Clinical trials: OAT
Celiac Disease, Gluten Sensitivity
RCT: Effect of Late vs Early Introduction of Gluten-free Oats on Patients With Newly Diagnosed Celiac Disease.
The investigators are conducting a pilot study to investigate the impact of late compared to early introduction of gluten-free oats on gut symptoms, nutrition status, celiac activity and quality of life in patients with a recent…
- Conditions
- Celiac Disease, Gluten Sensitivity, Gluten Allergy, Gluten Enteropathy
- Trial name
- NCT05803408
- Testing
- gluten-free oats
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Normoglycemic, Normal Body Weight
A Study of the Effect of Oats on Post Prandial Glucose Response
The objectives are to assess the effects of high viscosity vs. medium and low viscosity oat β-glucan on post-prandial glycemic response in healthy adult participants.
- Trial name
- NCT02651597
- Testing
- Oatmeal
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Malnutrition; Diabetes, Malnutrition; Protein
Impact of Pea, Lentil and Oat Flour Particle Size on Glycemic Response in Healthy Adults
The study looks at the comparative effects of food products made with pea, lentil, and oat flour of various particle sizes on postprandial glycemic response, appetite and food intake, and amino acid release in healthy adults.
- Conditions
- Malnutrition; Diabetes, Malnutrition; Protein, Obesity
- Trial name
- PLO (NCT05291351)
- Testing
- Crackers made with whole, coarse, or fine pea and/or wheat flour, Crackers made with whole, coarse, or fine lentil and/or wheat flour, Porridge made with oat flour
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Rheumatoid Arthritis
DF(Oat Bran) Intervention on Inflammation, Intestinal Flora, Disease Activity and Quality of Life in Patients With RA
The goal of this clinical trial is to test in Rheumatoid arthritis. The main question it aims to answer are: To verify the effect of dietary fiber supplementation on reducing the level of inflammation; To verify the effect of…
- Trial name
- NCT06322784
- Testing
- Oat bran (dietary fiber)
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Shenzhen People's Hospital
Peripheral Vascular Diseases, Peripheral Arterial Disease
Investigation of the Perfusion of Gluteal Muscle in Patients With Intermittent Gluteal Claudication by Non-invasive MSOT
The objective of the proposed study is to define independent parameters for the diagnostic assessment of the perfusion situation of the gluteal muscle based on multispectral optoacoustic tomography (MSOT) in patients with gluteal…
- Conditions
- Peripheral Vascular Diseases, Peripheral Arterial Disease, Intermittent Claudication, Gluteal Claudication
- Trial name
- NCT06391346
- Testing
- MSOT
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Ulrich Rother
Celiac Disease
Safety and Tolerability of Oat Containing Gluten-free Diet
The purpose of this study is to determine the safety and tolerability of oats in gluten free diet.
- Trial name
- SafeOatDiet (NCT02612766)
- Testing
- Pure, uncontaminated oats
- Where
- Romania
- Volunteers
- 25 people
- Sponsor
- Alfred Rusescu Institute for Mother and Child Care
Small Cell Lung Carcinoma Extensive Disease
Durvalumab ± Tremelimumab in Combination With Platinum Based Chemotherapy in Untreated Extensive-Stage Small Cell Lung Cancer (CASPIAN)
This is a phase III, randomized, open-label, multicenter, global study to determine the efficacy and safety of combining durvalumab ± tremelimumab with platinum based chemotherapy (EP) followed by durvalumab ± tremelimumab…
- Trial name
- CASPIAN (NCT03043872)
- Testing
- Durvalumab, Tremelimumab, Carboplatin
- Where
- 207 sites in United States, Argentina and 21 more
- Volunteers
- 987 people
- Sponsor
- AstraZeneca
Crohn's Disease, Ulcerative Colitis
Non Invasive Characterization of Pediatric Inflammatory Bowel Diseases Using Multispectral Optoacoustic Tomography
Monocentric, prospective observational study to assess bowel inflammation in children with chronic inflammatory bowel disease (IBD) using multispectral optoacoustic tomography (MSOT).
- Conditions
- Crohn's Disease, Ulcerative Colitis, IBD
- Trial name
- PED_MSOT_IBD (NCT04650867)
- Testing
- Multispectral Optoacoustic Tomography (MSOT)
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Lactose Intolerance
MSOT for Assessment of Intestinal Transit Time in Lactose Intolerance Patients
The study aims to investigate gastrointestinal transit using multispectral optoacoustic tomography (MSOT) in a prospective diagnostic study involving patients suspected of primary or secondary lactose intolerance.
- Trial name
- NCT06617364
- Testing
- gastrointestinal transit time measurement using MSOT and ICG contrast agent
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Iron Absorption
Iron Bioavailability of Fortified Oat Drink
This study will follow a double blinded randomized controlled study design to enroll 20 apparently healthy 6 year old children. The children will be fed with two different nutrient fortified oat drinks labeled with stable…
- Trial name
- NCT01423162
- Testing
- Dietary Intervention (with Vit C then without Vit C), Dietary Intervention (without Vit C followed by with Vit C)
- Where
- Philippines
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Human Health, Polyphenols
Avenanthramide and Saponin Bioavailability in Oat Bran
Avenanthramides and saponins are types of chemical compounds found naturally in oats. Avenanthramides have anti-oxidant properties, anti-atherosclerotic, anti-inflammation, and anti-proliferative effects on cancer cells in vitro.
- Conditions
- Human Health, Polyphenols, Pharmacokinetics
- Trial name
- NCT04335435
- Testing
- Oat Bran Consumption
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- North Carolina Agriculture & Technical State University
Coronary Arterial Disease (CAD)
Oat Bran and Plasma Lipid and Fecal Bacteria in Coronary Artery Disease Patients
The development of atherosclerosis is significantly influenced by the interplay between lipid and inflammatory factors. Endotoxemia, defined as the presence of endotoxins, particularly lipopolysaccharides (LPS) derived from…
- Trial name
- NCT06747234
- Testing
- Oat bran group, Control (Standard treatment)
- Where
- 2 sites in Iran
- Volunteers
- 32 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Hypoglycemia, Hyperglycemia
Influence of Dietary Fiber-rich Meals on Gene Expression and Postprandial Glucose and Lipid Response
The aim of this study is to Measure the effect on gene expression in leukocytes from a meal rich in oat bran Investigate the postprandial glucose, insulin and triglyceride responses after intake of meals containing fiber from…
- Trial name
- NCT01005342
- Testing
- Oat bran, Spray-dried oat drink, Rye bran
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Lund University
Type2 Diabetes
Oat Beta-glucan as a Supplement in Chilean Type 2 Diabetics
Objective: To evaluate the effect of oat β-glucans on the satiety perception, metabolic control and intestinal microbiota of type 2 diabetics from Talca, Chile.
- Trial name
- NCT04299763
- Testing
- Oat Beta-glucan as a Supplement in Type 2 Diabetics
- Where
- Chile
- Volunteers
- 37 people
- Sponsor
- Centro de Estudios en Alimentación y Nutrición, Chile
Unidentified Gastrointestinal Symptoms Following Gluten-free Oats Consumption
Gluten-free Oats and Gastrointestinal Health in Coeliac Disease, Part 2
The research aims to investigate the effects of gluten-free oats to the gastrointestinal health in celiac disease patients and healthy subjects.
- Trial name
- NCT02761785
- Where
- Finland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Turku
Feasibility Study for Thyroid Indication
"Clinical Evaluation of Opto-Acoustic Tomography for Detection and Diagnostic Differentiation of Thyroid Nodules"
Thyroid Feasibility Study
- Trial name
- NCT03032198
- Testing
- Imagio OA/US
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Seno Medical Instruments Inc.
Healthy
Effect of Extruded Cereals Enriched With β-glucan on Postprandial Plasma Glucose and Serum Insulin Responses
β-glucan (BG) is a viscous dietary fiber present in barley and oats that, when added to carbohydrate containing foods, reduces the postprandial glycemic response (PPGR), which is considered to be beneficial to health.
- Trial name
- NCT05556837
- Testing
- Control Cereal, OBG Cereal, BBG Cereal
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Male Infertility With OAT
Evaluating Traditional Medicine Syndromes in Male Infertility With Oligoasthenoteratozoospermia
The goal of this observational study is to identify and evaluate the characteristics of Traditional Medicine (TM) syndromes in men aged 18 to 60 with male infertility and oligoasthenoteratozoospermia (OAT) syndrome.
- Trial name
- NCT07529288
- Where
- Vietnam
- Volunteers
- 316 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Arthritis, Rheumatoid
Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis
The purpose of this feasibility study is to determine if a new emerging technology called photoacoustic tomography (PAT) can be adapted for use in humans for the detection of chronic rheumatoid arthritis.
- Trial name
- NCT00748254
- Testing
- Laser Based Photoacoustic Tomography, MRI, Ultrasound
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Small-Cell Lung Cancer
Study of AZD2811 + Durvalumab in ES-SCLC
A Phase II Multicenter, Open-Label, Single Arm Study to Determine the Efficacy, Safety and Tolerability of AZD2811 and Durvalumab Combination as Maintenance Therapy After Induction with Platinum-Based Chemotherapy Combined with…
- Trial name
- TAZMAN (NCT04745689)
- Testing
- Durvalumab, AZD2811, Carboplatin
- Where
- 12 sites in United States, Poland and 2 more
- Volunteers
- 31 people
- Sponsor
- AstraZeneca