Clinical trials: OSA, open to volunteers
Obstructive Sleep Apnea (OSA), Snoring
Effects of Frequency Adjustment in Functional Electrical Stimulation on Genioglossus Muscle Activity
This single-group interventional study investigates the safety and physiologic effects of functional electrical stimulation (FES) applied to the tongue and submental muscles in adults at high risk for sleep apnea.
- Trial name
- NCT07466888
- Testing
- Functional Electrical Stimulation Device
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Sleep Apnea Syndromes
Efficacy Investigation of the Medical Device Apneal® on Smartphone for Sleep Apnea-Hypopnea Syndrome Diagnosis
The goal of this clinical trial is to evaluate the effectiveness of the Apneal® app in diagnosing sleep apnea syndrome (SAS) in adults who require polysomnography (PSG) as part of routine care.
- Trial name
- SESAME (NCT06578390)
- Testing
- Apneal device
- Where
- 11 sites in France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Mitral
Snoring, Obstructive Sleep Apnea (OSA)
Validation of a Snoring App Against Commercially Available Applications and PSG
This study will compare the output of a new snoring application against another commercially available application and polysomnography (either home or in-laboratory).
- Trial name
- NCT07097597
- Testing
- Comparison 1: New Snoring Application, Comparison 2: Commercially Available Snoring Application, Comparison 3: Polysomnography
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Windsor Sleep Disorders Clinic
Schizoaffective Disorder, Schizophrenia
Obstructive Sleep Apnea Treatment in Serious Mental Illness
Serious mental illnesses (SMI) like schizophrenia and bipolar disorder are two of the most disabling and costly chronic illnesses worldwide.
- Conditions
- Schizoaffective Disorder, Schizophrenia, Bipolar Disorder, Obstructive Sleep Apnea of Adult
- Trial name
- NCT05457127
- Testing
- Automatic Positive Airway Pressure (APAP)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obstructive Sleep Apnea
Safety and Effectiveness of Slow Wave Device for the Treatment of Obstructive Sleep Apnea
This is a safety and efficacy trial for a Slow Wave, Inc. UASD oral appliance for the treatment of Obstructive Sleep Apnea. This trial will recruit 60-80 participants through our IRB partner.
- Trial name
- NCT06519149
- Testing
- Slow Wave UASD
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Slow Wave, Inc.
Obstructive Sleep Apnea, Obstructive Sleep Apnea (OSA)
Identification of Biomarkers of Obstructive Sleep Apnea.
Obstructive sleep apnea (OSA) is a common sleep disorder associated with intermittent hypoxia, systemic inflammation, oxidative stress, and an increased risk of cardiovascular and metabolic diseases.
- Conditions
- Obstructive Sleep Apnea, Obstructive Sleep Apnea (OSA), Obstructive Sleep Apnea (OSAS), Obstructive Sleep Apnea (SAOS)
- Trial name
- NCT07723144
- Testing
- Positive Airway Pressure (PAP) Therapy
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Obstructive Sleep Apnea (OSA), Snoring
OSAHS Screening in Diverse Populations
The goal of this prospective observational study is to learn about the current prevalence of obstructive sleep apnea-hypopnea syndrome in community population, patients with specific diseases and special population from China.
- Conditions
- Obstructive Sleep Apnea (OSA), Snoring, Prevalence, Questionnaires and Surveys
- Trial name
- NCT07736872
- Testing
- patients with hypertension, diabetes, cardiovascular and cerebrovascular diseases, chronic obstructive pulmonary disease, asthma and other OSA related comorbidities.
- Where
- 2 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Kang Wu
Obstructive Sleep Apnea (OSA)
Evaluation of the Diagnostic Capacity of a Smart Mattress Versus Conventional Polysomnography
This project aims to develop and evaluate an innovative, non-invasive diagnostic system based on a smart mattress for detecting obstructive sleep apnea (OSA), as well as assessing overall sleep quality and identifying periodic…
- Trial name
- NCT07432919
- Testing
- Integrated polysomnographic assessment with smart mattress.
- Where
- 2 sites in Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospital San Pedro de Logroño
Obstructive Sleep Apnea of Adult
An Extension Study to Assess the Long-term Safety of the Genio® System
The objective of this study is to assess the long-term safety of the Genio® system in adult OSA patients with and without complete concentric collapse of the soft palate who have successfully been implanted with the Genio IS in a…
- Trial name
- OLE (NCT05939141)
- Testing
- Genio System
- Where
- 7 sites in Australia
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Nyxoah S.A.
