Clinical trials: Obese Children and Adolescents
Overweight, Obesity
Effects of Intermittent Caloric Restriction in Youth With Cardiometabolic Risk
This is a randomized controlled pilot study to evaluate the effects of intermittent caloric restriction compared with low carbohydrate diet in youth with cardiometabolic risk.
- Conditions
- Overweight, Obesity, Cardiometabolic Risk
- Trial name
- NCT04011995
- Testing
- Intermittent caloric restriction, Low carbohydrate diet, Health education on reducing the cardiometabolic risk
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Children's Hospital of Fudan University
Binge Eating Disorder, Binge Eating
Effectiveness of a 10-week Multicomponent Intervention Combined With Parent Education on Binge Eating Behavior in Children and Adolescents
The main purpose is to investigate the effectiveness of a 10-week multicomponent camp intervention to reduce BE behavior in children and adolescents and explore in a randomized controlled setting if a parent-based…
- Conditions
- Binge Eating Disorder, Binge Eating, Loss of Control Eating, Overweight , Obesity
- Trial name
- STOB (NCT07301541)
- Testing
- A 10-week multicomponent camp intervention for children, A BED intervention for parents
- Where
- 2 sites in Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Neurodevelopmental Disorders, Irritability
AP Metabolism Transcriptomics
It is known from the literature that treatment with antipsychotic drugs (AP) induces, even before changes in blood chemistry parameters, changes in gene transcription that are evident at the level of peripheral blood mononuclear…
- Trial name
- NCT06814314
- Testing
- Transcriptomic investigation
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Eugenio Medea
Adolescent, Pediatric Obesity
Controlled Evaluation of an Exercise Program for Overweight Adolescents
Physical activity decreases as young people get older, especially during the shift from early to late adolescence. Unfortunately, around 81% of school-aged children worldwide between the ages of 11 and 17 do not meet the…
- Conditions
- Adolescent, Pediatric Obesity, Exercise Therapy, Health Promotion
- Trial name
- Now! (NCT06923865)
- Testing
- training group
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University Hospital, Basel, Switzerland
Childhood Obesity
Leipzig Childhood Obesity Study
The aim of this study is to identify polymorphisms that make children and adolescents more prone to obesity and metabolic dysfunction, as well as to identify biomarkers that are linked to causes and consequences of obesity.
- Trial name
- NCT04491344
- Where
- Germany
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Autism Spectrum Disorder, Obesity
Semaglutide in Youth With Autism Spectrum Disorder
This study is a 6-month, two-arm, RCT which will evaluate the effectiveness and safety of semaglutide in adolescents aged 12-18 years with autism spectrum disorder (ASD) and obesity.
- Trial name
- GLP1 (NCT07770152)
- Testing
- Glucagon-like peptide-1 receptor agonist：Semaglutide, Lifestyle Management (LSM) Counseling
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obesity
Managing Patient Expectations in Pediatric Weight Management
As part of Children's Hospital Association's Focus on a Fitter Future III Obesity Task Force, this project will target patient and family expectations across the domains of nutrition, physical activity and behavior change/family…
- Trial name
- NCT01753063
- Testing
- Patient Expectations
- Where
- 12 sites in United States
- Volunteers
- 405 people
- Sponsor
- Boston Children's Hospital
Obesity, Childhood
Evaluating a Telemedicine-based Intensive Treatment Program for Children and Adolescents With Obesity
The study objective is to evaluate whether a novel telemedicine-based intensive treatment program for children with obesity is superior to standard on-site care.
- Trial name
- NCT05700409
- Testing
- Intensive lifestyle consultations
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Obesity, Adolescent, Adolescent Behavior
Study of Nutrition and Activity in Kids
While a substantial body of research suggests that RRV is related to obesity, there is very little research on factors that contribute to the RRV of food, particularly how patterns of eating can increase or decrease the…
- Trial name
- SNAK (NCT04027608)
- Testing
- Reinforcing value of HED and LED foods in response to snack food monotony
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Adolescents, Mobile Application
The Effect of Mobile Application Supported Health Promotion Program on Obesity of Adolescents
The aim of the study is to evaluate the effectiveness of the Child Obesity Program (COP), which is a school-based, parent-based, weight management program aimed mobile application at preventing overweight and obesity in childhood.
