Clinical trials: Obesity; Overweight
Obesity
Preventing Obesity in the Worksite: A Multi-Message, Multi-"Step" Approach
The purpose of this research study is to develop, implement, and evaluate a multi-component obesity prevention program in a workplace setting.
- Trial name
- Go! (NCT01585480)
- Testing
- Weight Gain Prevention Intervention
- Where
- United States
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Diabetes, Hypertension
Management of Patients With Type 2 Diabetes and Hypertension Using Mobile Health Care System
The purpose of this study is to determine whether cellular phone based health care system is effective in the treatment of diabetes and hypertension.
- Conditions
- Diabetes, Hypertension, Obesity
- Trial name
- NCT00489879
- Testing
- Mobile Health Care System (DrUB)
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- Korea University
Overweight, Weight Loss
Weight Loss Interventions for Obesity
Numerous barriers towards weight management among Singaporeans with obesity exists, which involves environmental and self-regulation factors (i.e. motivation and hunger).
- Conditions
- Overweight, Weight Loss, Ketogenic Dieting, Obesity
- Trial name
- NCT06022796
- Testing
- Healthy Ketogenic Ready-to-Eat Meals, Healthy Ketogenic Diet
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Atherosclerosis
The Role of R-Alpha Lipoic Acid in the Treatment of Atherosclerotic Vascular Disease
The purpose of this study is to see if a dietary supplement, R-alpha lipoic acid, is able to reduce risk factors in people with documented heart disease and increased levels of inflammation.
- Trial name
- NCT00764270
- Testing
- R-alpha lipoic acid
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Oregon State University
Obesity
Neurohormonal & Behavioral Correlates of Obesity and Weight Loss
Obesity has reached epidemic levels in the United States, and is on the rise in many industrialized nations. The rate of recidivism for long-term weight loss is substantial and presents a critical problem given the importance of…
- Trial name
- NCT02063451
- Testing
- Very Low Calorie Diet (VLCD)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obesity, Adolescent
Nutrition Goes to School: a School-based Nutrition Intervention to Promote Healthy Eating Behaviour Among Adolescents
The goal of this cluster randomized controlled pilot trial is to assess the feasibility and effect of a school-based nutrition intervention program called "Nutrition Goes to School" (NGTS) in improving a healthy diet and physical…
- Trial name
- ESTEEM-NGTS (NCT06515288)
- Testing
- Nutrition Goes To School (NGTS) Program Intervention Package, Nutrition Education Capacity Building for Teachers and Management
- Where
- Indonesia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition
Overweight and Obesity
A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity
The purpose of this study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of ascending doses of WVE-007 when administered subcutaneously (SC) .
- Trial name
- INLIGHT (NCT06842186)
- Testing
- WVE-007
- Where
- 7 sites in United States, Moldova and 2 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Wave Life Sciences USA, Inc.
Morbid Obesity
Laparoscopic Sleeve Gastrectomy Short Term Follow up
Laparoscopic Sleeve Gastrectomy (LSG), Also known as longitudinal or vertical gastrectomy. LSG was initially considered a first-stage operation in high-risk patients before bilio-pancreatic diversion or Roux-en-Y gastric bypass…
- Trial name
- NCT03465956
- Testing
- Laparoscopic Sleeve Gastrectomy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mohamed Gamal Thabet
Overweight, Obesity
A Study of LY3457263 in Obese Participants
The main purpose of this study is to evaluate the safety and tolerability of LY3457263 when administered in combination with tirzepatitide in overweight or obese participants.
- Trial name
- NCT05582096
- Testing
- LY3457263, Tirzepatide
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Obesity, Childhood
Teens Committed to Health Through Activity, Relationships, and Good Eating
This study will evaluate the preliminary efficacy of a school-based weight management program for underserved adolescents. The program was designed with a phased treatment structure to provide more intensive treatment to…
- Trial name
- Take CHARGE! (NCT04362280)
- Testing
- ReCHARGE, TAU
- Where
- United States
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- University of Houston
Non-alcoholic Fatty Liver Disease, Morbid Obesity
Ursodeoxycholic Acid in Bariatric Surgery
In an open-label trial, 20 otherwise healthy morbidly obese patients scheduled for bariatric surgery will be administered 20 mg/kg/day ursodeoxycholic acid for three weeks until the day before surgery.
