Clinical trials: Obesity, Metabolically Benign
Obesity, Metabolically Benign
Effects of MET-3 and MET-5 on Gut Microbiome and Metabolic Function in Men and Women With Hypertriglyceridemia
The purpose of this pilot study is to determine the effects of two human microbiome formulations (MET-3 and MET-5) on fasting serum TG concentration.
- Trial name
- NCT04507971
- Testing
- MET-3
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- NuBiyota
Obesity
Metabolically Healthy Obesity: Correlations Between BMI and Metabolic Syndrome Biomarkers
The study team's research fills the gap in the obesity literature where BMI with a cut point of 35 is frequently used to show the association between BMI and metabolic syndrome biomarkers.
- Trial name
- NCT03195712
- Where
- United States
- Volunteers
- 691 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Healthy, Obesity, Metabolically
A First in Human (FIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DR10624
DR10624 is an Fc fusion protein tri-agonist with balanced glucagon-like peptide-1 receptor (GLP-1R)/glucagon receptor (GCGR)/ fibroblast growth factor 21 receptor (FGF21R) agonizing activities.
- Trial name
- NCT05378893
- Testing
- DR10624 for injection
- Where
- New Zealand
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Zhejiang Doer Biologics Co., Ltd.
Healthy Obesity, Metabolically, Appetite Regulation
Colonic Propionate, Appetite, and Weight Loss
The current protocol aims to investigate the impact of the propionate ester in conjugation with restricted diet on appetite and weight loss.
- Trial name
- ProAp (NCT03322514)
- Testing
- Inulin-Propionate Esters, Inulin
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity, Weight Loss
Effects of Physical Activity on Weight Loss and Weight Maintenance in Obese Adults - Three Year Follow-up Study
Objective To study if exercise added to weight loss treatment at the beginning of the weight loss intervention or at 6 months could sustain the weight loss achieved or give extra boost for weight reduction.
- Conditions
- Obesity, Weight Loss, Physical Activity, Healthy Obesity, Metabolically
- Trial name
- LILA (NCT03861754)
- Testing
- Lifestyle modification
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- University of Oulu
Metabolic Syndrome, Obesity, Metabolically Benign
Oxidative Stress, Inflammation, and Lipoprotein in Metabolic Syndrome
Obesity is associated with general low grade inflammation and, consequently, of oxidative stress that affects properties and functionality of lipoproteins. Metabolic syndrome exacerbate low grade inflammation.
- Trial name
- NCT03553381
- Testing
- hypocaloric balanced diet
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- roberta cazzola
Metabolic Syndrome, Obesity & Overweight
Breath Mass Spectrometry in Metabolic Syndrome and Metabolically Healthy Obesity
This study aims to develop a non-invasive diagnostic method for metabolic syndrome (MetS) and metabolically healthy obesity (MHO) through analysis of exhaled air.
- Conditions
- Metabolic Syndrome, Obesity & Overweight, Metabolically Healthy Obesity
- Trial name
- NCT07330297
- Testing
- Breath Sampling and Analysis by PTR-MS
- Where
- Russia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Obesity, Metabolically Benign
Effect of Diet and Physical Activity on Adipokines
The prevalence of metabolic syndrome (MetS) in young population continues to rise. Obesity is a chronic inflammatory disorder in which leptin, adiponectin and C reactive protein (CRP) play an important role.
- Trial name
- NCT03435978
- Testing
- MetS+, MetS-
- Volunteers
- 66 people
- Sponsor
- Louis Turcanu Emergency Hospital for Children
Metabolic Syndrome, Healthy Participants
Impact of Supplemental Fiber on Gut and Vascular Health Related in Obesity Phenotypes
Based on prior research, the investigators are interested in whether an intervention targeting gut health (supplemental fiber for 9 weeks total) will improve vascular health in individuals with obesity.
- Conditions
- Metabolic Syndrome, Healthy Participants, Metabolically Healthy Obesity, Metabolically Abnormal Obesity
- Trial name
- NCT07095426
- Testing
- inulin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ball State University
Metabolically Healthy Obesity
Brown Fat Tissue Related Hormone Levels in Metabolically Healthy and Unhealthy Obese Individuals
There are two types of adipose tissue in humans, white and brown adipose tissue. While the main task of white adipose tissue is energy storage, the main task of brown adipose tissue is energy expenditure.
- Trial name
- NCT05232695
- Testing
- metabolically healthy obese
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Metabolically Healthy Obesity
Gut, Immune, and Vascular Health in Metabolically Healthy Obesity
The investigators seek to better understand how a single high-fat meal impacts gut, immune, and vascular outcomes in individuals with "metabolically healthy obesity" (obesity and largely normal cardiometabolic profile) and…
- Trial name
- NCT07559227
- Testing
- Inulin Supplementation, High-fat meal
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ball State University