Clinical trials: Nutritional Wasting
Breast Cancer, Cachexia
Effect of Dietary Counseling and Nutritional Monitoring in Reducing Cancer-related Cachexia Among Female Oncology Patients
In this parallel, two-arm randomized controlled trial (RCT), 140 female patients with advanced-stage breast cancer and clinical features of cachexia will be randomized using block-stratified allocation into an intervention group…
- Trial name
- NCT07112482
- Testing
- Standard Oncological Care + Tailored Dietary Counseling + Nutritional Monitoring
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Pakistan Society of Pediatric Oncology
Malnutrition, Gastroenterostomy
Washed Microbiota Transplantation for Malnutrition After Nonphysiological Reconstruction of the Upper Gastrointestinal Tract
This is a prospective, randomized, multicenter study to evaluate WMT in improving nutritional status in malnourished patients who underwent nonphysiological reconstruction of the upper gastrointestinal tract.
- Trial name
- NCT05439135
- Testing
- washed microbiota transplantation
- Where
- China
- Volunteers
- 62 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Severe Acute Malnutrition, Wasting
A Novel Low-Cost Tool for a More Efficient and Reliable Weight-for-Height/Length Assessment
Weight-for-height/length z-score is one of the indicators used to diagnose acute malnutrition. In the existing method, the assessment involves three steps and takes significant time with a wider room for errors.
- Trial name
- Yared's-tool (NCT03780348)
- Testing
- New Method, Existing Method
- Volunteers
- 510 people
- Sponsor
- JSI Research & Training Institute, Inc.
Wasting, Moderate Acute Malnutrition
Effectiveness of Nutritional Products to Treat Moderate Acute Malnutrition
The purpose of this study is to determine whether an improved corn-soya blend (CSB+) and a new formulated ready-to-use supplementary food (RUSF) are effective in the treatment of moderate acute malnutrition in children.
- Trial name
- NCT01898871
- Testing
- A daily ration of 40 kcal/kg of body weight during 56 days
- Where
- 2 sites in Cameroon
- Volunteers
- 81 people
- Sponsor
- Centre for Food and Nutrition Research, Yaounde
HIV Infections, HIV Wasting Syndrome
The Effect of Anti-HIV Treatment on Body Characteristics of HIV-Infected Children
The purpose of this study is to see how beginning or changing anti-HIV medications affects the body composition (weight, height, growth, body fat, and muscle mass, or fat and muscle distribution) of HIV-infected children.
- Conditions
- HIV Infections, HIV Wasting Syndrome, Lipodystrophy
- Trial name
- NCT00006064
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Military Operational Stress Reaction, Malnutrition (Calorie)
Effects of Protein Supplementation on Lean Body Mass Recovery From Extreme Military Training
The purpose of this study is to evaluate the physiological consequences of extreme military training and determine whether protein supplementation enhances recovery by promoting gains in lean body mass.
- Conditions
- Military Operational Stress Reaction, Malnutrition (Calorie), Weight Loss, Muscle Wasting
- Trial name
- NCT02057094
- Testing
- Protein, High-Protein, and Control
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
HIV, Pregnancy
Maternal Determinants of HIV-exposed and HIV-unexposed Fetal Growth, Birth Outcomes and Early Infant Growth
The purpose of this study is to understand how differences in the nutritional status and concentration of hormones and cytokines associated with cachexia in HIV+ and HIV- pregnant women living in a semi-rural and rural region of…
- Conditions
- HIV, Pregnancy, Malnutrition, Cachexia
- Trial name
- NCT01647841
- Where
- Tanzania
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Cornell University
Malnutrition, Infant, Malnutrition, Child
Efficacy of Mobile Health Application in Promotion of Exclusive Breast Feeding and Young Child Feeding Practices in Pakistan
Early life nutrition is the key modifiable determinant of child growth, development, survival and diseases of adult onset. Pakistan ranks highest for neonatal mortality rate (44.2/1000 live births (LBs)) globally.
- Trial name
- NCT05590351
- Testing
- First diet: m-health coaching application, Face to Face counselling
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Electrolyte Disturbances, Subarachnoid Hemorrhage
Electrolyte and Fluid Disturbances in Subarachnoid Hemorrhage and Traumatic Brain Injury
During the course of their acute illness patients with subarachnoid hemorrhage and severe traumatic brain injury often develop disturbances in their fluid balance and electrolyte homeostasis.
- Conditions
- Electrolyte Disturbances, Subarachnoid Hemorrhage, Traumatic Brain Injury, Natriuretic Peptides
- Trial name
- NCT01313975
- Where
- Switzerland
- Volunteers
- 85 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Old Age; Cachexia, Dietary Habits
The Nutritionist's Educational Intervention on the Protein Intake in Hospitalized Elderly People
The food intake is often compromised in the elderly, and during hospitalization, dietary restrictions may be imposed, making them more susceptible to the risk of malnutrition and sarcopenia.
