Clinical trials: OSAS
Obstructive Sleep Apnea, Hypopnea
Armodafinil (CEP-10953) in Treatment of Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome(OSAHS)
The primary objective of this study is to determine whether treatment with Armodafinil (CEP-10953) is more effective than placebo treatment for patients with excessive sleepiness associated with obstructive sleep apnea/hypopnea…
- Trial name
- NCT00078325
- Testing
- Armodafinil 250 mg/day, Armodafinil 150 mg/day
- Volunteers
- 395 people
- Sponsor
- Cephalon
Sleep Apnea, Obstructive
cNEP for the Treatment of Obstructive Sleep Apnea
The purpose of this study is to determine whether cNEP (continuous positive external pressure) is effective in treating obstructive sleep apnea
- Trial name
- cNEP (NCT02677168)
- Testing
- cNEP
- Where
- Canada
- Volunteers
- 71 people
- Sponsor
- Sommetrics, Inc.
Obstructive Sleep Apnea
Evaluation of a Novel Auto-Adjusting Positive Airway Pressure Algorithm for the Treatment of Obstructive Sleep Apnea Clinical Study
This study aims to assess the effectiveness of an investigational algorithm in the treatment of obstructive sleep apnea.
- Trial name
- NCT06769607
- Testing
- Investigational algorithm, Control algorithm
- Where
- Australia
- Volunteers
- 80 people
- Sponsor
- ResMed
Obstructive Sleep Apnea
RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA
The goal of this randomised, double-blind phase II/III clinical trial is to determine the safety and efficacy of IHL-42X in subjects with obstructive sleep apnoea who are intolerant, non-compliant, or naïve to positive airway…
- Trial name
- REPOSA (NCT06146101)
- Testing
- IHL-42X Low Dose, IHL-42X High Dose, IHL-42X (Optimal Dose)
- Where
- 20 sites in United States
- Volunteers
- 121 people
- Sponsor
- Incannex Healthcare Ltd
Obstructive Sleep Apnea
Pilot Study of Negative Pressure Sleep Therapy System to Treat Obstructive Sleep Apnea
This is a pilot study to investigate the efficacy and safety of the Negative Pressure Sleep Therapy System for the treatment of obstructive sleep apnea.
- Trial name
- NCT02324790
- Testing
- iNAP® Sleep Therapy System
- Where
- 4 sites in Taiwan
- Volunteers
- 34 people
- Sponsor
- Somnics, Inc.
Obstructive Sleep Apnea
CPAP In-home Assessment USA
The study is to evaluate the product reliability, therapy effectiveness and user feedback of a Continuous Positive Airway Pressure (CPAP) device in-home for up to 6 months.
- Trial name
- NCT02809859
- Testing
- Fisher & Paykel Healthcare CPAP Device
- Where
- 4 sites in United States
- Volunteers
- 139 people
- Sponsor
- Fisher and Paykel Healthcare
Narcolepsy, Obstructive Sleep Apnea
Evaluate Sunosi® PK in Breast Milk and Plasma of Healthy Postpartum Women Following Single Dose Oral Administration
The purpose of study JZP110-401 is to evaluate solriamfetol pharmacokinetics (PK) in the breast milk and plasma of healthy postpartum women following the administration of the drug.
- Conditions
- Narcolepsy, Obstructive Sleep Apnea, Excessive Daytime Somnolence, Excessive Sleepiness
- Trial name
- NCT05008341
- Testing
- Solriamfetol 150 mg Oral Tablet
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Axsome Therapeutics, Inc.
Obstructive Sleep Apnea
A Development Study to Evaluate a Nasal Mask for the Treatment of Obstructive Sleep Apnea
This investigation is designed to evaluate the comfort, ease of use and performance of a trial nasal mask for the treatment of Obstructive Sleep Apnea (OSA) in the home environment.
- Trial name
- NCT03124069
- Testing
- F&P Saturn
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Clinical Evaluation of a Wearable Technology for the Diagnosis of Sleep Apnoea
This trial will aim to test a new wearable device for the diagnosis of Sleep Apnoea.
- Trial name
- NCT04028011
- Testing
- Novel Wearable device
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Acurable Ltd.
Obstructive Sleep Apnea
CPAP In-home Assessment Australia
The study is to evaluate the product reliability, therapy effectiveness and user feedback of a Continuous Positive Airway Pressure (CPAP) device in-home for up to 6 months.
- Trial name
- NCT02809794
- Testing
- Fisher & Paykel Healthcare CPAP Device
- Where
- 3 sites in Australia
- Volunteers
- 50 people
- Sponsor
- Fisher and Paykel Healthcare
Sleep Apnea, Obstructive
Adherence and Quality of Life of CPAP for Obstructive Sleep Apnea
A multicentre, randomized controlled trial (RCT) design.The control group followed the usual treatment, while the intervention group (PIMA) followed the treatment with an adapted and flexible care plan depending on…
- Trial name
- PIMA1-JO-PR (NCT04691479)
- Testing
- Motivational Interview (MI) & Adherence Follow-Up, Adherence Follow-Up
- Where
- Spain
- Volunteers
- 129 people
- Sponsor
- Air Liquide Healthcare Spain
Obstructive Sleep Apnea
Workflow Validation of an In-Home Feedback Controlled Mandibular Positioner
The purpose of the study is to test the workflow of the MATRx and MATRx plus feedback controlled mandibular positioner in its intended setting and considerations related to decision making by the care provider.
- Trial name
- NCT03616327
- Testing
- MATRx in-lab, MATRx plus
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Zephyr Sleep Technologies
Obstructive Sleep Apnea (OSA) and Obesity
A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of HDM1005 Injection in Subjects With Obstructive Sleep Apnea (OSA) and Obesity Not Receiving Positive Airway Pressure (PAP) Therapy
This is a 56-week randomized, double blinded, parallel-controlled study evaluating the efficacy and safety of the HDM1005 in patients with obstructive sleep apnea (OSA) and obesity not receiving positive airway pressure (PAP)…
- Trial name
- NCT07787260
- Testing
- HDM1005
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Obstructive Sleep Apnea
The Evaluation of the Toffee Mask for the Treatment of Obstructive Sleep Apnea
This investigation is a prospective, non-randomized, non-blinded study. This investigation is designed to evaluate the performance, comfort and ease of use of the F\&P Toffee mask amongst Obstructive Sleep Apnea (OSA) patients.
- Trial name
- NCT03726346
- Testing
- Toffee Full Face Mask
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
AutoSet for Her Clinical Trial Protocol
The purpose of this study is to assess the efficacy and user preference of the Newport AutoSet for Her in female obstructive sleep apnea (OSA) patients.
- Trial name
- NCT01826513
- Testing
- Standard AutoSet algorithm, Modified AutoSet algorithm
- Where
- Australia
- Volunteers
- 25 people
- Sponsor
- ResMed
Obstructive Sleep Apnea (OSA)
Improved Automatic CPAP Algorithm to Treat Obstructive Sleep Apnea (OSA)
The purpose of this study is to compare a modified AutoSet algorithm running on research hardware versus the traditional AutoSet algorithm running on an S7 AutoSet Spirit.
- Trial name
- NCT00850434
- Testing
- Modified AutoSet Algorithm, Standard AutoSet Algorithm
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- ResMed
OSA - Obstructive Sleep Apnea, Obesity
A Study of XW003 in Obese Participants With Obstructive Sleep Apnea Receiving Positive Airway Pressure Therapy
The aim of the study is to assess the efficacy and safety of XW003 injections in obese participants with OSA receiving PAP
- Trial name
- NCT07434050
- Testing
- XW003 injection
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Hangzhou Sciwind Biosciences Co., Ltd.
Obstructive Sleep Apnea, Hypertension
Trial of AD113 and Atomoxetine in OSA Patients With Hypertension
This is a randomized, double blind, 2-period, non placebo-controlled crossover study in patients with moderate to severe OSA and controlled hypertension, comparing atomoxetine with AD113
- Trial name
- NCT04905979
- Testing
- AD113, Atomoxetine
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Apnimed
Sleep Apnea, Obstructive
The Advance Trial. Tongue Advancement for Obstructive Sleep Apnea: An Evaluation of the Aspire Medical Advance System
The objective of the study is to assess the effectiveness of the Aspire Medical Advance System in obstructive sleep apnea by demonstrating a statistically significant mean reduction in the apnea-hypopnea index (AHI) from baseline…
- Trial name
- NCT00467324
- Testing
- Aspire Medical Advance System
- Where
- 4 sites in United States
- Volunteers
- 42 people
- Sponsor
- Aspire Medical
Sleep-Disordered Breathing, Obstructive Sleep Apnea
A Multi-Center Study to Assess the Performance of Saturation Patterns.
A multi-center, prospective, single-visit study designed to acquire physiologic pulse oximeter waveform data during standard polysomnography (PSG) studies performed at multiple different Sleep Lab Centers.
- Conditions
- Sleep-Disordered Breathing, Obstructive Sleep Apnea, Sleep Apnea, Central Sleep Apnea
- Trial name
- NCT00775346
- Where
- 3 sites in United States
- Volunteers
- 92 people
- Sponsor
- Medtronic - MITG