Clinical trials: Obesity, Prediabetes
Psoriasis, PreDiabetes
Effect of Addition of Pyramidal Exercise to Intermittent Fasting on Dryness of Eye in Pre-diabetic Psoriasis Patients
insulin resistant psoriatic obese patients may complain problems of dryness of eye. Intermittent fasting may improve dryness of eye, obesity, insulin resistance, and psoriasis.
- Conditions
- Psoriasis, PreDiabetes, Obesity, Dry Eye
- Trial name
- NCT06893913
- Testing
- pyramidal training plus intermittent fasting, intermittent fasting
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Pre Diabetes, Obesity
MapTrek to Increase Activity Among Patients at Risk for Type 2 Diabetes
The overarching objective of our work is to provide an inexpensive and scalable m-health tool to increase both volume and intensity of physical activity and reduce sedentary behavior in patients at risk for type 2 diabetes.
- Trial name
- NCT03193229
- Testing
- MapTrek, Fitbit
- Where
- United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Philip Polgreen
Diabetes, Prediabetes
Meta-Analyses of the Effect of Plant Protein Versus Animal Protein on Cardiometabolic Risk
Vegetarian diets have been associated with a reduced risk of preventable diseases such as type 2 diabetes and cardiovascular disease. These effects may be mediated through direct or indirect pathways.
- Conditions
- Diabetes, Prediabetes, Metabolic Syndrome, Dysglycemia
- Trial name
- NCT02037321
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Eating Behavior, Metabolic Syndrome
Study of Eating Patterns With a Smartphone App and the Effects of Time Restricted Feeding in the Metabolic Syndrome
SwissChronoFood - Study of eating patterns with a smartphone app and the metabolic effects of time restricted feeding in metabolic syndrome The purpose of this study is to assess eating patterns among teenagers and adults with a…
- Conditions
- Eating Behavior, Metabolic Syndrome, Obesity, Dyslipidemias
- Trial name
- NCT03241121
- Testing
- Time restricted feeding, Regular dietary advices, Eating patterns
- Where
- 2 sites in Switzerland
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Diabetes, Cardiovascular Diseases
The Effects of Apple Consumption on Cardiovascular Health in Prediabetics and Type 2 Diabetics
The hypothesis of this study is that the daily consumption of 75 g dried apple powder for twelve weeks will improve arterial stiffness and blood pressure by improving endothelial-mediated vasodilation and vascular sympathetic…
- Conditions
- Diabetes, Cardiovascular Diseases, Prediabetes
- Trial name
- NCT02224365
- Testing
- Apple
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Florida State University
Obesity, Hypertension
Food as Medicine: A Quasi-Randomized Control Trial of Healthy Foods for Chronic Disease Management
The purpose of this study is to investigate the effect of providing healthy foods and nutrition education on participants' body weight, blood pressure, and average blood sugar level.
- Conditions
- Obesity, Hypertension, Pre-diabetes, Type 2 Diabetes
- Trial name
- NCT05174078
- Testing
- Medically-tailored meals, Produce box and recipes
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Cleveland Clinic Akron General
Adipose Tissue, Brown, Brown Adipose Tissue
Winter-Swimming and Brown Adipose Tissue Activity in Middel-aged Obese Subjects (WinterBAT).
This study investigates repetitive cold-water exposure on brown fat activity assessed by PET/CT scanning. Furthermore we will assess glucose control upon winter-swimming.
- Conditions
- Adipose Tissue, Brown, Brown Adipose Tissue, Uncoupling Protein 1, Cold Exposure
- Trial name
- WinterBAT (NCT03541096)
- Testing
- Winter Swimming, Control group
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Kristian Karstoft
Obesity; Endocrine, Diabete Type 2
Molecular, Metabolomic and Nutritional Changes After Metabolic Surgery
Obesity is a major risk factor for Type 2 Diabetes (T2D) and cardiovascular diseases, such as hypertension and dyslipidemia. Recently, weight loss surgery (i.e., metabolic or bariatric surgery) has been shown to result in very…
- Conditions
- Obesity; Endocrine, Diabete Type 2, PreDiabetes
- Trial name
- MoMen (NCT05322551)
- Where
- Malaysia
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Malaysia
Cardiovascular Diseases, Metabolic Syndrome
Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health.
DOVE-MET-COME-100 is a single site prescreening survey study designed to identify adults who may be eligible for future industry-sponsored clinical trials.
- Conditions
- Cardiovascular Diseases, Metabolic Syndrome, Obesity, Prediabetes
- Trial name
- NCT07106879
- Testing
- Blood Work
- Where
- United States
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Clindove Research LLC
Overweight, Obesity
Evaluating the Effects of a Diet and Exercise Program in People With Type 2 Diabetes or Prediabetes: (The SHAPE3 Study)
Type 2 diabetes and prediabetes, which are mainly caused by a lack of physical activity and excess weight, put people at an increased risk of cardiovascular disease.
- Conditions
- Overweight, Obesity, Type 2 Diabetes, Prediabetes
- Trial name
- SHAPE3 (NCT00928005)
- Testing
- Weight loss diet, Weight loss diet plus exercise
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Prediabetes
Cocoa and Metabolic Health in Prediabetes
The purpose of this study is to determine the impact of consuming cocoa on blood glucose levels, glucose metabolism, and other markers of pre-diabetes in overweight and/or obese individuals.
- Trial name
- NCT02203240
- Testing
- Cocoa
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Virginia Polytechnic Institute and State University
Obesity, Pre Diabetes
Healthsnap on Epicardial Adipose Tissue Study
The purpose of this research study is to learn about the effectiveness of HealthSnap assessment, to reduce epicardial fat thickness.
- Trial name
- HEATS (NCT03683888)
- Testing
- HealthSnap, dietary counseling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Prediabetic State, PreDiabetes
Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center
The purpose of the study is to assess the feasibility and acceptability of incorporating hands-on nutritional demonstrations to enhance the Diabetes Prevention Program (DPP) curriculum among patients who are at-risk for…
- Conditions
- Prediabetic State, PreDiabetes, Health Knowledge, Attitudes, Practice, Nutrition, Healthy
- Trial name
- NCT06897982
- Testing
- One-arm feasibility pilot of a nutrition intervention to recruit, engage, and retain DPP participants in the safety-net setting in Los Angeles
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Diabetes, Nutrition Disorders
OPTIFIT-Optimal Fiber Trial for Diabetes Prevention
High intake of insoluble fiber is strongly associated with a reduced incidence of diabetes and cardiovascular events in prospective observation studies.
- Conditions
- Diabetes, Nutrition Disorders, Obesity, Overweight
- Trial name
- NCT01681173
- Testing
- Fiber
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- German Institute of Human Nutrition
Weight Loss, PreDiabetes
Diabetes Prevention Program to Treat Overweight and Obesity
The purpose of this study is to demonstrate the efficacy of the diabetes prevention program for the treatment of overweight and obesity within the community pharmacy setting.
- Trial name
- DPP-TOO (NCT05640869)
- Testing
- Modified Diabetes Prevention Program Curriculum
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Auburn University
Diabetes, Prediabetes
Meta-analyses of Pasta as Part of Low Glycemic Index Diets and Adiposity
Pasta is an important example of a food which can lower the glycemic index (GI) of the diet, a property that has been exploited extensively in studies of low GI dietary patterns.
- Conditions
- Diabetes, Prediabetes, Overweight, Obesity
- Trial name
- NCT02961088
- Testing
- Pasta as part of a low GI/GL diet
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obstructive Sleep Apnea
Autonomic Function in Obstructive Sleep Apnea
The purpose of this study is to determine if obstructive sleep apnea (OSA) causes autonomic dysfunction independent of its effects on hyperglycemia.
- Trial name
- NCT00681161
- Testing
- continuous positive airway pressure (CPAP)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Vanderbilt University
Diabetes Mellitus, Cancer
Diabetes Prevention Program Outcomes Study
The Diabetes Prevention Program (DPP) was a multi-center trial examining the ability of an intensive lifestyle or metformin to prevent or delay the development of diabetes in a high risk population due to the presence of impaired…
- Conditions
- Diabetes Mellitus, Cancer, CVD
- Trial name
- DPPOS (NCT00038727)
- Testing
- DPPOS Group Lifestyle, Metformin, DPPOS Boost Lifestyle
- Where
- United States
- Volunteers
- 2,779 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Sleep Deprivation, Obesity
Sleep and Metabolism
The goal of this study is to uncover sleep and circadian mechanisms contributing to adverse metabolic health. The protocol is a 21 day (7 outpatient days, 14 inpatient days) mechanistic randomized-crossover study designed to…
- Conditions
- Sleep Deprivation, Obesity, Glucose Intolerance, Weight Gain
- Trial name
- SAM (NCT05775627)
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Impaired Glucose Regulation, Overweight and Obesity
Fermented Dietary Fiber and Probiotics on Overweight/Obese Patients
This study aims to investigate the efficacy of fermented dietary fiber and probiotics in improving glycemic control and associated metabolic parameters in overweight/obese IGR patients.
- Trial name
- NCT06475573
- Testing
- dietary fiber probiotic beverages, whole grain porridge
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine