Clinical trials: Obesity; Overweight
Overweight and Obesity
The Feasibility and Preliminary Efficacy of the Mindful-Healthy Family Intervention With Rural Families
This two-group RCT, the Mindful-Healthy Family project, will test the feasibility and preliminary efficacy of a mindfulness-based Motivational Interviewing (MM-based-MI) intervention with rural families within Michigan.
- Trial name
- MHFproject (NCT05324969)
- Testing
- MM-based MI, healthy education
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Hypoxia, Hysteroscopy
The Effects of Remimazolam on the Incidence of Severe Hypoxia During Sedated Hysteroscopy for Assisted Reproduction in Overweight or Obese Patients
Hypoxia is a common adverse event during sedated hysteroscopy for assisted reproduction, and it is more likely to occur in overweight or obese patients.
- Conditions
- Hypoxia, Hysteroscopy, Overweight or Obesity
- Trial name
- RP (NCT06187896)
- Testing
- remimazolam, Propofol
- Where
- China
- Volunteers
- 600 people
- Sponsor
- RenJi Hospital
Test Meal
Fructose Extra-splanchnic Metabolism and Its Effects on Systemic Flux of Substrates (FruPP)
In parallel to the dramatic rise in metabolic diseases and diabetes observed over the past fifty years, the generalization of added sugar in processed food led to a marked increase in fructose consumption in almost all countries…
- Trial name
- FruPP (NCT03195062)
- Testing
- Test meal
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Morbid Obesity, Gastroesophageal Reflux
MGB/OAGB and LSG Effects on Lower Esophageal Sphincter (LES) Function
Background While several articles have reported about the effects of laparoscopic sleeve gastrectomy (LSG) on the lower esophageal sphincter (LES), to date, just one paper has discussed this issue with regard the Mini/One…
- Conditions
- Morbid Obesity, Gastroesophageal Reflux, Bariatric Surgery Candidate
- Trial name
- NCT02987673
- Testing
- MGB/OAGB, LSG
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Mario Musella MD
Childhood Obesity
Obesity Prevention in Head Start
Family style dining is a widely-advocated approach by which to feed children in early education settings. While family-style dining is hypothesized to allow children to attend to their hunger and satiety and consume only the…
- Trial name
- NCT03672227
- Testing
- Mealtime Matters Training
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Severe Obesity, Hypoxia
Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures
The study evaluated the effect of non-invasive positive pressure ventilation (NIPPV) to decrease the incidence of desaturation events in patients with severe obesity undergoing upper endoscopy.
- Trial name
- NCT03529461
- Testing
- Non-invasive positive pressure ventilation through nasal mask, Rescue non-invasive positive pressure ventilation through nasal mask, Secondary rescue maneuvers
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bristol Hospital
Obesity
Collaborative Multi-level Obesity Intervention Engaging Communities Trial
The goal of this clinical trial is to test the effectiveness of an evidence-based multi-level intervention for weight loss and the feasibility, fidelity, and sustainability of implementing the intervention in people living with…
- Trial name
- CONNECT (NCT06835686)
- Testing
- Health Literacy and Culturally Tailored Materials, Community-Engaged Health Coaching and Navigation, Self-Monitoring and Remote Patient Monitoring of weight and physical activity
- Where
- 18 sites in United States
- Volunteers
- 522 people
- Sponsor
- Tulane University
Obesity, Insulin Resistance
Capsaicin Energy Expenditure and Glucose Metabolism
The aim of the study is to investigate the effects of capsaicin rich foods on resting energy expenditure and substrate oxidation.
- Trial name
- CAPS (NCT03859583)
- Testing
- Capsaicin, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Mason University
Dyslipidemia, Obesity &Amp; Overweight
Improvement and Safety of Nutrilite Protein MetX Pro on Weight Management in Overweight Individuals With Dyslipidemia
The goal of this randomized, double-blind, placebo-controlled, single center study is to evaluate the impact of Nutrilite Protein MetX Pro (the study product, a high-protein compound beverages supplemented with multiple plant…
- Trial name
- NCT07094022
- Testing
- Nutrilite Protein MetX Pro
- Where
- 2 sites in China
- Volunteers
- 66 people
- Sponsor
- Amway (China) R&D Center
Pre-obesity, Obesity
DIGITALIZATION OF PERSONALISED HEALTH RISK MANAGEMENT
The principal objective of the project is: to bring together academic and business research organisations in a joint partnership integrating technological and social innovation, in order to develop proof-of-concept of a scalable…
- Trial name
- DIG4HEALTH (NCT06983431)
- Testing
- technology driven self coaching, Health coaching, Peer coaching
- Where
- Slovakia
- Volunteers
- 320 people
- Sponsor
- Slovak Academy of Sciences
Obesity; Excess Calories
Speed Limits: Food Intake and Eating Behaviour of Ultra-processed and Unprocessed Foods
Rationale: Foods that can be eaten at a fast rate - with low mastication effort - lead to shorter orosensory exposure (OSE) per unit of food consumed.
- Trial name
- Vogue (NCT04280146)
- Testing
- daily energy intake
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Obesity
Comparison of Storz C-MAC and D-MAC Orotracheal Intubation Systems in Morbidly Obese Patients
The investigators hypothesize that the D-MAC (Dblade with C-MAC system) may be a suitable alternative device for difficult laryngoscopy and tracheal intubation in morbidly obese patients.
- Trial name
- NCT01556061
- Testing
- DMAC, CMAC
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Obese
Changes in Intrahepatic Lipids With Exercise
Individuals with obesity and particular type 2 diabetes have abnormally high levels of fat in liver cells and are at increased risk for cardiovascular and liver-related mortality.
- Trial name
- NCT02181270
- Testing
- high intensity exercise, continuous moderate exercise
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Healthy
Diet, Exercise and Body Fat in 3-5 Year Olds
To determine how practical and precise different body composition methods are for measuring body fat and lean tissue in young children and to determine if certain dietary factors and physical activity patterns are related to body…
- Trial name
- NCT00615641
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Obesity
A Pilot Trial of Nabilone for the Treatment of Obesity
Obesity is a serious health problem which increases the likelihood of developing other life-changing medical conditions. Despite increasing knowledge about the neural and metabolic basis of obesity, the development of effective…
- Trial name
- NCT04801641
- Testing
- Nabilone
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Centre for Addiction and Mental Health
Obesity, Obesity With Complications
Prevalence, Determinants and Consequences of Dyspnea During Weaning in Critically Ill Obese Patients
ICU patients encounter numerous discomforts, with dyspnea (the sensation of breathlessness) being among the most distressing and impactful.
- Conditions
- Obesity, Obesity With Complications, Weaning From Mechanical Ventilation in Care Unit, Dyspnea
- Trial name
- WEAN OBESE (NCT06867354)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity, Brain Function
Food Intake-Related Brain and Metabolic Responses in Obesity
This study is a prospective, single-center, randomized, controlled, crossover intervention trial. A total of 60 participants, including 30 patients with obesity and 30 healthy controls, will be enrolled.
- Conditions
- Obesity, Brain Function, Metabolomics, Feeding Behavior
- Trial name
- NCT07392905
- Testing
- Glucose Liquid Meal, Fat Liquid Meal, Protein Liquid Meal
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Energy Expenditure, Body Composition
The Energy Cost of 1-Hour Football Training
This study aims at investigating the energy expenditure following a single Football trainning session in middle aged males. The participants will perform a soccer training session [A single training session including 60 minutes…
- Conditions
- Energy Expenditure, Body Composition, Resting Metabolic Rate, Overweight and Obesity
- Trial name
- FAM (NCT06477705)
- Testing
- FAM
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Obesity
Effectiveness of Differing Levels of Support for Family Mealtimes on Obesity Prevention Among Head Start Preschools
Socioeconomic disparities in early childhood place low-income children at 1.5 to 2 times higher risk for obesity compared to middle- to upper-income children.
- Trial name
- SimplyDinner (NCT02487251)
- Testing
- Mealtime Supports, Usual Exposure
- Where
- 4 sites in United States
- Volunteers
- 810 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Obesity
Identify Bacteria Associated With Metabolic Diseases That Reside Both in Intestinal Crypts and in Blood
The investigators will compare 16sRDNA profile in cases and controls in order to identify bacteria associated with metabolic diseases that reside both in intestinal crypts and in blood.
- Trial name
- MICIMAB (NCT02261831)
- Testing
- obese patients, diabetic patients, patients free of obesity and diabetes
- Where
- France
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse