Clinical trials: Nutritional Supplement
Total Knee Replacement
A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation
We are going to evaluate the difference between perioperative intravenous steroid supplementation, perioperative periarticular steroid supplementation, and standard anaesthesia protocols.
- Trial name
- NCT04432012
- Testing
- Dexamethasone Sodium Phosphate 4 mg/ml intravenous, Dexamethasone Sodium Phosphate 4 mg/ml intra-articular
- Where
- Switzerland
- Volunteers
- 159 people
- Sponsor
- Christian Candrian
Critical Limb Ischemia, Malnutrition
Nutrition in Patient With Critical Limb Ischemia
A prospective pilot study examining nutritional supplements among vascular surgery patients with Critical Limb Ischemia (CLI). CLI patients have a high rate of malnutrition and has the potential to benefit greatly from…
- Conditions
- Critical Limb Ischemia, Malnutrition, Nutritional Supplements
- Trial name
- NutriVasc (NCT03529019)
- Testing
- Ensure Surgery Immunonutrition Shake, Ensure Enlive Advanced Nutrition Shake
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston Medical Center
Mental Processes
The Effects of Flavonoid Supplementation on Cognition and Neural Mechanisms in Healthy Older Adults
A double-blind, randomised, controlled, parallel arm chronic intervention trial with healthy older adults will be conducted to determine the effect of a flavonoid-rich supplement on cognitive function, peripheral arterial health…
- Trial name
- CoCo_Chronic (NCT03030053)
- Testing
- Cocoa-Flavanol Supplements, Control Supplements
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Reading
Vitamin D Deficiency
Bioavailability of Vitamin D Encapsulated in Casein Micelles, Compared to Its Bioavailability in a Synthetic Emulsifier Currently Used for Supplementation and Enrichment.
Background: Vitamin D3 (VD) is an oil soluble vitamin formed in the skin during exposure to UV light. It is essential for bone and calcium metabolism, insulin reactivity, immune system etc.
- Trial name
- VD (NCT01807845)
- Testing
- enriched skimmilk with VD, Skimmilk enriched with VD wherein the VD will be emulsified using Tween 80
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Healthy Adults Reporting Recurrent Gastrointestinal Symptoms
A Real-world Study of Gastrointestinal Health and Mental Wellness in U.S. Adults Following 12 Weeks of Probiotic Supplementation.
This real-world study conducted in the U.S.A aims to understand how gastrointestinal (GI) symptoms and wellbeing, including mood, sleep, and eating behaviours, change over time in 300 adults who choose to take a probiotic dietary…
- Trial name
- NCT07849036
- Testing
- Probiotic
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Novonesis
Infection, Pregnancy
Effects of Oral Probiotic Supplementation on Group B Strep (GBS) Rectovaginal Colonization in Pregnancy
The investigators wish to determine if oral probiotic supplementation during the second half of pregnancy decreases maternal GBS recto-vaginal colonization at 35-37 weeks' gestational age, thereby decreasing need for maternal…
- Trial name
- NCT01479478
- Testing
- Probiotic dietary supplement
- Where
- 3 sites in United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Stanford University
Healthy
Indole-3-PROpionic Acid Clinical Trials - a Pilot Study
The goal of this pilot intervention trial is to investigate the biological effects of daily supplementation with different doses of indole-3-propionic acid (IPA) in healthy adults.
- Trial name
- iPROACT-pilot (NCT06674018)
- Testing
- Indole-3-propionic acid
- Where
- Denmark
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
HIV, AIDS
Zinc Supplementation Effect on Immune Recovery in HIV Patients
INTRODUCTION: An adequate zinc supplementation is essential for a good immunological function. However, zinc deficiency is seen in more than 50% of adults infected with HIV.
- Conditions
- HIV, AIDS, Immunological Deficiency, Inadequate Immune Recovery
- Trial name
- NCT02162797
- Testing
- Zinc supplementation
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CES University
COPD (Chronic Obstructive Pulmonary Disease), Probiotic Intervention
Probiotics in Pulmonaty Rehabilitation for COPD
This study aims to investigate various aspects of patients with chronic respiratory diseases undergoing pulmonary rehabilitation supplemented with probiotics.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Probiotic Intervention, Body Composition Measurement
- Trial name
- NCT06717659
- Testing
- probiotic supplementation intervention, standard pulmonnary rehabilitation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Fu Jen Catholic University
Nitrate, Placebo - Control
Beetroot Juice and Neuromuscular Performance in Female Basketball Players
A randomized, double-blind, placebo-controlled study investigates the effects of 5 days of nitrate-rich beetroot juice supplementation (70 mL·day-¹; 6.4 mmol NO₃-·day-¹) on physical performance in female basketball players.
- Trial name
- BASKET_BEET (NCT07833579)
- Testing
- Beetroot juice supplementation
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad Pontificia Comillas
Perimenopausal Disorder
Effects of a Standardised Saffron Extract Supplementation on Symptoms Associated With Perimenopause in Healthy Women
The aim of the present study is to assess the effects of a normalised saffron extract supplementation, which is an extract of the flower Crocus sativus, on perimenopausal symptoms.
- Trial name
- NCT06227858
- Testing
- Safr'Inside supplement (Activ'Inside, SAS), Plcebo
- Where
- Pakistan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Implant Site Reaction
Perioperative Oral Vitamin D3 Supplementation on Implant Osseointegration
The number of patients treated in Implantology at Nantes University Hospital is 400 per year. This pilot study aims to demonstrate the efficacy of a 6-month oral cholecalciferol supplementation on osseointegration in patients…
- Trial name
- OSIVID (NCT06776640)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Nantes University Hospital
Temporomandibular Disorder (TMD)
Marine Lipids Ease Painful TMD
The ADAPT study is a single-site, Phase 2b, randomized, quadruple-masked, placebo-controlled trial evaluating an omega-3 dietary supplement enriched with specialized pro-resolving mediator (SPM) precursors in adults with chronic…
- Trial name
- ADAPT (NCT07437313)
- Testing
- SPM Precursor-Enriched Marine Lipid Supplement, Medium-Chain Triglyceride Supplement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Infant Gut Microbiome
The EFFECT Study: Probiotic and HMO Supplementation in Infants
Lacto-N-tetraose (LNT) is a human milk oligosaccharide (HMO) present in human colostrum and milk. HMOs are largely undigestable and have no direct nutritive benefit to the infant, but act as a prebiotic substrate for beneficial…
- Trial name
- EFFECT (NCT03994315)
- Testing
- B. infantis EVC001, Lacto-N-tetraose (LNT)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Evolve BioSystems, Inc.
Functional Gastrointestinal Disorders, Functional Abdominal Pain
Effect of 35624® Alflorex® in Functional Gastrointestinal Disorders (FGIDs) in Children.
The aim of this study is to evaluate the effect of supplementation with Bifidobacterium longum 35624® Alflorex® on frequency and severity of symptoms of abdominal pain using an adapted Irritable Bowel Symptom Severity Scoring…
- Trial name
- NCT04922476
- Testing
- Alflorex®
- Where
- Chile
- Volunteers
- 65 people
- Sponsor
- PrecisionBiotics Group Ltd.
Protein-energy; Imbalance, Recovery
Pre-sleep Protein Supplementation in British Army Recruits
Dietary protein has been shown to be important to support physical training. For occupational demands such as military training, new recruits often fail to meet the recommended protein intake during basic training (BT), with…
- Conditions
- Protein-energy; Imbalance, Recovery, Body Weight
- Trial name
- NCT05998590
- Testing
- High protein supplement, Moderate protein supplement, Control: No supplementation
- Where
- United Kingdom
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Anglia Ruskin University
Vitamin D Deficiency, Cystic Fibrosis
Efficacy of Intensive Cholecalciferol Monitoring and Supplementation on Serum vitD Levels in Pediatric Patients With CF
Cystic fibrosis (CF) is an autosomal recessive disease caused by alterations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, characterized by multisystemic alterations, mainly in the lung, intestine…
- Conditions
- Vitamin D Deficiency, Cystic Fibrosis, Bone Density, Low, Inflammation Chronic
- Trial name
- NCT05276960
- Testing
- Cholecalciferol Pill
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Sarcopenia
Dietary Supplements and Aging Muscle
The purpose of this study is to determine whether older adults (ages 65-89) who consume the dietary supplement Juven (Abbott Laboratories) versus placebo for 6 months will demonstrate increases in fat-free mass, muscle volume,and…
- Trial name
- NCT01057082
- Testing
- Juven
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Alzheimer Disease and Related Dementias (ADRD)
Veech Ketone Ester to Support Brain Energy in Mild Cognitive Impairment and Early Alzheimer's Disease
It is projected that by 2030, one in every five Americans will be of retirement age, and this demographic shift is expected to result in more people suffering from dementia.
- Trial name
- NCT06767124
- Testing
- Ketogenic Supplement
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- University of Pennsylvania
Overweight, Metabolic Syndrome X
Impact of Chromium, Phyllanthus Emblica, and Shilajit on Cardiovascular Health, Fitness, and Weight Loss During Exercise and Diet Programs
A randomized, double-blind, placebo controlled, parallel study to determine if Chromium (Cr), Phyllanthus emblica (PE) and Shilajit (SJ) supplementation and Phyllanthus emblica fruit extract supplementation promotes greater…
- Trial name
- NCT06641596
- Testing
- Cr-400, Cr-800, PE-500
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Kerry Group P.L.C
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.