Clinical trials: OAT
Cardiovascular Diseases, Heart Diseases
Electrophysiological Effects of Late PCI After MI
The purpose of this study is to determine if opening blocked arteries with heart balloons and stents prevents heart rhythm problems in individuals 3 to 28 days after a heart attack.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Coronary Disease
- Trial name
- NCT00119847
- Testing
- PCI, Optimal Medical Therapy
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Maryland, Baltimore
Small Cell Lung Carcinoma Extensive Disease
Durvalumab ± Tremelimumab in Combination With Platinum Based Chemotherapy in Untreated Extensive-Stage Small Cell Lung Cancer (CASPIAN)
This is a phase III, randomized, open-label, multicenter, global study to determine the efficacy and safety of combining durvalumab ± tremelimumab with platinum based chemotherapy (EP) followed by durvalumab ± tremelimumab…
- Trial name
- CASPIAN (NCT03043872)
- Testing
- Durvalumab, Tremelimumab, Carboplatin
- Where
- 207 sites in United States, Argentina and 21 more
- Volunteers
- 987 people
- Sponsor
- AstraZeneca
Cardiovascular Diseases, Heart Diseases
Occluded Artery Trial (OAT)
The purpose of this study is to determine whether opening an occluded infarcted artery 3-28 days after an acute myocardial infarction in high-risk asymptomatic patients reduces the composite endpoint of mortality, recurrent…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Heart Failure, Congestive
- Trial name
- OAT (NCT00004562)
- Testing
- Beta adrenergic blockers, Platelet inhibitors, PTCA and stents
- Where
- United States
- Volunteers
- 2,201 people
- Sponsor
- NYU Langone Health
Solid Tumor
A Feasibility Study for the Use of Multispectral Optoacoustic Tomography in the Detection of Tumors
The purpose of this study is to evaluate the safety and potential of a new experimental imaging instrument called multispectral optoacoustic tomography (MSOT) to detect tumors and lymph nodes with tumors.
- Trial name
- OU-SCC-MSOT (NCT04365413)
- Testing
- MSOT Device, Temperature Measurement
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Oklahoma
Colon Adenocarcinoma, Colorectal Carcinoma
Optimization of Adaptive Text Messages for Cancer Survivors (OATS II)
This clinical trial evaluates whether an adaptive text-message intervention is useful in helping survivors of colorectal cancers (CRC) eat more whole grain foods and less refined grain foods.
- Conditions
- Colon Adenocarcinoma, Colorectal Carcinoma, Rectal Adenocarcinoma
- Trial name
- NCT05746195
- Testing
- Dietary intervention via Text Messaging, Survey Administration, Nutrition Education
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- University of California, San Francisco
Knee Injury
Evaluation of the CR Plug for Repair of Defects Created at the Harvest Site From an Autograft in the Knee.
The main objective of this study is to test the ability of an allograft plug to provide a successful repair of an osteochondral defect left at the harvest site during OATS procedure.
- Trial name
- CRB (NCT00821873)
- Testing
- CR Plug
- Where
- 4 sites in United States
- Volunteers
- 9 people
- Sponsor
- RTI Surgical
Iron Absorption
Iron Bioavailability of Fortified Oat Drink
This study will follow a double blinded randomized controlled study design to enroll 20 apparently healthy 6 year old children. The children will be fed with two different nutrient fortified oat drinks labeled with stable…
- Trial name
- NCT01423162
- Testing
- Dietary Intervention (with Vit C then without Vit C), Dietary Intervention (without Vit C followed by with Vit C)
- Where
- Philippines
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Feasibility Study for Thyroid Indication
"Clinical Evaluation of Opto-Acoustic Tomography for Detection and Diagnostic Differentiation of Thyroid Nodules"
Thyroid Feasibility Study
- Trial name
- NCT03032198
- Testing
- Imagio OA/US
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Seno Medical Instruments Inc.
Ulcerative Colitis
Vaccines and Dietary Oats in the Treatment of Ulcerative Colitis
Ulcerative colitis is a chronic inflammatory bowel disease caused by an imbalance between natural defence mechanisms in the intestinal mucosa and microbes in the intestinal lumen.
- Trial name
- NCT00751933
- Testing
- Vaccine Vivotif + Vaccine Dukoral + oats, Vaccine Vivotif + Vaccine Dukoral, Oats
- Where
- Norway
- Volunteers
- 3 people
- Sponsor
- Haukeland University Hospital
Healthy
Phenolic-rich Oats and Artery Improvement
In this proposed human trial, the investigators aim to establish whether consumption of one portion of phenolic acid-rich oats leads to acute improvements (i.e.
- Trial name
- PROGRAIN2 (NCT02731755)
- Testing
- Oat, Control
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Reading
Paroxysmal Atrial Fibrillation
Oral Anticoagulation Therapy Pilot Study
The objective of this study is to determine the safety of discontinuing oral anticoagulation therapy in high risk patients who have had a successful cardiac ablation and remain AF recurrence free for 3 months post ablation.
- Trial name
- OAT (NCT01959425)
- Testing
- Off OAT Group (Test), On OAT Group (Control)
- Volunteers
- 80 people
- Sponsor
- Biosense Webster, Inc.
Platinum Refractory Extensive-Stage Small Cell Lung Carcinoma
A Phase II, Study to Determine the Preliminary Efficacy of Novel Combinations of Treatment in Patients With Platinum Refractory Extensive-Stage Small-Cell Lung Cancer
Study design This is a Phase II, open-label, multi-drug, multi-center, multi-arm, signal-searching study in patients with extensive-stage small-cell lung cancer (SCLC) who have refractory or resistant disease from prior…
- Trial name
- NCT02937818
- Testing
- Durvalumab and Tremelimumab, AZD1775 and carboplatin (CBPT), AZD6738 and olaparib
- Where
- 12 sites in Germany, Hungary and 3 more
- Volunteers
- 72 people
- Sponsor
- AstraZeneca
Small-Cell Lung Cancer
Study of AZD2811 + Durvalumab in ES-SCLC
A Phase II Multicenter, Open-Label, Single Arm Study to Determine the Efficacy, Safety and Tolerability of AZD2811 and Durvalumab Combination as Maintenance Therapy After Induction with Platinum-Based Chemotherapy Combined with…
- Trial name
- TAZMAN (NCT04745689)
- Testing
- Durvalumab, AZD2811, Carboplatin
- Where
- 12 sites in United States, Poland and 2 more
- Volunteers
- 31 people
- Sponsor
- AstraZeneca