Clinical trials: Obesity/therapy
Obesity, Morbid
Intragastric Injections of Botox for the Treatment of Obesity
One possible angle for treating obesity could be slowing down the gastric emptying time. By prolonging the gastric emptying time, the person would ideally experience increased sensation of satiety, and in the long run reduce food…
- Trial name
- NCT02035397
- Testing
- Botulinum Toxin Type A, Saline solution
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Norwegian University of Science and Technology
Acute Lymphoblastic Leukemia in Remission, Hodgkin Lymphoma in Remission
Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and Lymphoma
This study is evaluating whether a weight-loss medication (PHEN/TOP) combined with healthy lifestyle counseling is safe, well tolerated, and can help reduce obesity in adolescents and young adults who are in remission from ALL…
- Conditions
- Acute Lymphoblastic Leukemia in Remission, Hodgkin Lymphoma in Remission, Non-Hodgkin Lymphoma in Remission, Cancer Survivorship
- Trial name
- NCT07790913
- Testing
- Phentermine/Topiramate ER, Health Behavior and Lifestyle Counseling
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- St. Jude Children's Research Hospital
Obesity-associated Asthma
Metformin Treatment for Children With Obesity-associated Asthma
The goal of this clinical trial is to learn if metformin can improve asthma control in overweight and obese children with mild, moderate, or severe asthma.
- Trial name
- MOACT (NCT07622290)
- Testing
- Metfomin
- Where
- Qatar
- Volunteers
- 182 people
- Sponsor
- Prof Ibrahim Janahi
Endometrial Cancer
Endoscopic Suture Gastroplasty (ESG) for Treatment of Obese Patients With Endometrial Cancer
Obesity increases the risk of endometrial cancer, with higher Body Mass Index (BMI) leading to a significant increase in both cancer risk and recurrence.
- Trial name
- ESG-ENDO (NCT07397624)
- Where
- 2 sites in Italy
- Volunteers
- 74 people
- Sponsor
- Centro di Riferimento Oncologico - Aviano
Type II Diabetes Mellitus
Prospective Randomized Trials of Gastric Bypass Surgery in Patients With Type II Diabetes Mellitus
Although intensive medical treatment of diabetes has clearly been demonstrated to be worthwhile, it has not been a total success in diabetes treatment for a variety of reasons including lack of response to medication.
- Trial name
- T2DM (NCT00540462)
- Testing
- gastric bypass, sleeve gastrectomy
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Min-Sheng General Hospital
Asthma, Obesity
Reducing Socioeconomic Disparities in Health at Pediatric Visits
This research project is aimed to assess the effectiveness and impact of a pediatric-based intervention aimed at reducing low-income families' unmet material needs (food, housing, employment, childcare, household heat, education…
- Conditions
- Asthma, Obesity, Health Care Utilization, Health Care Disparities
- Trial name
- WECARE01 (NCT02451059)
- Testing
- WE CARE survey, WE CARE Community Resource Handout, Patient Navigator
- Where
- 6 sites in United States
- Volunteers
- 1,205 people
- Sponsor
- Boston Medical Center
Morbid Obesity
The Efficacy of an Inpatient Program for Long-term Weight Maintenance in Children and Adolescents With Morbid Obesity
The major problem in the treatment of morbidly obese children is the long term maintenance of the reduced weight. Maintenance-focused interventions have not been studied enough in adolescents with morbid obesity, neither in…
- Trial name
- NCT01254266
- Testing
- inpatient hospitalization and follow up, inpatient treatment and follow up, bariatric surgery
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Rabin Medical Center
ADHD, Weight Loss
Obesity Treatment Enhanced With Working Memory Training
This study will examine the effects of providing subjects who have attention deficits, with or without a formal diagnosis of attention deficit hyperactivity disorder (ADHD), with Working Memory computerized training and explore…
- Trial name
- Focus (NCT02529397)
- Testing
- Adaptive Working Memory Training, Non-adaptive cognitive training
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Attention-Deficit / Hyperactivity Disorder, Depression
Prevention of Comorbid Depression and Obesity in Attention-deficit/ Hyperactivity Disorder
Depression and obesity are very common among adolescents and young adults with attention-deficit/ hyperactivity disorder (ADHD). However, intervention programmes to prevent these comorbid disorders rarely exist.
- Conditions
- Attention-Deficit / Hyperactivity Disorder, Depression, Obesity
- Trial name
- PROUD (NCT03371810)
- Testing
- Bright light therapy, Physical exercise
- Where
- 4 sites in Germany, Netherlands and 2 more
- Volunteers
- 207 people
- Sponsor
- Goethe University
Sleep Apnea, Obstructive Sleep Apnea
Zonisamide for the Treatment of Obstructive Sleep Apnea in Overweight/Obese Patients
This RCT explores the efficacy of Zonisamide (Zonegran®)on overweight/obese in patients with moderate to severe obstructive sleep apnea.
