Clinical trials: Obesity (Disorder)
Obesity, Overweight
Effectiveness of Online Visit Compared With In-person Clinic Visit on Weight Loss
Online visit and online counseling via telemedicine technology is a new service for obese people who wish to lose weight but because of their active lifestyle and time limitation cannot come to clinic.
- Trial name
- NCT03171961
- Testing
- online visit group, Clinic visit group, self-directed group
- Where
- 2 sites in Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Novindiet Clinic
Non-alcoholic Fatty Liver Disease, Obesity
Magnetic Resonance Imaging (MRI) Fat Quantification of the Liver
Fatty liver in the obese is a common finding; some cases develop steato-hepatosis which in the long-term can lead to liver cirrhosis.
- Trial name
- NCT02682173
- Testing
- MR Abdomen
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- University Hospital, Basel, Switzerland
Obesity
AVocAdo Extract to Improve gLycemia in Individuals With Obesity (AVAIL)
This two-arm, double blind, randomized clinical trial will compare the effect of an avocado extract, compared to placebo, on cardiometabolic outcomes in adults with obesity.
- Trial name
- NCT04763473
- Testing
- Avocado extract
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Abdominoplasty Surgery
Correlation Between Intra-abdominal Pressure and Diaphragmatic Mobility in Women Submitted to Abdominoplasty After Bariatric Surgery
Background: Plication of the rectus abdominis muscles leads to an increase in intra-abdominal pressure (IAP), which may negatively impact the respiratory system due to its effects on diaphragmatic mobility (DM).
- Trial name
- NCT06648694
- Testing
- Abdominoplasty surgery, Abdominoplasty
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Compensated Cirrhosis, Obesity
Effects of Weight Loss on Portal Pressure in Patients With Overweight/Obesity and Cirrhosis
Overweight/obesity is increasing both in the general population and in patients with cirrhosis. In compensated patients with cirrhosis increased BMI is a risk factor for clinical decompensation independent of liver function and…
- Trial name
- SPORTDIET (NCT01409356)
- Testing
- Diet + exercise
- Where
- 6 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Clinic of Barcelona
Virtual Reality, Surgical Fear Scale
Effect of a Single Immersive Virtual Reality Session on Preoperative Surgical Fear and State Anxiety
To determine whether a single 20-minute immersive VR nature session delivered in the immediate preoperative period reduces surgical fear and state anxiety in patients scheduled for bariatric surgery.
- Conditions
- Virtual Reality, Surgical Fear Scale, Anxiety
- Trial name
- NCT07774156
- Testing
- Experimental Group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Firat University
Obesity
Effectiveness of Differing Levels of Support for Family Mealtimes on Obesity Prevention Among Head Start Preschools
Socioeconomic disparities in early childhood place low-income children at 1.5 to 2 times higher risk for obesity compared to middle- to upper-income children.
- Trial name
- SimplyDinner (NCT02487251)
- Testing
- Mealtime Supports, Usual Exposure
- Where
- 4 sites in United States
- Volunteers
- 810 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Obesity
Japanese Study of Rimonabant in Obese Patients With Dyslipidemia (VENUS)
The primary objective of this study is to assess the efficacy of SR141716 compared to placebo on body weight and triglycerides changes over a period of 52 weeks.
- Trial name
- NCT00434096
- Testing
- rimonabant (SR141716)
- Where
- Japan
- Volunteers
- 915 people
- Sponsor
- Sanofi
Overweight and Obesity, Type2 Diabetes
A Phase 1 Study of DD01 in Overweight/Obese Subjects With T2DM and NAFLD
This is a Phase 1, first in human (FiH), randomized, double-blind, placebo-controlled, single ascending dose (SAD) and multiple ascending dose (MAD) study to investigate the safety, tolerability, PK and PD of DD01 administered by…
- Conditions
- Overweight and Obesity, Type2 Diabetes, NAFLD
- Trial name
- NCT04812262
- Testing
- DD01
- Where
- 4 sites in United States, Puerto Rico
- Volunteers
- 255 people
- Sponsor
- Neuraly, Inc.
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Obesity, Overweight
Comparing of Long Bout and Short Bouts of Similar Volume of Walking in Obese on Weight Loss During a Weight Loss Program
The purpose of this present study is to determine if a daily walking program of 50 continuous minutes (long bout) or two 25-minute bouts (short bouts) in similar volume on body weight, abdominal fat mass deposition and…
- Trial name
- NCT02387827
- Testing
- Diet+ short term versus long -term physical activity
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Novindiet Clinic
Obesity, Eating Disorders
Psychosocial Issues and Bariatric Surgery
Bariatric surgery is associated with long-term weight loss, as well as short-term improvements in obesity-related medical comorbidities.
- Conditions
- Obesity, Eating Disorders, Bariatric Surgery Candidate, Depressive Disorder
- Trial name
- LABS3 (NCT02495142)
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Neuropsychiatric Research Institute, Fargo, North Dakota
Obesity (Disorder), Child Obesity
Pharmacological Treatment - An Overview of Its Role in Managing Childhood Obesity
The aim of the study is to examine the effects of pharmacological treatment for obesity on BMI trajectories and metabolic markers among patients in routine clinical care. A retrospective observational study.
- Trial name
- NCT07304141
- Testing
- Liraglutide 3 mg (Saxenda)
- Where
- Sweden
- Volunteers
- 128 people
- Sponsor
- Göteborg University
Insulin Resistance, Healthy
Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in Obesity
The purpose of this study is to better understand the contribution of sympathetic vasoconstriction to impaired insulin-mediated vasodilation and subsequently insulin-mediated glucose uptake.
- Conditions
- Insulin Resistance, Healthy, Obesity
- Trial name
- NCT03318094
- Testing
- Phentolamine, Saline, Sodium Nitroprusside
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Postprandial Hyperglycemia
Comparison of Different Types of Resistant Starch
This study is to determine whether different types of resistant starch have different effects on blood glucose in healthy adults.
- Trial name
- NCT00930956
- Testing
- Resistant Starch
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Wound Dehiscence
External Negative Pressure Dressing System vs. Traditional Wound Dressing for Cesarean Section Incision in Obese Women.
Obesity is associated with increased cesarean section delivery rates and surgical site infections with associated increased post-operative morbidity, post-operative pain and length of hospital stay.
- Trial name
- NCT04434820
- Testing
- External negative pressure dressing system (Yuwell 7E-A portable suction unit)
- Where
- Egypt
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Obesity, Atherosclerosis
Observational Study of Early Metabolic and Vascular Changes in Obesity
To work against the increasing burden of obesity, the STYJOBS / EDECTA (STYrian Juvenile OBesity Study / Early DetECtion of Atherosclerosis) project was started at the Medical University of Graz in 2003.
- Conditions
- Obesity, Atherosclerosis, Inflammation, Adiponectin Deficiency
- Trial name
- STYJOBS (NCT00482924)
- Testing
- Lifestyle intervention
- Where
- Austria
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Obesity
The Therapeutic Effects of Topiramate and Metformin on Second Generation Antipsychotics-induced Obesity
The primary aim of the study is to investigate the efficacy of metformin and topiramate on second-generation antipsychotic-induced obesity. The secondary domain we look at is the adverse effects of both drugs.
- Trial name
- NCT01384279
- Testing
- metformin, topiramate
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Beitou Armed Forces Hospital, Taipei, Taiwan
Morbid Obesity
Sleeve Gastrectomy: Outcome, Morbidity and Mortality. A Multicentric Retrospective Trial
Laparoscopic sleeve gastrectomy (LSG) is currently the most frequent primary bariatric procedure performed worldwide. LSG is a safe and effective technique in terms of excess weight loss and it is, moreover, a powerful metabolic…
- Trial name
- PSICHE (NCT04643262)
- Testing
- Sleeve Gastrectomy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Health Impairment, Pain
High School Football and Adult Health
The primary aim of the study is to determine the effect of playing high school football on self-rated health in late adulthood. This is an observational study that will use data from the Wisconsin Longitudinal Study, a…
- Conditions
- Health Impairment, Pain, Obesity
- Trial name
- NCT03914573
- Where
- 2 sites in United States
- Volunteers
- 3,355 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania