Clinical trials: Obesity, Overweight
Obesity
Investigation of the Effects of Bariatric Surgery on Taste Reward in Humans
The investigators hypothesize that some of these changes in the reduced appetite after surgery may be due to alterations in taste.
- Trial name
- NCT01531738
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity
A Study of a Novel Precision Medicine Approach For Obesity
This study is being done to assess the efficacy of a saliva- based biomarker to predict response to semaglutide for the treatment of obesity.
- Trial name
- NCT06814938
- Testing
- Semaglutide
- Where
- 2 sites in United States
- Volunteers
- 135 people
- Sponsor
- Mayo Clinic
Overweight, Obesity
Consumption of More Ideal Food Options (COMIDA: Consumo de Opciones Más Ideales De Alimentos)
The Mexican Consulate runs a Ventanilla de Salud (VDS) (Health Window) program in fifty locations nationwide. The VDS provides an opportunity to provide health services to members of the Mexican community.
- Trial name
- COMIDA (NCT03851458)
- Testing
- Initial in-person individual diet and exercise counseling (N vs. Y), Thrice weekly diet and exercise text messages (N vs. Y), Weekly telephone support (N vs. Y)
- Where
- United States
- Volunteers
- 1,785 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Obesity, Type 2 Diabetes
MagDI Canada Study
The objective of the MagDI Canada study is to evaluate the performance and safety of the MagDI System in eligible participants who are indicated for a duodeno-ileal (small bowel) side-to-side anastomosis procedure for partial…
- Trial name
- NCT06467955
- Testing
- Magnet System, DI Biofragmentable
- Where
- 3 sites in Canada
- Volunteers
- 60 people
- Sponsor
- GT Metabolic Solutions, Inc.
Obesity & Overweight
A Pharmacokinetic Study of VCT220 With Moderate Renal Impairment Patients
This Phase 1 study is designed to evaluate the pharmacokinetics and safety of a single oral dose of VCT220 (other name: CX11) in subjects with moderate renal impairment compared with age-, sex-, and body mass index (BMI)-matched…
- Trial name
- NCT07347808
- Testing
- VCT220
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Vincentage Pharma Co., Ltd
Overweight, Obesity
SELECT-LIFE: A Research Study Looking at Long-term Effects of Semaglutide in People Who Took Part in the SELECT Cardiovascular Outcomes Trial
Participants are being asked to participate in SELECT-LIFE study because participants take part in the SELECT trial. SELECT-LIFE study is a survey-based study that will start when the SELECT trial ends.
- Trial name
- SELECT-LIFE (NCT04972721)
- Testing
- No treatment given
- Where
- 38 sites in United States, Algeria and 22 more
- Volunteers
- 3,439 people
- Sponsor
- Novo Nordisk A/S
Aging, Diabetes Mellitus, Type 2
Effect of GLP1 Receptor Agonists on Physical Function, Body Composition, and Markers of Aging in Older Adults
Semaglutide is a medication approved by the US Food and Drug Administration (FDA) as an antihyperglycemic (a drug that reduces glucoses in those with diabetes) and for weight management.
- Conditions
- Aging, Diabetes Mellitus, Type 2, PreDiabetes, Overweight and Obesity
- Trial name
- NCT05786521
- Testing
- Semaglutide Injectable Product, Lifestyle Counseling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Obesity
The Role of Values, Acceptance, and Mindfulness Strategies in Long Term Weight Management
Obesity is a prevalent, destructive, and costly chronic disease. In 2008, 37% of Canadian adults were measured as overweight, and 25% as obese.
- Trial name
- NCT02749552
- Testing
- Acceptance and Commitment Therapy
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Childhood Obesity
Nutrition and Physical Activity Counselling
Background: Childhood obesity imposes a great burden on the healthcare system. Given the increased frequency of dental compared to medical visits during childhood, dentists may be in an ideal position to recognize patients at…
- Trial name
- NCT02637752
- Testing
- Lifestyle counseling or nutrition/physical counselling
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity & Overweight, Respiratory Depression
Oxytocin for Respiratory Compromise and Hypoventilation Induced by Drugs
Drug overdose is a national crisis. The primary cause of death associated with opioids is opioid-induced respiratory depression.
- Conditions
- Obesity & Overweight, Respiratory Depression, Intranasal Drug Administration, Oxytocin
- Trial name
- ORCHID (NCT07902752)
- Testing
- Intranasal Oxytocin 40 i.u.
- Volunteers
- 100 people
- Sponsor
- George Washington University
Obesity and Obesity-related Medical Conditions
Precision Nutrition Technologies for Obesity Management
The implementation of this project will develop and apply precision health dietary solutions tailored for weight management in China's obese population, establishing a precision nutrition intervention model.
- Trial name
- NCT07101133
- Testing
- Control group: Energy-limited balanced diet group
- Volunteers
- 600 people
- Sponsor
- Yuan He
Obesity, Insulin Resistance
Effect of Probiotic Co-administration With Omega-3 Fatty Acids on Obesity Parameters and Insulin Resistance
Probiotics are defined as live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. Omega-3 fatty acids belong to the family of polyunsaturated fatty acids.
- Conditions
- Obesity, Insulin Resistance, Insulin Sensitivity, Type2 Diabetes
- Trial name
- ENDO-5 (NCT04201938)
- Testing
- Symbiter-Omega
- Where
- Ukraine
- Volunteers
- 56 people
- Sponsor
- Bogomolets National Medical University
Diabetic Foot Ulcer
Effect of Adiposity and Associated Local Microbial Factors on Healing and Progression of Diabetic Foot Ulcers
Diabetic foot ulcers (DFUs) and their associated complications like amputations are increasingly becoming a problem in low and middle income (LMI) countries.
- Trial name
- NCT03960255
- Testing
- Normal standard care
- Where
- 4 sites in Tanzania
- Volunteers
- 300 people
- Sponsor
- Muhimbili University of Health and Allied Sciences
Gastroesophageal Reflux Disease, Obesity
Waist Circumference Versus Body Mass Index to Predict Severity of Gastroesophageal Reflux Disease
Gastroesophageal reflux disease (GERD) is a common and important disorder. Previous studies have demonstrated the association of obesity with GERD, and now obesity is regarded as a risk factor for GERD.
- Trial name
- NCT00698178
- Testing
- Anthropometric measurements
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- Lotung Poh-Ai Hospital
NIDDM, Obesity
Effect of Metformin, a Drug Used to Treat Diabetes, vs Placebo
Metformin is a drug used to treat patients with diabetes. The aim of this study is to examine the effect of Metformin along with a low-calorie diet on obese and/or overweight adults with an increased waist measurement.
- Trial name
- NCT05949008
- Testing
- Metformin Extended Release (ER) Oral Tablet
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Sedentary Behavior
Reducing Sedentary Time in Obese Adults
Greater time spent in sedentary behaviors, independent of physical activity level, can increase risk of morbidity and mortality.
- Trial name
- NCT01688804
- Testing
- Behavioral intervention to reduce sedentary time delivered via mobile smartphone
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Overweight/Obesity
The Evaluation of Bioequivalence Between a Single-dose Pen and a Multi-dose Pen of HRS9531 Injection Solution
The study is being conducted to evaluate the bioequivalence between a single-dose pen and a multi-dose pen of HRS9531 injection solution.
- Trial name
- NCT06792955
- Testing
- HRS9531 injection
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Inflammation, Obesity
Effects of a PUFA-rich Diet on Acute Metabolic and Inflammatory High-Fat Meal Responses
This study evaluates whether a diet rich in poly-unsaturated fats can compensate for the negative effects of high saturated fat meals on metabolic, inflammatory, and coagulation responses.
- Trial name
- NCT02246933
- Testing
- PUFA Diet, Control Diet
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Kidney Diseases, Obesity
Epidemiologic Data of Patients in a Teaching Hospital
This small cross-sectional epidemiological study is designed to evaluate the prevalence of the following parameters in hospitalized patients in a tertiary teaching hospital (medical department only): kidney insufficiency obesity…
- Trial name
- NCT00114335
- Where
- Switzerland
- Volunteers
- 352 people
- Sponsor
- Luzerner Kantonsspital
Sleep Disturbance, Sleep Wake Disorders
Improving Sleep Health in Adults With Overweight or Obesity
This study will examine the feasibility and acceptability of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) in adults with poor sleep and excess weight.
- Conditions
- Sleep Disturbance, Sleep Wake Disorders, Sleep Disorder
- Trial name
- NCT04990206
- Testing
- TranS-C
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Pittsburgh
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