Obstructive Sleep Apnea
Exploring the Use of Phototherapy to Improve CPAP Compliance
Photobiomodulation (PBM) is a type of light therapy like lasers and LEDs. PBM was previously known by different terms like "low-level laser therapy" (LLLT) or "photobiostimulation." LLLT, despite its name, can also have effects…
- Trial name
- NCT06960161
- Testing
- Phototherapy
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Continuous Positive Airway Pressure, Adverse Effect
Addressing Unintentional Leakage When Using Nasal CPAP - Study A
Oral unintentional leak is a common side effect of continuous positive airway pressure (CPAP) for obstructive sleep apnea (OSA) treatment.
- Conditions
- Continuous Positive Airway Pressure, Adverse Effect, Obstructive Sleep Apnea
- Trial name
- NCT06570616
- Testing
- CPAP (fixed mode), APAP (automatic mode)
- Where
- 2 sites in Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Obesity & Overweight, Pediatric Obesity
Ultrasound Assessment of Tongue Characteristics in Children and Adolescents With Obesity
This longitudinal observational study aims to validate ultrasound-based tongue markers related to tongue characteristics, including fat accumulation, morphologic and mechanical properties of the tongue in children and adolescents…
- Conditions
- Obesity & Overweight, Pediatric Obesity, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT07370350
- Testing
- Submental ultrasound
- Where
- 2 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haute Ecole Bruxelles-Brabant
Obstructive Sleep Apnea of Child
Diaphragm Ultrasound İn Children With OSAS
This is a prospective observational study evaluating perioperative diaphragmatic function by ultrasonography in children aged 1-12 years undergoing elective surgery under general anesthesia.
- Trial name
- NCT07380321
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Bronchial Asthma, Bronchiectasis
The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease
Research is being conducted into chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease, and bronchiectasis.
- Conditions
- Bronchial Asthma, Bronchiectasis, ILD, COPD
- Trial name
- NCT07060079
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University College, London
Obstructive Sleep Apnea
PAP Systems External Clinical Studies (ECS)
This is a pre-market study for ongoing product development aiming to explore the usability and performance of the study PAP systems.
- Trial name
- NCT06562205
- Testing
- PAP System A (with Amalfi) then PAP System B (with CLA11), PAP System B (with CLA11) then PAP System A (with Amalfi)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ResMed
Opiod Use Disorder, Obstructive Sleep Apnea
Effects of Mental Tasks on Breathing Patterns in Adults Using Chronic Opioids vs Non-opioid Users.
The goal of this observational study is to find out if using your brain for a mental task changes how you breathe. Researchers want to compare three groups of adults: people who take opioid pain medicine every day, people with…
- Trial name
- AWAKE (NCT07829055)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obstructive Sleep Apnea (OSA)
Heart and Brain Blood Flow in Obstructive Sleep Apnea
Obstructive sleep apnea causes repeated pauses in breathing during sleep. Breathing efforts against an occluded airway may change how blood flows through the heart and how blood drains from the brain.
- Trial name
- OSA4DFlow (NCT07913269)
- Where
- 2 sites in Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obstructive Sleep Apnea (OSA)
Intermittent-Hypoxia Inhibits Neutrophil Extracellular Traps Formation: Role of Cathelicidins
The study will enroll 80 moderate-to-severe Obstructive sleep apnea (OSA) patients (40 obese) and 40 age-, gender-, and body mass index-matched controls.
- Trial name
- NCT07129486
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kun-Ta Chou
Sleep Apnea, Obstructive
Use of Passive Myofunctional Appliances for Snoring and Mild Obstructive Sleep Apnea
It is unknown whether passive myofunctional appliances can be used for the treatment of obstructive sleep apnea and snoring, nor how to select the appropriate size per individual patient.
- Trial name
- NCT05497180
- Testing
- passive myofunctional appliance, standard oral appliance
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Obstructive Sleep Apnea
Functional Capacity in Obstructive Sleep Apnea
Obstructive sleep apnea syndrome (OSAS) is a condition characterized by a deterioration in respiratory function and an increase in the activity of accessory respiratory muscles.
- Trial name
- NCT07913139
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Karabuk University