- Conditions
- Sleep Apnea, Obstructive Sleep Apnea, Obesity
- Trial name
- NCT01765608
- Testing
- Zonisamide, nCPAP
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Göteborg University
Insulin Resistance
Neuromuscular Electrical Stimulation: A Novel Treatment for Improving Metabolism
Once written consent is obtained, the participant will be provided with an accelerometer to be worn for 7 days to assess current physical activity levels.
- Trial name
- NCT06722391
- Testing
- Neuromuscular Electrical Stimulation (Sensory), Neuromuscular Electrical Stimulation, Resistance Training
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Obesity
Effect on Energy Metabolism at Cellular Level of Diet Plus Treatment With Ephedrine and Caffeine in Obesity
Brief Summary This trial was part of a sub-project targeted to diet, thermogenesis and obesity of a larger multicentre study named "Interaction between nutritional, social-behavioral and metabolic factors for prevention of…
- Trial name
- NCT02048215
- Testing
- Caffeine, Ephedrine, Hypocaloric diet
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Istituto Auxologico Italiano
Obesity
A Study to Learn About Safety and Effects of Once-monthly Treatment With Berobenatide in Adults With Obesity Disease in Japan (VESPER-JM)
The purpose of this clinical study is to learn about safety and effects of berobenatide (PF-08653944) in adults with obesity disease, a condition in which a person has too much body fat, which can harm their health and increase…
- Trial name
- NCT07794774
- Testing
- Berobenatide
- Where
- 28 sites in Japan
- Volunteers
- 197 people
- Sponsor
- Pfizer
Obesity
Comparison of Weight Loss Induced by Bariatric Surgery vs Conventional Treatment
Patients with overweight or obesity are in need to loose weight and represent a particularly challenging medical condition. Undoubtedly, any intervention achieving a negative energy balance over an extended time period will…
- Trial name
- NCT01572090
- Testing
- Lifestyle Changes, Adjustment of oral antidiabetics/insulin therapy, Laparoscopic sleeve gastrectomy
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Obese Patients
Intragastric Balloon for Treatment of Overweight and Obesity: Which is the Best Filling Volume?
TITLE: Randomized study conducted in a single center, with the aim of comparing the three main filling volumes of the intragastric balloon in overweight or obese patients (BMI >27 and <60 kg/m2).
- Trial name
- NCT06673550
- Testing
- Intragastric balloon
- Where
- Italy
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Mater Olbia Hospital
Obesity, Exercise
Research on Prevention, Intervention and Mechanisms of Obesity and Its Comorbidities
Obesity and lack of physical activity are associated with an increased risk of many chronic diseases and accelerate the processes associated with aging.
- Conditions
- Obesity, Exercise, Nutrition, Healthy
- Trial name
- Obesity (NCT05211817)
- Testing
- Complex lifestyle intervention, Carnosine
- Where
- Slovakia
- Volunteers
- 60 people
- Sponsor
- Slovak Academy of Sciences
Hypogonadism
Testosterone Replacement in Men With Diabetes and Obesity
The purpose of this study is to examine the effect of having testosterone deficiency in men with diabetes and with obesity. The study will also evaluate the effect of testosterone therapy.
- Trial name
- NCT01127659
- Testing
- testosterone
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- University at Buffalo
Obesity
Cardiovascular Treatment
Exercise training is proved to protect against premature cardiovascular mortality. Additionally there is evidence that relatively high exercise intensity may be an important factor for improving aerobic capacity and endothelial…
- Trial name
- NCT00839579
- Testing
- 1x4 min interval
- Where
- Norway
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Impact of Cooking Workshops on Obese Adults
Impacts of Remote Cooking Workshops on Patients With Obesity (CuisTO)
The implementation of therapeutic cooking workshops during the management of obesity in hospitals is now well accepted and recognized as of potential interest on the nutritional level but also cognitive and social (DESPORT, 2015…
- Trial name
- CuisTO (NCT05693506)
- Testing
- Cooking workshops
- Where
- 6 sites in France
- Volunteers
- 420 people
- Sponsor
- Centre Hospitalier FH Manhes
Metabolic Syndrome
Therapeutic Effect of Green Seaweed Against Metabloc Syndrome
Metabolic syndrome is a major concern worldwide and in Pakistan as well. Metabolic syndrome is a pathologic condition which includes abdominal obesity, insulin resistance, hypertension and hyperlipidemia.
- Trial name
- NCT05786534
- Testing
- Green Seaweed
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan