Clinical trials: Obesity Overweight
Weight Loss
Intermittent Fasting, Caloric Restriction and Body Composition in Obese Men and Women
This study systematically quantified the effects of intermittent fasting and caloric restriction (IFCR) on total and regional (abdominal) body composition (lean mass and fat mass), blood lipids, toxins, oxidative stress…
- Trial name
- NCT02525419
- Testing
- Weight Loss Phase, HP-IF, HH
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Ischemic Heart Disease, Myocardial Infarction
Polyamine Treatment in Elderly Patients With Coronary Artery Disease
The present study is testing spermidine treatment in elderly patients with coronary artery disease. The study is a randomized, double-blind, placebo-controlled, two-armed, parallel-group, single centre, clinical study.
- Conditions
- Ischemic Heart Disease, Myocardial Infarction, Cardiovascular Diseases, Hypertensive Heart Disease
- Trial name
- PolyCAD (NCT06186102)
- Testing
- Spermidine
- Where
- Denmark
- Volunteers
- 187 people
- Sponsor
- University of Aarhus
Obesity, Overweight
GoalTracker: Comparing Self-Monitoring Strategies for Weight Loss
This study is a randomized controlled trial that compares 3 self-monitoring approaches for weight loss. GoalTracker is a standalone, technology-based intervention using a commercial smartphone app (MyFitnessPal) and email.
- Conditions
- Obesity, Overweight, Weight Loss
- Trial name
- NCT03254953
- Testing
- self-monitoring of body weight, self-monitoring of diet, weekly personalized feedback + lessons + action plans
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Duke University
Healthy
Study Evaluating Effects of Multiple-Dose Administration of Itraconazole on the Single Dose Pharmacokinetics of Conjugated Estrogens/Bazedoxifene in Non-Obese and Obese Postmenopausal Women
This study will assess if itraconazole will affect the blood levels of Duavee when they are given together. This study will also assess if a subject's body size affects the blood levels of Duavee.
- Trial name
- CE/BZA (NCT02100553)
- Testing
- CE/BZA, Itraconazole
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Obesity, Sleep Restriction
Effects of Time of Sleep Restriction in Obesity
The purpose of this study is to determine the effect of different time of sleep restriction on control of food intake and metabolism of obese and normal subjects.
- Conditions
- Obesity, Sleep Restriction, Appetite Regulation, Eating
- Trial name
- NCT01259895
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Pregnancy, Obese
Validation of Ultrasound in Predicting a Low Lying Placenta Throughout Pregnancy
This is a prospective observational study comparing venous Doppler flow in the lower extremities of pregnant women. Pregnant women with a BMI >/= 30 will be compared to those with a BMI < 30.
- Trial name
- NCT02689739
- Testing
- venous duplex ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Obesity, Traditional Chinese Medicine
Observation on Obesity Undergoing XOWI
Obesity becomes a worldwide chronic health problem, including China. Meta-analyses showed in recent years anti-obesity effects of Chinese herbal therapy (CHT) in overweight and obese patients.
- Trial name
- NCT05122936
- Testing
- XRXPY-based Obesity Wellness Intervention(SOWI)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Feng Tao
Obesity, Colorectal Carcinoma
Legume Diet Satiety Pilot Study
This pilot study is designed to test the effects of a high legume (dried bean) diet on hunger and other indicators of health over the course of eight weeks, compared to a more conventional healthy diet.
- Trial name
- NCT02269631
- Testing
- Legume diet group, Control diet group, Smartpill
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University
Morbid Obesity
Evaluation of Endostapled Anastomoses for Laparoscopic Gastric Bypass (EEA-LGB)
Laparoscopic gastric bypass surgery is a common procedure being performed for the treatment of morbid obesity. The procedure consists of a creation of a small gastric pouch and rerouting the small bowel to bypass the stomach and…
- Trial name
- EEA-LGB (NCT00254072)
- Testing
- 3.5 mm vs 4.8 mm Stapler During Laparoscopic Gastric Bypass
- Where
- 6 sites in United States
- Volunteers
- 355 people
- Sponsor
- University of California, Irvine
Overweight, Obesity
Effects of WB-EMS and Protein Supplementation on LBM Maintenance During Intended Weight Loss
The present study aimed to determine the effect of different interventions on lean body mass maintenance under weight loss conditions in overweight and obese premenopausal women.
