Clinical trials: OCTA
SLE (Systemic Lupus)
Posterior Segment Evaluation of Patients With SLE Using OCT and OCTA
Aim of The Study To evaluate different structural retinal changes using OCT and OCT-A in patients with SLE ; newly diagnosed patients and patients on treatment and compare parameters with normal subjects
- Trial name
- NCT04866615
- Testing
- Optvue OCT
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Minia University
Diabetic Retinopathy, Myopia
OCTA Metrics Repeatability and Reproducibility in Different Disorders
Retinal imaging is a corner stone in diagnosis of most retinal disorders. Standard imaging techniques e.g. fluorescein angiography and color fundus photography have a lot of limitations including limited resolution, invasive…
- Conditions
- Diabetic Retinopathy, Myopia, Choroidal Neovascularization, Healthy
- Trial name
- NCT04488887
- Testing
- Optical coherence tomography angiography
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tanta University
Glaucoma, OCTA
Choroidal and Retinal Features in PACD and POAG on OCT and OCTA
Glaucoma is a group of irreversible, progressive optic neuropathies that can lead to severe visual field defects and even blindness, affecting nearly 95 million people worldwide.
- Conditions
- Glaucoma, OCTA, Choroid
- Trial name
- NCT07580014
- Where
- China
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, Perfusion; Complications
OCTA Analysis of Macular and Papillary Perfusion After Refractive Surgery in Myopes
Refractive surgery for correction of myopia is very common nowadays. However, various refractive techniques may be associated with increase in the IOP, especially during flap creation.
- Trial name
- NCT04424069
- Testing
- Refractive surgery
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Retinal Vascular
Retinal Microvasculature Before and After Silicone Oil by OCTA
Prospective study to assess the retinal microvasculature, optic nerve head vasculature and retinal sensitivity using OCTA and microperimetry before and after silicone oil removal.
- Trial name
- NCT04928196
- Testing
- Microperimtery and optical coherence tomography angiography OCTA
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Glaucoma Open-Angle Primary
OCTA Study of Choroidal Vasculature in Open Angle Glaucoma Patients
The aim of the present study was to examine and measure SFCT and CCVD using respectively EDI-OCT and OCTA in preperimetric and advanced glaucomatous eyes, in order to shed light on the vascular pathogenesis of glaucoma disease.
- Trial name
- NCT05455567
- Testing
- OCTA
- Where
- Italy
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Federico II University
Diabetic Retinopathy
WF and PR OCTA in Diabetic Retinopathy
Diabetic retinopathy (DR) is a leading cause of vision loss in working-age Americans. Capillary damage from hyperglycemia causes vision loss through downstream effects, such as retinal ischemia, edema, and neovascularization…
- Trial name
- NCT03922932
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Exudative Age Related Macular Degeneration
Optical Coherence Tomography Angiography (OCTA) - Directed PDT Triple Therapy
Optical Coherent Tomography Angiography (OCTA)-Directed PDT Triple Therapy for Treatment-Naïve Patients with Exudative Age-related Macular Degeneration (ARMD) versus Standard of Care Anti-VEGF Monotherapy
- Trial name
- NCT04075136
- Testing
- Ranibizumab, Photodynamic laser treatment (PDT), Triamcinolone Acetonide
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Conjunctivitis, Glaucoma
Feasibility Study and Preliminary Application Study on Iris OCTA
All participants will underwent imaging using the OCTA system (Zeiss) with the anterior segment optical adaptor lens. The main outcomes are iris blood flow density and vascular density.
- Conditions
- Conjunctivitis, Glaucoma, Myopia, Diabetic Retinopathy
- Trial name
- NCT03631108
- Testing
- OCTA (ZEISS)
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Non-arteritic Ischemic Optic Neuropathy
Peripapillary and Macular Vascular Changes of Unilateral Anterior Ischemic Optic Neuropathy: An Optical Coherence Tomography Angiography Study
This series aims at studying the peripapillary and macular vascular changes in subjects with unilateral anterior ischemic optic neuropathy via Optical Coherence Tomography Angiography (OCTA).
- Trial name
- NCT06031350
- Testing
- Optical Coherence Tomography Angiography
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Omar Said
PRP
Macular Vessels Density Before and After PRP in Patients With Proliferative Diabetic Retinopathy
In this study, OCTA is used to study the vascular changes following PRP in patients with PDR; regarding vessels density at 1 month and 6 months follow up period and measure superficial, deep, and outer retina for fovea…
- Trial name
- NCT04976361
- Testing
- PRP was done using visulas green laser machine (Carl Zeiss Meditec AG Geoschwitzer Str. 51-52,07745 jena, Germany)
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Minia University
Congenital Heart Disease, Children, Only
Optical Coherence Tomography Angiography (OCTA) in Children's Cardiac Surgery
Around 3500 children including 1,000 babies a year in the UK require heart surgery. Open-heart repairs involve the heart being stopped, while blood is pumped around the body using a cardiopulmonary bypass machine.
- Trial name
- OCTA (NCT05568849)
- Testing
- OCTA measurements
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Normal Eyes and Ocular Pathology
Precision of OCT and OCTA-based Ocular Measurements
Precision of OCT- and OCTA-based Ocular Measurements
- Trial name
- NCT03859310
- Testing
- SD-OCT
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Optovue
Age Related Macular Degeneration
OCTA and Retinal Angiomatous Proliferation
To investigate, using optical coherence tomography angiography, the retinal vascular features in patients affected by RAP.
- Trial name
- NCT04689789
- Testing
- optical coherence tomography angiography
- Where
- Italy
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Federico II University
Macular Holes
Macular Micro Vascular Changes Following Macular Hole Repair : Optical Coherence Tomography Angiography Study
The goal of this prospective interventional study is to to compare the micro vascular and structural changes between surgery with and without ILM flap to repair macular hole.
- Trial name
- NCT06233500
- Testing
- pars plana vitrectomy
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Fayoum University
Diabetic Retinopathy
Assessment of Retinal Microvascular Changes by OCT Angiography in Diabetic Retinopathy
This observational cross-sectional study aims to assess retinal microvascular changes using optical coherence tomography angiography (OCTA) in patients with diabetic retinopathy.
- Trial name
- NCT07747428
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Open Angle Glaucoma
OCTA in Patients With Primary Open-angle Glaucoma
Is to investigate retinal microvascular changes in primary open angle glaucoma patients using Optical Coherence Tomography Angiography.
- Trial name
- NCT06214676
- Testing
- OCT angiography
- Volunteers
- 30 people
- Sponsor
- Assiut University
GPA, Vasculitis
Ocular Manifestations of Granulomatosis With Polyangiitis.
The current state of knowledge on ANCA-associated vasculitis (AAV) indicates that it is a group of autoimmune diseases in which small blood vessels in various organs are affected.
- Conditions
- GPA, Vasculitis, Microscopic Polyangiitis (MPA), Churg-Strauss Syndrome (CSS)
- Trial name
- NCT07664709
- Testing
- Optical coherence tomography angiography
- Where
- Poland
- Volunteers
- 70 people
- Sponsor
- Military Institute od Medicine National Research Institute
Choroidal Neovascularization
OCTA Insights in CNVM, Morphological Characteristics and Correlation With Structural OCT.
To suggest a novel classification of choroidal neovascular membrane based on optical coherence tomography angiography and to correlate morphological characteristics based on optical coherence tomography with clinical criteria of…
- Trial name
- NCT05055973
- Volunteers
- 80 people
- Sponsor
- Assiut University
Angiography, Glaucoma, Open-Angle
The Relationship Between Macular OCTA and GCIPL and Their Combinational Index Using AI
Macular GCIPLT and vessel density will be measured with Spectralis optical coherence tomography and Topcon swept-source OCT respectively.
- Trial name
- NCT03369886
- Testing
- Optical Coherence Tomography Angiography (OCTA)
- Where
- South Korea
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital