Clinical trials: Obesity Overweight
Obese, Overweight
Effects of Food Form on Cephalic Phase Responses
This study has two main aims: 1) To determine if ingestion of solid or beverage food forms will change appetite hormone responses, and 2) To determine whether "learning" (defined as 2 week daily consumption) about the metabolic…
- Trial name
- NCT01550133
- Testing
- Learned: Non-nutritive beverage to Non-nutritive beverage, Learned: Nutritive solid to Nutritive solid, Learned: Nutritive beverage to Nutritive beverage
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Purdue University
Obesity
Effects of GLP-1 RAs on Weight and Metabolic Indicators in Obese Patients
This studay evaluates the effect of the glucagon-like peptide-1 (GLP-1) receptor agonist,including Liraglutide,Exenatide and Exenatide Microspheres for Injection,in the treatment of subjects who are overweight or obese.
- Trial name
- NCT03671733
- Testing
- Liraglutide, Exenatide, Exenatide Microspheres for Injection
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xiangya Hospital of Central South University
Heart Failure
Reverse HFpEF: Ketogenic Reversal of Heart Failure With Preserved Ejection Fraction Study
This protocol is a prospective pilot study utilizing the intervention of a medically supervised, registered nurse and registered diabetes educator coached low-carbohydrate, ketogenic diet to examine the impact it has as a…
- Trial name
- NCT04942548
- Testing
- Ketogenic Diet
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- National Jewish Health
Diabetes Mellitus, Type 2 Diabetes Mellitus
Qatar Universal Diabetes Outcomes (QUDOS) Study
QUDOS is a cross-sectional population study aiming to answer key questions about diabetes and its complications in Qatar as well as identify factors associated with the development and progression of diabetes complications.
- Trial name
- QUDOS (NCT02660476)
- Where
- Qatar
- Volunteers
- 475 people
- Sponsor
- Weill Cornell Medical College in Qatar
Obesity, Insulin Resistance
Mitochondrial Function in Pediatric Obesity
The prevalence of pediatric obesity is increasing at an unprecedented rate. Obese children are at risk for the development of insulin resistance, relative insulin deficiency and type 2 diabetes mellitus.
- Trial name
- NCT00577174
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obesity, Heart Failure With Normal Ejection Fraction
Unsaturated Fatty Acids to Improve Cardiorespiratory Fitness in Obesity and HFpEF
This study is designed to evaluate the effects of a diet rich in unsaturated fatty acids (UFA)-also known as 'healthy fats'-in patients with obesity and heart failure with preserved ejection fraction (HFpEF) on dietary…
- Trial name
- UFA-Preserved2 (NCT03966755)
- Testing
- UFA dietary recommendations
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Virginia Commonwealth University
Obesity
Testing Product Messages in Colombia
Purpose: To better understand the impact of different front-of-package labels (FOPLs) on consumer purchasing intentions and ability to identify unhealthy foods.
- Trial name
- NCT05783726
- Testing
- Control, Nutriscore Label, Adapted Peruvian Nutrient Label
- Where
- United States
- Volunteers
- 8,086 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Gestational Diabetes Mellitus
Pre-pregnancy Lifestyle Intervention to Prevent the Recurrence of Gestational Diabetes in Overweight and Obese Women
The overall purpose of this study is to determine the efficacy of a pre-pregnancy lifestyle intervention to reduce the recurrence of gestational diabetes mellitus in multiethnic women with overweight or obesity.
- Trial name
- NCT02763150
- Testing
- Lifestyle intervention, Health Promotion
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Obesity
Macronutrient Relations and Weight Loss in Obese Subjects
The burden of overweight and obesity has dramatically increased during the last decades. High carbohydrate intake, particularly refined carbohydrates, probably increase the risk of obesity, type 2 diabetes, and metabolic…
- Trial name
- NCT00868387
- Testing
- energy-restricted, CHO-restricted diet, energy-restricted, CHO-rich diet
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Obesity, Overweight
Koa Family Study--A Community-Based Intervention to Improve Health and Well-Being
Wholehearted living touches every aspect of life, from eating nourishing foods, to enjoying enough physical activity, to cultivating relationships that support healthy choices, to joining with neighbors to stand up for positive…
- Conditions
- Obesity, Overweight, Diet, Healthy, Social Interaction
- Trial name
- KFS (NCT04662593)
- Testing
- Whole Health Program
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Obesity
Effect of Obesity on Immune Response to Pneumovax 23
Pneumococcal infections are a leading cause of adult and childhood hospitalization and death. It has been shown that obese individuals are at higher risk for this bacterial infection.
- Trial name
- ROVE (NCT02471014)
- Testing
- Pneumovax 23, Blood tests, Questionnaires
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Florida
Obesity
LEAP2 Kinetics in Healthy Individuals
The study aims to investigate the kinetics of the naturally occurring peptide liver-enriched antimicrobial peptide 2 (LEAP-2) in healthy volunteers.
- Trial name
- NCT04897984
- Testing
- Liver-enriched antimicrobial peptide 2
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Invitro Fertilization
The Impact of Body Weight on Reproductive Outcomes in Poor Ovarian Responders in ICSI Cycles
Induction of ovulation cycle: 1. Gonadotrophines is started on day 2 with HMG(merional, IBSA) ,until the day of HCG administration(choriomon,IBSA10000IU) with starting dose 300 to 450iu. 2.
- Trial name
- NCT03457233
- Testing
- Gonadotropins, GNRH antagonist, Human chorionic gonadotropin Chorimon
- Where
- Egypt
- Volunteers
- 185 people
- Sponsor
- Cairo University
Diabetes, Fatty Liver
Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women
Background: Vitamin E is an antioxidant that reduces the damaging effects of oxygen in the body. Most American men (90%) and women (96%) do not get enough vitamin E from their diets; however, the amount of vitamin E needed by the…
- Conditions
- Diabetes, Fatty Liver, Obesity, Healthy Volunteers
- Trial name
- NCT00862433
- Testing
- Alpha tocopherol, Vitamin E, Vitamin C
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Morbid, Weight Gain
Transit Bipartition After Sleeve Gastrectomy
Retrospective analysis of 100 morbidly obese patients who underwent a transit bipartition (TB) procedure ("Single Anastomosis Sleeve Ileal bypass") for inadequate weight loss or weight recidivism after a previous sleeve…
- Conditions
- Obesity, Morbid, Weight Gain, Bariatric Surgery Candidate
- Trial name
- TB-LSG (NCT04782648)
- Testing
- transit bipartition
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Ruhr University of Bochum
Obesity, Genetic Disorder
Brain-Derived Neurotrophic Factor in Obesity and Brain Function
Background: Prader-Willi syndrome (PWS) and MC4R genetic mutations are two conditions that can cause problems with appetite regulation. People with PWS often have behavior and thinking problems.
- Conditions
- Obesity, Genetic Disorder, Mental Retardation, Developmental Delay
- Trial name
- NCT01517048
- Where
- 2 sites in United States, Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pregnancy in Obesity, Gestational Weight Gain
Optimizing GWG in Obese Pregnant Women: A Nationwide Real-World Study Using the U.S. Natality Cohort
The goal of this observational study is to find out which amount of weight gain during pregnancy is safest for women with obesity and their babies.
- Trial name
- GWG (NCT07796815)
- Testing
- Gestational Weight Gain
- Where
- United States
- Volunteers
- 1,600,000 people
- Sponsor
- Shanghai First Maternal and Infant Health Hospital affiliated to Tongji University Medical School
Obesity
Effect of LY3437943 Versus Placebo in Participants Who Have Obesity or Are Overweight
Phase 2, multicenter, randomized, double-blind, placebo-controlled study evaluating once-weekly subcutaneous retatrutide (LY3437943) at multiple maintenance dose levels versus placebo in adults with obesity or overweight with…
- Trial name
- GZBF (NCT07467447)
- Testing
- Retatrutide (LY3437943), Standardized diet and physical activity counseling throughout the study.
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Hudson Biotech
Gestational Diabetes, Type2 Diabetes
The Belgian Diabetes in Pregnancy Follow-up Study
Gestational diabetes (GDM) is a form of diabetes that develops during pregnancy. GDM is associated with increased risks for pregnancy complications such as macrosomia s and preterm delivery.
- Conditions
- Gestational Diabetes, Type2 Diabetes, Obesity
- Trial name
- BEDIP-FUS (NCT04429958)
- Testing
- GDM
- Where
- 5 sites in Belgium
- Volunteers
- 630 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity / Overweight
Effects of Tirzepatide on Gut Microbiota and Gastrointestinal Function After Drug Withdrawal in Obese Patients
This is an observational cohort study. The primary objective is to analyze the dynamic changes in gut microbiota and metabolic profiles in obese patients treated with Tirzepatide.
- Trial name
- NCT07847515
- Testing
- Tirzepatide
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.