Clinical trials: Obesity /Overweight
Obesity &Amp; Overweight, General Anesthetic
Postoperative Opioid Consumption in Gastric Sleeve Surgery
The study aimed to compare balanced anesthesia protocols using only opioids as analgesics during induction in gastric sleeve surgery with protocols using opioids and ketamine together in terms of anesthesia management, opioid…
- Conditions
- Obesity &Amp; Overweight, General Anesthetic, Ketamine
- Trial name
- POCiGSS (NCT07135154)
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Balikesir University
Obesity
Weight Loss With Exenatide Treatment
The investigators are conducting a study that will investigate the possible mechanisms of weight loss associated with exenatide treatment and the metabolic characteristics of high responders (i.e.
- Trial name
- NCT01590433
- Testing
- Exenatide, Dietary counseling
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Jody Dushay
Obesity, Prediabetic State
Effects of Melatonin Supplementation on Renal Physiology in a Habitual Sleep Restricted Population.
In a 6 week pilot study, 20 individuals with habitual sleep restriction will all be asked to extend their nightly sleep by 1 hour, and will then be randomized 1:1 to nightly controlled-release oral melatonin (2mg) or placebo.
- Trial name
- MAST (NCT02631148)
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obesity
Increasing Uptake of Behavioral Weight Loss Programs Among Primary Care Patients
This pilot trial will test feasibility and acceptability of a primary care-based intervention that aims to increase the portion of patients who enter evidence-based behavioral weight loss treatment.
- Trial name
- NCT02708121
- Testing
- Motivational Intervention, Comparator Intervention
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Florida
Overweight, Obesity
The Effects of Leucine on Body Weight
Protein-rich diets appear to show some benefits in promoting weight loss. It is thought that increased intake of leucine may account for some of this effect.
- Trial name
- NCT00683826
- Testing
- L-Leucine 8gr, Liquid meal, L-Leucine 4g
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Columbia University
Metabolism and Nutrition Disorder, Obesity
Effect of Liraglutide on Body Weight in Overweight or Obese Subjects With Type 2 Diabetes: SCALE™ - Diabetes
This trial is conducted in Africa, Asia, Europe and the United States of America (USA). The aim of this trial is to investigate the potential of liraglutide to induce and maintain weight loss in overweight or obese subjects with…
- Trial name
- NCT01272232
- Testing
- liraglutide
- Where
- 161 sites in United States, France and 11 more
- Volunteers
- 846 people
- Sponsor
- Novo Nordisk A/S
Non-alcoholic Fatty Liver Disease
Obesity and Nonalcoholic Fatty Liver Disease
The primary goal of this study is to provide a better understanding of: 1) the pathogenesis and pathophysiology of non-alcoholic fatty liver disease (NAFLD) in obese subjects, and 2) the effect of marked weight loss on the…
- Trial name
- NCT00262964
- Testing
- Niacin, fenofibrate
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Washington University School of Medicine
Childhood Obesity
Family Connections: Cultural Adaptation and Feasibility Testing for Rural Latino Communities
There are marked ethnic and rural-urban disparities in the prevalence of childhood obesity (CO). Among Latino/Hispanic children, CO is almost 60% higher than that of non- Latino/Hispanic Whites, and among children in rural areas…
- Trial name
- NCT04731506
- Testing
- Family Connections
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Nebraska
Arthritis, Cancer
MoveStrong at Home: A Feasibility Study of a Model for Remote Delivery of Functional Strength and Balance Training Combined With Nutrition Education for Older Pre-frail Adults.
Sufficient muscle strength helps to get out of a chair and can prevent falls. Up to 30% of older adults experience age-related loss of muscle strength, which can lead to frailty and health instability.
- Conditions
- Arthritis, Cancer, Cardiovascular Diseases, Chronic Lung Disease
- Trial name
- NCT04663685
- Testing
- Exercise program, Nutrition education
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Waterloo
Prader-Willi Syndrome
A Study of Diazoxide Choline in Patients With Prader-Willi Syndrome
The purpose of this is study is to evaluate the effects of DCCR (diazoxide choline controlled release tablets) in children and adults with Prader-Willi syndrome.
- Trial name
- NCT03440814
- Testing
- DCCR
- Where
- 29 sites in United States, United Kingdom
- Volunteers
- 127 people
- Sponsor
- Soleno Therapeutics, Inc.
Overweight, Obesity
Novel and Scalable Internet Supplemented Weight Loss Treatment in Primary Care
Motivational interviewing and nutritional counseling for weight loss in primary care.
- Trial name
- NCT02578199
- Testing
- motivational interviewing and nutrition
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Yale University
Obesity, Liver Cirrhosis
Endoscopic Intragastric Balloon Placement for Weight Loss in Liver Transplant Waitlist Candidates
The purpose of this study is to determine whether the Orbera Intragastric Balloon is a safe and effective means for weight loss and improved metabolic disease in patients with cirrhosis requiring liver transplantation.
- Trial name
- NCT02556138
- Testing
- ORBERA Intragastric Balloon
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Mayo Clinic
Obesity
A First-Time-in-Human Study to Assess the Safety and Tolerability of PP 1420 in Healthy Subjects
When humans eat, the bowels naturally secrete chemicals into the bloodstream which make people feel full and which stop eating. One of these chemicals is known as "Pancreatic Polypeptide" (PP).
- Trial name
- NCT01052493
- Testing
- PP 1420
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Mental Illness, Obesity
Using MOVE! With Seriously Mentally Ill Veterans
This study involves a controlled trial of an optimized version of a weight management and physical activity psycho-educational intervention (called MOVE!) with 200 obese and overweight veterans with serious mental illness.
- Trial name
- NCT00323193
- Testing
- MOVE!
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Obesity; Overweight
Effect of GLP-1 Analogue ROSE-010 on Appetite in Overweight and Obese Subjects
The primary objective of this study is to assess the efficacy of ROSE-010 on food intake in female subjects with overweight and obesity.
- Trial name
- NCT06621017
- Testing
- ROSE-010 99 mcg, ROSE-010 150 mcg
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rose Pharma Inc
Blood Pressure
A Study of VI-0521 on Ambulatory Blood Pressure (ABPM) in Overweight or Obese Subjects
The study is being conducted to evaluate the effect of VI-0521 (Qsymia®) on blood pressure as measured by 24-hour ambulatory blood pressure monitoring, compared to both placebo and an active control (phentermine 30 mg).
- Trial name
- NCT05215418
- Testing
- VI-0521, Phentermine
- Where
- 28 sites in United States
- Volunteers
- 565 people
- Sponsor
- VIVUS LLC
Overweight and Obesity
Episodic Future Thinking and Weight-Loss
Family-based treatments (FBT) for obesity have been shown to be effective in achieving significant weight reductionin overweight or obese children and parents [Altman \& Wilfley, 2015].
- Trial name
- NCT03731325
- Testing
- Episodic Future Thinking Group
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- State University of New York at Buffalo
Fatty Liver, Non-Alcoholic Steatohepatitis
A Clinical Trial to Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients With NASH
This is a multicenter, Phase IIb, randomized, double blind, placebo-controlled study designed to evaluate the efficacy and safety of two Aramchol doses in subjects that are 18 to 75 years of age, with Non-Alcoholic…
- Conditions
- Fatty Liver, Non-Alcoholic Steatohepatitis, Liver Diseases, Liver Fibroses
- Trial name
- Aramchol_005 (NCT02279524)
- Testing
- Aramchol
- Where
- 78 sites in United States, Chile and 9 more
- Volunteers
- 247 people
- Sponsor
- Galmed Research and Development, Ltd.
Overweight, Obese
Low Level Laser Treatment (LLLT) and Lorcaserin for Weight Management
Currently in the United States about 97 million adults are considered obese, accounting for about 33% of the American adult population (compared to 22.9% in 1988).
- Trial name
- NCT02129608
- Testing
- LLLT, Lorcaserin
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Postpartum Weight Retention, Obesity
Feasibility of Meal Delivery Postpartum
This study is being done to assess the feasibility and acceptability of a meal delivery intervention among low-income postpartum women with obesity.
- Trial name
- NCT05579990
- Testing
- Meal Delivery
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Alabama at Birmingham
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