Clinical trials: Obesity and Cardiovascular Risk
Hypertension, Type 2 Diabetes
Lifestyle Intervention in Primary Health Care - the Björknäs Study
The purpose of this study is to determine whether a short group intervention programe aiming at lifestyle changes at a local health centre can improve risk factors for cardiovascular disease
- Conditions
- Hypertension, Type 2 Diabetes, Obesity, Dyslipidemia
- Trial name
- NCT00486941
- Testing
- Exercise and diet - based on DPS and DPP
- Where
- Sweden
- Volunteers
- 151 people
- Sponsor
- Umeå University
Diabetes Mellitus, Hypertension
Impact of INsulin Sensitivity on Cardiovascular Risk Markers During 10-20 Years of FOllow up
The purpose of this study is to identify risk factors for insulin resistance and to investigate the influence of insulin sensitivity on development of cardiovascular risk markers like blood pressure, heart rate, body build…
- Conditions
- Diabetes Mellitus, Hypertension, Ischemic Heart Disease, Stroke
- Trial name
- INFO (NCT01412554)
- Where
- Norway
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Chronic Kidney Diseases, Diabetes
Precision Medicine Approach to Unravel the Risk Factors for Renal, Cardiovascular, Ophthalmologic, Neurologic and Hepatic Complications of Metabolic Disorders
There is currently no way to predict the progression of chronic kidney disease in patients with metabolic disease(s). Furthermore, the mechanisms responsible for the development and/or progression of complications remain largely…
- Conditions
- Chronic Kidney Diseases, Diabetes, Obesity
- Trial name
- PRECIMETAB (NCT05307172)
- Where
- France
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Cardiovascular Diseases, Heart Diseases
HYPGENE-Genetics Fitness Obesity & Risk of Hypertension
To investigate the role of genetics in cardiorespiratory fitness, obesity, and risk of hypertension.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Obesity
- Trial name
- NCT00083811
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Overweight, Obesity
Cardiovascular Risk Factors in Overweight Adolescents
The aim of the present study was to determine the effects of either a multidisciplinary approach or intensity-controlled interval training on cardiovascular risk factors in overweight adolescents.
- Trial name
- NCT00184236
- Testing
- Multitreatment approach, Aerobic interval training
- Where
- Norway
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Metabolic Syndrome, Hypertension
Development and Multicenter Validation of an AI-Based Remote Photoplethysmography (rPPG) Facial Scan for Multimodal Health Assessment
The goal of this observational study is to learn if a non-contact facial scan using artificial intelligence (AI) can be used to check health status in adults living in urban areas such as Jakarta.
- Conditions
- Metabolic Syndrome, Hypertension, Diabetes (DM), Tachycardia
- Trial name
- NCT07491978
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
PreDiabetes, Abdominal Obesity
Effects of Berberine on Preventing Cardiovascular Disease and Diabetes Mellitus
This multicenter, double-blinded, randomized controlled trial aims to evaluate the effect of berberine on preventing cardiovascular disease and diabetes mellitus among individuals with high cardiometabolic risk in China.
- Conditions
- PreDiabetes, Abdominal Obesity, Hypertension, Dyslipidemias
- Trial name
- ABCD (NCT05749874)
- Testing
- Berberine plus lifestyle intervention
- Where
- China
- Volunteers
- 2,024 people
- Sponsor
- China National Center for Cardiovascular Diseases
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Prehypertension, Hypertension
Be-HealthY: Behavioral Risk Factors for Poor Vascular Health in Youth
The investigators aim to determine the association of dietary intake on cardiovascular disease risk factors among children with overweight and obesity who are being evaluated for elevated blood pressure.
- Conditions
- Prehypertension, Hypertension, Overweight and Obesity, Elevated Blood Pressure
- Trial name
- NCT03934398
- Testing
- Cardiovascular Assessments, Actigraphy, Laboratory assessments
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Johns Hopkins University
Obesity & Overweight
Cardiac Function and Biomarkers in Patients With Obesity and Overweight
Obesity is a major public health problem worldwide and an established risk factor for cardiovascular disease. In individuals with obesity or overweight, systemic inflammation and endothelial dysfunction contribute to myocardial…
- Trial name
- BEYOND (NCT07455630)
- Testing
- Weight loss with pharmacotherapy, Weight loss without pharmacotherapy
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- TecSalud Investigación Clínica
Cardiovascular Diseases, Heart Diseases
Partnership Programs to Reduce Ethnic Differences in the Risk of Cardiovascular Disease
The purpose of this study is to improve cardiovascular disease (CVD) outcomes in racial and ethnic minorities. Specifically, the study seeks to systematically characterize potential ethnic differences in obesity-related CVD by…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity, Metabolic Syndrome X
- Trial name
- META-HEALTH (NCT00101517)
- Where
- 2 sites in United States
- Volunteers
- 4,024 people, healthy volunteers welcome
- Sponsor
- Emory University
Cardiovascular Disease, Obesity
Heart-Healthy Lenoir Lifestyle Study
This study aims to reduce cardiovascular disease (CVD) risk and disparities in risk by improving lifestyle factors which underlie the development of CVD.
- Trial name
- NCT01433484
- Testing
- Maintenance of Weight Loss--Control, Maintenance of Weight Loss--Experimental
- Where
- United States
- Volunteers
- 339 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Type 1 Diabetes Mellitus
Phase Angle and TyG Index as Markers of Glycaemic Control, Adiposity and Cardiovascular Risk in T1D Adolescents
This study aimed to identify new clinical biomarkers that may improve the follow-up and health outcomes of adolescents with type 1 diabetes.
- Trial name
- NCT07021326
- Testing
- there is no intervention
- Where
- Spain
- Volunteers
- 73 people
- Sponsor
- University of Alicante
Diabetes Mellitus, Non-insulin Dependent, Cardiovascular Diseases
Heavy Metals, Obesity and Cardiovascular Risk - Ancillary to Look AHEAD
To evaluate the relationship of baseline toenail chromium concentrations to weight loss, as well as the interaction between heavy metals and the beneficial effects of weight loss.
- Conditions
- Diabetes Mellitus, Non-insulin Dependent, Cardiovascular Diseases, Obesity, Myocardial Infarction
- Trial name
- NCT00031213
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease, Non-significant Coronary Artery Disease
TweeSteden Mild Stenosis Study
Psychosocial factors have been found to be associated with an increased risk for coronary artery disease incidence, progression and worse clinical outcomes.
- Conditions
- Coronary Artery Disease, Non-significant Coronary Artery Disease, Mild Stenosis, Vascular Irregularities
- Trial name
- TWIST (NCT01788241)
- Where
- Netherlands
- Volunteers
- 547 people
- Sponsor
- Tilburg University
Morbid Obesity, Obesity
Resistance Training in Patients With Morbid Obesity
The researchers will conduct a study for avoiding the metabolic syndrome in morbid obese patients. Thus, the aim of the present will be determine the effects of a resistance training programme (RT) in preventing or attenuating…
- Conditions
- Morbid Obesity, Obesity, Physical Activity, Metabolic Syndrome
- Trial name
- ExinMO (NCT03921853)
- Testing
- Behavioral
- Where
- Chile
- Volunteers
- 39 people
- Sponsor
- Universidad de Los Lagos
Obesity
Weight Loss Effects on Heart and Blood Vessel Function in Obesity
Obesity is a growing epidemic and is associated with an increased risk of heart attack and stroke. The investigators know that obesity leads to abnormalities in how the blood vessels and the heart function and that these…
- Trial name
- NCT00782262
- Testing
- KicStart™
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Obesity (Disorder)
Effects of Bariatric Surgery on Cardiovascular Risk Profile in Relation to Inflammatory Parameters: Endothelial Phenotyping and Analysis of the Cross-talk Between Adipose Tissue and Endothelium
This research project aims to study how obesity affects the heart and metabolism, and how these effects change after significant weight loss following bariatric surgery.
- Trial name
- BARIHEART (NCT07131605)
- Testing
- Before bariatric surgery, both blood and biological samples (stool and urine) will be collected. Patients will also undergo a cardiology examination
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- Maria Cecilia Hospital
Colon Cancer, Lung Cancer
Predictive Genetic Risk Assessment Trial
This proof-of-principle clinical trial at Mayo Clinic studies how patients and their physicians understand and utilize predictive genetic risk assessment.
- Conditions
- Colon Cancer, Lung Cancer, Atrial Fibrillation, Diabetes Type 2
- Trial name
- PGT (NCT00782366)
- Testing
- SNP analysis
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity, Cardiovascular Risk Factors
Effects of Soy Based Dietary Supplements on Cardiometabolic Risk Factors.
This study will test the effect of both Luna Rich X© and Reliv Now© against placebo pills or powder (control) on blood lipids. It will also explore the potential effects of these dietary supplements on inflammation markers and…
- Trial name
- NCT02490683
- Testing
- Luna Rich X, Reliv Now
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Loma Linda University