Clinical trials: OSAS
Positional Obstructive Sleep Apnea
Economic Evaluation of Treatment Modalities for Position Dependent Obstructive Sleep Apnea
OBJECTIVES: To evaluate the effect and cost-utility of a combination therapy of SPT+MAD compared with continuous positive airway pressure (CPAP) in patients with moderate positional obstructive sleep apnea (POSA).
- Trial name
- NCT02553902
- Testing
- Sleep position trainer, Mandibular advancement device, Continuous positive airway pressure
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 200 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Obstructive Sleep Apnea
The Association Between Obstructive Sleep Apnea Severity and Red Blood Cells Indices
Obstructive sleep apnea syndrome (OSAS) is characterized by recurrent episodes of obstructive events (apnea and hypopnea) and intermittent hypoxia, which in turn contributes to the systemic inflammation that underlies this…
- Trial name
- NCT06265129
- Testing
- Complete blood picture (done in the morning after the night of monitored sleep by PSG. With stress on red blood cell indices (RBC count, MCV, MCH, RDW)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Locally Advanced Head and Neck Squamous Cell Carcinoma, Metastatic Head and Neck Squamous Cell Carcinoma
Home Sleep Apnea Machine in Evaluating Obstructive Sleep Apnea in Patients With Stage III-IV Head and Neck Cancer
This trial studies information from a home sleep apnea machine to evaluate obstructive sleep apnea in patients with stage III-IV head and neck cancer.
- Trial name
- NCT03875053
- Testing
- Monitoring Device, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Sleep Apnea, Dyslipidaemia
Effect of Nasal CPAP on Lipid Profile in Patients With Dyslipidaemia and Sleep Apnea
OBJECTIVES Main objective: To assess if six months of treatment with CPAP, associated with conventional treatment, improves the lipid profile of patients with dyslipidemia and mild-moderate apnea-hypopnea syndrome (OSA).
- Trial name
- NCT02557412
- Testing
- Continuous positive airway pressure, Intensive lifestyle intervention, Conventional treatment
- Where
- Spain
- Sponsor
- Hospital Universitario La Paz
Obstructive Sleep Apnea Syndrome
Systemic Inflammation and Obstructive Sleep Apnea Syndrome: Effect of Atorvastatin
The aim of this clinical trial is to evaluate the effect of Atorvastatin on the endothelial function improvement during the obstructive sleep apnea syndrome (OSAS) after 3 months of treatment, by a double-blind, randomized…
- Trial name
- StatinflaSAS (NCT00669695)
- Testing
- Atorvastatin treatment, CPAP device
- Where
- 4 sites in France, Switzerland
- Volunteers
- 54 people
- Sponsor
- University Hospital, Grenoble
Sleepiness, SARS-CoV2 Infection
Obstructive Sleep Apnoea Post Covid 19: Role of the Upper Airway Microbiome
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causing coronavirus disease, Covid-19, has spread rapidly across the globe since its emergence in January 2020.
- Conditions
- Sleepiness, SARS-CoV2 Infection, Fatigue Syndrome, Chronic, Snoring
- Trial name
- NCT05116657
- Testing
- Nasal Lavage and Oral Wash
- Volunteers
- 50 people
- Sponsor
- Royal College of Surgeons, Ireland
Obstructive Sleep Apnea
Comprehensive Analysis of Respiratory Events Using Smartphone Systems
Earlier studies suggest that acoustical analysis of snoring sounds can identify obstructive sleep apnea (OSA). The goal of the current study is to refine and validate algorithms for OSA diagnosis.
- Trial name
- CARESS (NCT03457428)
- Where
- 4 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Resonea, Inc
Asthma, OSA
The Role of Endothelium A and EGFR Receptor in Fibrocytes From Asthma With Obstructive Sleep Apnea
The investigators will compare the circulating fibrocyte proportion in asthmatic patients with obstructive sleep apnea (OSA) and not with OSA In addition, the investigators will compare the expression of epidermal growth factor…
- Trial name
- NCT02749565
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Sleep Apnea, Obstructive
Effect of CPAP Treatment in Elderly: Randomized Clinical Trial
Rationale: Almost all the information the investigators have about the effect of continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) comes from randomized clinical trials including only…
- Trial name
- NCT02069600
- Testing
- Continuous Positive Airway Pressure
- Where
- Spain
- Volunteers
- 224 people
- Sponsor
- Hospital Universitario La Fe
Narcolepsy, Sleep Apnea, Obstructive
Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder
The primary objective of this study is to evaluate the safety and tolerability of Armodafinil (CEP-10953) administered on a flexible-dosage regimen of 100 to 250 mg/day for up to 12 months to patients with excessive sleepiness…
- Conditions
- Narcolepsy, Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Shift-Work Sleep Disorder
- Trial name
- NCT00078312
- Testing
- CEP-10953 (Armodafinil)
- Where
- 50 sites in United States, Russia
- Volunteers
- 328 people
- Sponsor
- Cephalon
Sleep Apnea, Obstructive
Titration Pressures in Sleep Apnea Patients Using ThermoSmart® Versus Conventional Humidification
Patients who have Obstructive Sleep Apnea (OSA) may have different Continuous Positive Airway Pressure (CPAP)when titrated with different levels of humidification.
