Clinical trials: Obesity, Childhood
Childhood Obesity
Respiratory Effects of Obesity in Children
In obese children, excess fat on the thorax exerts an unfavorable burden on the respiratory system, particularly during exercise; however, it is unclear if this burden reduces exercise tolerance, provokes dyspnea on exertion, or…
- Trial name
- NCT03376880
- Testing
- 1 year follow-up testing
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hypothalamic Obesity, Multiple Pituitary Hormone Deficiency Genetic Form
A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)
This is a sub-study of Study RM-493-040 (NCT05774756). The goal of this sub-study is to learn how well Setmelanotide works to improve weight reduction, hunger, and quality of life in patients 4 years of age and older with…
- Conditions
- Hypothalamic Obesity, Multiple Pituitary Hormone Deficiency Genetic Form, Septo-Optic Dysplasia, Optic Nerve Hypoplasia
- Trial name
- NCT06760546
- Testing
- Setmelanotide
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 39 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Pediatric Obesity
Improving Pediatric Obesity Practice Using Prompts
This study compares the effectiveness of electronic health record (EHR)-based tools to support the management of pediatric obesity in primary care.
- Trial name
- iPOP-UP (NCT03648242)
- Testing
- Interruptive Clinical Decision Support
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Yale University
Obesity, Childhood
Storytelling To Prevent Obesity and Encourage Responsive Feeding Practices in Young Children
The goal of this qualitative trial study is to assess the usefulness and acceptability of the intervention in diverse clinical and community settings.
- Trial name
- STORY (NCT05994924)
- Testing
- Educational Handout, Video Series, Group Discussion Sessions
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Childhood Obesity
Impact of Exergaming on Adolescent Youth
The purpose of this study is to gather information on how much exercising with video games (ExerGaming) can increase the physical activity among overweight and youth.
- Trial name
- NCT01374386
- Testing
- Exergaming
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
PCOS, Adolescent Obesity
Treating PCOS With Semaglutide vs Active Lifestyle Intervention
Girls with obesity and polycystic ovarian syndrome will receive either glucagon like peptide-1 receptor agonist therapy or a dietary intervention for 12 weeks to decrease the metabolic syndrome, in particular to lower hepatic fat…
- Conditions
- PCOS, Adolescent Obesity, NAFLD
- Trial name
- TEAL (NCT03919929)
- Testing
- Semaglutide 3mg and 7mg [Rybelsus], Weight loss diet
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
NAFLD, Low-free Sugar Dietary
Dietary Intervention for Low Free Sugars in Children With Non-alcoholic Fatty Liver Disease
A 48-week dietary intervention program was conducted in children aged 5-14 years with a diagnosis of NAFLD, who were randomized into a low free sugar diet group and a regular diet group.
- Conditions
- NAFLD, Low-free Sugar Dietary, Child Obesity
- Trial name
- NCT06579729
- Testing
- Dietary intervention for low free sugars
- Where
- China
- Volunteers
- 146 people
- Sponsor
- China Medical University, China
Breastfeeding, Bottle Feeding
Using Digital Health Technologies to Prevent Rapid Infant Weight Gain.
A digital intervention to provide supplemental infant feeding support to mothers enrolled in WIC. The trial begins prenatally and continues through 3-months postpartum and tests the feasibility and acceptability of a text…
- Conditions
- Breastfeeding, Bottle Feeding, Child Obesity
- Trial name
- NCT05265845
- Testing
- Intervention, Text4Baby
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Childhood Obesity
Healthy Kids Pilot
Up to 30 parent/child dyads will be recruited to participate in an m-Health intervention (delivered over smartphone, iPad/Tablet, or desktop/laptop) to promote healthy behaviors and healthy weight among children and their parents.
- Trial name
- NCT03297554
- Testing
- m-Health Intervention
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity, Childhood
Black Adolescent & Entertainment Study
The study is being conducted to obtain adolescent girls' thoughts and opinions on relationship and communication styles are shown on television.
