Clinical trials: Obesity, Visceral
Obesity
Comparison of Medifast's 5 & 1 Plan to a Food-based Plan of Equal Calories
Portion-controlled meal replacements have been shown to be an effective weight control strategy in overweight and obese individuals.
- Trial name
- NCT01011491
- Testing
- Medifast 5 & 1 Plan for weight loss and weight maintenance, Food-based diet plan for weight loss and weight maintenance
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Medifast, Inc.
Metabolic Syndrome
Study of TNF-Antagonism in Metabolic Syndrome
This study investigates whether blockade of TNF will result in reduced inflammatory indices in patients with the metabolic syndrome
- Trial name
- NCT00409318
- Testing
- Etanercept
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Obesity
South Asian Yoga and Exercise Trial
South Asians have one of the highest rates of heart disease of all populations and a unique and deleterious obesity phenotype of increased body fat and inner-abdominal compared to those of European background.
- Trial name
- SAYET (NCT01766453)
- Testing
- Standard Exercise, Bhangra dance exercise
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Body Weight, Visceral Obesity
Effects of Hydroxytyrosol Administration in Anthropometric Parameters in Overweight and Obese Women
This study aims to investigate the potential effects of the administration of hydroxytyrosol, which is an extra virgin olive oil phenolic compound, in doses 15 milligrams and 5 milligrams daily versus placebo for 6 months in…
- Trial name
- NCT04317079
- Testing
- Hydroxytyrosol, Diet
- Where
- Greece
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Obesity, HIV Infections
A Study to Evaluate CJC 1295 in HIV Patients With Visceral Obesity
This is a multicenter, randomized, placebo-controlled, double-blind, Phase 2 study. Patients will be treated for a total of 12 weeks. There will be a 6 week follow-up period after the treatment period ends.
- Trial name
- NCT00267527
- Testing
- CJC 1295
- Volunteers
- 120 people
- Sponsor
- ConjuChem
Menopause Related Conditions, Sarcopenia
Effects of Time-restricted Eating and Exercise Training on Skeletal Muscle Mass Quantity, Quality and Function in Postmenopausal Women With Overweight and Obesity
The goal of this randomized controlled trial] is to investigate the effects of a 12-week time restricted eating (TRE) and exercise combined intervention, as compared to (i) TRE alone, and to (ii) Caloric Restriction (CR) plus the…
- Conditions
- Menopause Related Conditions, Sarcopenia, Osteoporosis Postmenopausal, Obesity
- Trial name
- NCT05912309
- Testing
- Time Restricted Eating (TRE), Exercise, Caloric Restriction
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- Idoia Labayen
Obesity, Metabolic Syndrome
Effects of Exercise on Abdominal Obesity and Risk Factors for Cardiovascular Disease
The investigators will randomize abdominally obese men and women at increased health risk to one of the following 4 conditions: 1) No-exercise, wait list controls (C), 2) Low volume, low intensity exercise (LVLI), 3) High volume…
- Conditions
- Obesity, Metabolic Syndrome, Cardiovascular Disease
- Trial name
- NCT00955071
- Testing
- Exercise: LVLI, Exercise: HVLI, Exercise: LVHI
- Where
- Canada
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Queen's University
Metabolic Syndrome, Insulin Resistance
Grains Reduce Adiposity and Improve Nutrition Study
Whole grain intake beneficially affects body weight, body fat and glucose metabolism, and the investigators' previous work has shown that a high whole grain intake significantly reduced body fat in the abdominal region as…
- Trial name
- GRAIN (NCT00924521)
- Testing
- Whole grain diet, Refined grain
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Penn State University
Obesity, Insulin Resistance
Effect of Probiotic Co-administration With Omega-3 Fatty Acids on Obesity Parameters and Insulin Resistance
Probiotics are defined as live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. Omega-3 fatty acids belong to the family of polyunsaturated fatty acids.
