Clinical trials: Obesity and Cardiovascular Risk
Obesity, Childhood, Bariatric Surgery Candidate
Long-Term Outcomes of LSG in Pediatric Patients
This project aims to assess the short- and long-term safety and efficacy of bariatric surgery in children and adolescents compared to adults.
- Conditions
- Obesity, Childhood, Bariatric Surgery Candidate, Cardiovascular Risk Factor
- Trial name
- NCT04136704
- Testing
- Sleeve gastrectomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Saud University
Osteoarthritis Pain, Myocardial Infarction (MI)
Community Physical Exercise Program in Chronic Disease
This study focuses on promoting physical activity (PA) through the implementation of a Community Physical Exercise Program for Chronic Diseases (CPEP-CD), targeting individuals aged 50 years and older with at least two of the…
- Conditions
- Osteoarthritis Pain, Myocardial Infarction (MI), Hypertension, Dyslipidemia
- Trial name
- CPEPCD (NCT06771024)
- Testing
- Physical Exercise
- Where
- Portugal
- Volunteers
- 150 people
- Sponsor
- Associação para o Desenvolvimento do Centro Académico de Investigação e Formação Biomédica do Algarv
Obesity
Effects of Efficient Lifestyle Counseling Method on the Risks of Cardiovascular Disease in Health Care Center Patients
The aim of the trial is to study the effect of a lifestyle change program in patients with obesity and risk of cardiovascular diseases. The main focus is to motivate and support lifestyle changes.
- Trial name
- NCT04425304
- Testing
- Group counseling, Intensive group counseling, Persuasive ICT support
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- University of Oulu
Obesity, Dyslipidemia
Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk
The rise in high fructose corn syrup (HFCS) consumption over the past 40 years since its introduction as a popular sweetener in the United States has led to much concern regarding its contribution to the rise in obesity (1)…
- Conditions
- Obesity, Dyslipidemia, Prediabetes, Dysglycemia
- Trial name
- NCT02702479
- Testing
- High Fructose Corn Syrup, Sucrose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Hypertension
Supermarket and Web-Based Intervention Targeting Nutrition (SuperWIN) for Cardiovascular Risk Reduction
The Supermarket and Web-based Intervention targeting Nutrition (SuperWIN) for cardiovascular risk reduction is a novel, randomized controlled trial aimed at increasing diet quality and decreasing cardiovascular risk.
- Conditions
- Obesity, Hypertension, Hyperlipidemias, Diet Modification
- Trial name
- SuperWIN (NCT03895580)
- Testing
- In-store POP education, Online POP education
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- University of Cincinnati
Hypertension, Overweight
Effects of Different Aerobic Exercise Programs With Nutritional Interventions in Hypertensive and Overweight People
Obesity and arterial hypertension (HTN) frequently coexist in the same patient. Moreover, the concept that obesity and HTN can be additive in terms of cardiovascular rist is widely accepted.
- Conditions
- Hypertension, Overweight, Sedentary
- Trial name
- EXERDIET-HTA (NCT02283047)
- Testing
- DIET, DIET & MODERATE CONTINUOUS TRAINING, DIET & HIGH VOLUME HIIT
- Where
- Spain
- Volunteers
- 176 people
- Sponsor
- University of the Basque Country (UPV/EHU)
Morbid Obesity, Chronic Kidney Disease (Stage 3-4)
Metabolic Status and Risk of Chronic Kidney Disease in French Overseas Populations With Morbid Obesity (OBECAMcohort).
Morbid obesity is defined by a body mass index (BMI) ≥ 40 kg/m2 or > 35 if there is at least one comorbidity (hypertension, diabetes, hypercholesterolemia, joint pain, obstructive sleep apnea syndrome, etc.) Morbid obesity…
- Trial name
- OBECAMcohort (NCT07830030)
- Where
- Guadeloupe
- Volunteers
- 480 people
- Sponsor
- Clinique
Mood Disorders, Hypertension
Association of Mood With Risk for Atherosclerosis
The investigators will aim to determine the association of mood disorders (MDO) with preclinical and clinical cardiovascular (CVD) risk factors among children.
- Conditions
- Mood Disorders, Hypertension, Overweight and Obesity, Vascular Stiffness
- Trial name
- AuRA (NCT04298944)
- Testing
- Cardiovascular Assessments, Actigraphy, Laboratory assessments
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Johns Hopkins University
Overweight and Obesity
Effect of the Probiotic SF68® on Body Composition and Low-to-moderate Cardiovascular Risk
Obesity is a multifactorial disorder of energy balance, characterized by an imbalance between energy intake and energy consumption. In recent decades, the prevalence of obesity has reached epidemic proportions.
- Trial name
- NCT06795607
- Testing
- Probiotic
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Overweight and Obesity
Passive Sensing Technology for Lapse Measurement
Behavioral obesity treatment (BOT) produces clinically significant weight loss and health benefits for many individuals with overweight/obesity and cardiovascular disease (CVD).
- Trial name
- NCT03739151
- Testing
- Behavioral Obesity Treatment
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- The Miriam Hospital
Obesity, Type 2 Diabetes Mellitus
Impact of GBS on CVD in Type 2 Diabetes Mellitus
This research is a NIH single site study with the aims to (1) determine whether surgically induced weight loss decreases the risk of CVD in morbidly obese subjects with T2DM.
- Trial name
- NCT00787670
- Testing
- Diabetes Support and Education, gastric bypass surgery, Tissue Control Group
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Duke University
Obesity, Childhood, Cardiac Disease
Chronotropic Incompetence During Exercise Testing in Obese Adolescents
In adolescents with obesity cardiopulmonary exercise testing (CPET) has become an important clinical examination providing valuable information with regard to the integrative exercise responses, including the pulmonary…
- Conditions
- Obesity, Childhood, Cardiac Disease, Cardiovascular Risk Factor
- Trial name
- NCT04185753
- Testing
- The prevalence of chronotropic incompetence during maximal cardiopulmonary exercise testing
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Hasselt University
Cardiovascular Diseases, Overweight
Enhancing Mental and Physical Health of Women Veterans
Women Veterans are the fastest growing segment of VA users. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that they will want and be able…
- Conditions
- Cardiovascular Diseases, Overweight, Obesity, Smoking
- Trial name
- EMPOWER (NCT05050266)
- Testing
- EBQI, REP
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Type 2 Diabetes Mellitus, Obesity
Injectable Semaglutide vs Dulaglutide in Individuals at Cardiovascular Risk
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials.
- Conditions
- Type 2 Diabetes Mellitus, Obesity, Overweight
- Trial name
- NCT07619495
- Testing
- Semaglutide, Dulaglutide
- Where
- United States
- Volunteers
- 120,000 people
- Sponsor
- Brigham and Women's Hospital
Dyslipidemia, Insulin Resistance Syndrome
Prescription of Step Counts for Targeted Changes in Body Composition and Cardiometabolic Risk in Overweight/Obese Adults
The prevalence of overweight and obesity remains epidemic in the United States, with some of the highest rates seen in older adults.
- Conditions
- Dyslipidemia, Insulin Resistance Syndrome, Hypertension, Inflammation Chronic
- Trial name
- NCT07221279
- Testing
- Step counts for predictable changes in body weight/compositon and cardiometabolic risk
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Insulin Sensitivity, Obstructive Sleep Apnea
Obesity, Sleep Apnea, and Insulin Resistance
Obstructive sleep apnea (OSA) and type 2 diabetes confer increasing economic, social, and public health burdens in the United States.
- Trial name
- NCT02192684
- Testing
- Pioglitazone
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Stanford University
Diabetes Mellitus, Type 2
Effect of Repaglinide Versus Metformin Treatment in Non-Obese Patients With Type-2-Diabetes
Aim: The United Kingdom Prospective Diabetes Study (UKPDS) showed a reduction in cardiovascular events in obese patients with type-2-diabetes treated with metformin compared with other hypoglycaemic treatments with no difference…
- Trial name
- NCT00118963
- Testing
- Metformin, Insulin BIAsp30 (Novolog 70/30), Repaglinide
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Steno Diabetes Center Copenhagen
Obesity
Glycemic Index and CVD: a Crossover Feeding Study
This study will compare the physiological effects of two isoenergetic, nutrient-controlled diets that differ in glycemic index. The diets will be studied in obese adults in a 10-day crossover feeding trial.
- Trial name
- NCT00141076
- Testing
- low vs high glycemic index diet
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Abdominal Obesity, Metabolic Syndrome
WAVE Study- Walking and Aging in VErona Study
Monocentric unblinded two parallel-group randomized controlled trial to evaluate the effect of diet with or without Nordic Walking on weight loss, physical performance and cardiovascular risk factors in overweight and obese…
- Conditions
- Abdominal Obesity, Metabolic Syndrome, Disability Physical, Sarcopenic Obesity
- Trial name
- WAVE (NCT03212391)
- Testing
- Diet, Walking, Nordic Walking
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Cardiovascular Syndrome, Metabolic
High-Intensity Interval Training(HIIT) on Cardio-metabolic Risk in School-age Children
This study aims to evaluate the health promotion effects of high-intensity interval training (HIIT) intervention on school-age children who are at high risk for cardiovascular disease (CVD), as well as the long-term adherence and…
- Trial name
- NCT06416488
- Testing
- HIIT intervention, General health education
- Where
- China
- Volunteers
- 336 people
- Sponsor
- Children's Hospital of Fudan University