- Conditions
- Overweight, Obesity, Abdominal Obesity
- Trial name
- NCT03746977
- Testing
- Protein, Walking, WB-EMS application
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Obesity
Ripple Effect of Lifestyle Intervention During Pregnancy on Partners' Weight
The primary aim of the proposed study is to determine whether lifestyle interventions to prevent excessive gestational weight gain in overweight/obese pregnant women have positive "ripple" effects on untreated partners in the…
- Trial name
- NCT01770028
- Where
- 3 sites in United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Healthy, Obesity
Study on Energy Cost Prediction of Cycle Ergometer
This study purpose is (1) to develop the new energy expenditure equation; (2) to increase accuracy of energy cost prediction of cycle ergometer; (3) to find out some dependent factors.
- Trial name
- NCT01077219
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Obesity
Dermatome Electrical Stimulation on Individuals With Overweight and Class I Obesity
Investigators are doing this research study to find out the effect of T6 dermatomal electrical stimulation (delivered by a Transcutaneous Electrical Nerve Stimulation (TENS) unit) on appetite and weight loss.
- Trial name
- NCT03261531
- Testing
- Transcutaneous electrical nerve stimulation (TENS)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Mayo Clinic
Rectal Cancer, Obesity
Does Obesity Increase the Risk of Conversion and Short Term Complications in Laparoscopic Rectal Surgery?
Obesity is on the rise in the Western population and BMI has been shown to be associated with an increased risk of per- and postoperative complications.
- Trial name
- NCT02153853
- Where
- Denmark
- Volunteers
- 335 people
- Sponsor
- Hvidovre University Hospital
Polycystic Ovary Syndrome (PCOS), Menstrual Irregularity
Ovarian Ultrasonography for the Clinical Evaluation of Polycystic Ovary Syndrome
The investigators would like to determine how aspects of adiposity and age influence ultrasound features of the ovaries which are used to diagnose polycystic ovarian syndrome (PCOS).
- Conditions
- Polycystic Ovary Syndrome (PCOS), Menstrual Irregularity, Overweight and Obesity
- Trial name
- NCT03547453
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Cornell University
Overweight, Obesity
A Research Study Looking Into How Cagrilintide Influences Food Intake and Appetite in People With Overweight or Obesity
The study is testing cagrilintide, a study medicine, to understand how it affects food intake and appetite in people with overweight or obesity.
- Trial name
- NCT07557953
- Testing
- Cagrilintide
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Novo Nordisk A/S
Pre-diabetes
Preventing Diabetes in the Deep South: Extending Partnerships and Adapting Interventions to Reach Rural Communities at High Risk.
Diabetes is responsible for a huge and growing burden of patient suffering and social costs, and the impact of this disease is shared disproportionately by minorities and in rural resource-challenged communities, particularly in…
- Trial name
- NCT04343872
- Testing
- Receive lifestyle modification alone, Metformin therapy
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cardiovascular Diseases, Obesity
School-Based Intervention to Increase Physical Activity Among Adolescent Females
Physical inactivity is a major public health problem in the United States. Research has shown that physical activity levels decline during adolescence, and the decline is greater in females than males.
- Trial name
- NCT00296101
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Physical Activity, Obesity
MoTHER Buddy Program
The purpose of the 12-week study is to determine if competing a physical activity program with a buddy helps increase daily physical activity when compared to completing the same physical activity program without a buddy.
- Trial name
- NCT02338765
- Testing
- mHealth Physical Activity, Buddy-partnered exercise
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Overweight and Obesity
Effect of the Probiotic SF68® on Body Composition and Low-to-moderate Cardiovascular Risk
Obesity is a multifactorial disorder of energy balance, characterized by an imbalance between energy intake and energy consumption. In recent decades, the prevalence of obesity has reached epidemic proportions.
- Trial name
- NCT06795607
- Testing
- Probiotic
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
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