- Conditions
- Obesity, Insulin Resistance, Insulin Sensitivity, Type2 Diabetes
- Trial name
- ENDO-5 (NCT04201938)
- Testing
- Symbiter-Omega
- Where
- Ukraine
- Volunteers
- 56 people
- Sponsor
- Bogomolets National Medical University
Physical Inactivity, Phosphate Overload
Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity
Studies in mice demonstrated that dietary phosphate (Pi) loading that mimic the level of US adult consumption leads to reduced spontaneous locomotor activity, exercise capacity, and reduced resting metabolic rate when in normal…
- Conditions
- Physical Inactivity, Phosphate Overload, Visceral Obesity
- Trial name
- NCT05147909
- Testing
- Sodium Phosphate, Sodium Chloride
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pediatric Obesity, Insulin Resistance
Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance
The primary objective of this randomized, parallel group, double-blind, placebo-controlled study is to determine whether treatment with metformin enhances insulin sensitivity in a group of ethnically diverse obese…
- Conditions
- Pediatric Obesity, Insulin Resistance, Hyperinsulinemia
- Trial name
- NCT00667498
- Testing
- Metformin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity
Cross Calibration of Two Dual Energy Densitometers and Comparison of Regional Adipose Tissue Measurements by iDXA and MRI
Background: It is important for doctors to know how much fat a person has in his or her body. Machines called DXAs measure how much fat mass and fat-free mass a person has.
- Trial name
- NCT02346474
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Visceral, Obesity
Genes Variability in Obesity and Normal Body Weight Patients.
The goal of this clinical trial is to learn about variability of gene SCD and MT-ATP6 in describe participant population and health conditions.
- Trial name
- NCT05789888
- Testing
- MT-ATP6 mtDNA gene variability in obesity and normal body weight patients., SCD gene variability in obesity and normal body weight patients., Finding TOFI and FOTI phenotypes in participants with obesity and normal weight.
- Where
- Poland
- Volunteers
- 116 people
- Sponsor
- Medical University of Bialystok
Obesity, Insulin Resistance
Regional Fat Depots and Insulin Resistance
The biological basis for insulin resistance associated with obesity is unknown. By studying equally-overweight/obese individuals who are either insulin resistant or insulin sensitive, the investigators will compare…
- Conditions
- Obesity, Insulin Resistance, Diabetes Mellitus Type 2
- Trial name
- NCT01336777
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity, Metabolic Syndrome
Study to Determine the Effects of Human Growth Hormone and Pioglitazone in Overweight, Prediabetic Adults
The purpose of the study was to determine the effects of growth hormone and an insulin sensitizer drug in pre-diabetic adults with excessive amounts of abdominal fat.
- Conditions
- Obesity, Metabolic Syndrome, Impaired Glucose Tolerance
- Trial name
- NCT00352287
- Testing
- Recombinant human growth hormone; pioglitazone
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity
Growth Hormone, Cardiovascular Risk, and Visceral Adiposity
This study will compare growth hormone levels and cardiovascular risk markers in normal weight and overweight women and men. In women and men with increased abdominal weight, growth hormone (GH) versus placebo will be…
- Trial name
- NCT00131378
- Testing
- Nutropin AQ growth hormone
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obesity
The Effect of Intervention With Probiotic K56 on Body Fat Reduction in Obese Subjects
The aim of the present study was to investigate the effect of intervention with Lactobacillus paracasei K56 on body fat, metabolic risk markers,inflammatory markers and gut microbiota composition in obesity.
- Trial name
- NCT05192811
- Testing
- Lactobacillus paracasei K56
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fudan University
Visceral Obesity, Metabolic Syndrome
Polygonatum Sibiricum Reduces Visceral Fat in Obese Adults
This study is being done to find out if a traditional Chinese herb called Polygonatum sibiricum (Huangjing) can help reduce belly fat and improve metabolic health in adults with visceral obesity.
- Trial name
- NCT07759323
- Testing
- Polygonatum sibiricum, Lifestyle Intervention
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Zhejiang Provincial Tongde Hospital
Obesity, Visceral, Cardiovascular Diseases
Impact of Liraglutide 3.0 on Body Fat Distribution
This study is a clinical study to investigate the efficacy of liraglutide compared to placebo in reducing visceral adiposity measured by MRI in overweight or obese subjects at high risk for cardiovascular disease after 40 weeks…
- Conditions
- Obesity, Visceral, Cardiovascular Diseases, Fat Disorder
- Trial name
- NCT03038620
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Overweight and Obesity, Overweight or Obesity
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Obesity
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding obesity.
- Conditions
- Overweight and Obesity, Overweight or Obesity, Obesity, Obesity, Morbid
- Trial name
- NCT04100616
- Testing
- No intervention
- Where
- United States
- Sponsor
- ProgenaBiome