Clinical trials: OCD
Obsessive Compulsive Disorder
Quetiapine Augmentation in Severe Obsessive Compulsive Disorder
The purpose of the study is to evaluate the efficacy of quetiapine or placebo added to baseline treatment of SSRI/clomipramine for the treatment of OCD in adult subjects.
- Trial name
- NCT00254735
- Testing
- quetiapine fumarate, SSRI/Clomipramine
- Where
- 2 sites in Germany
- Volunteers
- 44 people
- Sponsor
- AstraZeneca
Obsessive-Compulsive Disorder
Troriluzole (BHV-4157) in Adult Participants With Obsessive Compulsive Disorder
The purpose of this study is to evaluate the efficacy of troriluzole as adjunctive therapy versus placebo in participants with obsessive compulsive disorder (OCD) who had an inadequate response to selective serotonin reuptake…
- Trial name
- NCT03299166
- Testing
- Troriluzole
- Where
- 57 sites in United States
- Volunteers
- 426 people
- Sponsor
- Biohaven Pharmaceuticals, Inc.
Obsessive Compulsive Disorder
Study of NPL-2003 in Adolescents With Obsessive Compulsive Disorder (OCD)
The purpose of this study is to investigate the effect of NPL-2003 on the symptoms of Obsessive Compulsive Disorder (OCD) in an adolescent population.
- Trial name
- NCT00515255
- Testing
- Minocycline
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Neuropharm
Obsessive-compulsive Disorder
Efficacy and Safety Study of Low-Dose Ondansetron For Adjunctive Therapy In Adult Patients With Obsessive-Compulsive Disorder
This study is to assess the efficacy and safety of two doses of ondansetron (0.5 mg and 0.75 mg) relative to placebo when administered twice daily as adjunctive therapy for adult patients with Obsessive-Compulsive Disorder (OCD)…
- Trial name
- NCT01275248
- Testing
- Ondansetron
- Where
- 32 sites in United States, Mexico
- Volunteers
- 130 people
- Sponsor
- Transcept Pharmaceuticals
COPD
A Prospective Observational Study of the Breath Responsive Variable Bolus Oxygen Conserving Device
Evaluate subjects in an prospective observational study Subjects will be administered scientifically validated questionnaires Evaluate Quality Improvement and Oxygen Utilization Improvements. 1.
- Trial name
- BRVB-OCD (NCT02627599)
- Testing
- Breath Responsive Variable Bolus Oxygen Conserving Device
- Where
- 3 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- StratiHealth
Chondral Defect, Osteochondritis Dissecans (OCD)
A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee
The objective of this study is to compare the efficacy and safety of MACI® vs arthroscopic microfracture in the treatment of participants aged 10 to 17 years with symptomatic articular chondral or osteochondral defects of the…
- Conditions
- Chondral Defect, Osteochondritis Dissecans (OCD), Articular Cartilage Defect, Articular Cartilage Disorder of Knee
- Trial name
- PEAK (NCT03588975)
- Testing
- MACI, microfracture
- Where
- 14 sites in United States
- Volunteers
- 45 people
- Sponsor
- Vericel Corporation
Trichotillomania
Feasibility Study for Treating Trichotillomania With Wearable Device and App System
Trichotillomania is characterized by recurrent hair pulling resulting in hair loss causing significant distress and impairment which persists despite repeated attempts to stop.
- Trial name
- NCT04241120
- Testing
- Device and app system designed for participant to self-administer Habit Reversal Training, Reminder bracelet control condition
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- HabitAware Inc.
Osteochondral Lesions of the Knee Joint, Osteochondritis Dissecans (OCD)
MaioRegen Prime Study for the Treatment of Deep Osteochondral Lesion of the Knee
The present study aims to compare the efficacy and the safety of MaioRegen Prime to Debridement (SSOC) in patients with deep osteochondral lesions of the knee joint.
- Conditions
- Osteochondral Lesions of the Knee Joint, Osteochondritis Dissecans (OCD), Early Osteoarthritis
- Trial name
- OSTEOCONFIRM (NCT07332182)
- Testing
- osteochondral scaffold implant, SSOC
- Where
- 10 sites in United States, Italy
- Volunteers
- 400 people
- Sponsor
- Fin-Ceramica Faenza Spa
Medication-refractory Obsessive Compulsive Disorder (OCD)
ExAblate Treatment of Medication Refractory Obsessive Compulsive Disorder
The goal of this prospective, non-randomized, single-arm, single site, feasibility study is to develop and collect data to evaluate the safety and initial effectiveness of this treatment using this ExAblate transcranial System in…
- Trial name
- NCT01986296
- Testing
- ExAblate Transcranial MRgFUS System
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- InSightec
Articular Cartilage Disorder, Degeneration; Articular Cartilage
Chondrofix Osteochondral Allograft Prospective Study
The overall study objective is to evaluate Chondrofix Osteochondral Allograft ("Chondrofix") for the repair of osteochondral lesions in the knee.
- Conditions
- Articular Cartilage Disorder, Degeneration; Articular Cartilage, Chronic Cartilage Injury, Acute Cartilage Injury
- Trial name
- NCT01410136
- Testing
- Chondrofix Osteochondral Allograft
- Where
- 5 sites in United States
- Volunteers
- 29 people
- Sponsor
- Zimmer Orthobiologics, Inc.
Obsessive Compulsive Disorder
Deep Brain Stimulation for Obsessive Compulsive Disorder (OCD PMCF)
The purpose of the study is to monitor the safety and performance of Reclaim® Deep Brain Stimulation (DBS) Therapy in patients with chronic, severe, treatment-resistant Obsessive Compulsive Disorder.
- Trial name
- NCT01135745
- Testing
- Reclaim® Deep Brain Stimulation
- Where
- 8 sites in Belgium, Germany and 5 more
- Volunteers
- 32 people
- Sponsor
- MedtronicNeuro
Trichotillomania
Technology Assisted Treatment for Trichotillomania
The investigators are testing two digital health interventions for trichotillomania (TTM), via a randomized trial design.
- Trial name
- NCT05118633
- Testing
- Keen2 bracelet, Reminder bracelet, Keen2 app
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- HabitAware Inc.
Cartilage or Osteochondral Defects in the Knee
Agili-C™ Implant Performance Evaluation in the Repair of Cartilage and Osteochondral Defects
Evaluate the performance of the Agili-C™ in the repair of Cartilage and Osteochondral defects.
- Trial name
- NCT02423629
- Testing
- Agili-C™ implantation procedure
- Where
- 8 sites in Austria, Belgium and 6 more
- Volunteers
- 143 people
- Sponsor
- Smith & Nephew, Inc.
Obsessive-compulsive Disorders and Symptoms, Obsessive-Compulsive Disorder
An ERP-based Mobile Intervention as an Adjunctive Treatment for OCD
The objective of this feasibility study is to evaluate the feasibility, acceptability, and potential usefulness of the investigational device, a mobile software application (app) (OC Free) for treatment of OCD (contamination…
- Trial name
- NCT05166707
- Testing
- BIXINK OC Free
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- BIXINK Therapeutics Co., Ltd.
Obsessive-Compulsive Disorder
The Safety and Efficacy of Long-term Treatment of PINS Stimulator System for Patients With Obsessive-Compulsive Disorder
The purpose of this clinical study is To verify the long term effectiveness and safety of a bilateral deep brain stimulation (DBS) produced by Beijing PINS Medical Co., Ltd.
- Trial name
- NCT02253472
- Testing
- Deep Brain Stimulation
- Volunteers
- 30 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Osteochondritis Dissecans
Use of Demineralised Bone Matrix (DBX) in Osteochondritis Dissecans (OCD)
This is a 1:1 randomised pilot study in 30 patients in 1 site in Helsinki, Finland. The investigators hypothesize that function, pain, type and quality of cartilage in adult patients with osteochondritis dissecans of the knee…
- Trial name
- NCT01283737
- Testing
- DBX Putty, Mosaicplasty
- Where
- Finland
- Sponsor
- Synthes GmbH
Autism Spectrum Disorder, Depression - Major Depressive Disorder
Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models
This study investigates whether AI-driven analysis of speech can accurately predict clinical diagnoses and assess risk for various mental or behavioral health conditions, including attention-deficit/hyperactivity disorder (ADHD)…
- Conditions
- Autism Spectrum Disorder, Depression - Major Depressive Disorder, Anxiety, Generalized, Bipolar Disorder (BD)
- Trial name
- MINDAIM (NCT06792175)
- Testing
- Solicue Machine Learning Models, Mercuria Machine Learning Models
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Psyrin Inc.
Major Depressive Disorder, Bi-Polar Disorder
DELPhI Evaluation of Psychiatric Conditions
DELPhI acquisition and analysis software, a QuantalX Neuroscience development, which is designed to measure, analyze, and display brain electrical activity of human electroencephalogram (EEG), to transcranial magnetic stimulation…
- Conditions
- Major Depressive Disorder, Bi-Polar Disorder, ADHD, Schizophrenia
- Trial name
- NCT03842345
- Sponsor
- QuantalX Neuroscience
Depression, Anxiety
Focused Ultrasound for Behavioral Health
This is a double-blind, within-participant crossover, multi-site dose-finding study evaluating the safety, feasibility, and preliminary efficacy of repeated low-intensity focused ultrasound (LIFU) stimulation using the ATTN201…
- Conditions
- Depression, Anxiety, Obsessive Compulsive Disorder (OCD)
- Trial name
- VANTUS (NCT07851038)
- Testing
- ATTN201 head-worn focused ultrasound
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Attune Neurosciences Inc
Obsessive-Compulsive Disorder
Child and Adolescent OCD Outcomes From Exposure and Response Prevention Video Teletherapy Treatment
This is a naturalistic, observational study of children and adolescents with obsessive-compulsive disorder who were treated with exposure and response prevention via video teletherapy.
- Trial name
- NCT06466447
- Testing
- Exposure and response prevention therapy
- Where
- United States
- Volunteers
- 2,173 people
- Sponsor
- NOCD