Clinical trials: Obese Pregnant Women
Obesity, Glomerulopathy
Dietary Intervention in Obesity-related Glomerulopathy
Obesity-related glomerulopathy (ORG) is a silent comorbidity associated with obesity whose incidence is increasing in parallel to the obesity epidemic.
- Trial name
- ORG-VLCD-2022 (NCT05294770)
- Testing
- Optisource® Plus: Very Low Calorie Diet treatment, Hypocaloric Mediterranean Diet
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Obesity & Overweight, Infertility, Female
Dietary Reversal of the Reprometabolic Syndrome
This study proposes to test the specific question that a eucaloric, low-fat diet given to women with obesity will result in an increase in reproductive hormones.
- Trial name
- LFD (NCT07227766)
- Testing
- Low-fat diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Polycystic Ovary Syndrome, Insulin Resistance
Auricular Acupressure (AA) For Insulin Resistance in Women With Polycystic Ovary Syndrome
The present trial is a pilot study to investigate the effect of auricular acupressure on insulin resistance in women with PCOS.A total of 100 subjects will be enrolled into this study and will be randomized into two groups.
- Trial name
- NCT03546595
- Testing
- Auricular acupoints acupressure
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Pregnant Women, Gestational Diabetes
Physical Acvitiy in Pregnancy
The goal of this observational study is to learn how a physically active lifestyle during pregnancy affects placental development and function.
- Conditions
- Pregnant Women, Gestational Diabetes, Obese But Otherwise Healthy Participants, Overweight (BMI > 25)
- Trial name
- NCT07356180
- Testing
- Pregnancy Physical Activity Questionnaire (PPAQ)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Maryland, Baltimore
Hypothalamic Obesity, Multiple Pituitary Hormone Deficiency Genetic Form
A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)
This is a sub-study of Study RM-493-040 (NCT05774756). The goal of this sub-study is to learn how well Setmelanotide works to improve weight reduction, hunger, and quality of life in patients 4 years of age and older with…
- Conditions
- Hypothalamic Obesity, Multiple Pituitary Hormone Deficiency Genetic Form, Septo-Optic Dysplasia, Optic Nerve Hypoplasia
- Trial name
- NCT06760546
- Testing
- Setmelanotide
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 39 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Renal Stone
Standard PCNL Vs Endoscopic Combined Intrarenal Surgery (ECIRS) for Complex Nephrolithiasis in Obese Patients
Primary aim: comparing the efficacy of standard PCNL and endoscopic combined intrarenal surgery (ECIRS) in the Galdakao-modified Supine Valdivia (GMSV) position in a single session for the treatment of complex nephrolithiasis in…
- Trial name
- ECIRS (NCT06085794)
- Testing
- Endoscopic combined intrarenal surgery, Percutaneous nephrolithotomy
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome, Obesity
Low Dose Liraglutide and Metformin vs. High Dose Liraglutide Alone in Treatment of Obesity
Weight reduction is the most important treatment target when polycystic ovary syndrome (PCOS) is linked to obesity. Liraglutide (LIRA) in dose of 3 mg was recently approved as an anti-obesity drug.
- Trial name
- NCT02909933
- Testing
- liraglutide, metformin and liraglutide
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Hypertension, Cardiovascular Disease
Population Based Strategies for Effective Control of High Blood Pressure in Pakistan
Studies have established that high blood pressure (BP) is the most common risk factor for cardiovascular disease (CVD). Despite a heavy burden of hypertension (33% of all persons aged 45 years and over), there are no reliable…
- Conditions
- Hypertension, Cardiovascular Disease, Obesity, Diabetes
- Trial name
- NCT00327574
- Testing
- Home heath education +/_ GP training
- Where
- Pakistan
- Sponsor
- Aga Khan University
Polycystic Ovary Syndrome
Intermittent Fasting Diet Versus Resistive Exercise Program on Insulin Resistance in Obese Women With P.C.O.S
This study will be carried out in an attempt to know which is more effective, Intermittent fasting diet or resistive exercise program on insulin resistance in obese woman with polycystic ovarian syndrome.
- Trial name
- NCT06882291
- Testing
- Intermittent fasting diet, Resistive exercise program, Medical treatment
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Type 2 Diabetes, Obesity
A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk
The main purpose of this study is to determine safety and efficacy of orforglipron compared with insulin glargine in participants with type 2 diabetes and obesity or overweight at increased cardiovascular risk.
