
- Where
- 3 sites in Kenya
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Washington
Bronchial Asthma, Vitamin D Deficiency
Vitamin D Status and Asthma Control, Pulmonary Function, and Oxidative Stress in Adults With Bronchial Asthma
Asthma is a chronic inflammatory airway disease associated with variable airflow limitation and persistent respiratory symptoms.
- Conditions
- Bronchial Asthma, Vitamin D Deficiency, Pulmonary Function Impairment, Oxidative Stress
- Trial name
- VD-ASTHMA (NCT07733635)
- Volunteers
- 134 people
- Sponsor
- Sinai University
Amyotrophic Lateral Sclerosis
Open-label Clinical Trial of Lacosamide in ALS
Lacosamide is administered for patients with amyotrophic lateral sclerosis (ALS).
- Trial name
- NCT03186040
- Testing
- Lacosamide
- Where
- Japan
- Volunteers
- 7 people
- Sponsor
- Chiba University
Child Malnutrition
Parental Misperceptions on Child Nutrition in India: Implications for Child Feeding Practices and Growth
The goal of this randomized controlled trial is to examine the role of parental misperceptions and information gaps in contributing to poor child dietary practices and high child undernutrition rates in India.
- Trial name
- NCT06473025
- Testing
- Information on Relative Nutritional Status, Information on Returns to Child Nutrition
- Where
- India
- Volunteers
- 1,542 people
- Sponsor
- University of Southern California
Bacterial Pneumonia
Vitamin D Supplementation Prevents Elderly Pneumonia
Pneumonia is the fourth leading cause of death and frequently occurs in institutionalized elderly people in Japan. Recently, several clinical and experimental studies have reported the importance of vitamin D in the regulation of…
- Trial name
- NCT00877422
- Testing
- Vitamin D3
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Tohoku University
Chronic Renal Failure, Hemodialysis
Comparing the Hemodiafiltration On-line and Conventional Hemodialysis in Terms of Cost-benefit
The site where the clinical trial will be conducted is at the St-Luc hospital from the CHUM. This is a prospective randomized study that will compare the two treatment modalities, HD and HDF, through economics and…
- Trial name
- PHARMACO-$ (NCT02374372)
- Testing
- conventional hemodialysis, hemodiafiltration On-line
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Amyotrophic Lateral Sclerosis (ALS)
Masitinib in Combination With Riluzole for the Treatment of Patients Suffering From Amyotrophic Lateral Sclerosis (ALS)
The objective is to compare the efficacy and safety of masitinib in combination with riluzole in the treatment of patients suffering from Amyotrophic Lateral Sclerosis (ALS).
- Trial name
- NCT02588677
- Testing
- Masitinib (4.5), Riluzole, Masitinib (3.0)
- Where
- Spain
- Volunteers
- 394 people
- Sponsor
- AB Science
Hospital Foodservice Satisfaction; Hospital Meals Satisfaction; Elderly, Nutrition, Malnutrition in Elderly, Malnutrition
A Logical Framework for Tailor-made Paradigm Shift Hospital Foodservice to Prevent Malnutrition Among Geriatric Patients in Hospitals
Hospital Food service is important for patient recovery by providing necessary aid with adequate meal consumption. Overall, hospital experience can influence patients' satisfaction for the foodservice quality.
- Trial name
- NCT04858165
- Testing
- MY GERYFS PROTOCOL
- Where
- 5 sites in Malaysia
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Malnutrition
EnergieShake® Acceptability and Tolerance Study
This open-label, prospective, controlled intervention study involves evaluating tolerance and acceptability of an Oral Nutrition Supplement (ONS; EnergieShake®) in 16 adult patients who are already taking an ONS.
- Trial name
- NCT02788032
- Testing
- EnergieShake oral supplement
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Anaiah Healthcare Pvt Ltd
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