Clinical trials: Obese Diabetics
Diabetes
Investigation Into the Effects of Blood Glucose Levels Upon Eating Behavior in Lean and Obese Non-diabetic and Diabetic Subjects
To investigate whether the daily glucose profiles as assessed by continuous glucose monitoring for 1 week of normal weight and obese individuals relate to hunger levels and food intake.
- Trial name
- NCT02673203
- Testing
- Continuous Glucose Monitoring System (CGMS), Food log
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Yale University
Diabetes Mellitus, Type 2, Obesity
Pharmacodynamic Study of the Effect of INCB013739 on Insulin Sensitivity in Obese, Type 2 Diabetic Subjects
Purpose: A 28-day US study in patients with type 2 diabetes mellitus to assess the safety and tolerability as well as the effects of treatment with an investigational drug.
- Trial name
- NCT00478322
- Testing
- INCB013739
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Incyte Corporation
Healthy, Non-diabetic Overweight or Obese
A Study of BGM0504 Tablets in Healthy and Non-diabetic Overweight or Obese Chinese Subjects
A Randomized, Double-Blind, Placebo-Controlled, Single/Multiple-dose Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of BGM0504 Tablets Orally Administered in Healthy and Non-diabetic Overweight or Obese…
- Trial name
- NCT07239973
- Testing
- BGM0504 tablets
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- BrightGene Bio-Medical Technology Co., Ltd.
Diabetes, Diabetes Mellitus, Type 1
Observational Study on Levemir® in Obese Diabetic Patients
This study is conducted in Europe. The aim of this observational study is to investigate the effect of switch from other basal insulin treatments to Levemir® on body weight in obese diabetic patients.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- KILOS (NCT00849342)
- Testing
- insulin detemir
- Where
- 2 sites in Netherlands, Slovenia
- Volunteers
- 580 people
- Sponsor
- Novo Nordisk A/S
Obesity, Type2 Diabetes
Impact of Plasma Soluble Prorenin Receptor in Obese and Type 2 Diabetic Patients
Obesity increases the risk for type 2 diabetes mellitus, high blood pressure, and mortality. Obesity is a major health problem in the United States, especially in the Deep South regions.
- Conditions
- Obesity, Type2 Diabetes, Bariatric Surgery Candidate
- Trial name
- NCT03643783
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Tulane University
Health Care Delivery
All-encompassing Program Led by Diabetes Specialist Team
Obese type 2 diabetic patients are difficult to treat with many unmet needs requiring complex treatment regimens, intensive counselling and emotional support.
- Trial name
- EMERALD (NCT03497390)
- Testing
- EMERALD intervention, Usual care
- Where
- China
- Volunteers
- 207 people
- Sponsor
- Chinese University of Hong Kong
Type 2 Diabetes, Obesity
Effect of Discontinuation of Sugar Sweetened Beverages
Purpose The purpose of this study is to investigate the effects of discontinuation of sugar sweetened beverages on hemoglobin A1c (HbA1c) and plasma fasting and post-prandial blood glucose in a population with type 2 diabetes.
- Trial name
- NCT00585897
- Testing
- discontinuation of sugar sweetened beverages
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Diabetes Mellitus, Type 2
Effect of a Postbiotic Intake on Glucose Control and Microbiota Composition of Type 2 Diabetic Subjects: a Randomized Controlled Trial.
The goal of this randomized clinical trial is to evaluate the effect of the administration of a postbiotic on glycemic control, insulin resistance and microbiota composition in subjects with type 2 diabetes.
- Trial name
- Diabet2Predict (NCT06448182)
- Testing
- Postbiotic
- Where
- 3 sites in Spain
- Volunteers
- 106 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Type 2 Diabetes, Obesity
Research on Effects of Acute Consumption of Nuts in Obese Diabetic Women
Obesity is a multifactorial disease in which excess body fat accumulation increases the risk of other chronic diseases such as type 2 diabetes.
- Trial name
- REACT-NUT (NCT06710340)
- Testing
- Nuts in the first meeting, Nuts in the second meeting
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Raquel Ballarin
Non-diabetic Overweight or Obese
Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BGM0504 Tablets in Non-diabetic Overweight or Obese Adult Subjects
This is a Phase 1, single-center, randomized, placebo-controlled, ascending dose study. The study will evaluate the pharmacokinetics (PK), pharmacodynamic (PD), preliminary efficacy, safety and tolerability of BGM0504 following…
- Trial name
- NCT07166081
- Testing
- BGM0504
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- BrightGene Bio-Medical Technology Co., Ltd.
Type 2 Diabetes Mellitus, Obesity
Effects of Rosiglitazone on Bone in Postmenopausal Diabetic Women
The purpose of this study is to evaluate the effect of rosiglitazone on bone metabolism and to assess the association between the changes in bone turnover parameters and plasma cytokine levels in postmenopausal diabetic women
- Conditions
- Type 2 Diabetes Mellitus, Obesity, Menopause
- Trial name
- NCT00440375
- Testing
- Rosiglitazone
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Baskent University
Weight Management, Treatment Of Obesity
A Trial In Diabetic Patients To Assess Effect Of CE-326,597 On Glucose Control And Body Weight
Study of whether the investigational drug CE-326,597 improves glucose control and results in body weight loss in patients with type 2 diabetes
- Trial name
- NCT00542009
- Testing
- CE-326,597 100 mg QD, CE-326,597 50 mg QD, CE-326,597 25 mg QD
- Where
- 54 sites in United States, Bulgaria and 5 more
- Volunteers
- 252 people
- Sponsor
- Pfizer
Cardiovascular Diseases, Diabete Type 2
EffectiVenEss of a Rehabilitation Treatment With Nordic Walking in obEse or oveRweight Patients
Nordic Walking (NW) is a biomechanically correct walking technique that originated in Finland in the 1930s as an off-season training method for cross-country skiers.
- Conditions
- Cardiovascular Diseases, Diabete Type 2, Overweight and Obesity
- Trial name
- VENERE (NCT05987410)
- Testing
- Nordic Walking (NW), Standard Rehabilitation (SR), Cardiological Counselling (CC)
- Where
- Italy
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Obesity, Diabetes Mellitus, Type 2
Systemic Metabolic Rate of Diabetic Patients Before and After Bariatric Gastric Bypass Using the Breezing® Device.
To evaluate the systemic metabolic rate of diabetic patients before and after bariatric gastric bypass surgery using the Breezing® device.
- Trial name
- NCT05505773
- Volunteers
- 200 people
- Sponsor
- Kaiser Clinic and Hospital
Obesity and Cardiovascular Risk, Insulin Resistance
Effect of Metformin Use on Weight Loss in Obese, Non-diabetic People (MOWRI)
Obesity is a chronic disease of global public health concern, contributing to cardiovascular disease, type 2 diabetes and certain cancers.
- Conditions
- Obesity and Cardiovascular Risk, Insulin Resistance, Obesity (Body Mass Index >30 kg/m2)
- Trial name
- MOWRI (NCT07297290)
- Testing
- Metformin
- Where
- 2 sites in Nigeria
- Volunteers
- 220 people
- Sponsor
- University Of Nigeria Teaching Hospital
Overweight, Obesity
Effects of a Wholegrain Diet on Body Composition and Energy Balance
The purpose of this study is to compare a diet containing whole grains versus an energy matched diet using refined grains on body composition and metabolism.
- Conditions
- Overweight, Obesity, Pre-diabetic
- Trial name
- NCT01411540
- Testing
- Whole grains
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Adenocarcinoma of the Endometrium
A Randomized Pilot Study to Evaluate the Effects of a Short Course of Metformin Versus No Therapy in the Period Prior to Hysterectomy for Grade 1-2 Adenocarcinoma of the Endometrium in Obese Non-Diabetic Women
The purpose of this research is to determine the effects of Metformin, a well tolerated drug widely prescribed for treatment of Type 2 Diabetes Mellitus, on endometrium cancer patients.
- Trial name
- NCT01877564
- Testing
- Metformin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Arkansas
Obesity
Weight Loss in Pre-diabetic, Obese Women
This is a six (6) month, single center, randomized, double-blind, parallel, controlled-feeding weight-loss study comparing two dietary groups (triglyceride and olestra) in pre-diabetic obese women.
- Trial name
- NCT00686816
- Testing
- Low calorie diet, Olestra
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Procter and Gamble
Healthy, Obesity
Metabolic Phenotyping in Humans
Type 2 diabetes (T2D) is a global burden disease affecting almost 200 million people and is expected to nearly double by 2030 (1).
- Conditions
- Healthy, Obesity, Type 2 Diabetes Mellitus
- Trial name
- MetPhe (NCT01298375)
- Where
- Netherlands
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Diabetes Mellitus
Plantar Faciitis and Diabetes Mellitus
Obesity is a risk factor for calcaneal spur (CS) formation which is supposed to originate from chronic plantar fasciitis. Diabetes mellitus may contribute to the risk of CS by decreased ability of tissue repair and increased…
- Trial name
- No acronym (NCT01259206)
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine