Clinical trials: Obesity &Amp;Amp; Overweight
Obesity &Amp; Overweight
Prehabilitation Strategies for Patients Undergoing Laparoscopic Sleeve Gastrectomy
This study aims to evaluate the effectiveness of prehabilitation strategies in patients undergoing laparoscopic sleeve gastrectomy (LSG).
- Trial name
- NCT07076901
- Testing
- Psychological Support, Supervised Exercise Program, Lifestyle and Dietary Modification
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Hospital of Hebei Medical University
Obesity &Amp; Overweight
The Impact of Probiotics on Bariatric Treatment Outcomes
The planned study aims to assess whether probiotics improve the quality of life in patients during the early postoperative period following sleeve gastrectomy, and whether they influence the absorption of micro- and…
- Trial name
- PROBE (NCT07258732)
- Testing
- Probiotic, Diet
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Attention Deficit Hyperactivity Disorder (ADHD), Obesity (Body Mass Index &Amp;Amp;gt;30 kg/m2)
PHArmaCokinetics of methYLphenidate in Adult Patients With Attention-Deficit /Hyperactivity Disorder
PHACYLOB PHArmaCokinetics of methYLphenidate in adult patients with Attention-Deficit Hyperactivity Disorder (ADHD) : comparison between patients with and without OBesity.
- Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Obesity (Body Mass Index &Amp;Amp;gt;30 kg/m2), Methylphenidate, Obesity &Amp; Overweight
- Trial name
- PHACYLOB (NCT07121621)
- Testing
- PHArmacoKinetics of methYLphenidate in adult patients with ADHD: comparison between patients with and without OBesity.
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Tours
Binge Eating Disorder Associated With Obesity, Binge Eating Disorder
Behavioral Therapy and GLP-1 Analogue Effects on Binge Eating, Weight, and Coping in Obesity
This study is a clinical, longitudinal, non-randomized, prospective observational study that seeks to compare the treatment effects and safety of using GLP-1 analogues versus not using appetite suppressants during a lifestyle…
- Conditions
- Binge Eating Disorder Associated With Obesity, Binge Eating Disorder, Eating Disorder Binge, Eating Disorders
- Trial name
- BETTER-GLP1 (NCT07042672)
- Testing
- GLP-1, CBTe Group Therapy
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Haukeland University Hospital
Obesity &Amp; Overweight
Study to Evaluate the Efficacy and Safety of IN-B00009 Injection in Adults With Obesity or Overweight Without Diabetes Mellitus
This Phase 3 study is designed to evaluate the efficacy and safety of IN-B00009 injection in adults with obesity or overweight without diabetes mellitus
- Trial name
- NCT07192263
- Testing
- IN-B00009
- Volunteers
- 300 people
- Sponsor
- HK inno.N Corporation
Obesity &Amp;Amp; Overweight, Bariatric Surgery
EFFECTS OF SUPERVISED PHYSICAL EXERCISE AFTER BARIATRIC SURGERY ON MUSCLE MASS AND BONE DENSITY (OBEFIT STUDY)
CLINICAL TRIAL ON THE EFFECT OF SUPERVISED PHYSICAL EXERCISE AFTER BARIATRIC SURGERY ON MUSCLE MASS AND BONE DENSITY (OBEFIT STUDY)
- Conditions
- Obesity &Amp;Amp; Overweight, Bariatric Surgery, Physical Exercise
- Trial name
- BARIATRIC (NCT07324447)
- Testing
- physical exercise programme
- Where
- 2 sites in Spain
- Volunteers
- 54 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Obesity &Amp;Amp;Amp; Overweight, Environmental Exposure
Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity
The goal of this study is to examine the relationship in individuals with overweight/obesity and endocrine disrupting chemical (EDC) exposure through a two-armed, randomized clinical trial.
- Conditions
- Obesity &Amp;Amp;Amp; Overweight, Environmental Exposure, Overweight (BMI > 25)
- Trial name
- LiveWell (NCT07560579)
- Testing
- Educational curriculum, Weight loss Application, Urinary EDC metabolite testing
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Million Marker Wellness, Inc.
Mechanical Ventilation, Extubation
Spontaneous Breathing Trials Using Pressure Support or T-Piece in Overweight and Obese Patients
This study aims to find out which method of spontaneous breathing trial (SBT) better helps overweight and obese ICU patients prepare for extubation, which is the removal of the breathing tube.
- Conditions
- Mechanical Ventilation, Extubation, Obesity &Amp; Overweight, Respiratory Failure
- Trial name
- NCT07114289
- Testing
- Spontaneous breathing trial using pressure support ventilation, Spontaneous breathing trial using T-Piece
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Medical University Hospital
Diabete Mellitus, Cardiovascular Disease Risk Factor
The Mauritius and Rodrigues Non-Communicable Disease (NCD) Study
Mauritius is located in the southern Indian Ocean with a population of 1.3 million in 2023. Mauritius is a multiethnic nation with 68% South Asian, 27% African (Creole), 3% Chinese and 2% Franco Mauritians.
