Clinical trials: OAT
Metabolic Syndrome
Impacts of Fermented Oat-based Product on Gut Microbiota and Health
This study aims to investigate the effects of consuming fermented oat-based products on gut and overall human health. It is a randomized, controlled, cross-over trial with a dietary intervention.
- Trial name
- NCT06393114
- Testing
- Fermented oat-based product, Unfermented oat-based product
- Where
- Finland
- Volunteers
- 57 people
- Sponsor
- University of Eastern Finland
Hypertriglyceridemia, Obesity
Impact of Beans and Oats Snack Bar on Hypertriglyceridemic Women
Hypertriglyceridemia is a serious condition in the Mexican population and it is considered a major risk factor for cardiovascular disease.
- Trial name
- NCT04966494
- Testing
- BOSB
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Queretaro
Peripheral Vascular Diseases, Peripheral Arterial Disease
Calf Muscle Perfusion in Patients With Intermittent Claudication by Non-invasive MSOT
The objective of the proposed study is to define independent parameters for the diagnostic assessment of the perfusion situation of the calf muscle based on multispectral optoacoustic tomography (MSOT) in a cross-sectional…
- Conditions
- Peripheral Vascular Diseases, Peripheral Arterial Disease, Intermittent Claudication
- Trial name
- MSOT_IC (NCT05373927)
- Testing
- Multispectral Optoacoustic Tomography (MSOT)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ulrich Rother
Digestive Health, Metabolic Health
Investigating the Tolerability of Oat Fiber (BG-OS) in Healthy Individuals
The goal of this interventional study is to evaluate the tolerability and potential health benefits of oat fiber oligosaccharide (BG-OS) in healthy adults aged 18-70 years.
- Trial name
- NCT06739941
- Testing
- Oat fiber (BG-OS)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- One Bio Inc.
IBS - Irritable Bowel Syndrome
Effect of Postbiotic Product on Colonic Barriers in IBS
Impaired intestinal permeability and microbial dysbiosis are important pathophysiological mechanisms underlying irritable bowel syndrome (IBS).
- Trial name
- NCT05475314
- Testing
- ReFerm(R)
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Nordisk Rebalance A/S
Diabetic Gastroparesis
Contrast-enhanced Multispectral Optoacoustic Tomography for Non-invasive Assessment of Diabetic Gastroparesis
The objective of the proposed study is to assess gastric emptying time (GET) based on contrast-enhanced multispectral optoacoustic imaging (CE-MSOT) in a collective of patients with type 1 diabetes mellitus (T1DM).
- Trial name
- TRANSPARENT (NCT05935852)
- Testing
- Multispectral Optoacoustic Tomography (MSOT)
- Volunteers
- 40 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
High Cholesterol/Hyperlipidemia, High Blood Pressure
OAT-GUT-BRAIN: Effects of Oats and Rice on Comprehensive Health of Metabolically Challenged Individuals
The overall objective of this research entity is to reveal the comprehensive health impact of oats in metabolically challenged individuals in a 6-week intervention, compared to that of rice.
- Conditions
- High Cholesterol/Hyperlipidemia, High Blood Pressure, Overweight and Obesity
- Trial name
- NCT05526092
- Testing
- Dietary intervention, Postprandial meal test
- Where
- 2 sites in Finland
- Volunteers
- 72 people
- Sponsor
- University of Turku
Healthy
Effect of 12-week Probiotic Consumption Immobilized on Oat Flakes on Blood and Urine Biomarkers and Human Microbiome
The purpose of this clinical trial was to evaluate the effects Lactococcus cremoris spp. im-mobilized on oat flakes on human microbiome and blood and urine biomarkers of associated with human health.
- Trial name
- FOODBIOMES CT2 (NCT06293859)
- Testing
- Probiotic oat flakes, Conventional oat flakes
- Where
- Greece
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of the Aegean
Cardiovascular Diseases, Coronary Heart Disease
Meta-analysis of Oat Fiber and Cardiovascular Risk Reduction
Oat fibre has been shown to lower cholesterol and may have cardioprotective effects. However, whether this translates to actual cardiovascular risk reduction is unclear, as there is a lack of controlled human trials.
- Trial name
- NCT05171283
- Testing
- Oats or Oat Fibre
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
Clinical Assessment of Barley and Oat Phytochemicals
The goal of this placebo-controlled, 3-way crossover study is to determine the acute (24-h) bioavailability and pharmacokinetics of the major phytochemicals found whole barley and oats, as well as their effects on selected…
- Trial name
- NCT01303562
- Testing
- Whole grain oats and barley
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Tufts University
Male Infertility With OAT
Evaluating Traditional Medicine Syndromes in Male Infertility With Oligoasthenoteratozoospermia
The goal of this observational study is to identify and evaluate the characteristics of Traditional Medicine (TM) syndromes in men aged 18 to 60 with male infertility and oligoasthenoteratozoospermia (OAT) syndrome.
- Trial name
- NCT07529288
- Where
- Vietnam
- Volunteers
- 316 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
HIV - Human Immunodeficiency Virus
HIV Prevention With PrEP Among People on Opioid Replacement Therapy
The purpose of this study is to assess the feasibility and acceptability of providing oral pre-exposure prophylaxis (PrEP) and opioid agonist therapy (OAT) simultaneously in existing pharmacy-based programs operating in Alberta…
- Trial name
- OAT-PrEP (NCT07160075)
- Testing
- Simultaneous administration of OAT and oral PrEP at existing pharmacy-based programs
- Where
- 6 sites in Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cara Spence
Gyrate Atrophy
Gene Therapy for Gyrate Atrophy
This study will evaluate the safety and effectiveness of gene therapy for patients with gyrate atrophy, an inherited condition in which areas of the retina-the inner lining of the wall of the eye-become thin.
- Trial name
- NCT00001735
- Testing
- Gene therapy
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Eye Institute (NEI)
Gastrointestinal Motility
Contrast-enhanced Multispectral Optoacoustic Tomography for Functional Assessment of the Gastrointestinal Transit
This clinical trial aims to characterize a novel method of imaging the gastrointestinal tract in healthy subjects. The method is using laser-light and soundwaves and it is performed in a similar manner as conventional ultrasound.
- Trial name
- NCT05933096
- Testing
- Contrast-enhanced multispectral optoacoustic tomography
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Subjective Appetite and Satiety, Subjective Energy Levels
Oat Breakfast Satiety Study
This study is designed to test the hypothesis that on an equivalent calorie basis, oat based breakfast cereals do not provide the same satiety benefit.
- Trial name
- NCT01372683
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Plant-based Milk, Iodine Nutrition Status
The Difference in Health Outcomes After Drinking Cow's Milk Compared to Oat Milk - a Pilot Randomized Controlled Study
A new dietary trend is switching from cow\'s milk to plant-based milk alternatives, driven by the belief that this switch is beneficial for health reasons in addition to the sustainability aspect of a plant-based diet.
- Conditions
- Plant-based Milk, Iodine Nutrition Status, Lipids
- Trial name
- NCT06764173
- Testing
- Oat drink, Cow's milk
- Where
- Norway
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Healthy
Millets and Oats MRI
Breakfast porridges made from milled grains are commonly eaten worldwide. Traditionally different grains are used in different countries.
- Trial name
- MOM (NCT03068039)
- Testing
- Oats breakfast porridge, Pearl (bajra) breakfast porridge
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Platinum Refractory Extensive-Stage Small Cell Lung Carcinoma
A Phase II, Study to Determine the Preliminary Efficacy of Novel Combinations of Treatment in Patients With Platinum Refractory Extensive-Stage Small-Cell Lung Cancer
Study design This is a Phase II, open-label, multi-drug, multi-center, multi-arm, signal-searching study in patients with extensive-stage small-cell lung cancer (SCLC) who have refractory or resistant disease from prior…
- Trial name
- NCT02937818
- Testing
- Durvalumab and Tremelimumab, AZD1775 and carboplatin (CBPT), AZD6738 and olaparib
- Where
- 12 sites in Germany, Hungary and 3 more
- Volunteers
- 72 people
- Sponsor
- AstraZeneca
Healthy Participants, Healthy Glucose
Royal Ancient Oats™ Study
Evaluating the effects of high avenanthramide ancient oat (Royal Ancient Oats™) muffins versus conventional oat muffins in regard to glycemic control.
- Trial name
- RAO (NCT07371598)
- Testing
- Royal Ancient Oat Flour™
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Standard Process Inc.
Pompe Disease, Pompe Disease (Late-onset)
MSOT in Pompe Disease
In patients with Pompe disease (PD) a progressive abnormal lysosomal glycogen storage in muscle tissue leads to impaired muscle function and to degeneration of muscle fibers.
- Conditions
- Pompe Disease, Pompe Disease (Late-onset), Pompe's Disease Juvenile Onset, Pompe Disease Infantile-Onset
- Trial name
- SPOT_PD (NCT05083806)
- Testing
- Multispectral Optoacoustic Tomography
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School