Clinical trials: Obesity, Visceral
Osteoporosis, Postmenopausal, Diabetes Mellitus, Type 2
Effect of GLP-1 Receptor Agonists on Trabecular Bone Score
This study will help determine the effect of Glucagon Like Peptide-1 (GLP-1)receptor agonists on bone strength in postmenopausal women with type 2 diabetes mellitus (T2DM)
- Trial name
- NCT04964388
- Testing
- GLP-1 receptor agonist
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Mississippi Medical Center
Menopause
Midlife Empowerment and Longevity Through Optimizing Wellness
The goal of this observational longitudinal study is to understand how lifestyle behaviours, menopausal symptoms, and digital health data change over time in women experiencing perimenopause or menopause, and to evaluate whether…
- Trial name
- MELOW (NCT07713862)
- Testing
- MELOW
- Volunteers
- 200 people
- Sponsor
- National University Health System, Singapore
Pediatric Obesity, Insulin Resistance
Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance
The primary objective of this randomized, parallel group, double-blind, placebo-controlled study is to determine whether treatment with metformin enhances insulin sensitivity in a group of ethnically diverse obese…
- Conditions
- Pediatric Obesity, Insulin Resistance, Hyperinsulinemia
- Trial name
- NCT00667498
- Testing
- Metformin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity, Visceral, Diet, Healthy
Long-term Benefits of Abdominal Fat Loss in Abdominally Obese Dyslipidemic Patients (SYNERGIE Study)
The objective of this clinical trial is to verify whether the beneficial effects of weight loss on visceral fat measured by computed tomography and metabolic risk factors for coronary heart disease are maintained once high-risk…
- Conditions
- Obesity, Visceral, Diet, Healthy, Cardiometabolic Syndrome, Lifestyle-related Condition
- Trial name
- SYNERGIE (NCT06158191)
- Testing
- Lifestyle modification program
- Volunteers
- 186 people
- Sponsor
- Laval University
Menopause Related Conditions, Sarcopenia
Effects of Time-restricted Eating and Exercise Training on Skeletal Muscle Mass Quantity, Quality and Function in Postmenopausal Women With Overweight and Obesity
The goal of this randomized controlled trial] is to investigate the effects of a 12-week time restricted eating (TRE) and exercise combined intervention, as compared to (i) TRE alone, and to (ii) Caloric Restriction (CR) plus the…
- Conditions
- Menopause Related Conditions, Sarcopenia, Osteoporosis Postmenopausal, Obesity
- Trial name
- NCT05912309
- Testing
- Time Restricted Eating (TRE), Exercise, Caloric Restriction
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- Idoia Labayen
Obesity, Type 2 Diabetes
Evaluation of Intra-Abdominal Fat in Patients With Type 2 Diabetes Using a Non-Invasive Method
The main aim of this study is to compare 2 different measurements of visceral fat that can be easily used in clinical practice (waist circumference versus bioelectric impedance) in relation to known risk factors of coronary…
- Conditions
- Obesity, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- NCT01283113
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Joslin Diabetes Center
Visceral Obesity, Atherosclerosis
Abdominal Fat and Imaging Measurements of Heart Disease
Although it is frequently mentioned in the media that overweight and obesity have reached epidemic proportions worldwide and in this country, some Canadians are perplexed and sometimes confused about the role of obesity in…
- Conditions
- Visceral Obesity, Atherosclerosis, Metabolic Syndrome
- Trial name
- NCT01447745
- Where
- Canada
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Laval University
Esophageal Cancer, Gastric Cancer
Sarcopenia and Visceral Obesity in Esophageal and Gastric Cancer
In line with improvements in oncologic outcome for patients with esophageal cancer, the attritional impact of curative treatment with respect to functional status and health-related quality of life (HR-QL) in survivorship is…
- Conditions
- Esophageal Cancer, Gastric Cancer, Sarcopenia, Sarcopenic Obesity
- Trial name
- NCT03061370
- Testing
- Esophagectomy or Gastrectomy
- Where
- 2 sites in Ireland
- Volunteers
- 317 people
- Sponsor
- St. James's Hospital, Ireland
Gestational Diabetes, Obesity
Comparison of Visceral Adipokines Visfatin, Vaspin and Omentin Levels in Gestational Diabetes Mellitus Pregnant Women
The prevalence of maternal obesity is increasing rapidly worldwide and constitutes an important obstetric problem that increases mortality and morbidity in both mothers and infants.
- Conditions
- Gestational Diabetes, Obesity, Visceral Obesity
- Trial name
- NCT05463237
- Testing
- oral glucose tolerance test, Blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Siirt University
Adiposity
Ectopic Adipose Tissue, Exercise Training and IL-6
Aim: Exercise training improves the risk of cardiometabolic diseases; yet the underlying mechanisms are unclear. Exercise induces release of IL-6 from skeletal muscle.
