Clinical trials: Obesity Overweight
Oncology, Metabolic Disease
Nutritional Safety and Metabolic Benefits of Oncometabolic Surgery for Obese Gastric Cancer Patients
The metabolic effect of oncometabolic surgery (long limb Roux-en Y reconstruction) for early gastric cancer patients has been revealed in a few pilot studies.
- Conditions
- Oncology, Metabolic Disease, Gastric Cancer
- Trial name
- ONCOMETAB (NCT03067012)
- Testing
- Oncometabolic reconstruction
- Volunteers
- 20 people
- Sponsor
- Seoul National University Bundang Hospital
Prader-Willi Syndrome
Regulating Together for Prader-Willi Syndrome: A Group Behavioral Therapy for Emotion Dysregulation
The goal of this study is to help teens with Prader-Willi Syndrome (PWS) and their families learn practical strategies for managing issues like irritability, meltdowns, and anxiety.
- Trial name
- RT-PWS (NCT07607730)
- Testing
- Regulating Together group therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Mercy Hospital Kansas City
Obesity, Insulin Resistance
Yoga Improves Aerobic Fitness, Glycemia and Mood State and Reduces Abdominal Obesity
Stretching and flexibility exercise such as yoga and functional resistance exercise are two forms of exercise that are growing in popularity.
- Trial name
- PRISE (NCT02190136)
- Testing
- Protein whole foods, Protein Resistance Exercise Training, Protein Stretching/Yoga Training
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Skidmore College
General Health and Wellness, Energy and Vitality
M4C Nutraceutical Intervention Human Health Effects Pilot
This 3 month pilot study will be an unblinded, convenience sampling, nutraceutical intervention trial. Twenty fasted subjects will undergo a baseline health assessment via a questionnaire, baseline clinical chemistries, blood…
- Conditions
- General Health and Wellness, Energy and Vitality, Cognitive Function and Mental Health, Weight Management
- Trial name
- M4C Pilot (NCT06476236)
- Testing
- M4C
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Concordia University Wisconsin
Pediatric Obesity
Family Focused Community Program to Prevent Type 2 Diabetes in Peripubertal Youth
Over one-third of children and adolescents are overweight and nearly 1 in 5 of them are obese. Metabolic syndrome, a strong predictor of Type 2 diabetes (T2D) and cardiovascular disease (CVD), occurs in up to 44% of obese youth…
- Trial name
- NCT02421198
- Testing
- YMCA Family Diabetes Prevention Program (YFDPP)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Prostate Cancer, Obesity
How Does Prostate Cancer Metastasize? Studying the Role of Secreted Packages (Exosomes) From Fat Tissue in Lean and Obese Patients
The investigators will be collecting prostate and fat tissue from participants undergoing radical prostatectomy to culture and study in the laboratory.
- Trial name
- EXOPRO (NCT04167722)
- Testing
- Robotic Radical Prostatectomy
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Imperial College London
Overweight, Obesity
A Scintigraphic Study to Investigate the Effect of Gelesis100 on Gastric Emptying in Overweight and Obese Subjects
The purpose of the study is to evaluate the gastrointestinal behaviour of a novel weight loss device in vivo to further understand the device's mechanism of action in aiding weight loss.
- Trial name
- NCT02487602
- Testing
- Gelesis100
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gelesis, Inc.
Obesity
A Facebook-based Weight Loss Programme for Obese Adults in Hong Kong
The purpose of this study is to determine the feasibility and efficacy of a 6-month weight loss intervention program for obese working adults through a popular social networking site - Facebook.
- Trial name
- NCT02616237
- Testing
- Lifestyle Intervention
- Where
- Hong Kong
- Volunteers
- 59 people
- Sponsor
- The Hong Kong Polytechnic University
Binge Eating Disorder
Phentermine/Topiramate Extended Release in Binge Eating Disorder (BED)
The goal of this project is to evaluate the effectiveness and tolerability of the novel weight management medication PHEN/TPM ER (Qsymia®)along with nutritional and lifestyle modification counseling in the treatment of binge…
- Trial name
- NCT02659475
- Testing
- PHEN/TPM ER (Qsymia®)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Lindner Center of HOPE
Morbid Obesity
Population PK/PD of Propofol in the Morbidly Obese Patient
Rationale: The extreme increase of obesity in the last years had led to this study. There is no consensus about how to anaesthetise morbidly obese patients.
