Clinical trials: OSAS
Obstructive Sleep Apnea
Mechanism of Endothelial Dysfunction in Obstructive Sleep Apnea (OSA)
The investigators hypothesized that patients with Obstructive Sleep Apnea (OSA) who are free of any cardiovascular disease will have early microcirculatory changes that are unique to OSA, and therefore would resolve with…
- Trial name
- NCT01027078
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Sleep Apnea, Obstructive
Tongue Advancement for Obstructive Sleep Apnea
The objective of this study is to assess the feasibility, safety and effectiveness of tongue stabilization using Aspire Medical Advance™ System for the treatment of obstructive sleep apnea (OSA).
- Trial name
- NCT00490984
- Testing
- Aspire Medical Advance System
- Where
- 3 sites in Belgium, Czechia and 1 more
- Volunteers
- 60 people
- Sponsor
- Aspire Medical
Obstructive Sleep Apnea (OSA), Rapid Maxillary Expansion
Changes in Polysomnography and Rhinomanometry Parameters After Rapid Maxillary Expansion or Adenotonsilectomy in Children With Obstructive Sleep Apnea
Adenotonsillectomy (AT) is considered the most effective and the standard treatment for Obstructive Sleep Apnea (OSA) in children.
- Conditions
- Obstructive Sleep Apnea (OSA), Rapid Maxillary Expansion, Polysomnography
- Trial name
- NCT07069543
- Testing
- Adenotonsillectomy, Rapid maxillary expansion
- Where
- Brazil
- Volunteers
- 51 people
- Sponsor
- Federal University of Minas Gerais
Sleep Apnea, Obstructive, Pregnancy Related
Efficacy of Oral Appliances on Obstructive Sleep Apnea During Pregnancy
Issue: The prevalence and severity of sleep-disordered breathing increases during pregnancy due to weight gain, physiological and hormonal changes.
- Trial name
- OSApod (NCT03138291)
- Testing
- Somnodent
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Obstructive Sleep-Apnea Syndrome
Evaluation of Prolidase in Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea (OSA) is a highly prevalent breathing disorder in sleep. We have aimed to evaluate the relationship between OSA and prolidase activity, the oxidative stress index (OSI), total antioxidative capacity (TAC)…
- Trial name
- NCT03563118
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Sakarya University
Obstructive Sleep Apnea, Non-alcoholic Fatty Liver
Free Walking Exercise in Obstructive Sleep Apnea Patients With Non-alcoholic Fatty Liver
Research evaluating the impact of continuous positive airway pressure (CPAP) \& walking exercise on fatigue severity, liver enzymes and sleeping quality in patients with non-alcoholic fatty liver disease who also have obstructive…
- Trial name
- NCT06508190
- Testing
- continuous positive airway pressure, free walking exercise and continuous positive airway pressure
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ahram Canadian University
Obstructive Sleep Apnea
Dexamethasone Treatment for OSA in Children
This is a double-blinded clinical trial of children diagnosed with moderate to severe obstructive sleep apnea (OSA) on a baseline polysomnogram (PSG).
- Trial name
- NCT05638087
- Testing
- Dexamethasone
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- The Hospital for Sick Children
Obstructive Sleep Apnea
Brain Fog in Sleep Apnea
Objective: This observational, cross-sectional pilot study aims to assess "Brain Fog" (cognitive symptoms impacting memory, attention, and concentration) in severe Obstructive Sleep Apnea (OSA) patients.
- Trial name
- BF -OSA (NCT06664450)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Asthma, Wheeze
The Development of Novel Clinical Tests to Diagnose and Monitor Asthma in Preschool Children
The study will ascertain the ability of preschool lung function tests to distinguish healthy children from those with wheeze, and to differentiate phenotypes of wheezy children (high and low risk for asthma as defined by API) in…
- Conditions
- Asthma, Wheeze, Obstructive Sleep Apnea, Food Allergy
- Trial name
- WheezyER (NCT02743663)
- Testing
- Bronchodilator response, Allergy Skin Test, Multiple-Breath Washout
- Where
- Canada
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Obstructive Sleep Apnea
A Development Study to Evaluate a Full-Face Mask for the Treatment of Obstructive Sleep Apnea
This investigation is designed to evaluate the comfort, ease of use and performance of a trial nasal mask for the treatment of Obstructive Sleep Apnea (OSA) in the home environment.
- Trial name
- NCT03272763
- Testing
- F&P Toffee mask
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea of Adult
Does Race Make a Difference in Obstructive Sleep Apnea?
Obstructive sleep apnea (OSA) is a sleep-related breathing disorder, often associated with a compromised upper airway space and an increase in upper airway collapsibility.
- Trial name
- NCT03463785
- Testing
- cone beam computed tomography
- Where
- 2 sites in China, Netherlands
- Volunteers
- 58 people
- Sponsor
- Academic Centre for Dentistry in Amsterdam
OSA
Using an Educational Video to Enhance Adherence of CPAP Therapy in Thai OSA Patients: a Randomised Controlled Trial
The goal of this clinical trial is to find out whether video education helps improve CPAP adherence in OSA patients or not The main questions it aims to answer are: Does educational video intervention help improve CPAP adherence…
- Trial name
- NCT06684717
- Testing
- Educational video intervention
- Where
- Thailand
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Obstructive Sleep Apnea, Vascular Aneurysm
OSA as a Remote Ischemic Preconditioning in Vascular Surgery
Ischemia and reperfusion (I/R) injury during abdominal aortic aneurysm (AAA) repair is inevitable and may lead to postoperative multi-organ failure.
- Conditions
- Obstructive Sleep Apnea, Vascular Aneurysm, Ischemia Reperfusion Injury
- Trial name
- NCT04630535
- Testing
- aorto-bifemoral bypass surgery
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Sleep Apnea, Obstructive
Effects of Suboptimal CPAP Therapy on Symptoms of Obstructive Sleep Apnoea
Obstructive sleep apnoea (OSA) is a highly prevalent sleep-related breathing disorder. The most effective treatment for OSA is continuous positive airway pressure (CPAP).
- Trial name
- NCT02781740
- Testing
- Continous Positive Air Pressure Device
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Zurich
OSA, OSAS
Maxillomandibular Advancement in the Treatment of Obstructive Sleep Apnea
ABSTRACT OBJECTIVES: To study the correlation between pharyngeal airway volume (PAV), the clinical indicators of obstructive sleep apnea (AHI, ESS), and the impact of orthognathic surgery on them.
- Conditions
- OSA, OSAS, Apnea, Obstructive Sleep, Orthognathic Surgery
- Trial name
- NCT03796078
- Testing
- Maxillomandibular advancement, monomaxillary surgery (isolated MaxS), monomandibullary surgery (MandS)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centro Medico Teknon
Obstructive Sleep Apnea (OSA), Bariatric Surgery
Desaturations and Nursing Interventions in Patients Receiving Supplemental Oxygen Therapy After Metabolic and Bariatric Surgery
The goal of this observational study is to learn about the effect of supplemental oxygen therapy during the first night after bariatric and metabolic surgery in a population that is not (routinely) tested for obstructive sleep…
- Trial name
- SATBAR (NCT07174674)
- Where
- Netherlands
- Volunteers
- 563 people
- Sponsor
- Rijnstate Hospital
Obstructive Sleep Apnea, Metabolic Syndrome
Effects of CPAP on Cardiovascular Risk in Obstructive Sleep Apnea (OSA) and Metabolic Syndrome
The increased risk of atherosclerotic morbidity and mortality in patients with obstructive sleep apnea (OSA) has been linked to arterial hypertension, insulin resistance, systemic inflammation, and oxidative stress in previous…
- Trial name
- NCT00635674
- Testing
- CPAP device - REMstar Plus, Respironics, Murrysville, USA
- Where
- Slovakia
- Volunteers
- 32 people
- Sponsor
- Pavol Jozef Safarik University
Sleep Apnea Syndromes, Sleep Apnea
Mandibular Advancement Device for Obstructive Sleep Apnea
The purpose of this study was to determine how effective a custom-made standard dental splint (activator) advancing the lower jaw forward is in treatment of obstructive sleep apnea, and further to find factors for identification…
- Conditions
- Sleep Apnea Syndromes, Sleep Apnea, Obstructive Sleep Apnea
- Trial name
- NCT00243139
- Testing
- Mandibular advancement device (activator)
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Nykøbing Falster County Hospital
Obstructive Sleep Apnea (OSA)
Safety and Tolerability of Gefapixant (MK-7264) in Participants With Obstructive Sleep Apnea (MK-7264-039)
The purpose of this study is to assess the safety and tolerability of multiple dose administration of gefapixant (MK-7264) in participants with moderate to severe obstructive sleep apnea (OSA).
- Trial name
- NCT03882801
- Testing
- Gefapixant
- Where
- 5 sites in United States, Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Obstructive Sleep Apnoea, Inflammation
Investigating the Neuropathology of Obstructive Sleep Apnoea
Our multi-disciplinary research group works closely with people who have obstructive sleep apnoea. This is a life-long illness that causes breathing to stop during sleep, which leads to low-oxygen in the blood.
- Trial name
- INcOSA (NCT02967536)
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- King's College London
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.