Clinical trials: Obesity, Overweight
Type 2 Diabetes, Obesity and Overweight
Meal Frequency and Timing on Metabolic Health in Patients With Type 2 Diabetes
The goal of this clinical trial is to learn if changing when and how often people eat works to improve health in adults with Type 2 diabetes.
- Trial name
- NCT07674875
- Testing
- Control Arm - standard of care, Three Meal Group, Time-restricted eating
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Akdeniz University
Obesity, Overweight
A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
The main purpose of this study is to evaluate the safety and efficacy of tirzepatide in adolescents that have obesity or overweight with at least one weight-related comorbidity.
- Trial name
- NCT06075667
- Testing
- Tirzepatide
- Where
- 33 sites in United States, Canada and 4 more
- Volunteers
- 160 people
- Sponsor
- Eli Lilly and Company
Postpartum Weight Retention, Overweight and Obesity
Time-restricted Eating for Postpartum Weight Loss
This study is being done to assess the feasibility and acceptability of a time-restricted eating intervention among postpartum women with overweight/obesity.
- Trial name
- Time4Mom (NCT06491537)
- Testing
- Early Time-Restricted Eating (eTRE), Control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Obesity, Overweight
A Study to Evaluate the Drug Interactions of HRS-7535 With Acetaminophen, Digoxin, Rosuvastatin, and Omeprazole in Obese or Overweight Subjects
This study is an open-label, fixed-sequence, self-controlled Phase I clinical trial conducted among obese or overweight subjects, with a planned enrollment of 40 adult subjects.
- Trial name
- NCT07269756
- Testing
- HRS-7535 Tablets, Paracetamol Tablets, Digoxin Tablets
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
Obesity & Overweight
Ultra-processed Food Consumption and Health Pilot Study
The objective of this study is to explore the effects of two dietary conditions (UPF-diet and typical American diet) on a number of clinical and metabolic outcomes in order to derive sample size estimates for a larger trial and…
- Trial name
- ULTRA PIlot (NCT07318064)
- Testing
- Purple Diet, Ultra-processed diet
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Colon Neoplasms, Crohn Disease (CD)
Feasibility Study of the SEGER Device in Laparoscopic Gastrointestinal Surgery
This is a first-in-human feasibility study designed to evaluate the safety and performance of the SEGER device in patients undergoing elective laparoscopic gastrointestinal surgery requiring intracorporeal anastomosis.
- Conditions
- Colon Neoplasms, Crohn Disease (CD), Obesity & Overweight
- Trial name
- SEGER-FIH (NCT07508592)
- Testing
- SEGER Device
- Where
- El Salvador
- Volunteers
- 10 people
- Sponsor
- Seger Surgical Solutions
Obesity & Overweight, Bariatric Surgery
Time-Restricted Eating After Bariatric Surgery
This study aims to compare the effects of time-restricted eating (TRE, 16/8) in adults with obesity who have and have not undergone bariatric surgery (BS).
- Conditions
- Obesity & Overweight, Bariatric Surgery, Weight Regain, Weight Regain Post Bariatric Surgery
- Trial name
- NCT07672821
- Testing
- Time-Restricted Eating (16:8)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Overweight and Obesity, Adiposity
Healthy Mothers-Healthy Children Nutrition
Using a randomized two-group, repeated measures experimental design, the goal of the proposed study is to investigate the efficacy of a 12-week nutrition and exercise education, physical activity, coping skills training, and…
- Conditions
- Overweight and Obesity, Adiposity, Nutrient; Excess, Physical Activity
- Trial name
- HMHC (NCT03866902)
- Testing
- Nutrition and Physical Activity Intervention, English for Second Language Intervention
- Where
- United States
- Volunteers
- 578 people, healthy volunteers welcome
- Sponsor
- University of Miami
Overweight and/or Obesity
Piloting a Generative Artificial Intelligence Chatbot in a Mobile Weight Loss Program
The goal of this study is to learn if integrating a chatbot into an existing 12-week smartphone-delivered behavioral weight loss program is feasible and effective for weight loss among young adults.
- Trial name
- NCT07534254
- Testing
- AGILE Intervention, Chatbot
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Weight Loss, GLP - 1
Scalable Behavioral Program for Weight Loss Maintenance After GLP-1 and Anti-Obesity Medication Discontinuation
This study is a single-site, pilot randomized factorial trial designed to evaluate the feasibility, acceptability, participant perceptions and preliminary effects of a multi-component behavioral intervention to support weight…
- Conditions
- Weight Loss, GLP - 1, Weight Loss Maintenance, Obesity & Overweight
- Trial name
- NCT07535892
- Testing
- Weight Loss Maintenance Program (Foundational), Mom's Meals, YMCA Membership
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Alabama at Birmingham
Obesity, Overweight
A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or Obesity
This clinical study is testing two versions of the study medicine cagrilintide. The purpose of the study is to compare these two versions to understand their effects in participants with overweight or obesity.
- Trial name
- NCT07597018
- Testing
- Cagrilintide D
- Where
- Germany
- Volunteers
- 234 people
- Sponsor
- Novo Nordisk A/S
Hypertension (HTN), Obesity & Overweight
University of Georgia Mind Your Heart Pilot Study
The goal of this observational study is to learn if nutrition education can improve eating habits and health outcomes in adults. The main questions it aims to answer are: 1.
- Trial name
- NCT07670910
- Testing
- Mind Your Heart, DASH Diet Education
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Overweight and Obesity, Elevated Triglycerides
A Trial to Assess Full-fat or Low-fat Dairy Foods on Insulin Sensitivity, RBC FA's and Other Markers of Metabolic Health
The objectives of this trial are to assess the effects of adding 2 servings/d of either full-fat or low-fat fermented dairy products to the diet, as a replacement for non-dairy foods with macronutrient composition similar to the…
- Trial name
- NCT04999462
- Testing
- Full-fat fermented dairy, Low-fat fermented dairy, Non-dairy, non-fermented foods
- Where
- 4 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Liver Cancer, Adult, MASH - Metabolic Dysfunction-Associated Steatohepatitis
Time-restricted Eating and Healthy Eating in Patients With Metabolic Liver Disease or Cancer
This is a feasibility study that will collect data to assess the potential effect of nutritional intervention. This prospective single-site trial will enroll adult patients with liver diseases such as metabolic-dysfunction…
- Conditions
- Liver Cancer, Adult, MASH - Metabolic Dysfunction-Associated Steatohepatitis, Obesity and Overweight
- Trial name
- TRE+HE (NCT06824974)
- Testing
- Time-restricted eating plus healthy diet
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Obesity, Overweight
A Study of LY3841136 Compared With Placebo in Adult Participants With Obesity or Overweight
The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to investigate weight management efficacy and safety with LY3841136 compared with placebo in adult participants with obesity or…
- Trial name
- NCT06230523
- Testing
- Eloralintide
- Where
- 43 sites in United States
- Volunteers
- 263 people
- Sponsor
- Eli Lilly and Company
Overweight, Obesity
Study to Evaluate the Efficacy and Safety of KDS2010 in Overweight or Obese Patients
This is a randomized, double-blind, placebo-controlled, dose-finding, Phase 2a study designed to evaluate the safety and efficacy of KDS2010 in overweight or obese patients.
- Conditions
- Overweight, Obesity, Obese Patients
- Trial name
- NCT07009171
- Testing
- KDS2010
- Where
- 3 sites in South Korea
- Volunteers
- 75 people
- Sponsor
- NeuroBiogen Co., Ltd
Obesity & Overweight, Obesity (Disorder)
Optimizing Self-Monitoring Feedback Delivery for the Treatment of Overweight and Obesity
The purpose of this research study is to learn how to best provide weekly feedback on individual progress toward intervention goals during a weight loss program.
- Trial name
- NCT07227051
- Testing
- Feedback on Calorie Goal Attainment, Feedback on Dietary Quality, Feedback on Physical Activity Goal Attainment
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Obese Adults, Overweight , Obesity
ASSESSMENT OF THE NATURAL HISTORY AND PROGNOSTIC FACTORS OF THERAPEUTIC RESPONSE IN SUB-PHENOTYPES OF PATIENTS WITH OBESITY: THE BOLOBE STUDY
The study is observational and single-center and involves (i) the establishment of a retrospective and prospective data collection, and (ii) the development of prognostic and predictive models of response to obesity therapies…
- Trial name
- BOLOBE (NCT07666425)
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Type 2 Diabetes, Obesity & Overweight
Influence of the Use of Specific Nutritional Formulas on Time in Range in Patients With Type 2 Diabetes
Who can participate? Individuals may be eligible to join this study if they meet the following criteria: Are 18 years or older. Have Type 2 diabetes with an A1c level higher than 7%.
- Conditions
- Type 2 Diabetes, Obesity & Overweight, Time in Range
- Trial name
- NCT07666581
- Testing
- Glucerna, Caloric restriction
- Where
- Colombia
- Volunteers
- 198 people
- Sponsor
- Hospital Universitario San Ignacio
Respiratory Disease, Inflammation
Partners in Children's Health (CSN): A Randomized Trial of an Attachment Based Intervention
The goal of this randomized controlled trial is to evaluate the impacts of an attachment-based intervention (Attachment Biobehavioral Catch-Up (ABC) and Home Book-of-the-Week (HBOW) program on emerging health outcomes (i.e.…
- Conditions
- Respiratory Disease, Inflammation, Insufficient Sleep, Digestive Disease
- Trial name
- NCT06002685
- Testing
- Attachment and Biobehavioral Catch-Up, Home-Based Book-of-the-Week
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore