Clinical trials: OSAS
Obstructive Sleep Apnea
Belun Ring Validation Study for Assessment of Obstructive Sleep Apnea
This study aims to determine the overall accuracy, sensitivity, and specificity of the Belun Ring device in evaluating obstructive sleep apnea by comparing the device to the attended overnight in-lab polysomnography which is the…
- Trial name
- NCT03997916
- Testing
- Belun Ring, PSG
- Where
- 2 sites in United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Heart Failure, Obstructive Sleep Apnea
The Role of Sleep Apnea in the Acute Exacerbation of Heart Failure
This study will evaluate whether treating sleep apnea while in the hospital would help heart failure, and assist recovery from the worsening of the heart function more than the current clinical standard of waiting for treatment…
- Conditions
- Heart Failure, Obstructive Sleep Apnea, Heart Failure, Congestive
- Trial name
- NCT00679549
- Testing
- CPAP Therapy
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Ohio State University
OSA, Malocclusion
Changes of the Upper Airway Volume After Orthognathic Surgery
The aim of the present project is to analyze the impact from orthognathic surgery on the upper airway respiratory volume. The primary objective is comparison of differences in the in the airway changes due to maxillary movements…
- Conditions
- OSA, Malocclusion, Dentofacial Deformities
- Trial name
- NCT05060133
- Testing
- Orthognathic Surgery
- Where
- Sweden
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Lund University Hospital
COVID, Obstructive Sleep Apnea
Obstructive Sleep Apnea & Covid-19 Outcomes
Covid-19 infection is an on-going pandemic with worse diagnosis in adults with comorbid conditions such as hypertension and cardiopulmonary diseases.
- Conditions
- COVID, Obstructive Sleep Apnea, Pneumonia
- Trial name
- OSACOVID-19 (NCT04363333)
- Testing
- Home Sleep Apnea Testing or In-hospital Polysomnography
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 320 people
- Sponsor
- Koç University
Obstructive Sleep Apnea
Vascular Pathophysiology in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a medical problem whose importance is increasing in recognition and awareness. The National Commission on Sleep Disorders estimates that 15 million Americans have OSA, many of whom remain…
- Trial name
- NCT00214084
- Testing
- Allopurinol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Sleep Apnea, Obstructive
Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome
The primary objectives of the study are to determine the effectiveness of PROVIGIL treatment, compared to placebo treatment, in children and adolescents with excessive sleepiness (ES) associated with obstructive sleep…
- Trial name
- NCT00107809
- Testing
- Modafinil
- Where
- 64 sites in United States, Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cephalon
Sleep Apnea
Obstructive Sleep Apneas in Elderly:Neuroimaging Changes and Neurocognitive Function Before and After Treatment
In the near future more than 20% of the European population will be over 65 years old and the prevalence of obstructive sleep apnea (OSA) in this aged population is known to be higher than 50%.
- Trial name
- NCT01826032
- Testing
- CPAP, Standard care for OSA
- Where
- Spain
- Volunteers
- 33 people
- Sponsor
- Hospital Clinic of Barcelona
Obstructive Sleep Apnea (OSA), Sleep
Effectiveness of Inspiratory Muscle Training on Sleep in Patients With Obstructive Sleep Apnea
The goal of this clinical trial is to evaluate the effectiveness of inspiratory Muscle Training (IMT) on both objective and subjective sleep parameters in patients with OSA.Methods: A prospective, randomized, controlled clinical…
- Trial name
- NCT07149233
- Testing
- Inspiratory Muscle Training
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
Adenotonsillectomy, Obstructive Sleep Apnea (OSA)
Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstructive Sleep Apnea
Emphasize that the usage of multimodal analgesia in managing perioperative pain in children with mild to moderate Obstructive Sleep Apnea undergoing adenotonsillectomy may achieve the same efficacy of fentanyl with less…
- Conditions
- Adenotonsillectomy, Obstructive Sleep Apnea (OSA), Fentanyl, Opioid
- Trial name
- NCT07435493
- Testing
- Group A: Fentanyl-Based Analgesia, Group B: Opioid-Free Multimodal Analgesia
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Obstructive Sleep Apnea, Obesity
Obesity and Obstructive Sleep Apnea (OSA) in Children
The goal of this research is to study the prevalence of sleep disordered breathing and associated morbidity in obese children and to examine the role of diet and physical activity in the treatment of sleep-disordered breathing in…
- Trial name
- NCT01135147
- Testing
- Diet, Surgery
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Obstructive Sleep Apnea
TheraPAP Equivalence Crossover Study
The present study, TheraEquivalence, is a Phase 2 crossover study designed to examine the efficacy and safety of TheraPAP (TPAP) vs. CPAP alone in the treatment of OSA.
- Trial name
- NCT06238362
- Testing
- TPAP, CPAP
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- SleepRes Inc.
Obstructive Sleep Apnea, Sleep Apnea
Continuation Protocol for Study Using Negative Pressure to Reduce Apnea Trial
The goal of this study is to allow continued access to the aerSleep II System for subjects that have completed the SOM-029 study until the device is commercially available.
- Trial name
- CO-STAR (NCT05608486)
- Testing
- aerSleep II
- Sponsor
- Sommetrics, Inc.
Recurrent Tonsillitis, Obstructive Sleep Apnea
Post-operative Pain Control After Pediatric Adenotonsillectomy
Adenotonsillectomy is one of the most common surgical procedures performed in the pediatric population in the United States. It is generally a well-tolerated procedure with post-operative bleeding risk ranging from 3-5% in…
- Conditions
- Recurrent Tonsillitis, Obstructive Sleep Apnea, Sleep Disordered Breathing, Adverse Reaction to Drug
- Trial name
- NCT02296840
- Testing
- Ibuprofen, Hydrocodone-Acetaminophen
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Emory University
Obstructive Sleep Apnea
PAP Therapy Sleep Apnea and Exercise
Positive airway pressure (PAP) therapy is generally offered to patients with obstructive sleep apnea. The investigators suggest that beneficial effects of PAP therapy is by preventing apneas and therefore reducing cardiac and…
- Trial name
- NCT01786291
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- University of Gaziantep
Obstructive Sleep Apnea Hypopnea Syndrome
Contribution of Drug Induced Sleep Endoscopy of Pediatric Obstructive Sleep Apnea Hypopnea Syndrome
The role of drug-induced sleep endoscopy (DISE) in the management of obstructive sleep apnea hypopnea syndrome (OSAHS) is not precisely defined for children.
- Trial name
- ESSI (NCT03845062)
- Where
- France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Montpellier
Obstructive Sleep Apnea
Combinations of Oral Appliance and CPAP for Patients With Severe Obstructive Sleep Apnea Untolerate High-pressure CPAP
Obstructive sleep apnea (OSA) is a situation of repetitive upper airway obstruction during sleep. For patients with severe OSA, continuous positive airway pressure (CPAP) therapy was the standard therapy, especially those with…
- Trial name
- NCT02217397
- Testing
- OA, CPAP, combination therapy
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Sleep Apnea
Long-term Effect of the Physical Activity Promotion on the Clinical Characteristics and Vascular Risk in Patients With Mild-moderate Obstructive Sleep Apnea
Main objective: To assess the effect of the daily physical activity promotion with a pedometer during 12 months on the apnea-hypopnea index (AHI) in patients with mild to moderate obstructive sleep apnea (OSA). Study patients.
- Trial name
- PASOS (NCT03086850)
- Testing
- Promotion of daily physical activity with a pedometer, Conventional treatment
- Where
- Spain
- Volunteers
- 144 people
- Sponsor
- Hospital Universitario La Paz
Obstructive Sleep Apnea, Cognitive Impairment
Cognitive Function and Quality of Life in Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA) is a common condition that disrupts normal breathing during sleep. Beyond causing daytime tiredness, OSA can also impact a person's cognitive functions, such as their attention span, memory, and…
- Conditions
- Obstructive Sleep Apnea, Cognitive Impairment, Quality of Life
- Trial name
- NCT07678918
- Volunteers
- 86 people
- Sponsor
- Assiut University
Obstructive Sleep Apnea
Dilator Muscle Activity in Health and Sleep Apnea
The role of control of peri-pharyngeal muscle tone in the pathogenesis of obstructive sleep apnea (OSA) is obvious: pharyngeal obstruction occurs only during sleep; and pharyngeal collapse occurs in almost all healthy subjects…
- Trial name
- NCT04254341
- Testing
- patients with OSA
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Obstructive Sleep Apnea, Obesity
Lifestyle Modification Using an App in OSA
This study aimed to investigate the effects of a mobile phone app linked to hospital electronic medical record (EMR) system on weight reduction and obstructive sleep apnea (OSA).
- Trial name
- NCT03189940
- Testing
- Life style modification by using and app with a wrist-worn activity tracker, Conventional Life style modification
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.