Clinical trials: Obesity Overweight
Body Mass Index Quantitative Trait Locus 5 Disorder, Tangier Disease
Effect of High Protein Diet on Adiponectin and Inflammation Among Overweight and Obese Children
The investigators aimed to determine the effects of HP diet on adiponectin and inflammatory factors among overweight and obese children.
- Trial name
- NCT01886495
- Testing
- nutrition intervention
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Obesity, Insulin Resistance
Regional Fat Depots and Insulin Resistance
The biological basis for insulin resistance associated with obesity is unknown. By studying equally-overweight/obese individuals who are either insulin resistant or insulin sensitive, the investigators will compare…
- Conditions
- Obesity, Insulin Resistance, Diabetes Mellitus Type 2
- Trial name
- NCT01336777
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Stanford University
Asthma, Obesity
Effects of Weight Loss in Obese Difficult-to-treat Asthmatics
Sixty percent of patients with difficult to control asthma seen in our outpatient clinic are obese. The impact of weight reduction in this subpopulation of asthmatics has not been studied.
- Conditions
- Asthma, Obesity, Weight Loss
- Trial name
- NCT01047657
- Testing
- Low caloric diet plus orlistat and sibutramine
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- University of Sao Paulo General Hospital
Obesity, ESRD
Bariatric Surgery for ESRD Patients vs Control
This study will address a true clinical problem by developing a risk/benefit analysis for rapid surgical weight loss in the ESRD population.
- Trial name
- NCT00580762
- Testing
- Roux-en-y gastric bypass (RYGB)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Obesity, Bariatric Surgery Candidate
Brain Gut Axis Changes After Bariatric Surgery and Their Relationship to Weight Loss
Assessing the changes in the brain-gut axis after weight loss surgery and their relationship with weight loss and changes in eating behaviors.
- Trial name
- NCT04429386
- Testing
- Bariatric surgery
- Volunteers
- 22 people
- Sponsor
- University of California, Los Angeles
Obesity and Hypogonadism
Lifestyle Intervention and Testosterone Replacement in Obese Seniors
The prevalence of obesity in Veterans is greater than in the general population, and even more so among users of the VA Health Care System.
- Trial name
- LITROS (NCT02367105)
- Testing
- Testosterone, Lifestyle Therapy
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- VA Office of Research and Development
Insulin Resistance, Obesity
Financial Incentives to Exercise for Adolescents
Among youth populations, American Indians have the highest prevalence of diabetes in the United States. This study will use exercise as the principal lifestyle modification approach to reduce the risk of diabetes in this…
- Conditions
- Insulin Resistance, Obesity, Sedentary Lifestyle
- Trial name
- MOVE (NCT01848353)
- Testing
- Exercise training
- Where
- 2 sites in United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Obesity
Pediatric Hypothalamic Obesity
This trial is being conducted in pediatric patients with Hypothalamic Obesity. This generally occurs in people who have had an injury to or tumor in their hypothalamus (gland or organ that secretes hormones).
- Trial name
- NCT00076362
- Testing
- Sandostatin LAR
- Where
- 15 sites in United States
- Volunteers
- 60 people
- Sponsor
- Novartis Pharmaceuticals
Morbid Obesity, Steatohepatitis
Identification of Protective and Worsening Steatohepatitis (NASH) Factors
The main aim of this work will be to identify a profile of gene expression by microarray in the liver which might allow to differentiate obese subjects having a normal liver from those with steatohepatitis or steatosis.
- Conditions
- Morbid Obesity, Steatohepatitis, Steatosis
- Trial name
- NCT00914446
- Testing
- hepatic biopsies
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Obesity & Overweight, Type 2 Diabetes
Hydration Intervention to Decrease Side Effects Associated With GLP - 1 RA Therapy
This is a 17 - week study consisting of a one - week run - in period and a 16 - week intervention. The 16 - week pilot interventions aims to increase hydration in those beginning GLP - 1 RA therapy.
- Conditions
- Obesity & Overweight, Type 2 Diabetes, Type 2 Diabetes (Adult Onset), Obesity Type 2 Diabetes Mellitus
- Trial name
- NCT07641361
- Testing
- Hydration Plus, Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- State University of New York at Buffalo
Heart Failure, Obesity
BMI-Driven Tolerability and Efficacy of Entresto in Heart Failure Patients
This study aims to determine if patients with higher BMI can tolerate higher doses of Entresto (sacubitril/valsartan) and experience better symptomatic and functional outcomes compared to patients with lower BMI.
- Trial name
- BETTER-HF (NCT06439069)
- Where
- Lithuania
- Volunteers
- 340 people
- Sponsor
- Lithuanian University of Health Sciences
Obesity, Diabetes
Penn Medicine Food Market Study
The goal of this interventional study is to test ways to improve the effectiveness of a healthy foods prescription program in increasing the purchase of healthy foods for patients who have both obesity (BMI >or= 30) and diabetes…
- Trial name
- NCT06283394
- Testing
- Storefront Choice Architecture, Fresh Funds, Loss Framing
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- University of Pennsylvania
Diabetes Mellitus, Type 2, Obesity
Impact of a Regional Program Agir Sur Sa SantE
The prevention and control of lifestyle-related non-communicable chronic diseases, including diabetes, obesity and cardiovascular disorders, that share common risk factors, has now become a major focus of the World Health…
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Hypertension, Dyslipidemias
- Trial name
- NCT02478853
- Testing
- Implementation of a new regional care framework
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- Université de Sherbrooke
Postoperative Nausea and Vomiting, Laparoscopic Sleeve Gastrectomy
Baclofen in Preventing Postoperative Nausea and Vomiting After Bariatric Surgery
This study aims to evaluate the possible efficacy of baclofen on postoperative nausea and vomiting in patient with morbid obesity who will undergo laparoscopic sleeve gastrectomy.
- Conditions
- Postoperative Nausea and Vomiting, Laparoscopic Sleeve Gastrectomy, Morbid Obesity
- Trial name
- NCT05516953
- Testing
- Baclofen Tablets
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tanta University
Childhood Obesity, Physical Activity
Development and Feasibility of an Intervention to Increase Physical Activity Among Young Children
The aim of this study is to develop, implement, and evaluate a novel intervention to increase physical activity and reduce sedentary behaviour among pre-school children, with the ultimate goal of reducing obesity among this age…
- Trial name
- NCT05754359
- Testing
- I'm an Active Hero (IAAH) Intervention Program
- Where
- Saudi Arabia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Osteoarthritis, Obesity
Multi-parametric Imaging of the Knee in Obese Patients With Knee Osteoarthritis; Weight Maintenance
This is a substudy to a randomised trial investigating the effect of liraglutide on body weight and pain in overweight or obese patients with knee osteoarthritis (NCT02905864).
- Trial name
- IM-LOSEIT-II (NCT02928679)
- Testing
- Liraglutide 3 mg (Saxenda)
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Henrik Gudbergsen
Obesity, NAFLD
The Impact of Bariatric Surgery on Non-alcoholic Fatty Liver Disease
Up to 300 million people have a BMI over 30kg/m2. Obesity is the cause of many serious diseases, such as type 2 diabetes, hypertension and NAFLD.
- Trial name
- NCT02828579
- Testing
- Bariatric surgery
- Volunteers
- 20 people
- Sponsor
- Jagiellonian University
Cardiovascular Diseases, Coronary Disease
Genetics of Atherosclerosis in Mexican Americans
To identify individual genes that contribute to variation in susceptibility to coronary heart disease (CHD) in Mexican Americans.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Obesity, Atherosclerosis
- Trial name
- NCT00005462
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity, Abdominal
Effects of Aerobic and Resistance Training on Abdominal Fat Loss
Study the effects of different exercise modes on total and regional adiposity variation in subcutaneous and visceral adipose tissue (VAT and SAT).
- Trial name
- NCT03700827
- Testing
- Resistance Training, Aerobic Training
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Southern Illinois University Edwardsville
HIV Infections, Obesity
Effect of Biktarvy & Symtuza on microRNAs in HIV and Correlation With Weight Gain
The purpose of this research study is to understand why certain HIV medication regimens (called anti-retroviral or ARV medications) cause more weight gain than others.
- Trial name
- NCT05463783
- Testing
- Biktarvy, Symtuza
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- East Carolina University
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