- Conditions
- Diabete Mellitus, Cardiovascular Disease Risk Factor, Ischemic Cardiovascular Disease, Hypertension
- Trial name
- NCT07048717
- Where
- Mauritius
- Volunteers
- 39,082 people, healthy volunteers welcome
- Sponsor
- Umeå University
Obesity &Amp; Overweight
A Drug Drug Interaction Study to Evaluate the Effect of VCT220 on the Pharmacokinetics of Repaglinide, Rosuvastatin, and Digoxin in Healthy, Overweight, and Obese Subjects
This is a single-center, open-label, single-arm, fixed-sequence Phase I study in healthy, overweight, and obese subjects. The primary objective is to evaluate the effect of orally administered VCT220 tablets on the…
- Trial name
- NCT07065058
- Testing
- Drug: VCT220, Repaglinide, Rosuvastatin, and Digoxin
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vincentage Pharma Co., Ltd
Obesity &Amp; Overweight, Peri Implantitis
The Role of Obesity in Peri-Implant Health(ROPIPH)
This clinical study aims to evaluate the influence of obesity on peri-implant health. Both clinical parameters and biochemical markers in peri-implant crevicular fluid(PICF) will be assessed.
- Conditions
- Obesity &Amp; Overweight, Peri Implantitis, Dental Implant
- Trial name
- ROPIPH (NCT07183163)
- Testing
- Clinical and biochemical assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mine Keskin
Gestatiaonl Diabetes Mellitus, Insulin Resistance
Impact of Gestational Diabetes on Childhood Obesity
In this study, we aimed to investigate the relationship between obesity, glucose intolerance (insulin resistance), dyslipidemia and diabetes in children aged 5-12 born to mothers with Gestational Diabetes Mellitus (GDM) in…
- Conditions
- Gestatiaonl Diabetes Mellitus, Insulin Resistance, Dyslipaemia, Obesity &Amp; Overweight
- Trial name
- NCT07069296
- Testing
- blood samples were collected from participants, blood samples
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Obesity &Amp; Overweight
Effects of Grape Consumption on the Immune-Gut Axis in Obesity
This study is investigating the benefits of whole freeze-dried grape powder consumption on the immune-gut axis in adults with obesity.
- Trial name
- NCT07231484
- Testing
- Freeze-dried grape powder
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Missouri-Columbia
Obesity &Amp; Overweight, Obesity Type 2 Diabetes Mellitus
Fat Around Heart Arteries as a Measure of Inflammation in Patients With Glycometabolic Disease
In this study, the objective is to investigate inflammation in the arteries of the heart. A heart CT scan (CCTA) will be used to measure inflammation by assessing the fat tissue surrounding the arteries of the heart.
- Conditions
- Obesity &Amp; Overweight, Obesity Type 2 Diabetes Mellitus, Type 2 Diabetes (T2DM), Prediabetes
- Trial name
- PCAT-GMD (NCT07144670)
- Where
- Denmark
- Volunteers
- 747 people
- Sponsor
- Odense University Hospital
Hypertension (HTN), Obesity &Amp; Overweight
Mediterranean-DASH Intervention for Neurodegenerative Delay and High-Intensity Interval Training in Adults With Hypertension
This pilot study examines whether a 4-week diet and exercise intervention can improve blood pressure, heart health, and sleep in physically inactive individuals with high blood pressure and overweight or obesity.
- Conditions
- Hypertension (HTN), Obesity &Amp; Overweight, Sedentary
- Trial name
- MIND HIIT (NCT07130539)
- Testing
- MIND HIIT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Texas Woman's University
The Study Focused on the Vascular Effects of Semaglutide in Both Diabetic and Non-diabetic Patients, Obesity &Amp; Overweight
Coronary Flow Reserve Changes After Semaglutide Treatment
The goal of this observational study is to learn about the effects of semaglutide to coronary artery flow in diabetic and non-diabetic patients.
- Trial name
- NCT07190144
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Ekrem Bilal Karaayvaz
Cognitive Impairment, Diet Interventions
The Resistant Starch Intervention for Cognitive Enhancement
The investigation will explore the potential effects of resistant starch The Resistant Starch Intervention for Cognitive Enhancement study aimed to evaluate the effect of high-resistant starch diet intervention in slowing…
- Conditions
- Cognitive Impairment, Diet Interventions, Cognitive Decline, Genetic Risk Factors
- Trial name
- NCT07152483
- Testing
- High resistant starch staple foods, Regular starch staple foods
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Obesity &Amp; Overweight, Hypertension
A Prospective Randomnised Controlled Trial Comparing Overall Patient Compliance in a Bariatric Surgical Pathway Using the Standard Versus a More Intensified and Interactive Version of the "Get Ready" Smartphone Application.
The aim of this study is to assess the impact of a newly intensified digital platform following bariatric surgery. This will be measured using several questionnaires.
- Conditions
- Obesity &Amp; Overweight, Hypertension, Obstructive Sleep Apnea (OSAS), Diabetes Mellitus ( Type 1 and Type 2)
- Trial name
- NCT07297342
- Testing
- GetReady application, Intensified GetReady application
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Sint Dimpna Ziekenhuis Geel
Obesity &Amp; Overweight
Phase 1/2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effect on Body Weight of RN3161 as Monotherapy and in Combination With Tirzepatide in Adults With Overweight and Obesity
Study to assess the safety, pharmacokinetics (the amount of study drug or any of its breakdown products in your body) and pharmacodynamics (how the study drug affects your body) of RN3161 alone (healthy volunteers) and RN3161…
- Trial name
- NCT07245771
- Testing
- RN3161, Tirzepatide
- Where
- Australia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ikaria Bioscience Pty Ltd
Hypertension, Hyperglycemia
Targeting Metabolic Syndrome From the Emergency Department Through Mixed-Methods: Pilot Trial
The objective of this study is to pilot a multifaceted, optimized intervention for metabolic syndrome (MetS) in emergency department patients to establish feasibility.
- Conditions
- Hypertension, Hyperglycemia, Dyslipidemia, Metabolic Syndrome
- Trial name
- METS (NCT07119658)
- Testing
- Composite intervention to address MetS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University