Clinical trials: Obesity, Overweight
Dexmedetomidine, Fentanyl
Dexmedetomidine vs Fentanyl on Time to Extubation in Patients Undergoing Laparoscopic Sleeve Gastrectomy
This study aims to compare the efficacy of dexmedetomidine versus fentanyl during general anesthesia for patients with morbid obesity undergoing laparoscopic sleeve gastrectomy.
- Conditions
- Dexmedetomidine, Fentanyl, Time to Extubation, Morbid Obesity
- Trial name
- NCT06052111
- Testing
- Group F (fentanyl group), Group D (dexmedetomidine group)
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Helwan University
Mitochondrial Diseases, Obesity
Muscle OXPHOS and Nutrient Homeostasis
Investigators are recruiting adults (men and women, ages 18 to 65 years, inclusive) with a confirmed genetic diagnosis of mitochondrial disease.
- Trial name
- NCT02920671
- Testing
- Tracer-enhanced oral glucose tolerance test (OGTT*), Muscle MRI, Dual energy x-ray absorptiometry (DXA)
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Anovulation, Obesity
An RCT of Metformin Vs Orlistat in Obese Anovulatory Women
This study aims to investigate the role of the weight reduction agent, Orlistat compared to the Metformin for the management of women who are obese and do not ovulate or have difficulty conceiving.
- Trial name
- NCT00292799
- Testing
- Orlistat Vs Metformin
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Hypertension, Hypercholesterolemia
Effects of Purple Vegetables on Cardiovascular Disease (CVD) Risk Factors
The hypothesis is that richly coloured purple vegetables, rich in polyphenolic compounds including anthocyanins will have higher antioxidant and other biological activities, than more lightly coloured versions of these foods.
- Conditions
- Hypertension, Hypercholesterolemia, Type II Diabetes, Obesity
- Trial name
- NCT01564498
- Testing
- vegetable
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Guelph
Obesity
Metabolically Healthy Obesity: Correlations Between BMI and Metabolic Syndrome Biomarkers
The study team's research fills the gap in the obesity literature where BMI with a cut point of 35 is frequently used to show the association between BMI and metabolic syndrome biomarkers.
- Trial name
- NCT03195712
- Where
- United States
- Volunteers
- 691 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Bariatric Surgery Candidate, Weight Loss
Gastric Plication in Mexican Patients
Between January and December 2012, a total of 40 patients underwent GLP. The study will assess subject excess weight loss (%EWL) following the study procedure at 3, 6, 12, 36 and 60 months.
- Conditions
- Bariatric Surgery Candidate, Weight Loss, Obesity, Morbid
- Trial name
- NCT03210207
- Testing
- GASTROPLICATURE
- Volunteers
- 40 people
- Sponsor
- Instituto Mexicano del Seguro Social
Type 2 Diabetes Mellitus in Obese
Glucagon-like Peptide-1 Agonism With Very Low Calorie Diets
The very-low calorie diet (VLCD) is a highly effective and safe way to rapidly lose significant amounts of weight and dramatically improve blood sugar control in a short period of time (typically 8-12 weeks).
- Trial name
- SemVLCD (NCT05606471)
- Testing
- Semaglutide Pen Injector [Ozempic], Very-low Calorie Diet
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Nottingham
Adiposity, Body Composition, Beneficial
Growth and Body Composition in Breastfed Infants - Study on Age of Introduction of Complementary Foods in Iceland
The purpose of this prospective cohort study is to investigate breast-milk and breastfeeding among infants who are exclusively and partially breastfed at 6 months of age in terms of characteristics that are hypothesised to…
- Conditions
- Adiposity, Body Composition, Beneficial, Growth Acceleration
- Trial name
- IceAge2 (NCT02586571)
- Testing
- Breastfeeding
- Volunteers
- 100 people
- Sponsor
- University of Iceland
Obesity
Randomized Study of Daytime vs. Delayed Eating: Effect on Weight and Metabolism
The purpose of this study is to determine if, controlling for eating and sleep timing, caloric intake, and exercise, daytime vs. delayed eating affects body mass, adiposity, and energy metabolism in healthy adults.
- Trial name
- NCT04414644
- Testing
- Eating Condition
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Childhood Obesity, Childhood Obstructive Sleep Apnea
Co-existent Obstructive Sleep Apnea (OSA) and Obesity: Finding Non-exercise Activity Thermogenesis (NEAT) Targets for Intervention
Rationale: Obesity is an increasing childhood epidemic in Canada. Obstructive sleep apnea (OSA) is a complication of obesity which causes cardiovascular disease, reduced quality of life, and premature death.
- Trial name
- NCT00854334
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Katz, Sherri Lynne, M.D.
Metabolic Syndrome, Obesity
Translation of Pritikin Program to the Community
The broad, long-term aims of this scope of work are to investigate the effects of the Pritikin Program to the general population.
- Conditions
- Metabolic Syndrome, Obesity, Weight Loss, Hypertension
- Trial name
- Prit-TN (NCT03929198)
- Testing
- Healthy Lifestyle
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Washington University School of Medicine
Metabolic Syndrome X
High Density Lipoprotein (HDL) Functionality in Metabolic Syndrome
The aim of the study is to examine the kinetic, anti-oxidant, anti-inflammatory and cellular cholesterol efflux properties of high-density lipoprotein (HDL) in subjects with the metabolic syndrome (MetS) and lean individuals.
- Trial name
- NCT00716300
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Western Australia
Obesity, Diabetes
Effect of GLP-1 Receptor (GLP-1R) Agonists on Cardiac Function and on Epicardial Adipose Tissue (EAT) Volume and on Myocardial TG Content in Obese Diabetics
Glucagon-like peptide-1 (GLP-1) receptor agonist are new treatment of type 2 diabetes, they lower blood glucose level (by enhancement of glucose-dependent insulin secretion and suppression of excess glucagon secretion) and reduce…
- Trial name
- NCT02042664
- Testing
- BYETTA treatment, Metformine
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Obesity, Abdominal, Weight Loss
The Effect of Fermented and Non-fermented Soy Based Food in Appetite and Satiety Biomarker Among Young Obesity
Limited data are available regarding the satiety effects from fermented and non-fermented soy-based food. The aim of this study was to compare fermented (tempeh) and non-fermented soy-based diets high in protein in increasing…
- Trial name
- NCT04425109
- Testing
- meal test response
- Where
- Indonesia
- Volunteers
- 13 people
- Sponsor
- Universitas Diponegoro
Obesity, Insufficient Sleep
Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults
The proposed research aims to reduce obesity-related health disparities by promoting healthy lifestyle behaviors among African Americans (AAs), given the high disease burdens associated with low physical activity, insufficient…
- Trial name
- NCT06226077
- Testing
- sleep extension intervention, contact control intervention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Minnesota
Bariatric Surgery Candidate, Malnutrition
BagEL - Bariatric Patients in Primary Care: Post-operative Nutrition and Lifestyle Management
There is a growing number of patients undergoing bariatric surgery requiring lifelong follow-up. BagEL (Bariatric Patients in Primary Care: Post-operative Nutrition and Lifestyle Management) is a survey to evaluate a newly…
- Trial name
- NCT03792412
- Testing
- Usability Questionnaire
- Where
- Austria
- Volunteers
- 220 people
- Sponsor
- Medical University of Vienna
Overweight in Preschool Age Children, Risk of Overweight in Preschool Age Children
Improving Primary Care to Prevent Childhood Obesity
To determine the extent to which a clinical intervention based on the Chronic Care Model (CCM), compared with the usual care control condition, results in a smaller age-associated increase in body mass index (BMI) over a 1 year…
- Trial name
- NCT00377767
- Testing
- To change structure and roles of primary care teams to optimize prevention of obesity
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis
The Liver Health Study for Patients with NAFLD
The study will investigate whether the level of fat stored in the liver is related to the liver's ability to burn fat.
- Conditions
- Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis, Obesity
- Trial name
- NCT03151798
- Testing
- Phase II: Lifestyle treatment, Phase II: Control treatment, Phase I: Observational studies
- Where
- United States
- Volunteers
- 336 people
- Sponsor
- University of Missouri-Columbia
Obesity
The Effect of a Structured Weight-loss Programme on the Metabolic Profiles of Obese and Overweight Children
Aim: The overall aims of this study to look at what changes are seen overweight and obese (very overweight) children, as they get thinner.
- Trial name
- NCT02608398
- Testing
- no intervention
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Imperial College London
Overweight and Obesity
Opportunities for Food Reformulation
The objective of this study is to determine the independent and additive effects of food texture and energy density on food and energy intake compared to a control condition.
- Trial name
- OffR (NCT05659771)
- Testing
- Food properties manipulation to alter eating behavior and food and energy intake
- Where
- Netherlands
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Wageningen University
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