- Conditions
- Old Age; Cachexia, Dietary Habits, Sarcopenia, Protein Malnutrition
- Trial name
- NCT05502445
- Testing
- educational intervention
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Hospital Israelita Albert Einstein
Cerebral Hyponatremia, SIADH
Fractional Urate Excretion in Nonedematous Hyponatremia
Hyponatremia, defined as a serum sodium < 135 mmol/l, in patients without edema has undergone significant changes where it is now evident that even mild hyponatremia should be treated because of its association with symptoms…
- Conditions
- Cerebral Hyponatremia, SIADH, Cerebral Salt-wasting Syndrome, Reset Hypothalamic Osmostat
- Trial name
- NCT01425125
- Testing
- Tolvaptan in euvolemic hyponatremia
- Where
- United States
- Sponsor
- NYU Langone Health
Critical Illness, Intensive Care (ICU) Myopathy
Early Goal-Directed Nutrition in ICU Patients - EAT-ICU Trial
An increasing number of patients survive critical illness and intensive care, but describe having impaired physical function several years after discharge as a consequence of extensive loss of muscle mass.
- Conditions
- Critical Illness, Intensive Care (ICU) Myopathy, Muscle Wasting, Loss of Physical Function
- Trial name
- EAT-ICU (NCT01372176)
- Testing
- Early Goal-Directed Nutrition, ASPEN-guidelines
- Where
- Denmark
- Volunteers
- 203 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cachexia, Cancer
Safety, Tolerance and Efficacy of an Oral Nutritional Supplement in Lung Cancer Patients
To test the compliance, tolerance, safety and to get preliminary insights into the efficacy of a new oral nutritional supplement (containing n-3 fatty acids, amino acids and antioxidants) designed to prevent or delay cachexia and…
- Trial name
- NCT00851448
- Testing
- oral nutritional supplement, food for special medical purposes
- Where
- 3 sites in Italy, Poland
- Volunteers
- 17 people
- Sponsor
- Fresenius Kabi
HIV Infections, HIV Wasting Syndrome
A Study to Evaluate High Protein Supplementation in HIV-Positive Patients With Stable Weight Loss
The purpose of this study is to determine whether a high-quality protein food supplement will help HIV-positive patients maintain, and possibly gain, muscle mass.
- Trial name
- NCT00000925
- Testing
- Optimune oral nutritional supplement
- Where
- 19 sites in United States, Puerto Rico
- Volunteers
- 56 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pancreatic Carcinoma
L-CARnitine in the Palliative Treatment of Advanced PANcreatic Cancer (CARPAN)
The study investigated the role of L-Carnitine supplementation on proinflammatory immune response, malnutrition, cancer cachexia and cancer related fatigue in advanced and inoperable pancreatic cancer, UICC Stage IV .
- Trial name
- CARPAN (NCT01330823)
- Testing
- L-Carnitine
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- University Medicine Greifswald
Stunting, Wasting
Weight Patterns in the Month After Birth
This is a prospective cohort study that will be conducted in four low income countries to describe newborn weight patterns in the first month after birth and their association with clinical and demographic factors including…
- Conditions
- Stunting, Wasting, Undernutrition, Feeding Patterns
- Trial name
- NCT04025827
- Testing
- Dietary intake
- Where
- 5 sites in United States, Guinea-Bissau and 3 more
- Volunteers
- 741 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Undernutrition, Underweight
Satiation Study With Children Attending a Tertiary Feeding Clinic
This is a pilot study of children attending the Glasgow feeding clinic (GFC) which looks after children with severe feeding problems who commonly have low appetite and extreme thinness.
- Trial name
- NCT04851327
- Testing
- High Energy preload, Low energy preload, Test meal
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Glasgow
Malnutrition, Stunting
Child Health, Nutrition and Microbiome Development
Childhood malnutrition is a global public health issue with devastating consequences on the health, well-being, and psychosocial development of children.
- Conditions
- Malnutrition, Stunting, Wasting, Underweight
- Trial name
- CHAMP (NCT05793294)
- Where
- 2 sites in Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Obesity, Bariatric Surgery
Protein Need and Interest of " Quick Proteins " to the Obese Subject Operated by Bariatric Surgery (BIBOP)
The main objective of the study is to evaluate the protein requirement associated with postoperative weight loss caused by by-pass (shunt which leads to a certain degree of malabsorption) or sleeve gastrectomy (more technically…
- Trial name
- BIBOP (NCT01249326)
- Testing
- bariatric surgery
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Kidney Hospitalized
Wasting in Chronic Kidney Disease
Protein energy wasting is an independent factor associated with morbi-mortality in chronic kidney disease. Wasting is particularly common in chronic diseases of organs such as kidney disease with a major impact at the stage of…
- Trial name
- PEW (NCT03135717)
- Testing
- Nutritional care
- Volunteers
- 48 people
- Sponsor
- Hospices Civils de Lyon