- Trial name
- NCT02901496
- Testing
- Endurance Exercise Training, Resistance Exercise Training, No Exercise
- Where
- Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obesity, Overweight
Whey Protein Intake With and Without Exercise on Visceral Fat: The P+RISE Study
Dietary manipulation is proving to be an effective lifestyle strategy to combat the obesity epidemic. Increased dietary protein is one effective strategy.
- Trial name
- P+RISE (NCT01960335)
- Testing
- Whey Protein, Whey Protein and Resistance Exericse, Whey Protein and RISE exercise routine
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Abdominal Obesity, Growth Hormone Deficiency
Effectiveness of Growth Hormone Releasing Hormone in Reducing Abdominal Fat in People Who Are Obese
Obesity, a condition that occurs when a person has too much body fat, affects about 31% of people in the United States. It is associated with increased risk of diabetes, high blood pressure, high cholesterol, and cardiovascular…
- Trial name
- NCT00675506
- Testing
- Growth hormone releasing hormone (GHRH) 1-44
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Central Obesity
Effectiveness of High-intensity Interval Training (HIIT) Versus Moderate-intensity Continuous Training (MICT) in Reducing Visceral Fat in Adults With Central Obesity
Obesity is a major risk factor for cardiovascular disease and diabetes as well as all-cause mortality. The prevalence of obesity has continuously increased in most countries and has doubled in over 70 countries since 1980.
- Trial name
- NCT04545320
- Testing
- Usual care control group, HIIT group, MICT group
- Where
- Hong Kong
- Sponsor
- The University of Hong Kong
Diabetes Mellitus, Type 2, Insulin Resistance
Evaluation of Intra-Abdominal Fat Extraction Using HydraSolve T2D™ in Obese Subjects With Type 2 Diabetes
This study will investigate the safety and efficacy of the investigational use of the HydraSolve T2D™ System in improving blood glucose control and insulin resistance in patients with obesity (Class 1, BMI 30-39.9 kg/m2) and type…
- Trial name
- NCT03953963
- Testing
- HydraSolve T2D™
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medality Medical
Obesity
Evaluation of the Effect of Moderate-intensity Physical Activity on Glycemic Variability
Obesity is a major public health problem on the world and Mexico too, in addition the obesity develops chronic non-communicable diseases (NCD) such as type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD).
- Trial name
- NCT02620670
- Testing
- Physical activity of moderate intensity for 3 days
- Where
- Mexico
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Body Composition, Visceral Obesity
Dysfunctional Adiposity and Glucose Impairment
This is a large and comprehensively phenotyped cohort with fasting glycaemia where the predictive value of body composition and anthropometric measures of total and central fat distribution for postprandial carbohydrate…
- Conditions
- Body Composition, Visceral Obesity, Carbohydrate Intolerance, Obesity, Abdominal
- Trial name
- DICAMANO (NCT03506581)
- Volunteers
- 853 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Insulin Resistance, Obesity
Surgical Removal of Visceral Fat Tissue (Omentectomy) Associated to Bariatric Surgery: Effects on Insulin Sensitivity
The intraabdominal fat is associated with insulin resistance, a condition that is in the basis of diabetes, metabolic syndrome and some cardiovascular diseases.
- Conditions
- Insulin Resistance, Obesity, Metabolic Syndrome X
- Trial name
- NCT00545805
- Testing
- Roux-en-Y Gastric Bypass plus total omentectomy, Roux-en-Y Gastric Bypass
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Campinas, Brazil
Overweight and Obesity, Men
High-Intensity Interval Training and Fat Mass Losses
The aims of this study was to compare two isoenergetic HIIT (High-intensity Interval training) programs (cycling vs. running) on body composition, substrate oxidation at rest and during a moderate exercise, muscle functionality…
- Trial name
- RIESLING (NCT05311800)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Obesity
Technical Validation of Lunar iDXA (GE Healthcare) Visceral Fat Tool
The goal of this project is to compare visceral fat measurements derived from Lunar iDXA total body scans and from Computed Tomography (CT) scans of the abdominal region.
- Trial name
- NCT00987298
- Testing
- Visceral fat mass measurement
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
High Flow Nasal Cannula, Body Roundness Index
High Flow Nasal Cannula and Mask Oxygenation in Patients With Visceral Obesity Undergoing Sedated Gastroscopy
During sedated gastroscopy, the insertion of the fiberscope and gastric distension required to perform the examination may induce respiratory depression, airway obstruction, and decreased chest wall compliance.
- Trial name
- NCT07159022
- Testing
- High Flow Nasal Cannula Oxygenation, Face Mask Oxygenation
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital