Clinical trials: Obesity, Overweight
Obesity & Overweight
A Study to Evaluate the Safety and Tolerability of Different Doses of CX11 Tablets
A multi-center, randomized, placebo-controlled, double-blinded (within cohorts), Sponsor-unblinded, Phase 1b study to explore the safety, pharmacokinetics, and pharmacodynamics of CX11 tablets in participants with obesity or…
- Trial name
- NCT07652047
- Testing
- CX11
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Corxel Pharmaceuticals
Overweight and Obesity
Validity and Reliability of Mixed Reality-Based Performance Tests in Overweight and Obese Adults
This study aims to evaluate the validity and reliability of mixed reality (MR)-based adaptations of functional mobility and performance tests developed using the Meta Quest 3 platform by comparing their outcomes with conventional…
- Trial name
- NCT07654439
- Testing
- Mixed Reality-Based Functional Mobility and Performance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 119 people
- Sponsor
- Selcuk University
Obesity & Overweight, Emotional Eating Behaviour
Mindfulness-Based Nutrition Group Therapy as an Adjunct to GLP-1 Treatment of Obesity
The goal of this clinical trial is to learn whether a mindfulness-based nutrition group program is feasible and acceptable for adults with obesity who are taking GLP-1 receptor agonist medication and receiving usual medical care…
- Conditions
- Obesity & Overweight, Emotional Eating Behaviour, Mindful Eating Intervention
- Trial name
- MBNGT (NCT07649759)
- Testing
- Mindfulness-based nutritional group therapy (MBNGT)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Bern University of Applied Sciences
Nutrition, Obesity and Overweight
The Causal Role of Ketone Bodies in Obesity-associated Disease Prevention - Combining Genetic Epidemiology With a Randomised Trial to Infer Causality
Excess weight increases the risk of several diseases including cardiovascular disease, type 2 diabetes, kidney disease and various cancers.
- Trial name
- KETO-GENETIC (NCT06668168)
- Testing
- Ketone Monoester (KE), Ketogenic diet
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Bath
GLP-1, Obesity &Amp; Overweight
Effect of a Dietary Supplement on Hormones Involved in Appetite Regulation in Overweight and Obese Adults
Obesity is a chronic condition linked to numerous health risks and affects more than one billion people worldwide. While pharmacological treatments such as incretin-based therapies are available, they may have side effects, are…
- Conditions
- GLP-1, Obesity &Amp; Overweight, Dietary Supplement
- Trial name
- NCT07240246
- Testing
- Intervention: Dietary Supplement with Plant Extracts
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- FFoQSI - Austrian Competence Centre for Feed and Food Quality, Safety & Innovation
Obesity & Overweight
UBT251 Injection Phase Ⅲ Study (Overweight or Obesity)
This randomized, double-blind, parallel, placebo-controlled phase Ⅲ study to evaluate the efficacy and safety of UBT251 Injection in overweight/obese patients
- Trial name
- NCT07648225
- Testing
- UBT251 Injection 4.0 mg, UBT251 Injection 6.0 mg
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The United Bio-Technology (Hengqin) Co., Ltd.
Obesity in Diabetes, Type 2 Diabetes Mellitus (T2DM)
A Study to Evaluate the Efficacy and Safety of Once-Weekly MET097 in Adults With Obesity or Overweight and T2DM
This study is designed to test how well once-weekly MET097 (an ultra-long-acting GLP-1 receptor agonist) works to treat adults with obesity or overweight and type 2 diabetes mellitus (T2DM) compared to placebo.
- Trial name
- VESPER-2 (NCT06897202)
- Testing
- MET097 Injection
- Where
- 29 sites in United States
- Volunteers
- 133 people
- Sponsor
- Pfizer
Overweight , Obesity
Efficacy and Safety of ZT006 in Overweight and Obese Participants
This study is being conducted to evaluate the efficacy and safety of ZT006 tablet in participants with overweight and obesity. In addition to dietary caloric restriction and increased physical activity, study participants will…
- Trial name
- NCT07230132
- Testing
- ZT006
- Where
- 12 sites in China
- Volunteers
- 184 people
- Sponsor
- Beijing QL Biopharmaceutical Co.,Ltd
Obesity & Overweight
Long-term Adaptations of Skeletal Muscle After Hybrid Training
Obesity is a major challenge for public health and renders it imperative to reduce its prevalence. High intensity interval training (HIIT) is a form of exercise training that can efficiently induce weight loss in adults with…
- Trial name
- NCT07341711
- Testing
- Exercise training, Control group
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Atrial Fibrillation Ablation, Persistent Atrial Fibrillation
Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial Fibrillation
The goal of this clinical trial is to determine whether tirzepatide can reduce atrial fibrillation (AF) burden after catheter ablation in overweight or obese patients with persistent AF.
