Clinical trials: Obesity Overweight
Bariatric Surgery Candidate, Obesity
The Effect of Exercise in Patients Awaiting Bariatric Surgery
The aim of this project is to understand the impact of a four week preoperative exercise programme on fitness and metabolic rate and weight before surgery.
- Trial name
- BariPrehab (NCT05235945)
- Testing
- Online exercise intervention
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University College, London
Obesity
National Registry of Obesity Treatment by Endosleeve
Obesity and overweight have emerged as public health problems of a pandemic nature, significantly reducing the life expectancy of those affected.
- Trial name
- NCT06657339
- Testing
- Therapeutic endoscopy endosleeve using a gastric suturing device (OverStitch™/Endomina™)
- Volunteers
- 354 people
- Sponsor
- Société Française d'Endoscopie Digestive
Healthy, Overweight
Effects of Pioglitazone on Insulin Sensitivity in Healthy Overweight and Obese Males (MK-0000-170)
The purpose of this study is to evaluate whether 30 mg of pioglitazone administered once daily for up to 28 days to healthy overweight and obese subjects will lead to a significant change in insulin sensitivity, measured in the…
- Conditions
- Healthy, Overweight, Obesity
- Trial name
- NCT01115712
- Testing
- Comparator: Pioglitazone, Comparator: Hyperinsulinemic Euglycemic Clamp
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Obesity, Diabetes
SOAR-2: Intervening in Obesity Through Reduction of Dietary Branched Chain Amino Acids
One of the primary risk factors for the development of diabetes is obesity. While even moderate weight loss achieved by dieting can lead to improvements in metabolic health, reduced-calorie diets are notoriously difficult to…
- Trial name
- SOAR-2 (NCT04424537)
- Testing
- Control diet, Low branched-chain amino acids(BCAA) diet, Low protein diet
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cardiovascular Diseases, Heart Diseases
Hypertension Prevention Trial (HPT) Feasibility Study
To test the feasibility and the efficacy of nutritional interventions in the primary prevention of hypertension in individuals predisposed to the development of hypertension; specifically, to test the hypothesis that reduction of…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Obesity
- Trial name
- NCT00000501
- Testing
- diet, sodium-restricted, diet, reducing, potassium
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Apnea, Obstructive Sleep, Obesity
Association of Body Fluid Distribution With Obstructive Sleep Apnea in Pregnant Women With Body Mass Index ≥ 40 kg/m2
Obstructive Sleep apnea (OSA) is a common and underdiagnosed condition in obese pregnant women with serious and life-threatening complications to the mother and baby.
- Trial name
- NCT04187612
- Testing
- Bioelectrical Impedance Analysis (BIA)
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Prader-Willi Syndrome
Regulating Together for Prader-Willi Syndrome: A Group Behavioral Therapy for Emotion Dysregulation
The goal of this study is to help teens with Prader-Willi Syndrome (PWS) and their families learn practical strategies for managing issues like irritability, meltdowns, and anxiety.
- Trial name
- RT-PWS (NCT07607730)
- Testing
- Regulating Together group therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Mercy Hospital Kansas City
Prevention of Childhood Obesity, Community Health Education
EFFECT OF A ONLINE NUTRITION EDUCATION PROGRAM IN PRESCHOOLER'S FAMILIES ON THEIR ADHERENCE TO THE MEDITERRANEAN DIET
Questions: What's the effect of an online nutritional educational program in preschoolers families on the adherence to the mediterranean diet? What's the effect of this program on the BMI at 3 years follow-up? Study Description A…
- Trial name
- ELIKUME (NCT06828367)
- Testing
- Online family educational intervention and cooking workshop
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fundacion Miguel Servet
Osteoarthritis, Knee, Osteoarthritis, Hip
OA Clinic-Community CARE Model
The purpose of this study is to test the OA Clinic-Community CARE Model (OA CARE) which will address all recommended components of knee/hip (osteoarthritis) OA care, include interventions for both patients and primary care…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Overweight, Obesity
- Trial name
- OA CARE (NCT05349500)
- Testing
- OA CARE Intervention, Usual Care control group
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Diabetes Mellitus, Overweight
Effectiveness and Safety of Salba on Weight Loss in Overweight Individuals With Type 2 Diabetes
Canadian statistics indicate that the incidence of obesity is increasing and that the occurrence of diabetes in obese individuals is 5-fold greater than those with a healthy weight, making weight control in this population…
- Conditions
- Diabetes Mellitus, Overweight, Obesity
- Trial name
- LOSS (NCT01403571)
- Testing
- Salba (Salvia hispanica L.), Oat-based Control
- Where
- Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Morbid Obesity
Surgical Conditions During Laparoscopic Bariatric Surgery
Obesity affects more than 78 million adults in the United States and it is estimated that 35% of the US population is obese. Currently, more than 179,000 bariatric procedures are performed in the US each year with the majority of…
- Trial name
- NCT02703909
- Testing
- Rocuronium, Insufflation pressure
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Missouri-Columbia
Obesity
A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight
This study will look at how well CagriSema helps people with excess body weight lose weight. CagriSema is a new medicine developed by Novo Nordisk that combines cagrilintide and semaglutide.
- Trial name
- NCT06388187
- Testing
- Cagrilintide, Semaglutide
- Where
- 25 sites in United States, Canada and 3 more
- Volunteers
- 300 people
- Sponsor
- Novo Nordisk A/S
Obesity, Childhood Obesity
Implementing Prevention Plus for Childhood Overweight and Obesity in Food Secure and Insecure Families
The ability of Prevention Plus to improve weight status when delivered by primary care providers is unknown, and the influence of household food security status as a moderator in the treatment of childhood obesity has never been…
- Trial name
- NCT02684214
- Testing
- Prevention Plus +, Prevention Plus -
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Obesity
Promoting Long-term Behavior Change to Reduce CVD Risk
Once intervention class or staff contact is removed, obese adults participating in behavioral weight-loss programs often give up healthy eating habits and regain weight.
- Trial name
- NCT00227006
- Testing
- Behavioral lifestyle/weight-loss intervention
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity, Abdominal
Long-term Metabolic Effects of Cafestol
Twelve-week double-blinded, placebo-controlled, parallel intervention study on 40 participants with a large waist circumference who will ingest cafestol or placebo capsules twice daily.
- Trial name
- NCT05672433
- Testing
- Cafestol
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Obesity
Cytokine Levels of Patients Who Underwent Obesity Surgery
Obesity is an important public health problem worldwide. There are large regional differences in the prevalence of overweight and obesity. Obesity is a growing problem in both developed and low-income countries.
- Trial name
- NCT04540263
- Testing
- Flow Cytometric analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Training and Research Hospital
Asthma
Antioxidant Therapy in Lean and Obese Asthmatics
This project will assess the effectiveness of antioxidant supplementation with common vitamins A, C, E and selenium in controlling asthma symptoms among lean and obese asthmatics.
- Trial name
- ALOA (NCT01317563)
- Testing
- Vitamins A, E, C & Selenium
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Nemours Children's Clinic
Obesity, Overweight and Obesity
Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity
Obesity, affecting 40% of US adults and costing 173b annually, represents a significant health care burden (1). It is associated with increased risk for multiple chronic diseases including hypertension, type 2 diabetes (T2D)…
- Conditions
- Obesity, Overweight and Obesity, Overweight
- Trial name
- NCT05912621
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Stanford University
Type 2 Diabetes Mellitus, Obesity
Soluble Dietary Fibres in the Prevention of Type 2 Diabetes Mellitus
Controlling the glycemic impact of foodstuffs (by reducing the glycemic load of the diet by using soluble dietary fibres) may reduce the glycemic or insulinemic response.
- Trial name
- NCT01163006
- Testing
- Polydextrose and soluble gluco fibre
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Overweight and Obesity
Study of Produce Prescription Programs in Adults With Overweight or Obesity Experiencing Nutrition Insecurity
The goal of this study is to understand the best practices for implementing produce prescriptions among adults with overweight or obesity experiencing nutrition insecurity.
- Trial name
- NCT06751563
- Testing
- Behavioral Text Messages and Produce Box Delivery, Behavioral Text Message Program and Produce Voucher
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Johns Hopkins University
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