Clinical trials: Obesity Overweight
Overweight and Obesity
Preventing Weight Gain Among Those Who Decline Behavioral Weight Loss Treatment (STEADY)
The goal of this pilot trial is to pilot test an intervention to help prevent weight gain or produce weight loss among adults with obesity. Participants are asked to self-weigh on a smart scale for one year.
- Trial name
- STEADY (NCT04751656)
- Testing
- Steady Intervention
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Florida
Obesity
Obalon US Commercial Registry
Retrospective study of the data reported in the Obalon US Commercial Registry
- Trial name
- NCT03688256
- Testing
- Obalon Balloon System
- Volunteers
- 1,343 people, healthy volunteers welcome
- Sponsor
- Surgical Specialists of Louisiana
Obesity, Overweight
A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight
The main purpose of this study is to see how orforglipron affects the amount of body fat compared with placebo in participants with obesity or overweight. Participation in the study will last approximately 8 months.
- Trial name
- NCT06824051
- Testing
- Orforglipron
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- Eli Lilly and Company
Obesity, Cardiovascular Diseases
Naltrexone/Bupropion Cardiovascular Outcomes Study
The purpose of this study is to evaluate cardiovascular (CV) safety of naltrexone hydrochloride (HCl) and bupropion HCl extended release combination (NB) compared with placebo and rule out excess risk of major adverse…
- Trial name
- NCT02638129
- Testing
- Naltrexone HCl/Bupropion HCl ER
- Where
- 139 sites in United States
- Volunteers
- 67 people
- Sponsor
- Orexigen Therapeutics, Inc
Diabetes Mellitus, Cardiovascular Diseases
Estudo Longitudinal de Saúde do Adulto (Brazilian Longitudinal Study of Adult Health )
The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) aims to contribute with relevant information regarding the development and progression of clinical and subclinical chronic diseases, particularly cardiovascular…
- Trial name
- ELSA-Brasil (NCT02320461)
- Volunteers
- 15,105 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Metabolic Syndrome
P20 Extending Sleep to Reverse Metabolic Syndrome
This pilot study will test the acceptability and feasibility of a sleep extension intervention in community-dwelling, short-sleeping, racially/ethnically diverse middle-aged adults with MetS.
- Trial name
- NCT03596983
- Testing
- Sleep Intervention, Week 2 Intervention
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- NYU Langone Health
Cardiovascular Risk Factor, Prediabetes
Active You: A Novel Exercise Program for African Americans
Barriers to physical activity (PA) among African Americans (AAs) have been extensively studied, yet there is a paucity of innovative PA interventions designed to address them.
- Conditions
- Cardiovascular Risk Factor, Prediabetes, Overweight and Obesity, Sedentary Behavior
- Trial name
- NCT04280783
- Testing
- The Physical Activity for The Heart (PATH) intervention, Be Active Your Way Booklet
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity, Metabolic Syndrome
Diet, Obesity and Genes (DiOGenes)
Study Title: Diogenes, A randomised controlled trial comparing the effect of reduced-fat diets varying in glycaemic index (high vs. low) and protein content (high vs.
- Conditions
- Obesity, Metabolic Syndrome, Type 2 Diabetes, Cardiovascular Disease
- Trial name
- DIOGENES (NCT00390637)
- Testing
- High or low Glycemic Index and high or low Protein Diet
- Where
- Denmark
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy
A Study to Test How Well Different Doses of BI 3034701 Are Tolerated by Healthy Men and People With Overweight or Obesity
This study is open to healthy people and people with overweight or obesity. It has 2 parts. Part A is open to healthy men between 18 and 55 years of age.
- Trial name
- NCT06352437
- Testing
- BI 3034701
- Where
- Germany
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Diabetes
Jump Start Shared Medical Appointments for Diabetes With Weight Management
The proposed research will test a novel program that combines intensive weight management with shared (group) medical appointments for patients with diabetes.
- Trial name
- Jump Start (NCT01973972)
- Testing
- Weight management, Shared medical appointments (SMA)
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- VA Office of Research and Development
Menopause
The BALANCE Study - Improving Glucose Control Through Prebiotic Gut Health Drink in Postmenopausal Women
The menopausal transition is associated with a decline in oestrogen levels, contributing to adverse metabolic changes including increased central adiposity, systemic inflammation, and insulin resistance.
- Trial name
- BALANCE (NCT07565675)
- Testing
- ió everyday (a prebiotic- enriched gut health drink containing inulin)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Poly Cystic Ovary Syndrome, Overweight , Obesity
Physical Activity and Cardiometabolic Health in Women With or Without Polycystic Ovary Syndrome (SCOPAP)
The primary objective of this study is to investigate the effects of a multidisciplinary intervention, including a targeted adapted physical activity program, on lipid oxidation during a walking exercise in women with overweight…
- Trial name
- SCOPAP (NCT07659392)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Obese, Weight, Body
Evaluation of the Colonization Capacity of a Probiotic Bacterium.
The goal of this interventional study is to test the colonization of a new generation probiotic in normal weight and overweight/obese people.
- Trial name
- BIOPRED (NCT05878444)
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Valencian Innovation Agency
Behavior, Health, Obesity, Childhood
Food for Thought: Virtual Home-Based Family Interventions to Improve Nutrition Behaviors
A randomized controlled trial enrolling 123 parent-infant dyads (English or Spanish speaking) comparing a virtual video Teaching Kitchen Outreach Program (TKO) with weekly grocery delivery (comparator group), to Healthier…
- Trial name
- NCT05328193
- Testing
- Healthier Families, COVID Edition, Teaching Kitchen Outreach
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Obesity
Evaluation of the Absorption Rate From Different Oral Fe-supplements in Obese Volunteers Pre- and Post-RYGB
Obese volunteers who have scheduled a gastric bypass (RYGB) in UZ Leuven will be asked to participate in a cross-over study using commercial available iron supplements.
- Trial name
- NCT02569593
- Testing
- Iron supplements, more specific Ferrodyn and Vista Ferrum
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- KU Leuven
Obesity (BMI>30), Metabolically Healthy Obesity
Plasma Taurine in Older Women With Obesity: Impact of Metabolic Phenotype and Combined Exercise
Population aging has been accompanied by a rise in obesity and other chronic diseases, increasing cardiovascular risk particularly among women, who exhibit a higher prevalence in older age groups compared to men.
- Conditions
- Obesity (BMI>30), Metabolically Healthy Obesity, Metabolically Unhealty Obese
- Trial name
- non applicable (NCT07711899)
- Testing
- Physical Training of 16 weeks
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Fever, COPD
The Application of a Wireless Sensor Technology for Vital Statistics in CHILDREN AND ADULTS
The primary outcome for this project will be the development of a small, non-invasive wireless sensor that is linked to a conventional computer that can be used in health care for monitoring of acute and chronic health problems.
- Conditions
- Fever, COPD, Obesity, Congenital Heart Disease
- Trial name
- NCT01845506
- Testing
- Cardiorespiratory monitor, Wireless pressure sensor
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Obesity, Regional Anesthesia
Regional Anesthesia and Analgesia Techniques in Obese Patients
Obesity is a health problem throughout the world and has increasingly become a widespread epidemic all over the world and also in Turkey.
- Trial name
- NCT04197752
- Testing
- Regional anesthesia/analgesia techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Istanbul University
Obesity, Healthy
Gastrointestinal Tolerability to Agavins and Impact on Host-gut Microbiota-metabolism Interactions Modulation
Agavins are branched neo-fructans and prebiotic fiber found in Agave plants. In preclinical studies, agavins have demonstrated an effect in reversing metabolic disorders associated to overweight and obesity through the modulation…
- Trial name
- NCT04555447
- Testing
- Agavins (prebiotic fiber)
- Where
- 2 sites in Mexico
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Centro De Investigación Y De Estudios Avanzados Del Instituto Politécnico Nacional-Unidad Irapuato
Obesity
Food and Nutrition Education in Quilombolas Communities With Food Insecurity: Multi-sector Intervention
To optimize the food security in quilombolas communities with high prevalence of food insecurity and obesity, the present study proposes to test a multi-sector intervention including agriculture sectors, health professionals and…
- Trial name
- NCT02489149
- Testing
- Multi-sector interventions, Control
- Where
- Brazil
- Volunteers
- 4 people
- Sponsor
- Federal University of Rio Grande do Sul
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