Clinical trials: Obesity, suspended
Obesity, Bariatric Surgery Candidate
Perioperative Systemic Lidocaine for Enhanced Bowel Recovery After Bariatric Surgery
Increasing rates of obesity over the last few decades have led to growing demand for bariatric surgery, which may resulted in decreased comorbidities and improved patient outcomes.
- Trial name
- NCT02607488
- Testing
- Lidocaine 1%, Lidocaine 1.5%, Lidocaine 2%
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Mansoura University
Metabolic Surgery
Could Single-anastomosis Gastric Bypass Be a Curative Treatment for Type II Diabetes?
Single- Anastomosis gastric bypass (SAGB) is a potentially curative line of treatment for type II diabetes mellitus (T2DM) patients with BMI 25-30 kg/m2. Accordingly, SAGB could be integrated into T2DM treatment algorithm
- Trial name
- NCT03412253
- Testing
- Single-Anastomosis Gastric Bypass surgery (SAGB).
- Volunteers
- 17 people
- Sponsor
- Ain Shams University
Obesity
Effect of a Physical Activity Program on the Hormonal Regulation of Food Intake
The primary purpose of this protocol is to assess the hormonal regulation of satiety by an intense exercise before and after a 3 month physical activity program.
- Trial name
- APHRO (NCT01824680)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Polycystic Ovary Syndrome, Insulin Resistance
Endocrine and Menstrual Disturbances in Women With Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive age women, which causes disordered follicle growth and ovulation resulting in infertility.
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Vitamin D Deficiency, Obesity
- Trial name
- EMDPCOS (NCT03652987)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- St George's, University of London
Impulsive Behavior
Transcranial Direct Current Stimulation for Impulsivity and Food-related Impulsivity in Obesity
In this study the investigators aim to assess whether transcranial direct current stimulation (tDCS; a safe non-invasive method for modulating the activity of specific brain regions) when applied over the orbitofrontal cortex…
- Trial name
- tDCS (NCT04218383)
- Testing
- Transcranial Direct Current Stimulation
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Overweight and Obesity
Fixed Dose Combination of Fluoxetin and Metformin in the Management of Overweight and Obesity
Clinical trial, multicenter, double-blind, placebo-controlled, comparative of three parallel groups, randomized treatment to assess the efficacy and safety using a fixed dose combination of metformin hydrochloride with fluoxetine…
- Trial name
- Metfluo (NCT03051451)
- Testing
- combination metformin hydrochloride/ fluoxetine 500/20 mg, combination metformin hydrochloride/ fluoxetine 1000/20mg
- Where
- Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Obesity-hypoventilation Syndrome, Resting Energy Expenditure
Resting Energy Expenditure in Patients With OHS Treated With Long-term NIV
This study aims to compare, in subjects with obesity-hypoventilation syndrome (OHS) treated by long-term non-invasive ventilation (NIV), resting energy expenditure (REE) in spontaneous breathing and under NIV.
- Conditions
- Obesity-hypoventilation Syndrome, Resting Energy Expenditure, Long-term Non-invasive Ventilation
- Trial name
- NCT04474587
- Testing
- Indirect calorimetry
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Geneva
Overweight, Obesity
Vitamin D and Type 2 Diabetes Risk in UK Adults
This study is exploring the association between vitamin D and Type 2 diabetes risk in normal weight and overweight UK adults.
- Trial name
- NCT04339530
- Testing
- Normal weight and overweight adults
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Liverpool Hope University
Obesity
Testing the Gravitostat in Humans: the Impact of a Weighted Vest in Patients Post Bariatric Surgery on Fat-free Mass Retention and Weight Loss
The mechanisms regulating fat mass homeostasis are incompletely understood although recent animal and human trials would suggest that there is a leptin independent regulatory pathway which may play a role in weight control and…
- Trial name
- NCT04809129
- Testing
- Weighted vest
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Physical Exercise, Bariatric Surgery
Physical Exercise in Postoperative Bariatric Surgery Patients
This study aims to determine the effect of two types of exercise training on body composition, cardiopulmonary function and quality of life in people after undergoing bariatric surgery.