- Conditions
- Type 2 Diabetes, Obesity, Overweight or Obesity, Overweight
- Trial name
- ACHIEVE-4 (NCT05803421)
- Testing
- Orforglipron, Insulin Glargine
- Where
- 358 sites in United States, Argentina and 14 more
- Volunteers
- 2,749 people
- Sponsor
- Eli Lilly and Company
Stress, Urinary
Laser Acupuncture and Pelvic Floor Training on Stress Urinary Incontinence Postmenopausal
This study will be directed to determine the effectiveness of laser acupuncture(LA) and pelvic floor training (PFT) on stress urinary incontinence (SUI) in obese postmenopausal women.
- Conditions
- Stress, Urinary, Incontinence
- Trial name
- NCT04959084
- Testing
- Laser acupuncture therapy and pelvic floor training
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Fetus Fetus, Pregnancy Complications
the Fetal Epicardial Thickness in Obese Pregnant Women (EFT)
the effects of fetal EFT on fetal cardiac function and fetal and maternal outcomes were investigated in obese pregnant women compared with normal-weight pregnant women.
- Trial name
- EFT (NCT05948319)
- Testing
- Doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Childhood Obesity, Maternal Obesity During Childbirth
Prenatal Probiotic Intervention
This study will assess the feasibility of a randomized control trial in which the effects of probiotic supplementation throughout pregnancy on maternal insulin sensitivity and inflammation, as well offspring gene expression and…
- Conditions
- Childhood Obesity, Maternal Obesity During Childbirth, Insulin Resistance, Inflammation
- Trial name
- NCT03240419
- Testing
- Probiotics
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Preeclampsia
Aspirin 150 mg vs 100 mg for Prevention of Preeclampsia in High-Risk Obese Pregnant Women
According to the American College of Obstetricians and Gynecologists (ACOG), pregnancy-induced hypertension is defined as a new onset of systolic and/or diastolic blood pressure ≥140/90 mmHg after 20 weeks of gestation, with at…
- Trial name
- NCT06952712
- Testing
- Aspirin 100mg, Aspirin 150mg
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- FANG HE
Obesity, Pregnancy Complications
NT-proBNP Levels and Obesity in Pregnancy
A screening modality to help categorize obese pregnant women as high or low probability for heart failure would be helpful in the evaluation of the obese pregnant women with dyspnea.
- Conditions
- Obesity, Pregnancy Complications, Peripartum Cardiomyopathy
- Trial name
- NCT04049136
- Testing
- NT-proBNP
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Duke University
Obesity in Pregnancy, Maternal Comfort During Fetal Monitoring
EFFECT OF DİFFERENT POSİTİONS ON PAİN AND COMFORT DURİNG FETAL MONİTORİNG İN OBESE PREGNANT WOMEN
This study was conducted to understand how different body positions during fetal monitoring affect pain and comfort in obese pregnant women.
- Trial name
- NCT07379307
- Testing
- Maternal Positioning during NST
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Endometrium Cancer, Life Style
Effect of a Lifestyle Intervention on Nutritional Status and Prognosis of Endometrial Cancer Survivors
The objective of the present study is to implement and evaluate the effect of a counseling program to promote healthy eating and practice of physical activity in the nutritional status, quality of life and prognosis of women Type…
- Conditions
- Endometrium Cancer, Life Style, Obesity
- Trial name
- NCT03095664
- Testing
- Intervention group
- Where
- Brazil
- Volunteers
- 286 people
- Sponsor
- Brazilian National Cancer Institute
Gestational Diabetes, Obesity
Randomizing Two Gestational Diabetes Screening Methods in a Diverse HMO
This project randomizes two different screening strategies for diabetes in pregnancy, among a study population of over 17,500 pregnant women and their babies (over 35,000 total) in a large diverse health maintenance organization…
- Conditions
- Gestational Diabetes, Obesity, Pregnancy
- Trial name
- NCT02266758
- Testing
- GDM Screening Methods
- Volunteers
- 23,792 people
- Sponsor
- Kaiser Permanente
Healthy Pregnant Women, Obese Pregnant Women
Pregnancy Cohort Study: Pregnancy as a Window to Future Health
The goal of this observational cohort study is to gain deep insights into how metabolic disorders such as obesity or diabetes during pregnancy affect the metabolic and cardiovascular health of mother and child in the short and…
- Conditions
- Healthy Pregnant Women, Obese Pregnant Women, Gestational Diabetes
- Trial name
- PregWin (NCT06925815)
- Where
- Austria
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
End Stage Liver DIsease, Obesity
Use of Direct Peritoneal Resuscitation in High-risk Liver Transplant Recipients
This study is being conducted to assess the safety of Direct Peritoneal Resuscitation (DPR) in high-risk liver transplant patients.
- Conditions
- End Stage Liver DIsease, Obesity, Acute Kidney Injury
- Trial name
- NCT05195125
- Testing
- Direct Peritoneal Resuscitation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Colorado, Denver