- Trial name
- NCT03537755
- Testing
- Observation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Obesity, Childhood, Orthodontic Treatment
Evaluation of the Effects of Obesity on Orthodontic Tooth Movement
In this study, bone remodeling in the gingival crevicular fluid was evaluated biochemically during canine distalization in obese individuals and compared with normal weight individuals.
- Trial name
- NCT05988723
- Testing
- ELISA kits
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Gestatiaonl Diabetes Mellitus, Insulin Resistance
Impact of Gestational Diabetes on Childhood Obesity
In this study, we aimed to investigate the relationship between obesity, glucose intolerance (insulin resistance), dyslipidemia and diabetes in children aged 5-12 born to mothers with Gestational Diabetes Mellitus (GDM) in…
- Conditions
- Gestatiaonl Diabetes Mellitus, Insulin Resistance, Dyslipaemia, Obesity &Amp; Overweight
- Trial name
- NCT07069296
- Testing
- blood samples were collected from participants, blood samples
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Obesity
Effect of Recombinant Human Growth Hormone (rhGH) on Abdominal Fat and Cardiovascular Risk in Obese Girls
Teenagers and adults who are overweight or obese have an increase in fat in the abdomen, which increases their risk for diabetes and heart disease.
- Trial name
- NCT01169103
- Testing
- recombinant human growth hormone (rhGH)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Massachusetts General Hospital
Food Deprivation, Obesity, Childhood
Improving Participation in Universal School Meals (USM)
The purpose of this study is to assess the impact of an implementation strategy on participation in Universal School Meals (USM).
- Trial name
- NCT06579079
- Testing
- Implementation Mapping, Waitlist Comparison - Implementation Mapping
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Temple University
Pediatric Obesity
Juntos Santiago: Gamification Strategy to Reduce Childhood Obesity in Schools in Santiago de Chile
School-based interventions have shown mixed results. Most studies have lacked enough statistical power and have been carried out in North America and Europe.
- Trial name
- NCT03459742
- Testing
- Gamification strategy
- Where
- 2 sites in Chile
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Municipality of Santiago
Stress, Eating Behavior
Stress Reactivity Study in Adolescents
The goal of this study was to examine the glucocorticoid and behavioral responses to a psychological stressor in obese African-American and non-Latino white adolescents.
- Trial name
- SRAS (NCT03997149)
- Testing
- Acute Laboratory Stressor, Low affect video
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obesity, Adolescent, PreDiabetes
Unsweetened Sparkling Water and Changes in Sweetness Perception in Adolescents
The study design is a prospective observational study in adolescents who are at risk for developing Type 2 Diabetes (T2D), to evaluate the effectiveness of sparkling water to reduce dietary intake of added sugars and thereby…
- Trial name
- NCT05966870
- Testing
- Unsweetened flavored sparkling water
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Indiana University
Pediatric Obesity
Pediatric Quality of Life Among Population With Body Mass Index (BMI) Greater Than or Equal to 85%
We are currently experiencing an epidemic of obesity in the Pediatric Population. This epidemic affects many areas including quality of life. We have been conducting a nutrition and exercise program since 2003.
- Trial name
- NCT00714870
- Testing
- Behavioral nutrition and exercise program
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Obesity, Childhood
A Primary Care Based Intervention to Prevent Childhood Obesity Among Low-income Latino Children
The goal of this study is to evaluate the impact of a primary care based intervention to promote optimal feeding, screen time and sleep practices among low-income Latino infants and toddlers.
- Trial name
- NCT06398509
- Testing
- Control, Futuros Fuertes 2.0
- Where
- 2 sites in United States
- Volunteers
- 576 people
- Sponsor
- University of California, San Francisco
Childhood Obesity, Nutrition Poor
Choose Health: Food, Fun, and Fitness Curriculum Promotes Positive Behaviors in 3rd-5th Graders Compared to Control
The Choose Health: Food, Fun, and Fitness (CHFFF) curriculum was evaluated in 3rd-5th graders, hypothesizing that change pre- to post- CHFFF education would be greater than in the same child during a delayed intervention control…
- Trial name
- NCT03524911
- Testing
- CHFFF nutrition education
- Volunteers
- 561 people, healthy volunteers welcome
- Sponsor
- Cornell University
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