- Conditions
- Physical Exercise, Bariatric Surgery, Morbid Obesity
- Trial name
- NCT04235842
- Testing
- Physical Exercise, High-intensity interval training performed at cycle ergometer.
- Where
- Chile
- Volunteers
- 75 people
- Sponsor
- Universidad Católica del Maule
Physical Inactivity, Obesity, Childhood
Effectiveness of a Telehealth-based Physical Activity Intervention
This study is a 11 week telehealth intervention focusing on increasing physical activity in adolescents who are receiving medical care for obesity. The participants will be randomized into two groups: control and intervention.
- Trial name
- NCT05123235
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Healthy
Effect of Garlic on Inflammatory Mediators
This research will investigate the effect of garlic oil extract when added to daily diet on inflammatory mediators and blood clotting activation.
- Trial name
- NCT00275405
- Testing
- Garlic Oil Macerate
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Obesity, Childhood
Acetaminophen Dosing in Obese Adolescents
Although there are numerous studies investigating the pharmacokinetic properties of intravenous acetaminophen in infants and children with normal weight, there are none in the obese pediatric patient .
- Trial name
- NCT03192566
- Testing
- Tylenol
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Obesity-Related Malignant Neoplasm
A Food Security Intervention for the Prevention of Cancer in Low-income Families
This study is being done to see how produce delivery with or without nutritional education affects what people eat and if it can help improve diet and nutrition in low-income families and their ability to get enough healthy food.
- Trial name
- NCT07039630
- Testing
- Food Assistance Programs, Health Promotion and Education, Questionnaire Administration
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Insulin Resistance, Obesity
Effect of 4 Weeks of Shuttle Run Training on Insulin Sensitivity in Sedentary Men
A number of studies have shown that short duration, high intensity interval training can improve health-related outcomes, such as insulin sensitivity and cardiorespiratory fitness.
- Conditions
- Insulin Resistance, Obesity, Metabolic Syndrome
- Trial name
- NCT01962857
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Diabetes Mellitus, Type 2, Diabetic Nephropathy
Molecular and Clinical Profile of Diabetes Mellitus and Its Complications
Background: Family and twin studies have suggested that genetic factors influence approximately 50 percent of a person's susceptibility to type 2 diabetes.
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Nephropathy, Obesity
- Trial name
- NCT01105858
- Where
- United States
- Volunteers
- 2,310 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pregnancy Complications, Obesity, Maternal
Innovations in Placental Metabolism and Association With Antioxidants and Nutrients in Diabetes and Gestational Obesity
This research project aims to investigate, in an innovative way, the molecular pathophysiology of gestational complications induced by maternal obesity and gestational diabetes mellitus (GDM).
- Conditions
- Pregnancy Complications, Obesity, Maternal, Diabetes Mel Gestational - in Pregnancy
- Trial name
- IMPACTING (NCT05174728)
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Atrial Fibrillation, Obesity
Semaglutide to Reduce Atrial Fibrillation Burden
Atrial fibrillation (AF) is the most common arrhythmia worldwide. AF is associated with obesity and the co-morbidities of obesity, including hypertension and obstructive sleep apnea (OSA) which increase left atrial (LA) size and…
- Conditions
- Atrial Fibrillation, Obesity, Overweight
- Trial name
- NCT05209165
- Testing
- Semaglutide
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- San Francisco Veterans Affairs Medical Center
Obesity, Bariatric Surgery
Role and Mechanisms of Obesity Surgery
The purpose of this study is to examine how physical activity and lifestyle factors influence postoperative recovery and postoperative complications after bariatric surgery.
- Conditions
- Obesity, Bariatric Surgery, Physical Activity, Post-operative Complications
- Trial name
- RAMOSPHYSSURG (NCT01998815)
- Testing
- Laparoscopic Roux-en-Y gastric bypass surgery
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Göteborg University
Intra-Abdominal Fat
The Healthy Diet and Lifestyle Study II
Intermittent energy restriction (IER) may have important advantages over daily energy restriction (DER) in producing sustained weight loss and reducing cancer risk.
- Trial name
- (HDLS2) (NCT05132686)
- Testing
- IER+MED, MED/DER
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Hawaii