Clinical trials: Obese Patients With Bariatric Surgery
Obesity, GHD
Replacement GH Therapy After Bariatric Surgery in Patients With Very Severe Obesity
Obesity and obesity-related diseases have reached epidemic proportions in Western countries (1-3). Laparoscopic-adjustable silicone gastric banding (LASGB) is a purely restrictive operation that determine effective weight loss…
- Trial name
- GH&LASGB (NCT00553852)
- Testing
- Recombinant GH Saizen (Merck-Serono)
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Federico II University
Obesity, Weight Loss
Research on Timing of Liraglutide Therapy in Patients With Obesity After Metabolic Surgery
The goal of this clinical trial is to compare the weight loss and metabolic benefit in patients remaining obesity at 6 months after metabolic surgery.
- Conditions
- Obesity, Weight Loss, Bariatric Surgery
- Trial name
- NCT07374445
- Testing
- Liraglutide injection, Diet and exercise guidelines
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Obstructive Sleep Apnea, Obesity
Comparison of Apnea-Hypopnea Index in Patients With or Without Preventive Oxygen Therapy After Bariatric Surgery
The best perioperative strategy for obstructive sleep apnea (OSA) in bariatric surgery remains unclear. A strategy is to monitor patients and administer preventive oxygen therapy during the first postoperative night.
- Conditions
- Obstructive Sleep Apnea, Obesity, Bariatric Surgery Candidate
- Trial name
- OXYBAR (NCT06432933)
- Testing
- No preventive oxygen therapy (2L), Preventive oxygen therapy (2L) standard care
- Where
- Netherlands
- Volunteers
- 153 people
- Sponsor
- Rijnstate Hospital
Obesity, Bariatric Surgery Candidate
Diet-induced Thermogenesis in Patients With Postoperative Roux-in-Y Gastric Bypass (RYGBP) Weight Regain
Introduction: According to the National Health and Nutrition Examination Survey 2009-2010, 78 million American adults are obese.
- Conditions
- Obesity, Bariatric Surgery Candidate, Protein-energy; Imbalance
- Trial name
- RYGBP (NCT02422212)
- Testing
- patients eat a mixed solid meal
- Where
- 3 sites in Brazil
- Volunteers
- 45 people
- Sponsor
- Silvia Leite Faria
Obesity
Roux-en-Y Gastric Bypass: Clinical Trial
The present study aims to describe the results of a modified gastric bypass surgery to ensure endoscopic access to the excluded remaining stomach, as well as to monitor the clinical conditions of comorbidities and the patient's…
- Trial name
- ERAPT (NCT04649619)
- Testing
- GASTRIC BYPASS MODIFIED IN ROUX-EN-Y AS A THERAPEUTIC OPTION IN PATIENTS WITH INDICATION OF BARIATRIC AND / OR METABOLIC SURGERY
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Paulo Reis Esselin de Melo
Postoperative Pain Relief
Bilateral Thorathic Erector Spinae Plane Block in Laparoscopic Bariatic Surgeries
The study is to evaluate effectiveness of one-level versus two-level thoracic ESP block on intraoperative and postoperative analgesia in bariatric surgeries and to compare total opioid consumption of both groups.
- Trial name
- ESPBbariatrics (NCT06812364)
- Testing
- one level ESPB, two level ESPB
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Morbid Obesity D009765
Preoperative Omega-3 Polyunsaturated Fatty Acids in Morbidly Obese to Reduce Liver Volume and Steatosis
Hepatomegaly is common in the morbidly obese patients and it may hamper the access to the hiatal region during bariatric surgery.
- Trial name
- Omegobese (NCT03006016)
- Testing
- Omega-3 Fatty Acid
- Where
- 2 sites in France
- Volunteers
- 44 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Overweight, Type 2 Diabetes
Quantitative and Qualitative MRI Study of Steatosis in Patients With Metabolic Steatopathy
This is a single centre prospective open-label, non-randomised pilot study whose aim is to identify MRI parameters to better evaluate inflammation and liver fibrosis and thus, in the near future, to avoid the need for liver…
- Conditions
- Overweight, Type 2 Diabetes, Obesity
- Trial name
- IRM Stéatose (NCT02085876)
- Testing
- 2 additional MRI sequences, An additional blood sample
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Anesthesia, Obesity
Effects of Anesthesia With Propofol Versus Desflurane in Obese Patients
Evaluate the effects of propofol compared with desflurane on oxidative stress and inflammation markers in obese patients undergoing scheduled bariatric surgery.
- Trial name
- NCT03417518
- Testing
- Desflurane Inhalant Product, Propofol
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Obese Patients, Bariatric Surgical Pain
Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy
Regional anesthesia is a technique in which a local anesthetic is injected near a nerve or spinal cord to block sensation, motor stimulation, and pain.
- Conditions
- Obese Patients, Bariatric Surgical Pain, Bariatric Surgery (Sleeve Gastrectomy ), Non-Opioid Pain Management
- Trial name
- NCT07084753
- Testing
- Levobupivacaine, Dexamethasone contained in the solution for thoracic paravertebral block, Adrenaline
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- IVO JURISIC
Diabetes Mellitus, Obesity
Single Loop DJB Sleeve Gastrectomy for Poorly Controlled T2DM
Type 2 diabetes mellitus (T2DM) is a chronic progressive illness affecting a substantial percentage of the general population. While pharmacotherapy remains the mainstay of treatment, around 60% of patients cannot achieve the…
- Conditions
- Diabetes Mellitus, Obesity, Bariatric Surgery Candidate, Weight Loss
- Trial name
- NCT03125369
- Testing
- Sleeve gastrectomy + duodeno-jejunal bypass, Roux-Y gastric bypass
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Obesity, Hypertension
Hemodynamics, Salt Sensitivity and Body Composition in Patients With Morbid Obesity
The purpose of this study is to evaluate the effect of high vs. low sodium intake on blood pressure and system hemodynamics in patients with morbid obesity and to evaluate the impact of laparoscopic gastric bypass on blood…
- Trial name
- NCT00998465
- Testing
- 24-hour blood pressure, Echocardiography, Inert gas rebreathing
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Type I Diabetes
Obesity and Metabolic Surgery in Patients With Type I Diabetes
Obesity is the indication for bariatric surgery in type I diabetes. Interestingly postsurgery the patients improve remarkable in their need for insulin, not only in the daily total insulin dosage but also in the dosage of IU per…
- Trial name
- NCT02612493
- Testing
- Obese patients with type I diabetes
- Volunteers
- 16 people
- Sponsor
- Sana Klinikum Offenbach
Clinically Severe Obesity, Inadequate Weight Loss
Laparoscopic Revision of Vertical Banded Gastroplasty to Gastric Bypass
The main aim of this study is to analyze and report the intermediate term outcomes after laparoscopic revision Roux-en-Y gastric bypass (RYGB) surgery for failed and/or complicated Vertical Banded Gastroplasty (VBG).
- Conditions
- Clinically Severe Obesity, Inadequate Weight Loss, Obesity Recidivism
- Trial name
- VBG (NCT01041131)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Francisco
Obesity, Morbid, Anal Incontinence
Impact of Bariatric Surgery in Patients With Morbid Obesity
The main objective is to compare the prevalence of anal incontinence (AI) before and after bariatric surgery in obese patients. Inclusion: Patients who are scheduled for a bariatric surgical procedure after a multidisciplinary…
- Conditions
- Obesity, Morbid, Anal Incontinence, Image, Body
- Trial name
- IVBIA (NCT04009356)
- Testing
- bariatric surgical procedures
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Central Hospital, Nancy, France
Obesity, Morbid
Impact of Size of Gastric Sleeve on the Weight Loss. Correlation With Gastric Function and Endocrine-metabolic Changes.
Morbid Obesity (MO) is considered the most important epidemic in the developed world in the twenty-first century. After initial assessment of morbidly obese patients and the exclusion of potentially correctable causes, management…
- Trial name
- NCT02144545
- Testing
- Bougie Size 33 Fr, Bougie Size 42 Fr, Distance pylorus 2 cm
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Obesity, Bariatric Surgery Candidate
Crural Repair During Laparoscopic Sleeve Gastrectomy in Patients With a Lax Gastroesophageal Junction
Background: Laparoscopic sleeve gastrectomy (LSG) is one of the commonest bariatric procedures. However, it is associated with postoperative gastroesophageal reflux disease (GERD) and erosive esophagitis (EE).
- Conditions
- Obesity, Bariatric Surgery Candidate, Esophagus Injury, Gastroesophageal Reflux
- Trial name
- REPAIR (NCT05330910)
- Testing
- Laparoscopic sleeve gastrectomy with concomitant hiatal hernia repair arm, Laparoscopic sleeve gastrectomy arm
- Where
- 2 sites in Singapore
- Volunteers
- 96 people
- Sponsor
- Sengkang General Hospital
Morbid Obesity, Opioid-Related Disorders
Recovery of Ventilation After General Anesthesia in Morbidly Obese Patients
This is an observational study of morbidly obese patients recovering from general anesthesia after weight-loss surgery. The investigators aim to assess ventilatory function and how this is influenced by the diagnosis of…
- Conditions
- Morbid Obesity, Opioid-Related Disorders, Surgery--Complications, Sleep Apnea Syndromes
- Trial name
- NCT03925610
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Stanford University
Surgery, Post-operative Pain
Laparoscopic Single Incision -Vs- Multiple Incision Gastric Band Surgery
A double blinded randomised control trial comparing the differences between laparoscopic single incision versus multiple port bariatric surgery in morbidly obese patients (BMI>35).
- Conditions
- Surgery, Post-operative Pain, Post-operative Recovery
- Trial name
- SIMIS (NCT01844960)
- Testing
- Single Incision Gastric Band Insertion, Multiple Incision Gastric Band Insertion
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- King's College Hospital NHS Trust
Bariatric Surgery Candidate
The Link Between Obesity And Vitamin D in Bariatric Patients With Omega-loop Bypass Surgery
The aim of the study is to increase vitamin D concentrations or to keep it on high level, respectively, by supplementing with vitamin D3 in a different dose regime, and to improve the overall health status in bariatric patients.
- Trial name
- LOAD (NCT02092376)
- Testing
- Cholecalciferol
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Maria Luger