Clinical trials: Obesity, Overweight
Abdominal Contour Defects
Dose-ranging Study
Dose ranging study
- Trial name
- LIPO-102-CL-11 (NCT01712451)
- Testing
- salmeterol xinafoate, fluticasone propionate, salmeterol xinafoate
- Where
- 6 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Neothetics, Inc
Overweight
Mothers' Thoughts About Kids and Eating
Summary: A few studies have explored the effects of providing parents with health information about their children. However, more information is needed about the relationship between awareness of health information and changes in…
- Trial name
- NCT01087346
- Testing
- Reading Information
- Where
- United States
- Volunteers
- 1,148 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Menopause Surgical, Estrogen Deficiency
The Role of Estrogen in Adipocyte Remodeling Following Surgical Menopause
The overarching aim of this study is to assess the downstream effects of abrupt estrogen deficiency in women undergoing elective bilateral oophorectomy by studying: 1.
- Conditions
- Menopause Surgical, Estrogen Deficiency, Adiposity
- Trial name
- RESUME (NCT03631680)
- Testing
- Bilateral Oophorectomy Surgery
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Overweight and Obesity, Type2diabetes
Assessment of Safety, Tolerability and Drug Levels of Exenatide Implant
The purpose of this study is to evaluate the safety, tolerability and drug levels of an exenatide implant administered subcutaneously.
- Trial name
- LIBERATE-1 (NCT05670379)
- Testing
- Exenatide Implant, Bydureon BCise (exenatide extended release), Semaglutide, 1.0 mg/mL
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vivani Medical, Inc
Pediatric Obesity
Family-based Lifestyle Intervention Program and Carotenoid Supplementation for Children With Obesity
This is a pilot study of children between the ages of 8 to 11 years of age who are obese and participating in an intense family based intervention with a family-focused multi-component lifestyle intervention.
- Trial name
- NCT02060279
- Testing
- Lifestyle intervention and carotenoid supplements
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Morbid Obesity, Bariatric Surgery
Registry on Obesity Surgery in Adolescents
While bariatric surgery is established as a safe and effective alternative with well-defined risks for severely obese adults, little has been published on its use in children.
- Conditions
- Morbid Obesity, Bariatric Surgery, Adolescent Obesity
- Trial name
- ROSA (NCT03203161)
- Testing
- bariatric surgery
- Where
- 3 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Queen Fabiola Children's University Hospital
Obesity
Pharmacokinetic Comparison of Multiple Formulations of Topiramate and Phentermine in Obese Adults
The primary objective of this study is to describe the single- and multiple-dose pharmacokinetic profiles of two novel formulations of topiramate and commercially available immediate release topiramate, all dosed with immediate…
- Trial name
- NCT00518466
- Testing
- topiramate, phentermine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Obesity, Morbid, Obesity and Overweight
The Effect of Laparoscopic Sleeve Gastrectomy on Blood Phoenixin-14 Levels
Obesity is a major global health concern with a rising prevalence and numerous associated comorbidities. For the treatment of severe obesity, bariatric surgery stands as the most effective procedure.
- Trial name
- Morbid Obesity (NCT07004556)
- Testing
- Preoperative blood sampling for determining Phoenixin 14 levels, Postoperative blood sampling for determining Phoenixin 14 levels
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Obesity
Adult Weight, Genetics and Lifestyle Factors
Childhood obesity leads to adulthood obesity, demonstrated in many retrospective and longitudinal studies. Genetics as a predictor of obesity is less established.
- Trial name
- NCT03666156
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 96 people
- Sponsor
- St Mary's University College
Cardiovascular Diseases (CVD), Type 2 Diabetes
Epigenetics and NCD Prevention in Kazakhstan: Personalized Approaches and Biological Age Prediction
This study aims to enhance personalized and preventive care for non-communicable diseases (NCDs) in Kazakhstan by examining epigenetic factors, predicting biological age and reproductive function using machine learning, and…
- Conditions
- Cardiovascular Diseases (CVD), Type 2 Diabetes, Chronic Respiratory Diseases, Obesity (Disorder)
- Trial name
- NCT06953180
- Testing
- Genetic: DNA analysis
- Where
- Kazakhstan
- Volunteers
- 6,720 people, healthy volunteers welcome
- Sponsor
- Asfendiyarov Kazakh National Medical University
Morbid Obesity, GERD
GERD After Sleeve Gastrectomy
The main adverse effect is gastroesophageal reflux disease (GERD), with concern on the development of Barrett's esophagus and esophageal adenocarcinoma in the long term. However, the relationship between SG and GERD is complex.
- Trial name
- NCT05178446
- Where
- Italy
- Volunteers
- 14,362 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Polycystic Ovary Syndrome
Effects of GLP-1 Analogue Combined With Metformin and Metformin on Gonadal and Metabolic Profiles in Chinese Overweight/Obese PCOS Patients With Hyperandrogenemia.
To study the effects of GLP-1 analogues combined with metformin and metformin on gonadal and metabolic profiles in PCOS patients with BMI ≥ 24 in China. 60 cases of overweight PCOS patients were collected from Shengjing hospital.
- Trial name
- NCT04969627
- Testing
- Metformin, Exenatide
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Bing He
Obesity
Virtual Lifestyle Management: Prevention Through the UPMC Patient Portal
Diabetes affects 18 million Americans and costs over $132 billion in both direct treatment and lost productivity per year. It is known that weight loss, improved diet and increased exercise can result in improvement in glucose…
- Trial name
- NCT00409786
- Testing
- Virtual Lifestyle Management (VLM)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Pediatric Obesity, Preventive Medicine
Patient-Clinic-Community Integration to Prevent Obesity Among Rural Preschool Children
The goal of this research study is to compare two enhancements to well-child visits at Geisinger designed to promote family-centered counseling for the prevention of obesity in a high-risk population of rural, lower income…
- Conditions
- Pediatric Obesity, Preventive Medicine, Mentoring, Food Supply
- Trial name
- ENCIRCLE (NCT04406441)
- Testing
- Patient Reported Outcome Well Child Visit, Patient Reported Outcome Well Child Visit + Food Care
- Where
- United States
- Volunteers
- 2,040 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Adult Obesity, Weight Management
MIST (Metabolic Intervention With Semaglutide and THR-β Therapy) Trial
The primary objective of this trial is to evaluate the effect of oral ECC4703 on body weight reduction and in a sub-study on liver fat content as assessed by change in magnetic resonance imaging proton density fat fraction…
- Trial name
- NCT07505303
- Testing
- ECC4703, Semaglutide
- Where
- 15 sites in United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Eccogene
Safety, Healthy Subjects
A Study to Evaluate the Safety and Pharmacokinetics of MEDI0382 in Overweight/Obese Subjects of Japanese or Chinese Descent
This is a phase I, randomized, blinded study to evaluate the safety and pharmacokinetics of MEDI0382 following single dose administration to overweight/obese subjects of Japanese or Chinese descent
- Trial name
- NCT03385369
- Testing
- MEDI0382
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Pharmacological Action, Post Operative Pain
The Postoperative Lidocaine and Ketamine Effects on Morphine Requirement in Bariatric Surgery
The goal of this observational study is to evaluate the quality of postoperative analgesia in a group of obese patients schedule to bariatric surgery under TIVA Opiod-free after to receive lidocaine and ketamine perfusion.
- Conditions
- Pharmacological Action, Post Operative Pain, Opioid Use, Obesity, Morbid
- Trial name
- NCT05591105
- Testing
- Control Group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Tiva Group
Cardiovascular Diseases, Heart Diseases
Diet, Exercise and Cardiovascular Health Among Ethnic Children
To document the patterns of influence or socialization from parents to children in regard to the transmission of cardiovascular disease risk related behaviors such as diet and physical activity.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity
- Trial name
- NCT00005179
- Sponsor
- Augusta University
Type 2 Diabetes, Obesity
Metabolomic Analysis of Hepatic Insulin Resistance
This is a pilot study to show that it is possible to identify the specific types of fats in blood, adipose tissue, and liver tissue.
- Trial name
- NCT01833403
- Testing
- Hyperinsulinemic-euglycemic clamp
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity, Ketogenic Dieting
Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness
To initiate a low-carbohydrate, high-fat (LCHF) or ketogenic dietary (KD) intervention among a cohort of outpatients with either schizophrenia or bipolar illness who also have metabolic abnormalities, overweight/obesity, and/or…
- Conditions
- Obesity, Ketogenic Dieting, Metabolic Syndrome, Bipolar Disorder
- Trial name
- NCT03935854
- Testing
- LCHF, Ketogenic Diet
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Stanford University
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