- Conditions
- Adolescents, Mobile Application, School Health, Physical Activity
- Trial name
- obesity (NCT06427525)
- Testing
- Mobile application-based adolecent obesity education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Hepatic Steatosis, Fatty Liver
Hepatic De Novo Lipogenesis (DNL)in the Pathogenesis of Hepatic Steatosis in Obese Youth
Nonalcoholic Fatty Liver Disease (NAFLD) is becoming the most common cause of liver disease in pediatrics, but little is known about its pathophysiology in children.
- Trial name
- DNL (NCT01725035)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Obesity, Childhood
Acetaminophen Dosing in Obese Adolescents
Although there are numerous studies investigating the pharmacokinetic properties of intravenous acetaminophen in infants and children with normal weight, there are none in the obese pediatric patient .
- Trial name
- NCT03192566
- Testing
- Tylenol
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Obesity Prevention, Pediatric Obesity
Relationship Between Eating Patterns, Body Composition and the Detection of Fatty Liver in Children and Adolescents With Trisomy 21: LiverTy Project
Childhood obesity is a growing public health issue affecting millions of children worldwide, increasing the risk of metabolic and cardiovascular diseases in adulthood.
- Conditions
- Obesity Prevention, Pediatric Obesity, Trisomy 21, Down Syndrome (Trisomy 21)
- Trial name
- LiverTy (NCT06888570)
- Testing
- To evaluate fat liver content in the cases/controls population.
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- IMDEA Food
Childhood Obesity, Overweight (BMI > 25)
Weight Status, Resilience, and Quality of Life in Indian Children
A school-based cross-sectional study that aims to generate context-specific evidence on how weight status is related to resilience, health behaviour, and quality of life among Indian adolescents.
- Conditions
- Childhood Obesity, Overweight (BMI > 25), Underweight
- Trial name
- NCT05648045
- Where
- 16 sites in India
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Metabolic Dysfunction-Associated Steatotic Liver Disease, Childhood Obesity
Lifestyle Habits and Metabolic Dysfunction-Associated Steatotic Liver Disease in Youth
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is the most common cause of chronic liver disease in children and adolescents.
- Trial name
- LIFE4MASLD (NCT07095010)
- Where
- Greece
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Pediatric Obesity
A National School-based Health Lifestyles Interventions Among Chinese Children and Adolescents Against Obesity
The study was designed as a national multi-centered cluster randomized controlled trial involving more than 70,000 children and adolescents aged 7-18 years from 7 provinces in China.
- Trial name
- NCT02343588
- Testing
- The Health Lifestyles Interventions
- Volunteers
- 70,000 people
- Sponsor
- Sun Yat-sen University
Obesity and Overweight, Obese Adolescents
Mitigation of Cardiovascular Disease Risks in Children With Extreme Obesity
The goal of this clinical trial is to learn if the drug semaglutide changes markers of disease risk as it relates to weight in children ages 12-15 years old who are obese (class 2 or 3).
- Conditions
- Obesity and Overweight, Obese Adolescents, Weight Management, Weight Loss
- Trial name
- MODERN (NCT06967389)
- Testing
- Ozempic®
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- John Bauer
Obesity
Multidisciplinary Ambulatory Intervention Program in Family of Children and Adolescents With Obesity
Obesity has become a pandemic, and it is today's principal neglected public health problem. Obesity has increased dramatically during the past two decades At adolescence, it is an aggravating issue, because obesity tends to…
- Trial name
- NCT00344747
- Testing
- dietary, behavioral, physical activity
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Soroka University Medical Center
Overweight (BMI > 25)
Prevent and Reverse Obesity in Children, Adolescents and Young Adults
Obesity and overweight are non-communicable diseases with an increasing incidence in children, adolescents, and adults. International efforts to reverse the current epidemiological trend of rising overweight, obesity, and related…
- Trial name
- PasGras (NCT07035704)
- Testing
- MeD enriched with mushrooms, MeD enriched the Lebanese herbal mixture Za'atar, MeD Diet + semaglutinine or compatible treatment+ Za'atar or Mushroom (to be defined)
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- piero portincasa
Exercise Condition (EX), Control Session (CON)
Exercise and Neural Response to Food Cues in Children
Physical exercise has been shown to significantly reduce subsequent energy intake in obese adolescents but not in lean, without altering their appetite feelings.
- Trial name
- NCT02100878
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Université Blaise Pascal, Clermont-Ferrand