Clinical trials: Obese Subjects
Obese, Hypertension
Effect of Green Tea in Obese Pre-hypertensive Women
The purpose of this study is to evaluate the effects of green tea on body weight, waist circumference, metabolic profile, inflammation, blood pressure and endothelial function in obese pre-hypertensive women.
- Trial name
- NCT01861171
- Testing
- Green Tea
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Overweight, Obese
Evaluating the Effects Two Diets Combined With Exercise in Persons With Abdominal Obesity (The SHAPE5 Study)
Abdominal obesity, which is affected by a lack of physical activity and excess weight, put people at an increased risk of cardiovascular disease.
- Conditions
- Overweight, Obese, Sedentary, Abdominal Obesity
- Trial name
- SHAPE5 (NCT00990457)
- Testing
- Weight Loss Diets Plus Exercise
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Prediabetic State, Overweight
Glucose Metabolism Effects of Vitamin D Supplementation in Prediabetes
Vitamin D deficiency is widespread throughout the world, and the deficiency has been associated with several chronic diseases, such as cardiovascular diseases and diabetes.
- Conditions
- Prediabetic State, Overweight, Obese
- Trial name
- VitDmet (NCT01479933)
- Testing
- Vitamin D3, Vitamin D 80
- Where
- Finland
- Volunteers
- 73 people
- Sponsor
- University of Eastern Finland
Morbidly Obese, Intubationtime
Intubation of Morbidly Obese Patients. A Clinical Trial, Comparing Glide Scope ® With Fastrach TM
The purpose of this study is to compare the GlideScope ® and the Fastrach TM for intubation of morbidly obese. Mainly we will try to clarify which of the instruments that produce the shortest intubationtime and lowest number of…
- Conditions
- Morbidly Obese, Intubationtime, Intubationattempts
- Trial name
- NCT01237080
- Testing
- GlideScope, Fastrach
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Overweight, Obese
Effects of Journaling on Weight Loss
This is a randomized controlled trial with enhanced usual care treatment control. The aim is to determine the effects of journaling and use of resource website on weight loss. There will be two groups of 55 participants each.
- Trial name
- NCT01660685
- Testing
- Tracking, Journaling, Website
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Milton S. Hershey Medical Center
Type 2 Diabetes, Diabetes Mellitus, Type 2
Comparative Bioavailability - Gender Effect - Single and Multiple Ascending Dose Safety and Pharmacokinetic Study of GFT505
The Sponsor, Genfit, has developed a new formulation of GFT505 (60 mg). The objective is to compare the relative bioavailability between the new GFT505 formulation (capsule dosed at 60 mg GFT505) and the old GFT505 formulation…
- Conditions
- Type 2 Diabetes, Diabetes Mellitus, Type 2, Metabolic Diseases, Cardiovascular Diseases
- Trial name
- NCT01474161
- Testing
- GFT505 120mg - old formulation, GFT505 120mg - new formulation, GFT505 180mg - new formulation
- Where
- France
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Genfit
Obese
Metabolism Associated With Abdominal Fat Mass Distribution
Objectives: The primary objective of this clinical trial is to characterize metabolic signatures associated with abdominal fat distribution in 40 women with different BMI 29-40 and different abdominal distribution of fat…
- Trial name
- NCT01726647
- Where
- 2 sites in Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Overweight, Obese
Efficacy of a Web-based Weight Loss Program
Since overweight and obesity, a risk factor for various diseases, is a prevalent problem in the modern society, it is important to search for new strategies to counteract this.
- Trial name
- NCT01634204
- Testing
- KiloCoach, Control
- Where
- 3 sites in Austria, Germany
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Obese
Prone Versus Left-sided Colonoscopy in Obese Patients
For obese patients, a randomized trial aimed at determining whether colonoscopy performance and patient comfort is improved if a patient is in the prone position (lay on their abdomen) versus the traditional left-sided position.
- Trial name
- NCT01616602
- Testing
- Prone Position, Standard Position
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dallas VA Medical Center
Metabolic Syndrome, Subclinical Organ Damage
Subclinical Organ Damage in Overweight and Obese Patients: Does Presence of Metabolic Syndrome Matter?
Microalbuminuria and homocysteine levels are shown to be markers for endothelial dysfunction and subclinical organ damage and predictors of cardiovascular risk in several epidemiologic and randomized clinical trials.
- Conditions
- Metabolic Syndrome, Subclinical Organ Damage, Overweight, Obese
- Trial name
- NCT01586754
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Goztepe Training and Research Hospital
Obese, Infertility
Comparison Between Two Fertility Protocols in Obese Polycystic Ovary Syndrome Patients
The purpose of this study is to compare two fertility protocols in obese women with Polycystic Ovarian Syndrome who are candidates for In Vitro Fertilization (IVF).
- Conditions
- Obese, Infertility, Polycystic Ovary Syndrome
- Trial name
- NCT01473459
- Testing
- IVM (In Vitro Maturation) Treatment, IVF (In Vitro Fertilization) Antagonist Protocol
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Morbidly Obese
Use of Breath Stacking Technique on Regional Ventilation in Box Chest in Women With Morbid Obesity
Objectives: To evaluate the effects of the technique of Breath Stacking (BS) in the distribution of ventilation in the chest in women with morbid obesity.
- Trial name
- NCT01551277
- Testing
- BREATH STACKING
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal de Pernambuco
Adult Women, Overweight
Effects of Flaxseed Flour in Appetite Sensations, Lipid Profile and Pressure Levels Among Overweighed and Obese Women
Inclusion of foods rich in fiber, such as flaxseed, is a nutritional strategy for treating obesity. The hypothesis of this study is to compare the effects of three types of flaxseed flour - whole brown flaxseed flour, brown…
- Conditions
- Adult Women, Overweight, Obese
- Trial name
- NCT01549626
- Testing
- Defatted flaxseed flour, Golden flaxseed flour, Whole brown flaxseed flour
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Obese
Safety and Preliminary Effectiveness of the BaroSense Articulating Circular Endoscopic (ACE) Stapler for Plication of Dilated Post-surgical Gastric Anatomy
The BaroSense Articulating Circular Endoscopic (ACE) Stapler is an investigational instrument indicated for endoluminal trans-oral tissue approximation and ligation in the gastrointestinal tract.
- Trial name
- NCT01388673
- Testing
- BaroSense ACE Stapler for plication of dilated post-surgical gastric anatomy
- Sponsor
- BaroSense Inc.
Overweight, Obese
AZD7687 Multiple Ascending Dose Study
The aim of the study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD7687 following multiple ascending dose administrations in in overweight to obese but otherwise healthy male subjects
- Trial name
- NCT01119352
- Testing
- AZD7687
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Obese Pregnant Women
Effect of Psycho-education on Gestational Weight Gain and Anxiety/Depression in Obese Pregnant Women
Prepregnancy obesity, defined as a body mass index (BMI) of 30kg/m² or more, shows a strong association with pregnancy and birth complications for both the mother and her child.
- Trial name
- NCT01329835
- Testing
- Lifestyle counseling, brochure
- Where
- 3 sites in Belgium
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Limburg Catholic University College
Surgical Site Infection in Obese Women Undergoing C-section
Use of 48 Hour Course of Antibiotics to Prevent Surgical Site Infection in Obese Patients Undergoing Cesarean Delivery
The purpose of this study is to evaluate if preoperative antibiotics, followed by 48 hour course of broad spectrum antibiotics prevents wound infection complications in patients that are obese who undergo cesarean section.
- Trial name
- SSI (NCT01194115)
- Testing
- cephalexin & metronidazole
- Where
- United States
- Volunteers
- 475 people
- Sponsor
- University of Cincinnati
Recovery Time From Isoflurane Anesthesia in Obese Patients
Acceleration of Recovery From General Anesthesia - Efficacy of Isocapnic Hyperpnoea in Obese Patients Undergoing Isoflurane Anesthesia
Faster recovery from anesthesia is important for obese patients because they are at high risk of respiratory complications following tracheal extubation.
- Trial name
- NCT00752492
- Testing
- Isocapnic Hyperpnoea
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University Health Network, Toronto
Overweight, Obese
Cholinergic Status and the Metabolic Syndrome
The investigators aims in the current study are to examine whether the cholinergic status should be considered as another risk factor for the metabolic syndrome and it's co-morbidities and to test the effect of a hypocaloric high…
- Trial name
- Choliner stat (NCT01332708)
- Testing
- high complex carbohydrates diet given in a diet group
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obese, Atracurium
Peri -and Postoperative Drug Therapy Schedules for Morbidly Obese Patients
Rationale: Obesity is an increasing health risk worldwide, with the USA recording prevalence in adults of around 20%. The mean body weight of obese patients is also increasing.
- Conditions
- Obese, Atracurium, Cefazolin, Morphine
- Trial name
- POP-II (NCT01097148)
- Testing
- Atracurium, TBW
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- St. Antonius Hospital