- Trial name
- NCT01548079
- Testing
- Ursodeoxycholic Acid (UDCA)
- Volunteers
- 40 people
- Sponsor
- Sahlgrenska University Hospital
Cardiovascular Diseases, Heart Diseases
Cafeteria-Based Study of Weight Gain Prevention
To investigate two cafeteria-based methods of weight gain prevention in overweight men and women.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity
- Trial name
- NCT00142662
- Testing
- diet, financial incentives
- Sponsor
- Drexel University
Spinal Anesthesia, Ultrasound Assistance
Spinal Anesthesia Using Ultrasound Assistance Versus Conventional Palpation in Morbidly Obese Patients
The aim of this study is to compare the paramedian approach for spinal anesthesia using ultrasound assistance (USAS) versus conventional palpation in morbidly obese patients undergoing elective surgeries.
- Conditions
- Spinal Anesthesia, Ultrasound Assistance, Obesity, Morbid
- Trial name
- NCT05240846
- Testing
- Paramedian conventional palpation group, Ultrasound assistance paramedian spinal group
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Kafrelsheikh University
Obesity, Morbid Obesity
Long Term Effect of Very-low-calories Ketogenic Diet on Weight Control and Cardiovascular Brisk Factors (KETOHEART)
The growing obesity pandemic has a major impact on global cardiovascular (CVD)-related morbidity and premature mortality, severely compromising the quality of life of those affected and significantly increasing costs for the…
- Trial name
- KETOHEART (NCT05781269)
- Testing
- VLCKD, r-MedDiet
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Veterans, Obesity
An M-Health Intervention in Rural Veterans
MapTrek is a mobile-phone-based web app that allows participants to take a virtual walk in interesting locations around the world while tracking their progress against the progress of other veterans on an interactive map.
- Conditions
- Veterans, Obesity, Overweight
- Trial name
- NCT03720054
- Testing
- MapTrek, Fitbit
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- University of Iowa
Binge Eating Disorder
Integrative Cognitive-Affective Therapy for Binge Eating Disorder
The purpose of the study is to test a newly developed individual psychotherapy treatment for binge eating disorder in adults. This treatment is a type of individual psychotherapy called Integrative Cognitive-Affective Therapy…
- Trial name
- NCT02043496
- Testing
- Integrative Cognitive-Affective Therapy, CBT-Guided Self Help
- Where
- 2 sites in United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity, Stress
Seasonal Patterns of Stress, Diet and Physical Activity - Life in All Seasons (LENAS)
The purpose of this study is to develop a better understanding of factors affecting American's energy balance related behaviors - in this case, food intake and activity.
- Conditions
- Obesity, Stress, Feeding Behavior, Physical Activity
- Trial name
- LENAS (NCT01674296)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Overweight, Obesity
Energy Expenditure and Substrate Oxidation in a Whole Room Calorimeter
The investigators aim to establish a protocol for metabolic rate measurements obtained using continuous monitoring of oxygen consumption and carbon dioxide production in a whole room calorimeter setting.
- Conditions
- Overweight, Obesity, Body Weight
- Trial name
- NCT04061369
- Testing
- Low fat meal, Moderate fat meal, High fat meal
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Overweight and Obesity, Overweight Adolescents
Breakfast for Young Females
Investigators will test the health effects of eating a dairy-based protein-rich breakfast or isocaloric breakfast and performing regular physical exercise training for 12 weeks in young overweight women (2 x 2 factorial design).
- Conditions
- Overweight and Obesity, Overweight Adolescents, Metabolic Disease
- Trial name
- NyStart2 (NCT04518605)
- Testing
- Low protein breakfast, High protein breakfast, Exercise training
- Where
- Denmark
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy, Obese
Circadian Rhythmicity in Cold-induced Thermogenesis
This study aims to investigate whether maximum cold-induced non-shivering thermogenesis (e.g. thermogenesis as a consequence of BAT activity) differs between morning and evening.
- Conditions
- Healthy, Obese, Glucose Intolerance
- Trial name
- COLDR (NCT04406922)
- Testing
- Personalized cooling protocol
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center