Clinical trials: Obesity, Overweight
Obesity, Adolescent
PathMate2: The Impact of Health Information System Services on the Effects of Therapy in Overweight Teenagers
Randomised controlled trial in overweight adolescents using a health App.
- Trial name
- PM2 (NCT03270423)
- Testing
- PathMate2, PathMateS
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Ostschweizer Kinderspital
Erectile Dysfunction
Effect of Lifestyle Changes on Erectile Dysfunction in Obese Men: a Randomized Controlled Trial
Healthy lifestyle factors are associated with maintenance of erectile function in men. To determine the effect of weight loss and increased physical activity on erectile and endothelial functions in obese men.
- Trial name
- NCT00636688
- Testing
- Lifestyle - detailed advice, Control - general information
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Obesity
Impact of Ketogenic Diets in Preventing Relapse in Obesity Management
Low-carb ketogenic diets have become extremely popular because of large weight loss in the short-term. Yet their potential benefits in preventing long-term weight regain have not been assessed in large scale studies.
- Trial name
- Ketomaintain (NCT04382183)
- Testing
- Ketogenic weight loss maintenance diet, Isocaloric balanced weight loss maintenance diet
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Surgical Wound Dehiscence, Wound Infection
Prevention of Wound Complications After Cesarean Delivery in Obese Women Utilizing Negative Pressure Wound Therapy
Wound complications after Cesarean section (C-section) are common in obese women. Approximately 25% of obese women having a C-section will have a wound complication.
- Trial name
- NCT00654641
- Testing
- Negative pressure wound closure, Standard wound closure
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- West Virginia University
Obesity, Cardiovascular Disease
Change Clubs for African American Women
African American women have among the highest rates of overweight and obesity and few meet dietary or physical activity guidelines.
- Trial name
- NCT02173366
- Testing
- Change Club Intervention
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Tufts University
Obesity
Intermittent Fasting Versus Daily Caloric Restriction for Weight Loss
The primary aim of this study is to is to determine if intermittent fasting (IMF) is an effective dietary strategy for treatment of obesity.
- Trial name
- NCT03411356
- Testing
- Daily Caloric Restriction (DCR), Intermittent Fasting (IMF)
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Diabetes type2, Obesity
Epigenetic and Microbiota Modifications
In order to investigate how gut microbiota interventions are able to change gut microbiota population and impact insulin resistance, 30 type2 diabetes volunteers with obesity will be randomized to one of the three treatment…
- Trial name
- EPI-MICROBIO (NCT05076656)
- Testing
- Lactobacillus fermentum D3, Fecal microbiota transplant (FMT)
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Obesity
The Tailgate Study: A Pilot Study Measuring the Impact of Acute Alcohol Intake on Intrahepatic Lipid
College drinking associated with sporting events is characterized by excess alcohol, along with food intake, over the duration of hours has the potential to cause a build up of fat in the liver.
- Trial name
- NCT02141880
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obesity, Weight Control
European Study to Evaluate Preliminary Safety and Efficacy of Multiple Obalon Gastric Balloons for 12 Weeks as an Aid for Weight Loss
The objective of this study is to evaluate the initial safety and preliminary effectiveness of the Obalon intragastric balloon system in European subjects with a BMI in the range of 27 - 35 kg/m^2
- Trial name
- NCT01718886
- Testing
- Obalon Gastric Balloon
- Where
- 2 sites in Belgium, France
- Volunteers
- 17 people
- Sponsor
- Obalon Therapeutics, Inc.
Obesity, Insulin Resistance
Vitamin D Supplementation to Obese Chinese Males
Hypothesis: Oral Supplementation of Vitamin D can Reduce Hypersecretion of Parathyroid Hormone and Insulin Resistance in Obese Chinese Males.
- Trial name
- NCT01781169
- Testing
- Oral supplementation of vitamin D
- Where
- China
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Chronic Disease Control
Obesity
HERO Study: Helping Evaluate Reduction in Obesity
A prospective, international, multi-center study of clinical outcomes and estimated healthcare resource expenditures associated with the treatment of obesity using the LAP-BAND AP® Adjustable Gastric Banding System.
- Trial name
- NCT00953173
- Testing
- LAP-BAND AP® Adjustable Gastric Banding System
- Where
- 6 sites in United States, Australia and 4 more
- Volunteers
- 671 people
- Sponsor
- Apollo Endosurgery, Inc.
Obesity
Central Nervous Processing of Visual Food Stimuli in Severely Obese Subjects
Recent evidence has pointed to distinct alterations of brain functions in obese subjects some of which may even be causative for their obesity.
- Trial name
- NCT01493583
- Where
- Switzerland
- Volunteers
- 38 people
- Sponsor
- Cantonal Hospital of St. Gallen
Obesity
Circulating IL-6, Clusterin and Irisin in Obese Subjects
evaluate the circulating levels of IL-6, clusterin and irisin in obese subjects of both sexes who had different classes of obesity and their sexual dimorphism also identify the association of IL-6, clusterin and irisin with…
- Trial name
- NCT04133896
- Testing
- IL-6, Clusterin, Irisin Level
- Where
- Egypt
- Volunteers
- 176 people
- Sponsor
- Rehab Werida
Prader-Willi Syndrome
Study to Evaluate Efficacy, Safety, and Tolerability of RGH-706 in Prader-Willi Syndrome
RGH-706 is a novel, potent, and orally active MCHR1 antagonist drug candidate discovered and being developed by Gedeon Richter Plc. for weight management.
- Trial name
- NCT05322096
- Testing
- RGH-706
- Where
- 23 sites in United States, Czechia and 3 more
- Volunteers
- 39 people
- Sponsor
- Gedeon Richter Plc.
Obesity
Collaborative Multi-level Obesity Intervention Engaging Communities Trial
The goal of this clinical trial is to test the effectiveness of an evidence-based multi-level intervention for weight loss and the feasibility, fidelity, and sustainability of implementing the intervention in people living with…
- Trial name
- CONNECT (NCT06835686)
- Testing
- Health Literacy and Culturally Tailored Materials, Community-Engaged Health Coaching and Navigation, Self-Monitoring and Remote Patient Monitoring of weight and physical activity
- Where
- 18 sites in United States
- Volunteers
- 522 people
- Sponsor
- Tulane University
Abdominal Obesity, Insulin Resistance
The Effect of Nordic Recommended Diet on the Features of Metabolic Syndrome - Multicentre Study
SYSDIET (Systems biology in controlled dietary interventions and cohort studies) is one of the three centres in the NCoE Food, Nutrition and Health, 2007-2011.
- Conditions
- Abdominal Obesity, Insulin Resistance, Impaired Glucose Tolerance, Type 2 Diabetes
- Trial name
- SYSDIET (NCT00992641)
- Testing
- Experimental diet, Control diet
- Where
- 8 sites in Denmark, Finland and 3 more
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Marjukka Kolehmainen
Pre Diabetes, Overweight and Obesity
A Digital Therapy for Diabetes Prevention Among Overweight Adults in Terengganu, Malaysia
The modern world revolves around technology; unsurprisingly companies are leveraging the expertise of the digital tech industry to aid in the prevention of chronic diseases.
- Trial name
- NCT03997656
- Testing
- MyDiPP (Malaysia Diabetes Prevention Program), usual care
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- Universiti Sultan Zainal Abidin
Feeding Behavior, Brain
Food Intake and the Adolescent Brain
The brain plays an integral role in how and what people eat. However, the brain's contribution to overeating is not well understood during sensitive developmental periods such as adolescence, when excessive weight gain and…
- Conditions
- Feeding Behavior, Brain, Adolescent
- Trial name
- ADOB (NCT04208256)
- Testing
- Energy Stimulus
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obese Type 2 Diabetic Patients
Modified Atkins Diet and Type 2 Diabetic Patients
This randomized control trial compared the influence of an Atkins diet to that of the ADA recommended diet on Type 2 diabetic obese patients during a one-year follow-up period
- Trial name
- NCT00552890
- Testing
- modified Atkins diet, ADA recommended diet
- Volunteers
- 52 people
- Sponsor
- Hadassah Medical Organization
Obese Patients
Soluble Advanced Glycation End Product (sRAGE) Levels
The aim of this study is to evaluate sRAGE levels in children with obesity and to determine the relationship between metabolic status and sRAGE levels in childhood obesity
- Trial name
- NCT06771986
- Testing
- Observation
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Kayseri City Hospital
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