Clinical trials: Obesity; Overweight
Meralgia Paresthetica
Pulsed Radiofrequency of Lateral Femoral Cutaneous Nerve
In the current retrospective cohort study, conducted by both pain specialists and neurophysiologists, the primary outcome was to search for the effect of obesity on the efficacy of PRF of LFCN in refractory MP for 6 months.
- Trial name
- NCT06187883
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Mersin Training and Research Hospital
Type 2 Diabetes, Overweight and Obesity
Episodic Future Thinking to Improve Management of Type 2 Diabetes: Remote Delivery and Outcomes Assessment
Successful management of type 2 diabetes (T2D) requires adherence to a dietary, physical activity, and medication plan agreed upon between a patient and their healthcare providers.
- Trial name
- NCT05280925
- Testing
- Episodic Future Thinking, Healthy Information Thinking
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Virginia Polytechnic Institute and State University
Adiposity
Myokine Identification Following Acute Exercise
Exercise stimulates a cascade of responses within the human body. For example, exercise results in the release of proteins into the circulation which communicate with cells and organs throughout the body.
- Trial name
- NCT06223035
- Testing
- Exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Overweight and Obesity, Healthy Diet
Acute Intervention to Assess the Impact of Practical Strategies for Healthy Eating
Obesity has reached epidemic proportions globally, alongside its associated comorbidities including cardiovascular diseases, diabetes and cancer.
- Trial name
- PORTIONS-3 (NCT05619276)
- Testing
- Standard serving utensil toolkit, Optimsed portion-control toolkit
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Allergies, Obesity
Effects of the Mediterranean Diet During Pregnancy on the Onset of Allergies in the Offspring
Allergy prevalence is increasing steadily with some describing as the "epidemic of the twenty-first century". Maternal diet during pregnancy has been linked to offspring allergy risk, so it represents a potential target for…
- Conditions
- Allergies, Obesity, Gestational Complications, Gestational Weight Gain
- Trial name
- PREMEDI (NCT05119868)
- Testing
- Nutritional intervention based on Mediterranean Diet
- Where
- 2 sites in Italy
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Federico II University
Obesity, Abdominal
Nicotinamide Adenine Dinucleotide (NAD+) Metabolism in Human Brown Adipose Tissue
A fully functional brown fat helps maintain a healthy weight and decreases the risk of metabolic diseases such as type II diabetes (T2DM).
- Trial name
- BATNAD (NCT06627868)
- Testing
- NAD+ precursor
- Where
- Finland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Turku
Type2 Diabetes Mellitus, Obesity
Neujia Anastomosis for Treatment of Obesity and Type II Diabetes
This prospective, multicenter, open label, single arm study will enroll subjects presenting with obesity and inadequately controlled type II diabetes (T2DM).
- Trial name
- NEUJIA 1A (NCT03675074)
- Testing
- Neujia
- Sponsor
- Neurotronic, Inc.
Obesity
Acupuncture for Obesity on Serum Metabolic Parameters
This research is planned to build a basis about the effect of acupuncture on serum metabolic parameters in pre-menopausal obese women with economic evaluation.
- Trial name
- NCT02066090
- Testing
- Real acupuncture
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Obesity
Reduction of Emotional Eating After a Behavior Change Program in Obesity
Recent studies show that overweight people have a greater sensitivity to the rewarding aspect of food due to the disturbance of the dopaminergic system.
- Trial name
- NCT01997697
- Testing
- behavior change program
- Where
- France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Montpellier
Obesity, Metabolically Healthy Obesity
Exercise and Diet Responses in Adult Men With Obesity by MC4R Genotype and Metabolic Health
This study evaluated whether differences in the MC4R rs17782313 gene variant and metabolic health status were associated with different responses to a 12-week exercise and dietary intervention in adult men with obesity.
- Conditions
- Obesity, Metabolically Healthy Obesity, Metabolically Unhealthy Obesity
- Trial name
- NCT07750197
- Testing
- Supervised Aerobic and Resistance Exercise
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Harbin Sport University
Asthma, Overweight
Weight-reduction Intervention in Asthmatic Children With Overweight/Obesity
The purpose of this study is to determine the efficacy of a multifactorial intervention with weight reduction, behavioural therapy, and physical exercise on the severity and control of asthma in obese children.
- Conditions
- Asthma, Overweight, Obesity
- Trial name
- NCT00998413
- Testing
- Multifaceted intervention
- Where
- 2 sites in Netherlands
- Volunteers
- 87 people
- Sponsor
- Maastricht University Medical Center
Obesity
Transduction of Sympathetic Neural Activity in Human Obesity Without Hypertension
In addition to chronically elevated MSNA, there is a growing recognition that hypertension in states of insulin resistance and obesity may also be attributed to an increased vascular sensitivity to MSNA (1, 2, 13, 36-38).
- Trial name
- NCT06626113
- Testing
- ascorbic acid
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Kansas Medical Center
Obesity and Overweight
Study of Patients Being Treated With Anti-obesity Medication
The goal of this observational study is to learn about the real-world effects of selected obesity medications in adults undergoing medical weight management.
- Trial name
- NCT06790160
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Texas Tech University
Obesity, Type 2 Diabetes
Epigenetic Effects of a Single Bout of Exercise on Cardiovascular Risk Factors and the Metabolome
The purpose of this study is to determine the ability of acute exercise to regulate fat metabolism in muscle of overweight and obese people compared to lean people.
- Conditions
- Obesity, Type 2 Diabetes, Cardiovascular Diseases, Acute Exercise
- Trial name
- NCT05034380
- Testing
- Acute exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Cardiovascular Diseases, Heart Diseases
Preventing American Indian Children From Becoming Overweight
The purpose of this study is to establish an intervention to keep American Indian/Alaskan Native (AI/AN) children from becoming overweight.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity
- Trial name
- NCT00245180
- Testing
- Diet, Exercise
- Volunteers
- 577 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obesity, Hypertension
Tongzhou Cohort Study
Long-term Impact of Overweight/Obesity and Hypertension on Cardiovascular Risk in Middle-aged and Elderly Adults
- Trial name
- NCT05156580
- Testing
- No intervention
- Where
- China
- Volunteers
- 31,080 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Lumbar Spinal Stenosis, Obesity
The Spinal Stenosis Pedometer and Nutrition e-Health Lifestyle Intervention (SSPANLI) Trial
Obesity is one of the most important determinants of quality of life and function. People with lumbar spinal stenosis may be at increased risk of obesity given walking limitations.
- Trial name
- SSPANLI (NCT01902979)
- Testing
- Lifestyle intervention
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- Mount Royal University
Overweight or Obese, Type 2 Diabetes Mellitus (T2DM)
A Study of Enicepatide (CT-388) in Participants Who Are Overweight or Obese With Type 2 Diabetes Mellitus
This is a multi-center, randomized, double-blind, placebo-controlled, parallel group dose-finding study to evaluate the efficacy and safety of enicepatide at low, middle, and high doses in participants who are overweight or obese…
- Trial name
- NCT06628362
- Testing
- Enicepatide
- Where
- 70 sites in United States, Argentina and 4 more
- Volunteers
- 447 people
- Sponsor
- Carmot Therapeutics, Inc.
Arterial Embolization, Other Surgical Procedures
Gastric Artery Embolization Trial for Lessening Appetite Nonsurgically
The purpose of this pilot study is to achieve the collection of safety and efficacy data in patients undergoing left gastric artery embolization for morbid obesity in the United States.
- Conditions
- Arterial Embolization, Other Surgical Procedures, Obesity
- Trial name
- GETLEAN (NCT02248688)
- Testing
- BeadBlock 300 - 500 Micron, Left Gastric Artery Embolization
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Dayton Interventional Radiology
Healthy Women
Timing of Food Intake Impacts Daily Rhythms of Human Saliva Microbiota
The purpose of this investigation is to test the hypothesis that in humans, eating late may induce changes in saliva microbiota daily rhythms towards a more obesogenic and a less responsiveness to dietary treatments profile.
- Trial name
- ONTIME-MIC (NCT03147703)
- Testing
- Food Timing
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia