Clinical trials: Obesity Overweight
Obesity
The Effect and the Pharmacogenomics Study of Liraglutide in Obese Patients
This studay evaluates the effect of liraglutide in the treatment of obese patients ande the influence of genetic factors on the curative effect.Half of participants will receive Liraglutide alone,while the other half who can not…
- Trial name
- NCT04839237
- Testing
- Liraglutide, Liraglutide;metformin
- Where
- China
- Sponsor
- Xiangya Hospital of Central South University
Obesity
Pleasure for Food and Endocannabinoids in Obesity
Disturbances in hedonic and motivational processes play a major role in the pathophysiology of obesity. To date, experimental approaches for the study of emotional and motivational processing rely on subjective assessment scales.
- Trial name
- PLOBEC (NCT01985139)
- Testing
- Computer-based tasks, Blood sampling
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Childhood Obesity
Healthy Weight Poster, Multi-site Study
This is a multi-site, cross-sectional study of 3-8 year old children and their parents presenting for a well-child check. The investigators are assessing whether a novel, educational, exam room poster can effectively prompt…
- Trial name
- NCT03128112
- Testing
- Exam room with poster
- Where
- 7 sites in United States
- Volunteers
- 965 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Obesity
Acceptability of Dietary Fibre-based Foods
Obesity is a wide reaching problem in the United Kingdom. The most widely used obesity therapies are based around drugs that reduce dietary fat digestion, and thereby reduce uptake of calories from the diet.
- Trial name
- NCT03477981
- Testing
- Alginate bread
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Obesity
PRebiotic to IMprovE Calcium Absorption
Gastric bypass surgery is a highly effective treatment for obesity, but it has negative effects on skeletal health, due in part to a dramatic decline in intestinal calcium absorption capacity.
- Trial name
- PRIME (NCT03272542)
- Testing
- Prebiotic: soluble corn fiber
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- San Francisco Veterans Affairs Medical Center
Morbid Obesity Requiring Bariatric Surgery
Relationship Between Serum Resistin Levels and Reduction in Visceral Fat in Patients Undergoing Sleeve Gastrectomy Due to Morbid Obesity
This study aims to investigate whether a specific protein in the blood, called resistin, can help doctors predict how much dangerous internal fat a patient will lose following weight loss surgery.
- Trial name
- NCT07564986
- Testing
- Laparoscopic Sleeve Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sercan YUKSEL, MD
Obesity
MGB/OAGB Versus RYGB After Failed Sleeve
Sleeve Gastrectomy is the most performed bariatric procedure worldwide. But a growing number of data documents that some patients have to be surgical revised due to weight regain or gastro-esophageal reflux disease.
- Trial name
- NCT03526783
- Testing
- Roux en Y gastric bypass, Mini/One anastomosis gastric bypass
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Sana Klinikum Offenbach
Childhood Obesity
Healthy Kids Pilot
Up to 30 parent/child dyads will be recruited to participate in an m-Health intervention (delivered over smartphone, iPad/Tablet, or desktop/laptop) to promote healthy behaviors and healthy weight among children and their parents.
- Trial name
- NCT03297554
- Testing
- m-Health Intervention
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Non-Alcoholic Fatty Liver Disease, Non Alcoholic Fatty Liver
Probiotic Lysate (Postbiotic and Metabiotic) Supplementation for Adults NAFLD Patients (DELI_NAFLD Study)
The current study aim was to conduct placebo-controlled randomize clinical trial to assess the short-term efficacy and safety of postbiotics on hepatic fat content as measured by MRI-PDFF and ultrasonography, liver stiffness (LS)…
- Conditions
- Non-Alcoholic Fatty Liver Disease, Non Alcoholic Fatty Liver, Hepatic Steatosis, Fatty Liver
- Trial name
- NCT05804422
- Testing
- Probiotic lysate (postbiotic and metabiotc)
- Where
- 4 sites in Ukraine
- Volunteers
- 39 people
- Sponsor
- Bogomolets National Medical University
Overweight and Obesity
Online Dietary Weight Loss Program for Arab Adults: A Randomized Controlled Trial
This study is testing whether a culturally adapted online dietary and lifestyle program can help Arab adults in Saudi Arabia lose weight and improve their overall health.
- Trial name
- NCT07518875
- Testing
- Online Lifestyle and Dietary Program, Usual Dietary Care
- Where
- Saudi Arabia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Asma Yahya
Obesity and Obesity-related Medical Conditions
Evaluation of a Primary Care Based Lifestyle Medicine Clinic at UAB
This is a randomized quality improvement project (i.e., not a research study) that will test the implementation and effectiveness of a lifestyle medicine clinic at the University of Alabama at Birmingham.
- Trial name
- NCT06989281
- Testing
- FLOW Lifestyle Medicine Clinic
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Alabama at Birmingham
Obesity, Inflammation
Effects of Dietary Fatty Acids on Octadecanoid Production and Biological Actions in Obesity-induced Inflammation
This is a single site, double-blind, randomized, crossover study designed to compare the effects of dietary supplementation with flax oil rich in alpha-linolenic acid (ALA) and fish oil rich in docosahexaenoic acid (DHA) on…
- Trial name
- OXBIO (NCT03583281)
- Testing
- Capsules containing flax oil, Capsules containing DHA-enriched fish oil
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Manitoba
Food Purchases, Eating Behaviour
Fast Food Online Delivery Purchase Behaviour in the Presence and Absence of Price-based Incentives
Consumption of out-of-home (OOH) food is associated with significantly greater energy and less-healthy nutrient (i.e. fats, salt and sugar) intake.
- Trial name
- NCT07368881
- Testing
- Experimental, Control
- Where
- United Kingdom
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Pediatric Obesity
Factors Associated With Changes in Weight-status in Danish School Children With Obesity
Childhood obesity is increasing worldwide and causes a major health concern. Only limited insight exists into the natural history of childhood obesity at children already classified as obese.
- Trial name
- NCT06077266
- Testing
- Change of weight class to normal weight
- Where
- Denmark
- Volunteers
- 467 people
- Sponsor
- University of Aarhus
Overweight (BMI > 25), Obesity & Overweight
Effects of Yerba Mate Supplementation on Metabolic Health, Physical Function, and Cognition in Older Adults With Excess Adiposity
The purpose of this study was to find out whether taking yerba mate, a plant-based supplement, could improve health in adults aged 60 years or older with excess body fat.
- Trial name
- NCT07883031
- Testing
- Yerba Mate
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Alabama
Obesity, Breast Milk Collection
Breastfeeding and Obesity on Offspring Body Composition
The purpose of this study is to explore the effect maternal obesity and breastfeeding play on infant body composition. The investigators hypothesize in the first 6 months of life breast fed offspring from overweight / obese…
- Trial name
- NCT02535637
- Testing
- Exclusively breastfeed
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Obesity, Abdominal
Yoga for Abdominal Obesity
The aim of this randomized trial is to investigate the effects of a 12-week yoga intervention compared to no specific intervention on weight-related outcomes, well-being, and health behaviour in 60 females with abdominal obesity.
- Trial name
- NCT02420145
- Testing
- Yoga
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Universität Duisburg-Essen
Obesity & Overweight
Comparative Effectiveness of Western Pharmacotherapy Versus Integrative Western and Traditional Chinese Medicine for Weight Management in Central Taiwan: A Real-World Cohort Study
Obesity is a major public health issue. While modern Western pharmacotherapies (e.g., GLP-1 receptor agonists) and Traditional Chinese Medicine (TCM) are utilized for weight management, the comparative effectiveness of their…
- Trial name
- NCT07646457
- Where
- Taiwan
- Volunteers
- 296 people
- Sponsor
- National Yang Ming Chiao Tung University
Sleep Apnoea, Obesity & Overweight
Tirzepatide Versus Positive Airway Pressure for the Treatment of Obstructive Sleep Apnoea
When used, continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnea (OSA), a condition that is mainly caused by overweight and obesity.
- Conditions
- Sleep Apnoea, Obesity & Overweight, Sleep Apnea Syndrome, Obstructive
- Trial name
- TIRZE-PAP (NCT07846865)
- Testing
- Continuous Positive Airway Pressure, Tirzepatide
- Where
- Australia
- Volunteers
- 256 people
- Sponsor
- Woolcock Institute of Medical Research
Obesity
Evaluation of an Enhanced Delivery Model for Go NAPSACC
This study will compare the effectiveness and cost of Basic and Enhanced delivery models for Go NAPSACC on child care centers' use of evidence-based nutrition and physical activity practices.
- Trial name
- NCT03938103
- Testing
- Enhanced Go NAPSACC, Basic Go NAPSACC
- Where
- 2 sites in United States
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
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