- Conditions
- Atrial Fibrillation Ablation, Persistent Atrial Fibrillation, Obesity & Overweight
- Trial name
- TREAT-AF (NCT07382024)
- Testing
- Tirzepatide, Standard Care (in control arm)
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Obesity & Overweight, Obesity (Disorder)
Real-World Case Registry Study on Obesity
Obesity is a major risk factor for cardiovascular disease, diabetes, cancer, and other chronic conditions. Due to its complex etiology and frequent comorbidities, effective obesity management requires comprehensive and…
- Trial name
- NCT07448090
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Hubei Hospital of Traditional Chinese Medicine
Childhood Obesity, Overweight and Obese Children
Development and Evaluation of a Web-based Parental Role Modeling Program for Childhood Obesity Management
The goal of this clinical trial is to learn whether an online family health education program can help Vietnamese children aged 7-9 years with overweight or obesity develop healthier habits.
- Conditions
- Childhood Obesity, Overweight and Obese Children, Pediatric Obesity, Overweight and Obesity in Schoolchildren
- Trial name
- NCT07641452
- Testing
- Web-based parental role modeling program, Standard health education materials
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Do Thi Thu Huyen
Overweight , Obesity
Effect of A Theory-based Multicomponent eHealth Intervention Program
This study is a two-arm pilot randomized controlled trial designed to evaluate the feasibility and preliminary effects of an Acceptance and Commitment Therapy (ACT) theory-based mobile application integrated with a smartphone…
- Trial name
- NCT07644143
- Testing
- Mobile app weight self-stigma program
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University
Overweight , Obesity, Abdominal Obesity-Metabolic Syndrome
Body Weight Reduction and Metabolic/Biochemical Parameters in Overweight or Obesity
This was a single-center prospective observational cohort study conducted in Poland in the context of routine metabolic outpatient care.
- Trial name
- NCT07645105
- Testing
- Routine Lifestyle-Based Weight Reduction Management
- Where
- 2 sites in Poland
- Volunteers
- 53 people
- Sponsor
- Medical University of Silesia
Osteo Arthritis of the Knee, Obesity & Overweight
Alignment Techniques in TKA RCT
The purpose of this research study is to compare two different methods used to align the knee during a total knee arthroplasty (TKA): technology-assisted inverse kinematic alignment, and manual-instrumented gap balancing…
- Trial name
- NCT07646158
- Testing
- Technology-assisted inverse kinematic alignment TKA, Manual-instrumented gap balancing alignment TKA
- Volunteers
- 80 people
- Sponsor
- Jacob M. Elkins
Obesity & Overweight
Comparative Effectiveness of Western Pharmacotherapy Versus Integrative Western and Traditional Chinese Medicine for Weight Management in Central Taiwan: A Real-World Cohort Study
Obesity is a major public health issue. While modern Western pharmacotherapies (e.g., GLP-1 receptor agonists) and Traditional Chinese Medicine (TCM) are utilized for weight management, the comparative effectiveness of their…
- Trial name
- NCT07646457
- Where
- Taiwan
- Volunteers
- 296 people
- Sponsor
- National Yang Ming Chiao Tung University
Survivorship, Cancer
BfedBwell Optimization Pilot
Using the Multiphase Optimization Strategy (MOST) framework, an engineering-based approach to efficiently and systematically develop, optimize, and evaluate behavioral interventions, this study will test three components: (1) 1:1…
- Trial name
- NCT06184256
- Testing
- BfedBwell - Core Curriculum, BfedBwell - 1:1 Counseling, BfedBwell - Behavioral Skills
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Colorado, Denver
Obesity and Overweight, Anemia, Iron-Deficiency
Different Efficacy of IFA Supplementation Among Obese and Non-obese Women
This clinical trial aims to learn if there is a relationship between OWT/OB and IDA in nonpregnant women of reproductive age and its impact on iron supplementation.
- Trial name
- NCT06622551
- Testing
- Iron-folic acid supplement
- Where
- Indonesia
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Griffith University
Obesity & Overweight
Healthy Eating for My Infant: A Community- Informed Infant Obesity Prevention Program Addressing the Impact of Maternal Mental Health on Eating and Feeding
Infants from low-income families are at increased risk for obesity, but obesity prevention programs tailored specifically to the needs of these infants are lacking.
- Trial name
- NCT07284108
- Testing
- Healthy Eating for My Infant (HEMI)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Obesity & Overweight
Efficacy of Center-based Childcare to Mitigate Unhealthy Weight Gain in Preschoolers From Low-income Households During the Summer
Studies show that preschool-age children are especially vulnerable to accelerated weight gain during the summer, with those from low-income households (≤185% poverty level or Medicaid eligible - the target population for this…
- Trial name
- NCT07583459
- Testing
- Childcare
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of South Carolina