Clinical trials: Nutritional Deficiency in Pregnancy (Disorder)
Iron Deficiency Anaemia, Iron Deficiency Anemia
Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease
Evaluation of safety and efficacy of iron isomaltoside/ferric derisomaltose compared with iron sucrose, in subjects with both non-dialysis-dependent chronic kidney disease (NDD-CKD) and iron deficiency anaemia (IDA).
- Conditions
- Iron Deficiency Anaemia, Iron Deficiency Anemia, Chronic Kidney Disease
- Trial name
- NCT02940860
- Testing
- Iron isomaltoside/ferric derisomaltose, Iron sucrose
- Where
- 141 sites in United States
- Volunteers
- 1,538 people
- Sponsor
- Pharmacosmos A/S
Chronic Renal Disease, Iron-Deficiency Anemia
Oral Iron Supplementation for Patients With Chronic Kidney Disease
The hypothesis of this research is that oral iron prescribed in a single dose in alternate day could mitigate the side effects with regard to intestinal microbiota, inflammation, oxidative stress and improve the hematological…
- Conditions
- Chronic Renal Disease, Iron-Deficiency Anemia, Anemia of Chronic Kidney Disease, Dysbiosis
- Trial name
- NCT05544513
- Testing
- Ferrous sulfate 3 days week, Ferrous sulfate daily, Ferrous sulfate higher concentration
- Where
- Brazil
- Volunteers
- 6 people
- Sponsor
- Universidade Federal Fluminense
Asthma, Vitamin D Resistant Rickets
Assessment Of Vitamin D Role In The Pathogenesis Of Asthma In Vitamin D Resistent Patients
Research Title: Evaluation of airway reactivity, allergy and inflammatory mediators in exhaled breath condensate in vitamin D resistant rickets.
- Trial name
- NCT01578824
- Testing
- Methacholine Challenge Test
- Where
- Israel
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Iron Deficiency (Without Anemia), Pregnancy Related
Ferritin Screening And IRon Treatment for Maternal Anemia and FGR Prevention Trial
Prevalence of anemia in Asia is more than 50%. All woman who book for antenatal care with non-anaemic iron deficiency (NAID) can be offered therapeutic doses of parentral iron, as a directly observed complete therapy, to prevent…
- Trial name
- FAIR (NCT04228627)
- Testing
- Parentral Iron
- Where
- 3 sites in Pakistan
- Volunteers
- 600 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Pregnancy Related, Anemia, Iron Deficiency
Early Antenatal Support for Iron Deficiency Anemia
This is a randomized, controlled multi-site trial of iron therapy in pregnancy. The purpose of this research is to see if second trimester initiation of intravenous (IV) iron therapy is better than oral iron therapy for treatment…
- Conditions
- Pregnancy Related, Anemia, Iron Deficiency, Anemia of Pregnancy
- Trial name
- EASI-A (NCT04278651)
- Testing
- Ferumoxytol, Ferrous Sulfate
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Thomas Jefferson University
BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome, Breast Ductal Carcinoma In Situ
Identifying and Caring for Individuals With Inherited Cancer Syndrome
This trial examines approaches to identify and care for individuals with inherited cancer syndrome. The purpose of this study is to offer no cost genetic testing to the general public.
- Conditions
- BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome, Breast Ductal Carcinoma In Situ, Hematopoietic and Lymphoid System Neoplasm, Hereditary Neoplastic Syndrome
- Trial name
- NCT04494945
- Testing
- Biospecimen Collection, Genetic Counseling, Genetic Testing
- Where
- 2 sites in United States
- Volunteers
- 27,500 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Congenital Adrenal Hyperplasia
Effects and Importance of Epinephrine/Adrenalin Deficiency in CAH
Individuals with CAH produce lower levels of epinephrine (adrenalin) than controls. This can be correlated to the CYP21A2 genotype and is most pronounced in the classic forms.
- Trial name
- NCT05162950
- Testing
- physical exercise as a standardized high intensity exercise test, Stress vulnerability
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Children Over 3 Undergoing Dialysis With Secondary Hyperparathyroidism
Calcium Isotope Ratios to Assess Calcium Bone Balance in Dialysis Children Receiving Cinacalcet
Managing bone and mineral disorders associated with chronic kidney disease (CKD-MBD) in children is a complex task. Controlling parathyroid hormone (PTH) levels involves adjusting calcium intake, managing hyperphosphatemia…
- Trial name
- Cin-ca (NCT07007338)
- Testing
- Supplementary blood samples and urines samples
- Where
- 7 sites in France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Anemia, Iron Deficiency
Co-administration of Calcium and Multiple Micronutrient Supplements for Maternal and Newborn Hemoglobin and Iron Status
The World Health Organization (WHO) currently recommends the pregnant women receive iron-containing supplements and, in settings where calcium intake is low, calcium supplements.
- Trial name
- CaMMS (NCT06568315)
- Testing
- Concurrent multiple micronutrient and calcium supplementation, Separate multiple micronutrient and calcium supplementation
- Where
- 2 sites in Burkina Faso, Pakistan
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Iron Deficiency, Anemia of Prematurity
Early Versus Late Enteral Iron in Infants Less Than 1301 Grams
Background: Preterm infants are at risk of iron deficiency. The smaller the infants are at birth, the smaller the iron stores at birth and the higher the risk of iron deficiency.
- Trial name
- NCT00458068
- Testing
- Oral administration of ferrous sulphate
- Where
- Germany
- Volunteers
- 126 people
- Sponsor
- University of Ulm
Chronic Kidney Disease; Iron Deficiency Anemia
A Study to Evaluate the Safety (Compared to Iron Sucrose), Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects With Chronic Kidney Disease (CKD)
Primary Objectives: To evaluate the safety (compared to iron sucrose) and efficacy of ferumoxytol in pediatric CKD subjects with iron deficiency anemia (IDA) or who are at risk of development of IDA Secondary Objective: To…
- Trial name
- NCT03619850
- Testing
- Ferumoxytol, Iron sucrose
- Where
- 21 sites in United States, Hungary and 3 more
- Volunteers
- 129 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Congenital Adrenal Hyperplasia, Adrenal Insufficiency
Evaluation of Circadian Hormonal Balance: LC-MS/MS Measurement of Salivary and Serum Steroids in Patients With Congenital Adrenal Hyperplasia
In congenital adrenal hyperplasia (CAH), lifelong hormone replacement therapy is required to treat adrenal insufficiency and to reduce elevated androgen levels. This is essential to ensure "normal" growth and puberty.
- Conditions
- Congenital Adrenal Hyperplasia, Adrenal Insufficiency, Hyperandrogenism; 21-hydroxylase Deficiency
- Trial name
- MASSALIVE (NCT07718230)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kidney Transplantation, Vitamin D Deficiency
Vitamin D3 Substitution in Vitamin D Deficient Kidney Transplant Recipients
The purpose of the study is to evaluate the effects of Cholecalciferol (Vitamin D3) substitution on the posttransplant outcome (glomerular filtration rate as well as serum creatinine levels, number of acute rejection episodes…
- Conditions
- Kidney Transplantation, Vitamin D Deficiency, Renal Osteodystrophy
- Trial name
- VITA-D (NCT00752401)
- Testing
- Cholecalciferol
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Medical University of Vienna
Vitamin D Deficiency
Nutritional Requirements for Vitamin D in Pregnant Women
Randomised, placebo-controlled dose-response intervention study with vitamin D3 in pregnant women.
- Trial name
- DMAT (NCT02506439)
- Testing
- 10 mcg Vitamin D3, 20 mcg Vitamin D3
- Where
- 2 sites in Ireland
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University College Cork
Polycystic Ovary Syndrome, Insulin Resistance
Is There Association Between Vitamin D Levels And Insulin Resistance In Polycystic Ovary Syndrome?
The primary aim of the current study is to clarify whether serum vitamin D levels [25(OH)D3] have a temporal association with insulin resistance and/or insulin sensitivity in PCOS women versus healthy ones.
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Vitamin D Deficiency
- Trial name
- NCT02803476
- Where
- Egypt
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Vitamin D Deficiency, Pre-Eclampsia
Effect of Vitamin D3 Supplementation in Pregnancy on Risk of Pre-eclampsia
Vitamin D deficient pregnant ladies were selected and randomized into 2 groups for routine daily dose of multivitamin (400IU vitamin D3) versus maximum safest treatment daily dose (4000IU vitamin D3).
- Trial name
- NCT03101150
- Testing
- 400 IU Vitamin D3, 4000 IU Vitamin D3
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Iron Deficiency Anemia of Pregnancy
Daily vs Intermittent Iron Therapy in Pregnancy
This is a randomized non inferiority trial to evaluate the response to iron therapy in the standard daily vs. intermittent (three-four times a week on nonconsecutive days) groups by using hematological markers (hemoglobin…
- Trial name
- NCT03706638
- Testing
- Ferrous Sulfate
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- UConn Health
Rare Diseases, X-linked Hypophosphatemia
Burosumab in Children and Adolescents With X-linked Hypophosphatemia
In this prospective longitudinal cohort study we studied the efficacy and safety of burosumab in real-clinical practice for <13- and >13-years old children affected with X-linked hypophosphatemia.
- Trial name
- NCT04419363
- Testing
- Burosumab Injection
- Where
- France
- Volunteers
- 57 people
- Sponsor
- Bicetre Hospital
Malnutrition
Dose Comparison of Amino Acids on Growth in Premature Neonates
Malnutrition is a common problem in the neonatal intensive care unit. Recent studies indicate that prematurely born neonates commonly develop a severe nutritional deficit during the first weeks after birth, referred to as…
- Trial name
- NCT00120926
- Testing
- Parenteral Nutrition
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Pediatrix
Secondary Hyperparathyroidism
Open-label Study to Assess the Long-term Safety and Efficacy of Etelcalcetide (Also Known as AMG 416 or KAI-4169) in Patients With Secondary Hyperparathyroidism
The purpose of this study is to evaluate the long term safety and efficacy of thrice weekly intravenous (IV) administration of etelcalcetide in the treatment of secondary hyperparathyroidism (SHPT) in patients receiving…
- Trial name
- NCT01576146
- Testing
- Etelcalcetide
- Volunteers
- 30 people
- Sponsor
- KAI Pharmaceuticals