Clinical trials: Obesity Overweight
Obesity (Disorder), Obesity
Effect of Vitamin D on Body Composition and Functionality of Older Adults
Older adults with obesity often experience a gradual loss of muscle mass and muscle strength, a condition sometimes described as sarcopenic obesity.
- Conditions
- Obesity (Disorder), Obesity, Sarcopenia, Sarcopenia in Elderly
- Trial name
- NCT07275177
- Testing
- Vitamin D
- Where
- Mexico
- Volunteers
- 29 people
- Sponsor
- Universidad Autónoma Benito Juárez de Oaxaca
Obesity, Overweight
AMAZE 13: A Research Study Investigating How Well the Medicine Zenagamtide Helps People in Asia With Excess Body Weight Lose Weight
The purpose of this clinical study is to find out if zenagamtide is safe and effective for treating people who have excess body weight. There are 2 study treatments in this study taken as injections under the skin once a week.
- Trial name
- AMAZE 13 (NCT07668401)
- Testing
- Zenagamtide
- Where
- 44 sites in India, Japan and 3 more
- Volunteers
- 400 people
- Sponsor
- Novo Nordisk A/S
Obesity & Overweight, Bariatric Surgery
Disordered Eating and Recurrent Weight Gain After MBS
Obesity represents an increasingly serious public health problem worldwide. According to the World Health Organization, one in eight individuals globally is affected by obesity.
- Conditions
- Obesity & Overweight, Bariatric Surgery, Weight Regain Post Bariatric Surgery, Eating Disorders
- Trial name
- NCT07434557
- Testing
- Observational assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Medipol University
Obesity
MPOWERed Messages: Tailored Mobile Messages to Enhance Weight Loss for Teens
Obesity affects millions of American children and increases their risk of adult obesity, a myriad of serious illnesses, increased healthcare costs, and premature death. It is vital to find ways to reverse this epidemic.
- Trial name
- NCT01448551
- Testing
- Tailored Mobile Messages to Enhance Weight Loss for Teens
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Childhood Obesity
Family Connections Weight Management
The prevalence of overweight children has increased significantly over the past 3 decades and 3 out of every 4 overweight children become obese adults.
- Trial name
- NCT00433901
- Testing
- Targeted parental instruction for positive lifestyle change with follow-up calls.
- Volunteers
- 220 people
- Sponsor
- Kaiser Permanente
Adults With Overweight and Obesity
A Feasibility Study of Mindfulness Training Transcranial Direct Current Stimulation (tDCS) in Adults With Overweight and Obesity
This study will investigate the feasibility of combining an app-based Mindfulness training (MT) with at-home administered transcranial direct current stimulation (tDCS) in adults with overweight or obesity and assess whether MT…
- Trial name
- MINDED (NCT05865912)
- Testing
- Mindfulness training + real tDCS
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- King's College London
Psoriasis
A Single-Center, Prospective, Pilot Study to Compare the Effect of Diet in Overweight or Obese Patients With Psoriasis on Light Therapy
Weight loss may help psoriasis. Phototherapy helps psoriasis. Combining the two treatments may help even more. Determining if a high protein diet vs a low protein diet results in improving psoriais may help lead to future dietary…
- Trial name
- NCT02193919
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bagel, Jerry, M.D.
Obesity
Effect of Intermittent Fasting on Fat Mass
This study is aimed to assess the different effect on fat mass between fasting (intervention) group and not fasting (control) group after 8 weeks 5:2 intermittent fasting (IF) among obese male student aged 18-25.
- Trial name
- NCT04245007
- Testing
- Fasting
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Universitas Indonesia
Obesity & Overweight
OBE2026 - Effect of One Year Intensive Lifestyle Treatment in Children With ISO-BMI Over 30kg/m² and Their Families.
Obesity has increased significantly in recent decades and is starting earlier than before, even before school age. In 2023, 8% of Finnish boys aged 7-12 and 4% of girls were obese, while the corresponding figures for boys aged…
- Trial name
- NCT07738029
- Testing
- Lifestyle Management
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Tampere University Hospital
Type2diabetes
Comparison of the Safety, Efficacy and Pharmacokinetics of DehydraTECH -CBD and DehydraTECH-GLP1 Agonists Alone or in Combination, in Overweight or Obese, Pre- and Type 2 Diabetic Participants
This is a Phase 1b, randomized, open-label, active-controlled, parallel, multiple-dose study comparing the safety, pharmacokinetics and efficacy of DehydraTECH Cannabidiol and Glucagon-like Peptide 1 (GLP-1) agonists alone and in…
- Trial name
- DehydraTECH (NCT06648031)
- Testing
- Arm 1 - DehydraTECH-CBD alone, Arm 2 - DehydraTECH-semaglutide alone, Arm 3 - DehydraTECH-CBD in combination with DehydraTECH-semaglutide
- Where
- 7 sites in Australia
- Volunteers
- 148 people
- Sponsor
- Lexaria Bioscience Corp.
Healthy, Obesity
A Study of LY3971297 in Healthy Participants
The purpose of this study is to measure side effects of LY3971297 injection administered under the skin in healthy participants and obese participants with high blood pressure (BP).
- Conditions
- Healthy, Obesity, Hypertension
- Trial name
- NCT06148272
- Testing
- LY3971297, LY3971297 IV
- Where
- 7 sites in United States, Japan and 1 more
- Volunteers
- 200 people
- Sponsor
- Eli Lilly and Company
Asthma, Obesity
Anti Inflammatory Lipid Mediators in Asthma Lipid Anti-Inflammtory Mediators in Asthma
The main purpose of this Phase 2 double blind, placebo controlled crossover clinical study is to demonstrate the efficacy and safety of CXA-10 in obese adult asthmatics.
- Trial name
- ALMA; LIMA (NCT03762395)
- Testing
- CXA-10
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Obesity in Childhood
Non-Pharmacologic Alternatives for Childhood Obesity
Childhood obesity is a global health issue. Mexico has been considered as the country with the higher number of children with obesity. There are not approved drugs to support diet and exercise as the first step to lose weight.
- Trial name
- NCT03670875
- Testing
- Agave inulin, Curcumin, O3FA
- Where
- Mexico
- Volunteers
- 300 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Overweight, Obesity
Telehealth for Weight Maintenance of African-American Women ("Exercise Your Faith")
Obesity can cause many health problems, including high blood pressure, diabetes, heart disease, and stroke. Although some people may lose weight through diet and exercise, many regain weight over time.
- Trial name
- NCT01402557
- Testing
- Weight Loss Church Program, Telephone Counseling, Telehealth Support
- Volunteers
- 88 people
- Sponsor
- University of Illinois Chicago
Obesity, Obesity, Abdominal
Immunometabolic Effects of Non-drug Strategies in the Clinical Management of Obesity: Translational Study
Forty women aged between 18 and 75 years-old with a BMI> 30kg/m2 are recruited to participate in the evaluation of their medical management.
- Conditions
- Obesity, Obesity, Abdominal, Obesity, Visceral, Female
- Trial name
- PPAR-NAPAS (NCT04436419)
- Testing
- Alpha lipoic acid (plus full hospitalization)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Fauqué
Growth Acceleration, Overweight or Obesity
Diet and Well-being of Young Danish Children
The overall objective with the study was to contribute to the scientific basis for dietary and life strategies, policies and dietary guidelines to infants and young children in Denmark and with special focus on prevention of…
- Conditions
- Growth Acceleration, Overweight or Obesity, Biomarkers of Metabolic Syndrome, Programming and Tracking
- Trial name
- SKOT I (NCT02170428)
- Where
- Denmark
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cardiovascular Disease, Obesity
Cooperative Lifestyle Programs (CLIP-II)
The aim is to study the effects of weight loss and weight loss combined with different types of physical activity on changes in physical functioning of older adults who are at-risk for cardiovascular disease.
- Conditions
- Cardiovascular Disease, Obesity, Physical Disability
- Trial name
- CLIP-II (NCT01547182)
- Testing
- Caloric restriction, Aerobic Training, Resistance Training
- Where
- 3 sites in United States
- Volunteers
- 249 people
- Sponsor
- Wake Forest University Health Sciences
Pediatric Obesity
Family-based Lifestyle Intervention Program and Carotenoid Supplementation for Children With Obesity
This is a pilot study of children between the ages of 8 to 11 years of age who are obese and participating in an intense family based intervention with a family-focused multi-component lifestyle intervention.
- Trial name
- NCT02060279
- Testing
- Lifestyle intervention and carotenoid supplements
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Cardiovascular Disease, Metabolic Syndrome
Absorption and Antioxidant Effects of Polyphenolics From Acai
A human clinical consumption trial will be performed in volunteers with increased risk factors for cardiovascular disease (Metabolic Syndrome), which includes obesity and diabetes and related conditions over a period of 12 weeks…
- Conditions
- Cardiovascular Disease, Metabolic Syndrome, Obesity
- Trial name
- NCT02227628
- Testing
- Acai polyphenolics, Sugary Beverage
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Obesity, Obesity, Morbid
Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss
The Investigators propose suture plication placement at the distal gastric body drives a significant portion of weight loss in endoscopic sleeve and sutures only need to be placed in the distal gastric body.
- Conditions
- Obesity, Obesity, Morbid, Metabolic Disease, Weight, Body
- Trial name
- NCT06299644
- Testing
- Endoscopic Sleeve Gastroplasty - Belt and Suspenders, Endoscopic Sleeve Gastroplasty - Belt
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
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