- Trial name
- NCT00681083
- Testing
- Heated breathing tube (CPAP with ThermoSmart), Non heated breathing tube (CPAP with conventional humidification)
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Obstructive Sleep Apnea and Comprehensive Remotely-supervised Rehabilitation Program
The purpose of this study is to investigate the feasibility and effect of a 12-week remotely-supervised rehabilitation program in male patients between 25-65 years old with newly diagnosed obstructive sleep apnea with…
- Trial name
- NCT04759456
- Testing
- Remotely-supervised rehabilitation program
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Brno University Hospital
Obstructive Sleep Apnea
Promoting the Use of CPAP Therapy Among OSA Patients
Obstructive sleep apnea (OSA) is the most common sleep breathing disorder in the U.S. Continuous Positive Airway Pressure (CPAP) therapy is the most effective treatment for OSA.
- Trial name
- NCT04372329
- Testing
- CPAP4HealthySleep system
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Sarah Alismail
Obstructive Sleep Apnea
Promoting Adherence to Sleep Apnea Treatment Among Blacks With Metabolic Syndrome
This is a randomized controlled Trial to evaluate effect of a culturally and linguistically tailored, telephone-delivered behavioral intervention on adherence to recommended assessment and treatment of sleep apnea in Blacks with…
- Trial name
- MetSO (NCT01946659)
- Testing
- Adherence to Sleep Apnea Treatment, Standard Care Group
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- NYU Langone Health
Obstructive Sleep Apnea, Telemedicine
Global Self-management Telematic Support for Patients With Obstructive Sleep Apnea.
This clinical trial compares the usual follow-up to a program of telematic control and self-management in a group of patients with severe obstructive sleep apnea-hypopnea syndrome (OSAHS), few symptoms and treated with continuous…
- Conditions
- Obstructive Sleep Apnea, Telemedicine, Compliance, Patient
- Trial name
- TELESAS (NCT03792880)
- Testing
- Telematic control and self-management program, Habitual follow-up in Healthcare System
- Where
- 2 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Virgen del Puerto Hospital
Obstructive Sleep Apnea
Knowledge, Attitude, and Practice of Pediatric Dentists Toward Obstructive Sleep Apnea Among Children
The main objective of this study is to assess the knowledge, attitude, and practice of Egyptian pediatric dentists toward obstructive sleep apnea among children.
- Trial name
- NCT06970873
- Testing
- Evaluation of Knowledge, Attitude, and Practice of Pediatric Dentists
- Volunteers
- 362 people
- Sponsor
- Cairo University
Apnea, Obstructive Sleep, Pregnancy Complications
Sleep Apnea Syndrome in Obese Women During Pregnancy
Excess weight or obesity is associated with an increased risk of health disorders: high blood pressure, diabetes, cardiovascular risks, dyslipidemia and sleep apneas.
- Conditions
- Apnea, Obstructive Sleep, Pregnancy Complications, Pre-Eclampsia, Obesity
- Trial name
- NCT03509805
- Testing
- polysomnography
- Where
- France
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Obstructive Sleep Apnea
OSA in Children Referred for Adenotonsillectomy
In children with OSA (Obstructive sleep apnea) adenotonsillectomy is regarded as the first choice of treatment. Studies in recent years have shown that the procedure does not always have the expected effect.
- Trial name
- NCT02233166
- Where
- Norway
- Volunteers
- 115 people
- Sponsor
- Lovisenberg Diakonale Hospital
Lysosomal Storage Disease, Lung Diseases
Biomarker for Maroteaux-Lamy Disease (BioMaroteaux)
Development of a new MS-based biomarker for the early and sensitive diagnosis of Maroteaux-Lamy disease from blood
- Conditions
- Lysosomal Storage Disease, Lung Diseases, Obstructive Sleep Apnoea, Macroglossia
- Trial name
- BioMaroteaux (NCT01458613)
- Where
- 5 sites in Egypt, Germany and 2 more
- Sponsor
- CENTOGENE GmbH Rostock
Obstructive Sleep Apnea, Excessive Sleepiness
Study Assessing Effects of JZP-110 on Driving Performance in the Treatment of Excessive Sleepiness in OSA
This trial is a randomized, double-blind, placebo-controlled, crossover study to evaluate the effect of JZP-110 on driving performance in subjects with excessive sleepiness due to obstructive sleep apnea.
- Trial name
- NCT02806895
- Testing
- JZP-110
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Jazz Pharmaceuticals
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