Clinical trials: Obesity Overweight
Pregnancy, Overweight and Obesity
Diabetes Prevention Program Feasibility Study of Breastfeeding
The purpose of this study is to learn about the impact of the Diabetes Prevention Program (DPP) coupled with intensive breastfeeding support to help overweight or obese pregnant women lose weight postpartum, improve their blood…
- Trial name
- NCT04021602
- Testing
- Diabetes Prevention Program, Breastfeeding Education, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of Kansas Medical Center
Pediatric Obesity
Development of the DRIVE Curriculum to Address Childhood Obesity Risk Factors
The purpose of this study is to help overweight or obese children to maintain or reduce their body mass index (BMI) through the home-based parent training program the investigators developed called DRIVE.
- Trial name
- NCT02160847
- Testing
- DRIVE Program
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Georgia State University
Schizophrenia, Schizoaffective Disorder
Demonstrate the Effects of Pramlintide on Weight Reduction in Schizophrenia
Primary Objective: To test the effect of pramlintide on body weight in clozapine- and olanzapine-induced weight gain in persons with schizophrenia who are currently taking either drug; measures of the metabolic syndrome will be…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Diabetes, Weight Gain
- Trial name
- NCT00690235
- Testing
- Pramlintide
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Texas Southwestern Medical Center
Overweight, Obesity
Research Study Investigating How Well NNC0174-0833 Works in People Suffering From Overweight or Obesity.
This study will look at the change in body weight in people taking NNC0174-0833, liraglutide and "dummy" medicine, from the start to the end of the study.
- Trial name
- NCT03856047
- Testing
- NNC0174-0833, Liraglutide 3.0 mg
- Where
- 54 sites in United States, Canada and 8 more
- Volunteers
- 706 people
- Sponsor
- Novo Nordisk A/S
Obesity
Pilot Study of Time Restricted Feeding as a Weight Loss Intervention
The circadian timing of Energy Intake (EI) has emerged as a key factor in the regulation of body weight. Studies have suggested that eating later in the evening or at night when the circadian system is promoting sleep adversely…
- Trial name
- NCT03571048
- Testing
- Reduced Calorie Diet (RCD), Time Restricted Feeding (TRF)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity
Phase 2a Placebo-Controlled Study of VTX3232 Alone or in Combination With Semaglutide in Obesity
This study evaluated the safety of VTX3232 administered alone or in combination with semaglutide in participants with obesity. Approximately 160 participants were randomized to receive VTX3232 30 mg, placebo, VTX3232 30 mg in…
- Trial name
- NCT06771115
- Testing
- VTX3232 30 mg, VTX3232 30 mg in combination with semaglutide
- Where
- 14 sites in United States
- Volunteers
- 175 people
- Sponsor
- Zomagen Biosciences Ltd.
Obesity, Overweight and Obesity
Investigation of the Effects of a Bifidobacterium Breve Strain on Fat Loss in Healthy Adults
Overweight has become a critical issue in North America and the market value of weight loss products is expected to rise as the population becomes more health-conscious and aware of the risks associated with excess body weight.
- Trial name
- NCT04677738
- Testing
- B. breve strain
- Where
- Canada
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Morinaga Milk Industry Co., LTD
Obesity, Diabetes
Framingham State Food Study
This study will evaluate the effects of dietary composition on energy expenditure and chronic disease risk factors, while also exploring physiological mechanisms underlying these effects.
- Conditions
- Obesity, Diabetes, Cardiovascular Disease
- Trial name
- (FS)2 (NCT02068885)
- Testing
- Feeding study
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Obesity
Tissue Penetration of Antibiotics in Obesity
The purpose of this study is to evaluate cefoxitin pharmacokinetics in obese surgical patients.
- Trial name
- NCT00752908
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Washington University School of Medicine
Obesity
Communicating Risk Information for Obesity
This study will examine the impact of providing genetic risk information for obesity on people's attitudes and beliefs about obesity, health behaviors and weight outcomes.
- Trial name
- NCT01355224
- Testing
- Genetic, Lifestyle
- Where
- United States
- Volunteers
- 798 people, healthy volunteers welcome
- Sponsor
- Boston University
Obesity, Insulin Resistance
Mineralocorticoid Receptor and Obesity Induced Cardiovascular Complications
The purpose of this study is to find out if spironolactone, a drug that blocks the action of aldosterone, can make the blood vessels work better in people with obesity.
- Trial name
- NCT01406015
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Brigham and Women's Hospital
Obesity
Weight Management Intervention in College: A Pilot Study
This Proof-of-Concept study consists of a series of uncontrolled pilot studies to refine a behavioral weight loss trial using a "small change" approach for emerging adult college students with overweight/obesity.
- Trial name
- NCT05895461
- Testing
- BWLI-College, Control
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- The Miriam Hospital
Obesity
Peer-Led Healthy Lifestyle Program in Supportive Housing
This goal of this randomized controlled effectiveness trial is to compare the effectiveness of a peer-led health lifestyle intervention (Peer GLB) versus usual care services in supportive housing agencies in New York City and…
- Trial name
- NCT02175641
- Testing
- Peer-Led Group Lifestyle Balance, Usual Care Services
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- Washington University School of Medicine
Obesity
The Beneficial Effects of Healthy Snacks on Appetite Control, Satiety, and Reward-driven Eating Behavior in Young People
The purpose of this study is to examine the effects of normal vs. protein-rich afternoon snacks on appetite control, satiety, and reward-driven eating (particularly in the evening) in young people.
- Trial name
- NCT01781286
- Testing
- High Protein, Low Protein
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obesity, Leprosy
Effect of Weight and/or Obesity on Dapsone Drug Concentrations
This study will find how weight affects the dosing of a drug called dapsone. Currently, the amount of dapsone a patient receives is the same regardless of the patient's weight.
- Conditions
- Obesity, Leprosy, Tuberculosis
- Trial name
- NCT01165840
- Testing
- Dapsone
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Prader-Willi Syndrome
Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome
The purpose of this study was to evaluate the effects of a once daily subcutaneous injectable formulation of setmelanotide in obese participants with Prader-Willi syndrome on tolerability, weight loss, and hyperphagia-related…
- Trial name
- NCT02311673
- Testing
- Setmelanotide
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Obesity
MOWI Home-Based Pilot
The goal of this study is to conduct a program of pilot research aimed at developing and evaluating a technology-assisted wellness intervention for older adults with obesity.
- Trial name
- NCT03104205
- Testing
- Evaluate home-based MOWI
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Morbid Obesity, Surgery
Oxygen Reserve Index: Utility as Early Warning for Desaturation in Morbidly Obese Patients
The Oxygen Reserve Index (ORi) is a reference that could help clinicians with their assessments of normoxic and hyperoxic states by scaling the measured absorption information between 0.00 and 1.00.
- Trial name
- NCT03021551
- Testing
- Rainbow sensor
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Masimo Corporation
Parental Stress, Parent and Child Stress
Family Based Mindfulness Intervention
The goal of the proposed interdisciplinary study is to assess feasibility of recruiting a pilot sample of parents of toddlers and engaging them in a pilot study to test a version of mindfulness-based intervention for parenting…
- Conditions
- Parental Stress, Parent and Child Stress, Parental and Child Obesity, Child Obesity
- Trial name
- NCT01974102
- Testing
- Lifestyle counseling, Parenting Mindfully for Health (PMH)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity
Endoscopic Suturing System for Tissue Apposition
The objective of this feasibility trial is to evaluate the Ethicon Endo-Surgery Endoscopic Suturing System (ESS) for tissue apposition and reduction of the size of a dilated GJ anastomosis in subjects who are regaining weight…
- Trial name
- NCT00495222
- Testing
- Tissue plication, Endoscopic Suturing System
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Ethicon Endo-Surgery
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