- Trial name
- NCT00395681
- Testing
- Diprivan
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Nutritional Disorders, Obesity
TARGet Kids!: Measuring Nutrition in Young Preschool Children in the Primary Care Practice Setting
TARGet Kids! (The Applied Research Group for Kids) is a research study enrolling healthy children aged 0-5 years. The aim of the TARGet Kids! registry is to link early life exposures to health problems including obesity…
- Conditions
- Nutritional Disorders, Obesity, Development
- Trial name
- TARGetKids! (NCT01869530)
- Where
- 3 sites in Canada
- Volunteers
- 14,000 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Overweight, Obesity
Real-World Patient and Physician Experience With Semaglutide Across Six Emerging Markets
The purpose of this study is to assess semaglutide's impact on daily life from participants and physicians experience.
- Trial name
- NCT07850765
- Testing
- Semaglutide
- Where
- 6 sites in Israel, Mexico and 4 more
- Volunteers
- 1,260 people
- Sponsor
- Novo Nordisk A/S
Overweight, Obese
Weight Loss and Healthy Diet Through Mobile Phone-enabled Social Interactions
A randomized controlled trial comparing the effects of the social-enabled internet weight loss and diet change intervention with the delayed treatment group for 3 months.
- Trial name
- NCT01957800
- Testing
- Website, Usual Care
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Milton S. Hershey Medical Center
Obesity and Overweight, Type 2 Diabetes
Sleep, Glucose, and Brain Health in Obesity and Overweight Individuals
The primary aim of the NNF study is to investigate both cross-sectional and longitudinal associations between sleep patterns-measured over two consecutive weeks at baseline and again one year later-and indicators of glycemic…
- Conditions
- Obesity and Overweight, Type 2 Diabetes, Sleep, Brain Health
- Trial name
- NNF (NCT06968728)
- Volunteers
- 400 people
- Sponsor
- Uppsala University
Obesity
IG vs ID Bitter Administration
We want to investigate whether bitter compounds, denatonium benzoate and quinine hydrochloride, have a distinct effect on gastrointestinal hormone release after infusion into the stomach or duodenum.
- Trial name
- IG vs ID (NCT03985865)
- Testing
- Intragastric quinine hydrochloride, Intragastric denatonium benzoate, Intraduodenal quinine hydrochloride
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity, Heart Diseases
Evaluating a Messaging Campaign in the United States
Purpose: To evaluate reactions to and opinions of a messaging campaign. Participants: Participants will be recruited through Prime Panels and will be US-based adults (18 years old and older) who consumed red meat in the past 30…
- Conditions
- Obesity, Heart Diseases, Cancer
- Trial name
- NCT04562636
- Testing
- Environmental message, Health message, Neutral Message
- Where
- United States
- Volunteers
- 1,244 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Severe Obesity
Enhancing Weight Loss Maintenance With GLP-1RA (BYDUREON™) in Adolescents With Severe Obesity
Long-term weight loss maintenance is seldom achieved by individuals with obesity owing to numerous biological adaptations involving appetite, satiety, and energy expenditure in the post- weight loss setting.
- Trial name
- NCT02496611
- Testing
- Weight loss with pharmacotherapy, Weight loss without pharmacotherapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity
Weight Gain in First-year University Students
The transition to university from secondary school comes with many changes to living arrangements, dietary and alcohol intake, physical activity, and stress.
- Trial name
- NCT05856734
- Testing
- Weight and body composition change, Change in dietary intake, Change in physical activity
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Obesity or Overweight
A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity
This study will evaluate the efficacy and safety of petrelintide compared with placebo, in conjunction with a reduced-calorie diet and increased physical activity, for weight management in participants living with overweight or…
- Trial name
- ZUPREME-3 (NCT07843498)
- Testing
- Petrelintide
- Where
- 3 sites in United States
- Volunteers
- 3,900 people
- Sponsor
- Hoffmann-La Roche
Metastatic Breast Cancer, Estrogen-receptor-positive Breast Cancer
The FEMA Study: Feasibility of Exercise in Patients With Metastatic Breast Cancer and Adiposity
The goal of this clinical trial is to test a physical activity program in patients with metastatic breast cancer and overweight receiving endocrine-based treatment.
- Conditions
- Metastatic Breast Cancer, Estrogen-receptor-positive Breast Cancer, Adiposity
- Trial name
- NCT06343987
- Testing
- Physical Activity
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Aarhus University Hospital
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